Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development / Carolyn G. DIGUISEPPI ; Tessa CRUME ; Brady HOLST ; Kaylynn AIONA ; Julia VAN DYKE ; Lisa A. CROEN ; Julie L. DANIELS ; Sandra FRIEDMAN ; Katherine R. SABOURIN ; Laura A. SCHIEVE ; Lisa WIGGINS ; Gayle C. WINDHAM ; Cordelia ROBINSON ROSENBERG in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.202-216 Titre : Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development : Autism Research Type de document : texte imprimé Auteurs : Carolyn G. DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Brady HOLST, Auteur ; Kaylynn AIONA, Auteur ; Julia VAN DYKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Sandra FRIEDMAN, Auteur ; Katherine R. SABOURIN, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa WIGGINS, Auteur ; Gayle C. WINDHAM, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur Article en page(s) : p.202-216 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  cannabis  child behavior  child preschool  developmental disabilities  pregnancy  prenatal risk factors  sleep wake disorders Index. décimale : PER Périodiques Résumé : Abstract Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3 months preconception through delivery (?peripregnancy?) with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30 68 months with ASD symptoms (i.e., met study criteria for ASD or had ASD symptoms on standardized assessments or community ASD diagnosis, N 2734) and without ASD symptoms (other developmental delay/disorders or general population sample, N 3454) were evaluated with the Child Behavior Checklist and Mullen Scales of Early Learning. We examined cannabis use during three time periods: peripregnancy, pregnancy, and only preconception. Peripregnancy cannabis exposure was reported for 6.0% of children with and 4.6% of children without ASD symptoms. Preconception-only cannabis use (versus no use) was associated with more aggressive behavior, emotional reactivity, and sleep problems in children with ASD symptoms, but not in children without ASD symptoms. Cannabis use during pregnancy was associated with increased attention and sleep problems in children with ASD symptoms; these associations did not differ significantly by ASD symptoms. Peripregnancy cannabis use was not associated with child developmental abilities regardless of ASD symptoms. In summary, associations of peripregnancy cannabis use with some behavioral outcomes differed in children with and without ASD symptoms. With rising cannabis use among pregnant women, future studies that examine a range of developmental risks associated with timing and patterns of cannabis use prior to conception as well as during pregnancy could inform clinical guidance. En ligne : https://doi.org/10.1002/aur.3284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development : Autism Research [texte imprimé] / Carolyn G. DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Brady HOLST, Auteur ; Kaylynn AIONA, Auteur ; Julia VAN DYKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Sandra FRIEDMAN, Auteur ; Katherine R. SABOURIN, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa WIGGINS, Auteur ; Gayle C. WINDHAM, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur . - p.202-216. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.202-216 Mots-clés : autism spectrum disorder  cannabis  child behavior  child preschool  developmental disabilities  pregnancy  prenatal risk factors  sleep wake disorders Index. décimale : PER Périodiques Résumé : Abstract Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3 months preconception through delivery (?peripregnancy?) with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30 68 months with ASD symptoms (i.e., met study criteria for ASD or had ASD symptoms on standardized assessments or community ASD diagnosis, N 2734) and without ASD symptoms (other developmental delay/disorders or general population sample, N 3454) were evaluated with the Child Behavior Checklist and Mullen Scales of Early Learning. We examined cannabis use during three time periods: peripregnancy, pregnancy, and only preconception. Peripregnancy cannabis exposure was reported for 6.0% of children with and 4.6% of children without ASD symptoms. Preconception-only cannabis use (versus no use) was associated with more aggressive behavior, emotional reactivity, and sleep problems in children with ASD symptoms, but not in children without ASD symptoms. Cannabis use during pregnancy was associated with increased attention and sleep problems in children with ASD symptoms; these associations did not differ significantly by ASD symptoms. Peripregnancy cannabis use was not associated with child developmental abilities regardless of ASD symptoms. In summary, associations of peripregnancy cannabis use with some behavioral outcomes differed in children with and without ASD symptoms. With rising cannabis use among pregnant women, future studies that examine a range of developmental risks associated with timing and patterns of cannabis use prior to conception as well as during pregnancy could inform clinical guidance. En ligne : https://doi.org/10.1002/aur.3284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Features that best define the heterogeneity and homogeneity of autism in preschool-age children: A multisite case?control analysis replicated across two independent samples / Lisa D. WIGGINS in Autism Research, 15-3 (March 2022)  

Public ISBD [article]  inAutism Research > 15-3 (March 2022) . - p.539-550 Titre : Features that best define the heterogeneity and homogeneity of autism in preschool-age children: A multisite case?control analysis replicated across two independent samples Type de document : texte imprimé Auteurs : Lisa D. WIGGINS, Auteur ; Lin H. TIAN, Auteur ; Eric RUBENSTEIN, Auteur ; Laura A. SCHIEVE, Auteur ; Julie L. DANIELS, Auteur ; Karen PAZOL, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; Brian D. BARGER, Auteur ; Eric J. MOODY, Auteur ; Steven A. ROSENBERG, Auteur ; Chyrise BRADLEY, Auteur ; Melanie HSU, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur ; Deborah CHRISTENSEN, Auteur ; Tessa CRUME, Auteur ; Juhi PANDEY, Auteur ; Susan E. LEVY, Auteur Article en page(s) : p.539-550 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract The heterogeneous nature of children with symptoms of autism spectrum disorder (ASD) makes it difficult to identify risk factors and effective treatment options. We sought to identify behavioral and developmental features that best define the heterogeneity and homogeneity in 2 5-year-old children classified with ASD and subthreshold ASD characteristics. Children were enrolled in a multisite case?control study of ASD. Detailed behavioral and developmental data were gathered by maternal telephone interview, parent-administered questionnaires, child cognitive evaluation, and ASD diagnostic measures. Participants with a positive ASD screen score or prior ASD diagnosis were referred for comprehensive evaluation. Children in the ASD group met study criteria based on this evaluation; children who did not meet study criteria were categorized as having subthreshold ASD characteristics. There were 1480 children classified as ASD (81.6% boys) and 594 children classified as having subthreshold ASD characteristics (70.2% boys) in the sample. Factors associated with dysregulation (e.g., aggression, anxiety/depression, sleep problems) followed by developmental abilities (e.g., expressive and receptive language skills) most contributed to heterogeneity in both groups of children. Atypical sensory response contributed to homogeneity in children classified as ASD but not those with subthreshold characteristics. These findings suggest that dysregulation and developmental abilities are clinical features that can impact functioning in children with ASD and other DD, and that documenting these features in pediatric records may help meet the needs of the individual child. Sensory dysfunction could be considered a core feature of ASD and thus used to inform more targeted screening, evaluation, treatment, and research efforts. Lay summary The diverse nature of autism spectrum disorder (ASD) makes it difficult to find risk factors and treatment options. We identified the most dissimilar and most similar symptom(s) in children classified as ASD and as having subthreshold ASD characteristics. Factors associated with dysregulation and developmental abilities contributed to diversity in both groups of children. Sensory dysfunction was the most common symptom in children with ASD but not those with subthreshold characteristics. Findings can inform clinical practice and research. En ligne : https://doi.org/10.1002/aur.2663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473 [article] Features that best define the heterogeneity and homogeneity of autism in preschool-age children: A multisite case?control analysis replicated across two independent samples [texte imprimé] / Lisa D. WIGGINS, Auteur ; Lin H. TIAN, Auteur ; Eric RUBENSTEIN, Auteur ; Laura A. SCHIEVE, Auteur ; Julie L. DANIELS, Auteur ; Karen PAZOL, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; Brian D. BARGER, Auteur ; Eric J. MOODY, Auteur ; Steven A. ROSENBERG, Auteur ; Chyrise BRADLEY, Auteur ; Melanie HSU, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur ; Deborah CHRISTENSEN, Auteur ; Tessa CRUME, Auteur ; Juhi PANDEY, Auteur ; Susan E. LEVY, Auteur . - p.539-550. Langues : Anglais (eng) in Autism Research > 15-3 (March 2022) . - p.539-550 Index. décimale : PER Périodiques Résumé : Abstract The heterogeneous nature of children with symptoms of autism spectrum disorder (ASD) makes it difficult to identify risk factors and effective treatment options. We sought to identify behavioral and developmental features that best define the heterogeneity and homogeneity in 2 5-year-old children classified with ASD and subthreshold ASD characteristics. Children were enrolled in a multisite case?control study of ASD. Detailed behavioral and developmental data were gathered by maternal telephone interview, parent-administered questionnaires, child cognitive evaluation, and ASD diagnostic measures. Participants with a positive ASD screen score or prior ASD diagnosis were referred for comprehensive evaluation. Children in the ASD group met study criteria based on this evaluation; children who did not meet study criteria were categorized as having subthreshold ASD characteristics. There were 1480 children classified as ASD (81.6% boys) and 594 children classified as having subthreshold ASD characteristics (70.2% boys) in the sample. Factors associated with dysregulation (e.g., aggression, anxiety/depression, sleep problems) followed by developmental abilities (e.g., expressive and receptive language skills) most contributed to heterogeneity in both groups of children. Atypical sensory response contributed to homogeneity in children classified as ASD but not those with subthreshold characteristics. These findings suggest that dysregulation and developmental abilities are clinical features that can impact functioning in children with ASD and other DD, and that documenting these features in pediatric records may help meet the needs of the individual child. Sensory dysfunction could be considered a core feature of ASD and thus used to inform more targeted screening, evaluation, treatment, and research efforts. Lay summary The diverse nature of autism spectrum disorder (ASD) makes it difficult to find risk factors and treatment options. We identified the most dissimilar and most similar symptom(s) in children classified as ASD and as having subthreshold ASD characteristics. Factors associated with dysregulation and developmental abilities contributed to diversity in both groups of children. Sensory dysfunction was the most common symptom in children with ASD but not those with subthreshold characteristics. Findings can inform clinical practice and research. En ligne : https://doi.org/10.1002/aur.2663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=473

Peri-Pregnancy Cannabis Use and Autism Spectrum Disorder in the Offspring: Findings from the Study to Explore Early Development / Carolyn G. DIGUISEPPI in Journal of Autism and Developmental Disorders, 52-11 (November 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-11 (November 2022) . - p.5064-5071 Titre : Peri-Pregnancy Cannabis Use and Autism Spectrum Disorder in the Offspring: Findings from the Study to Explore Early Development Type de document : texte imprimé Auteurs : Carolyn G. DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Julia VAN DYKE, Auteur ; Katherine R. SABOURIN, Auteur ; Gnakub N. SOKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Li-Ching LEE, Auteur ; Laura A. SCHIEVE, Auteur ; Gayle C. WINDHAM, Auteur ; Sandra FRIEDMAN, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur Article en page(s) : p.5064-5071 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/epidemiology  Cannabis/adverse effects  Case-Control Studies  Female  Humans  Pregnancy  Autism spectrum disorder  Cannabis  Epidemiology  Marijuana  interest. Index. décimale : PER Périodiques Résumé : The association of autism spectrum disorder (ASD) with self-reported maternal cannabis use from 3 months pre-conception to delivery ("peri-pregnancy") was assessed in children aged 30-68 months, born 2003 to 2011. Children with ASD (N=1428) were compared to children with other developmental delays/disorders (DD, N=1198) and population controls (POP, N=1628). Peri-pregnancy cannabis use was reported for 5.2% of ASD, 3.2% of DD and 4.4% of POP children. Adjusted odds of peri-pregnancy cannabis use did not differ significantly between ASD cases and DD or POP controls. Results were similar for any use during pregnancy. However, given potential risks suggested by underlying neurobiology and animal models, further studies in more recent cohorts, in which cannabis use and perception may have changed, are needed. En ligne : http://dx.doi.org/10.1007/s10803-021-05339-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489 [article] Peri-Pregnancy Cannabis Use and Autism Spectrum Disorder in the Offspring: Findings from the Study to Explore Early Development [texte imprimé] / Carolyn G. DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Julia VAN DYKE, Auteur ; Katherine R. SABOURIN, Auteur ; Gnakub N. SOKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Li-Ching LEE, Auteur ; Laura A. SCHIEVE, Auteur ; Gayle C. WINDHAM, Auteur ; Sandra FRIEDMAN, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur . - p.5064-5071. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-11 (November 2022) . - p.5064-5071 Mots-clés : Autism Spectrum Disorder/epidemiology  Cannabis/adverse effects  Case-Control Studies  Female  Humans  Pregnancy  Autism spectrum disorder  Cannabis  Epidemiology  Marijuana  interest. Index. décimale : PER Périodiques Résumé : The association of autism spectrum disorder (ASD) with self-reported maternal cannabis use from 3 months pre-conception to delivery ("peri-pregnancy") was assessed in children aged 30-68 months, born 2003 to 2011. Children with ASD (N=1428) were compared to children with other developmental delays/disorders (DD, N=1198) and population controls (POP, N=1628). Peri-pregnancy cannabis use was reported for 5.2% of ASD, 3.2% of DD and 4.4% of POP children. Adjusted odds of peri-pregnancy cannabis use did not differ significantly between ASD cases and DD or POP controls. Results were similar for any use during pregnancy. However, given potential risks suggested by underlying neurobiology and animal models, further studies in more recent cohorts, in which cannabis use and perception may have changed, are needed. En ligne : http://dx.doi.org/10.1007/s10803-021-05339-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489

Prenatal Maternal Alcohol Exposure During the First Trimester of Pregnancy in Relation to Early Learning Ability, Behavioral Problems, and Autistic Traits in Preschool Children With or Without Autism Spectrum Disorder / Brian D. BARGER ; Karen PAZOL ; Laura A. SCHIEVE ; Jacquelyn BERTRAND ; Carolyn G. DIGUISEPPI ; April D. SUMMERS ; Alicia DUNAJCIK ; Lucinda J. ENGLAND ; Tessa CRUME ; Lisa D. WIGGINS in Autism Research, 18-5 (May 2025)  

Public ISBD [article]  inAutism Research > 18-5 (May 2025) . - p.1087-1096 Titre : Prenatal Maternal Alcohol Exposure During the First Trimester of Pregnancy in Relation to Early Learning Ability, Behavioral Problems, and Autistic Traits in Preschool Children With or Without Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Brian D. BARGER, Auteur ; Karen PAZOL, Auteur ; Laura A. SCHIEVE, Auteur ; Jacquelyn BERTRAND, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; April D. SUMMERS, Auteur ; Alicia DUNAJCIK, Auteur ; Lucinda J. ENGLAND, Auteur ; Tessa CRUME, Auteur ; Lisa D. WIGGINS, Auteur Article en page(s) : p.1087-1096 Langues : Anglais (eng) Mots-clés : alcohol  autism  behaviors  learning delays  neurodevelopment Index. décimale : PER Périodiques Résumé : ABSTRACT Prenatal alcohol exposure has been linked to adverse neurodevelopmental outcomes. However, its effects on developmental outcomes in children with autism spectrum disorder (ASD) remain unclear. We examined associations between prenatal alcohol exposure during the first trimester (PAE-FT) and early learning ability, behavioral problems, and severity of autistic traits in preschool-aged children in a large multi-site case?control study, the Study to Explore Early Development. Children were classified as ASD (n 1237) or population comparison without ASD (POP, n 1334) after an in-person assessment covering cognitive abilities and detailed autistic traits. Mothers completed questionnaires on their child's behavior and autism-related traits, as well as their alcohol use during pregnancy. Of children in the ASD and POP groups, 18.5% and 20.2%, respectively, were exposed to PAE-FT. Exposure to 3 or more alcoholic drinks per week was associated with increased externalizing behaviors (i.e., attention deficits and aggressive behaviors) in children in both the ASD and POP groups, and with exacerbated social communication and interaction deficits in children with ASD only. First trimester exposure to 1 2 alcoholic drinks per week was associated with early learning delays for children in the ASD group, but not the POP group. As expected, our findings suggest that PAE-FT is associated with adverse behavioral development of children regardless of ASD status. However, PAE-FT may exacerbate autism-specific developmental problems and learning difficulties in children with ASD. Gathering a prenatal alcohol exposure history for children with and without ASD could contribute to a better understanding of developmental trajectories, aiding informed decisions for interventions and support. En ligne : https://doi.org/10.1002/aur.70025 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558 [article] Prenatal Maternal Alcohol Exposure During the First Trimester of Pregnancy in Relation to Early Learning Ability, Behavioral Problems, and Autistic Traits in Preschool Children With or Without Autism Spectrum Disorder [texte imprimé] / Brian D. BARGER, Auteur ; Karen PAZOL, Auteur ; Laura A. SCHIEVE, Auteur ; Jacquelyn BERTRAND, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; April D. SUMMERS, Auteur ; Alicia DUNAJCIK, Auteur ; Lucinda J. ENGLAND, Auteur ; Tessa CRUME, Auteur ; Lisa D. WIGGINS, Auteur . - p.1087-1096. Langues : Anglais (eng) in Autism Research > 18-5 (May 2025) . - p.1087-1096 Mots-clés : alcohol  autism  behaviors  learning delays  neurodevelopment Index. décimale : PER Périodiques Résumé : ABSTRACT Prenatal alcohol exposure has been linked to adverse neurodevelopmental outcomes. However, its effects on developmental outcomes in children with autism spectrum disorder (ASD) remain unclear. We examined associations between prenatal alcohol exposure during the first trimester (PAE-FT) and early learning ability, behavioral problems, and severity of autistic traits in preschool-aged children in a large multi-site case?control study, the Study to Explore Early Development. Children were classified as ASD (n 1237) or population comparison without ASD (POP, n 1334) after an in-person assessment covering cognitive abilities and detailed autistic traits. Mothers completed questionnaires on their child's behavior and autism-related traits, as well as their alcohol use during pregnancy. Of children in the ASD and POP groups, 18.5% and 20.2%, respectively, were exposed to PAE-FT. Exposure to 3 or more alcoholic drinks per week was associated with increased externalizing behaviors (i.e., attention deficits and aggressive behaviors) in children in both the ASD and POP groups, and with exacerbated social communication and interaction deficits in children with ASD only. First trimester exposure to 1 2 alcoholic drinks per week was associated with early learning delays for children in the ASD group, but not the POP group. As expected, our findings suggest that PAE-FT is associated with adverse behavioral development of children regardless of ASD status. However, PAE-FT may exacerbate autism-specific developmental problems and learning difficulties in children with ASD. Gathering a prenatal alcohol exposure history for children with and without ASD could contribute to a better understanding of developmental trajectories, aiding informed decisions for interventions and support. En ligne : https://doi.org/10.1002/aur.70025 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558

Proximity of Maternal Time of Immigration to Child's Birth Is Associated With Autism Spectrum Disorder With Early Learning Delay Among Immigrant Populations in the United States: Findings From the Study to Explore Early Development / Kaylynn AIONA in Autism Research, 18-12 (December 2025)  

Public ISBD [article]  inAutism Research > 18-12 (December 2025) . - p.2419-2430 Titre : Proximity of Maternal Time of Immigration to Child's Birth Is Associated With Autism Spectrum Disorder With Early Learning Delay Among Immigrant Populations in the United States: Findings From the Study to Explore Early Development Type de document : texte imprimé Auteurs : Kaylynn AIONA, Auteur ; Tessa CRUME, Auteur ; Nuri REYES, Auteur ; Sarah J. SCHMIEGE, Auteur ; Janine YOUNG, Auteur ; Brady HOLST, Auteur ; Maureen S. DURKIN, Auteur ; Melissa MAGALLANES, Auteur ; Carolyn DIGUISEPPI, Auteur Article en page(s) : p.2419-2430 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  early learning delay  health disparities  immigrant  intellectual disability  migrant Index. décimale : PER Périodiques Résumé : ABSTRACT Our objective was to examine the relationship between the timing of parental US immigration and autism spectrum disorder (ASD) without early learning delay (ELD), ASD with ELD, and ELD alone among US-born children. We analyzed data from a multi-site case?control study that recruited children aged 2?5?years with ASD or non-ASD developmental disorders and same-age population controls. Parental demographics were collected from caregivers at study enrollment. Mullen Scales of Early Learning ≤?70 was used to define ELD. Among children with a non-US-born parent (N?=?1048), we used multinomial logistic regression to examine time from parental immigration to the child's birth in relation to ASD alone, ASD with ELD (ASD?+?ELD), and ELD alone compared to population controls. Having a non-US-born mother (regardless of the father's birthplace) versus a non-US-born father only was evaluated as a potential effect modifier. Among those with a non-US-born mother, closer proximity of maternal time of immigration to the child's birth is associated with increased odds for ASD?+?ELD and ELD alone. There was no significant association between years since US arrival and ASD alone. Among those with a non-US-born father only, we did not observe a significant relationship between time since paternal US arrival and ASD/ELD categories. Our study suggests that time-varying exposures among immigrant mothers may be of importance for the development of ASD?+?ELD and ELD alone in the offspring. These results may inform research into the etiology of ASD and ELD and ways to support immigrant women of childbearing age. En ligne : https://doi.org/10.1002/aur.70133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578 [article] Proximity of Maternal Time of Immigration to Child's Birth Is Associated With Autism Spectrum Disorder With Early Learning Delay Among Immigrant Populations in the United States: Findings From the Study to Explore Early Development [texte imprimé] / Kaylynn AIONA, Auteur ; Tessa CRUME, Auteur ; Nuri REYES, Auteur ; Sarah J. SCHMIEGE, Auteur ; Janine YOUNG, Auteur ; Brady HOLST, Auteur ; Maureen S. DURKIN, Auteur ; Melissa MAGALLANES, Auteur ; Carolyn DIGUISEPPI, Auteur . - p.2419-2430. Langues : Anglais (eng) in Autism Research > 18-12 (December 2025) . - p.2419-2430 Mots-clés : autism spectrum disorder  early learning delay  health disparities  immigrant  intellectual disability  migrant Index. décimale : PER Périodiques Résumé : ABSTRACT Our objective was to examine the relationship between the timing of parental US immigration and autism spectrum disorder (ASD) without early learning delay (ELD), ASD with ELD, and ELD alone among US-born children. We analyzed data from a multi-site case?control study that recruited children aged 2?5?years with ASD or non-ASD developmental disorders and same-age population controls. Parental demographics were collected from caregivers at study enrollment. Mullen Scales of Early Learning ≤?70 was used to define ELD. Among children with a non-US-born parent (N?=?1048), we used multinomial logistic regression to examine time from parental immigration to the child's birth in relation to ASD alone, ASD with ELD (ASD?+?ELD), and ELD alone compared to population controls. Having a non-US-born mother (regardless of the father's birthplace) versus a non-US-born father only was evaluated as a potential effect modifier. Among those with a non-US-born mother, closer proximity of maternal time of immigration to the child's birth is associated with increased odds for ASD?+?ELD and ELD alone. There was no significant association between years since US arrival and ASD alone. Among those with a non-US-born father only, we did not observe a significant relationship between time since paternal US arrival and ASD/ELD categories. Our study suggests that time-varying exposures among immigrant mothers may be of importance for the development of ASD?+?ELD and ELD alone in the offspring. These results may inform research into the etiology of ASD and ELD and ways to support immigrant women of childbearing age. En ligne : https://doi.org/10.1002/aur.70133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578

Resilience to COVID-19-related challenges in preschool-aged children with and without autism spectrum disorder / Eric J. MOODY in Research in Autism, 128 (October 2025)  

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