Autism spectrum disorder screening with the CBCL/11/2-5: Findings for young children at high risk for autism spectrum disorder / L. A. RESCORLA in Autism, 23-1 (January 2019)  

Public ISBD [article]  inAutism > 23-1 (January 2019) . - p.29-38 Titre : Autism spectrum disorder screening with the CBCL/11/2-5: Findings for young children at high risk for autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : L. A. RESCORLA, Auteur ; Breanna WINDER-PATEL, Auteur ; Sarah J. PATERSON, Auteur ; J. PANDEY, Auteur ; J. J. WOLFF, Auteur ; Robert T. SCHULTZ, Auteur ; J. PIVEN, Auteur Article en page(s) : p.29-38 Langues : Anglais (eng) Mots-clés : autism spectrum disorder screening  baby sibling paradigm  CBCL/11/2-5  Diagnostic and Statistical Manual of Mental Disorders-Pervasive  Developmental Problems scale  familial high-risk  modified checklist  rating-scales  toddlers  identification  cbcl  Psychology Index. décimale : PER Périodiques Résumé : The screening power of the CBCL/11/2-5's Withdrawn and Diagnostic and Statistical Manual of Mental Disorders-Pervasive Developmental Problems (DSM-PDP) scales to identify children diagnosed with autism spectrum disorder at 24 months was tested in a longitudinal, familial high-risk study. Participants were 56 children at high risk for autism spectrum disorder due to an affected older sibling (high-risk group) and 26 low-risk children with a typically developing older sibling (low-risk group). At 24 months, 13 of the 56 high-risk children were diagnosed with autism spectrum disorder, whereas the other 43 were not. The high-risk children diagnosed with autism spectrum disorder group had significantly higher scores on the CBCL/11/2-5's Diagnostic and Statistical Manual of Mental Disorders-Pervasive Developmental Problems and Withdrawn scales than children in the low-risk and high-risk children not diagnosed with autism spectrum disorder groups (eta p2>0.50). Receiver operating characteristic analyses yielded very high area under the curve values (0.91 and 0.89), and a cut point of T > 60 yielded sensitivity of 77% and specificity of 97% to 99% between the high-risk children diagnosed with autism spectrum disorder and the combination of low-risk and high-risk children not diagnosed with autism spectrum disorder. Consistent with several previous studies, the CBCL/11/2-5's Diagnostic and Statistical Manual of Mental Disorders-Pervasive Developmental Problems scale and the Withdrawn syndrome differentiated well between children diagnosed with autism spectrum disorder and those not diagnosed. En ligne : http://dx.doi.org/10.1177/1362361317718482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=379 [article] Autism spectrum disorder screening with the CBCL/11/2-5: Findings for young children at high risk for autism spectrum disorder [Texte imprimé et/ou numérique] / L. A. RESCORLA, Auteur ; Breanna WINDER-PATEL, Auteur ; Sarah J. PATERSON, Auteur ; J. PANDEY, Auteur ; J. J. WOLFF, Auteur ; Robert T. SCHULTZ, Auteur ; J. PIVEN, Auteur . - p.29-38. Langues : Anglais (eng) in Autism > 23-1 (January 2019) . - p.29-38 Mots-clés : autism spectrum disorder screening  baby sibling paradigm  CBCL/11/2-5  Diagnostic and Statistical Manual of Mental Disorders-Pervasive  Developmental Problems scale  familial high-risk  modified checklist  rating-scales  toddlers  identification  cbcl  Psychology Index. décimale : PER Périodiques Résumé : The screening power of the CBCL/11/2-5's Withdrawn and Diagnostic and Statistical Manual of Mental Disorders-Pervasive Developmental Problems (DSM-PDP) scales to identify children diagnosed with autism spectrum disorder at 24 months was tested in a longitudinal, familial high-risk study. Participants were 56 children at high risk for autism spectrum disorder due to an affected older sibling (high-risk group) and 26 low-risk children with a typically developing older sibling (low-risk group). At 24 months, 13 of the 56 high-risk children were diagnosed with autism spectrum disorder, whereas the other 43 were not. The high-risk children diagnosed with autism spectrum disorder group had significantly higher scores on the CBCL/11/2-5's Diagnostic and Statistical Manual of Mental Disorders-Pervasive Developmental Problems and Withdrawn scales than children in the low-risk and high-risk children not diagnosed with autism spectrum disorder groups (eta p2>0.50). Receiver operating characteristic analyses yielded very high area under the curve values (0.91 and 0.89), and a cut point of T > 60 yielded sensitivity of 77% and specificity of 97% to 99% between the high-risk children diagnosed with autism spectrum disorder and the combination of low-risk and high-risk children not diagnosed with autism spectrum disorder. Consistent with several previous studies, the CBCL/11/2-5's Diagnostic and Statistical Manual of Mental Disorders-Pervasive Developmental Problems scale and the Withdrawn syndrome differentiated well between children diagnosed with autism spectrum disorder and those not diagnosed. En ligne : http://dx.doi.org/10.1177/1362361317718482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=379

Fear Potentiated Startle in Children With Autism Spectrum Disorder: Association With Anxiety Symptoms and Amygdala Volume / David HESSL in Autism Research, 14-3 (March 2021)  

Public ISBD [article]  inAutism Research > 14-3 (March 2021) . - p.450-463 Titre : Fear Potentiated Startle in Children With Autism Spectrum Disorder: Association With Anxiety Symptoms and Amygdala Volume Type de document : Texte imprimé et/ou numérique Auteurs : David HESSL, Auteur ; Lauren LIBERO, Auteur ; Andrea SCHNEIDER, Auteur ; Connor M. KERNS, Auteur ; Breanna WINDER-PATEL, Auteur ; Brianna HEATH, Auteur ; Joshua LEE, Auteur ; Cory COLEMAN, Auteur ; Natasha SHARMA, Auteur ; Marjorie SOLOMON, Auteur ; Christine W. NORDAHL, Auteur ; David G. AMARAL, Auteur Article en page(s) : p.450-463 Langues : Anglais (eng) Mots-clés : Mri  anxiety  autism  autistic  fear conditioning Index. décimale : PER Périodiques Résumé : Atypical responses to fearful stimuli and the presence of various forms of anxiety are commonly seen in children with autism spectrum disorder (ASD). The fear potentiated startle paradigm (FPS), which has been studied both in relation to anxiety and as a probe for amygdala function, was carried out in 97 children aged 9-14?years including 48 (12 female) with ASD and 49 (14 female) with typical development (TD). In addition, exploratory analyses were conducted examining the association between FPS and amygdala volume as assessed with magnetic resonance imaging in a subset of the children with ASD with or without an anxiety disorder with available MRI data. While the startle latency was increased in the children with ASD, there was no group difference in FPS. FPS was not significantly associated with traditional Diagnostic and Statistical Manual (DSM) or "autism distinct" forms of anxiety. Within the autism group, FPS was negatively correlated with amygdala volume. Multiple regression analyses revealed that the association between FPS and anxiety severity was significantly moderated by the size of the amygdala, such that the association between FPS and anxiety was significantly more positive in children with larger amygdalas than smaller amygdalas. These findings highlight the heterogeneity of emotional reactivity associated with ASD and the difficulties in establishing biologically meaningful probes of altered brain function. LAY SUMMARY: Many children with autism spectrum disorder (ASD) have additional problems such as anxiety that can greatly impact their lives. How these co-occurring symptoms develop is not well understood. We studied the amygdala, a region of the brain critical for processing fear and a laboratory method called fear potentiated startle for measuring fear conditioning, in children with ASD (with and without an anxiety disorder) and typically developing children. Results showed that the connection between fear conditioning and anxiety is dependent on the size of the amygdala in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2460 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443 [article] Fear Potentiated Startle in Children With Autism Spectrum Disorder: Association With Anxiety Symptoms and Amygdala Volume [Texte imprimé et/ou numérique] / David HESSL, Auteur ; Lauren LIBERO, Auteur ; Andrea SCHNEIDER, Auteur ; Connor M. KERNS, Auteur ; Breanna WINDER-PATEL, Auteur ; Brianna HEATH, Auteur ; Joshua LEE, Auteur ; Cory COLEMAN, Auteur ; Natasha SHARMA, Auteur ; Marjorie SOLOMON, Auteur ; Christine W. NORDAHL, Auteur ; David G. AMARAL, Auteur . - p.450-463. Langues : Anglais (eng) in Autism Research > 14-3 (March 2021) . - p.450-463 Mots-clés : Mri  anxiety  autism  autistic  fear conditioning Index. décimale : PER Périodiques Résumé : Atypical responses to fearful stimuli and the presence of various forms of anxiety are commonly seen in children with autism spectrum disorder (ASD). The fear potentiated startle paradigm (FPS), which has been studied both in relation to anxiety and as a probe for amygdala function, was carried out in 97 children aged 9-14?years including 48 (12 female) with ASD and 49 (14 female) with typical development (TD). In addition, exploratory analyses were conducted examining the association between FPS and amygdala volume as assessed with magnetic resonance imaging in a subset of the children with ASD with or without an anxiety disorder with available MRI data. While the startle latency was increased in the children with ASD, there was no group difference in FPS. FPS was not significantly associated with traditional Diagnostic and Statistical Manual (DSM) or "autism distinct" forms of anxiety. Within the autism group, FPS was negatively correlated with amygdala volume. Multiple regression analyses revealed that the association between FPS and anxiety severity was significantly moderated by the size of the amygdala, such that the association between FPS and anxiety was significantly more positive in children with larger amygdalas than smaller amygdalas. These findings highlight the heterogeneity of emotional reactivity associated with ASD and the difficulties in establishing biologically meaningful probes of altered brain function. LAY SUMMARY: Many children with autism spectrum disorder (ASD) have additional problems such as anxiety that can greatly impact their lives. How these co-occurring symptoms develop is not well understood. We studied the amygdala, a region of the brain critical for processing fear and a laboratory method called fear potentiated startle for measuring fear conditioning, in children with ASD (with and without an anxiety disorder) and typically developing children. Results showed that the connection between fear conditioning and anxiety is dependent on the size of the amygdala in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2460 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443

A Pilot Randomized Controlled Trial of the ACCESS Program: A Group Intervention to Improve Social, Adaptive Functioning, Stress Coping, and Self-Determination Outcomes in Young Adults with Autism Spectrum Disorder / T. M. OSWALD in Journal of Autism and Developmental Disorders, 48-5 (May 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1742-1760 Titre : A Pilot Randomized Controlled Trial of the ACCESS Program: A Group Intervention to Improve Social, Adaptive Functioning, Stress Coping, and Self-Determination Outcomes in Young Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : T. M. OSWALD, Auteur ; Breanna WINDER-PATEL, Auteur ; S. RUDER, Auteur ; G. XING, Auteur ; A. STAHMER, Auteur ; M. SOLOMON, Auteur Article en page(s) : p.1742-1760 Langues : Anglais (eng) Mots-clés : Adults  Autism Spectrum Disorder  CBT for Anxiety  Randomized controlled trial  Self-determination  Social skills Index. décimale : PER Périodiques Résumé : The purpose of this pilot randomized controlled trial was to investigate the acceptability and efficacy of the Acquiring Career, Coping, Executive control, Social Skills (ACCESS) Program, a group intervention tailored for young adults with autism spectrum disorder (ASD) to enhance critical skills and beliefs that promote adult functioning, including social and adaptive skills, self-determination skills, and coping self-efficacy. Forty-four adults with ASD (ages 18-38; 13 females) and their caregivers were randomly assigned to treatment or waitlist control. Compared to controls, adults in treatment significantly improved in adaptive and self-determination skills, per caregiver report, and self-reported greater belief in their ability to access social support to cope with stressors. Results provide evidence for the acceptability and efficacy of the ACCESS Program. En ligne : http://dx.doi.org/10.1007/s10803-017-3421-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355 [article] A Pilot Randomized Controlled Trial of the ACCESS Program: A Group Intervention to Improve Social, Adaptive Functioning, Stress Coping, and Self-Determination Outcomes in Young Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / T. M. OSWALD, Auteur ; Breanna WINDER-PATEL, Auteur ; S. RUDER, Auteur ; G. XING, Auteur ; A. STAHMER, Auteur ; M. SOLOMON, Auteur . - p.1742-1760. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1742-1760 Mots-clés : Adults  Autism Spectrum Disorder  CBT for Anxiety  Randomized controlled trial  Self-determination  Social skills Index. décimale : PER Périodiques Résumé : The purpose of this pilot randomized controlled trial was to investigate the acceptability and efficacy of the Acquiring Career, Coping, Executive control, Social Skills (ACCESS) Program, a group intervention tailored for young adults with autism spectrum disorder (ASD) to enhance critical skills and beliefs that promote adult functioning, including social and adaptive skills, self-determination skills, and coping self-efficacy. Forty-four adults with ASD (ages 18-38; 13 females) and their caregivers were randomly assigned to treatment or waitlist control. Compared to controls, adults in treatment significantly improved in adaptive and self-determination skills, per caregiver report, and self-reported greater belief in their ability to access social support to cope with stressors. Results provide evidence for the acceptability and efficacy of the ACCESS Program. En ligne : http://dx.doi.org/10.1007/s10803-017-3421-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355

The Importance of Temperament for Understanding Early Manifestations of Autism Spectrum Disorder in High-Risk Infants / Sarah J. PATERSON in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2849-2863 Titre : The Importance of Temperament for Understanding Early Manifestations of Autism Spectrum Disorder in High-Risk Infants Type de document : Texte imprimé et/ou numérique Auteurs : Sarah J. PATERSON, Auteur ; J. J. WOLFF, Auteur ; J. T. ELISON, Auteur ; Breanna WINDER-PATEL, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; A. ESTES, Auteur ; J. PANDEY, Auteur ; Robert T. SCHULTZ, Auteur ; Kelly N. BOTTERON, Auteur ; Stephen R. DAGER, Auteur ; Heather C. HAZLETT, Auteur ; J. PIVEN, Auteur Article en page(s) : p.2849-2863 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Infancy  Temperament Index. décimale : PER Périodiques Résumé : The present study investigated the relationship between infant temperament characteristics and autism spectrum disorder (ASD) risk status. Temperament was examined at 6, 12, and 24 months in 282 infants at high familial risk for ASD and 114 low-risk controls using the Infant Behavior Questionnaire-Revised and Early Childhood Behavior Questionnaire. Infants were divided into three groups at 24 months: High-Risk Positive-classified as ASD (HR Pos), High-Risk Negative (HR Neg), and Low-Risk Negative (LR Neg). At 6 and 12 months HR Pos infants exhibited lower Surgency and Regulatory Capacity than LR Neg infants. By 12 months they also demonstrated increased Negative Affect. Group differences remained, when early signs of ASD were controlled for, suggesting that temperament differences could be useful targets for understanding the development of ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04003-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] The Importance of Temperament for Understanding Early Manifestations of Autism Spectrum Disorder in High-Risk Infants [Texte imprimé et/ou numérique] / Sarah J. PATERSON, Auteur ; J. J. WOLFF, Auteur ; J. T. ELISON, Auteur ; Breanna WINDER-PATEL, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; A. ESTES, Auteur ; J. PANDEY, Auteur ; Robert T. SCHULTZ, Auteur ; Kelly N. BOTTERON, Auteur ; Stephen R. DAGER, Auteur ; Heather C. HAZLETT, Auteur ; J. PIVEN, Auteur . - p.2849-2863. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2849-2863 Mots-clés : Autism spectrum disorder  Infancy  Temperament Index. décimale : PER Périodiques Résumé : The present study investigated the relationship between infant temperament characteristics and autism spectrum disorder (ASD) risk status. Temperament was examined at 6, 12, and 24 months in 282 infants at high familial risk for ASD and 114 low-risk controls using the Infant Behavior Questionnaire-Revised and Early Childhood Behavior Questionnaire. Infants were divided into three groups at 24 months: High-Risk Positive-classified as ASD (HR Pos), High-Risk Negative (HR Neg), and Low-Risk Negative (LR Neg). At 6 and 12 months HR Pos infants exhibited lower Surgency and Regulatory Capacity than LR Neg infants. By 12 months they also demonstrated increased Negative Affect. Group differences remained, when early signs of ASD were controlled for, suggesting that temperament differences could be useful targets for understanding the development of ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04003-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

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