Adaptive and Behavioral Profiles in Down Syndrome and Co-Occurring Autism Spectrum Disorder: A Case-Control Study / Elisa FUCA ; Stefano VICARI ; Floriana COSTANZO in Autism Research, 18-2 (February 2025)  

Public ISBD [article]  inAutism Research > 18-2 (February 2025) . - p.362-369 Titre : Adaptive and Behavioral Profiles in Down Syndrome and Co-Occurring Autism Spectrum Disorder: A Case-Control Study : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Elisa FUCA, Auteur ; Stefano VICARI, Auteur ; Floriana COSTANZO, Auteur Article en page(s) : p.362-369 Langues : Anglais (eng) Mots-clés : Aberrant Behavior Checklist diagnosis intellectual disability repetitive behaviors Index. décimale : PER Périodiques Résumé : ABSTRACT Down syndrome (DS) is the most frequent genetic cause of intellectual disability (ID). Individuals with DS exhibit an elevated risk of other neurodevelopmental disorders, including autism spectrum disorder (ASD). The primary objective of this study was to explore the clinical characteristics of co-occurring ASD in children and adolescents with DS using a case?control approach. We compared the adaptive and behavioral profiles of a group of participants with both DS and ASD (ASD group) with a group of participants with DS-only matched by age, sex, and IQ (CON group). Participants in the ASD group exhibited significantly lower adaptive skills than the CON group, despite the IQ-matching in the moderate/severe ID range. No group differences emerged on internalizing or externalizing behavioral symptoms, but participants in the ASD group exhibited significantly higher social withdrawal, stereotyped behavior, and restricted interests. These findings indicate that, although children with DS?with or without ASD?who have similar low cognitive functioning often exhibit common behavioral traits, paying close attention to the elevation of stereotyped behaviors or restricted interests can improve the detection of co-occurring ASD in this population, enabling more personalized interventions. Conversely, the presence of ritualistic behaviors or behaviors related to insistence on sameness may not be a strong indicator of underlying ASD in children with DS. Additionally, acknowledging that the presence of ASD contributes to adaptive behavior deficits beyond the impact of moderate-to-severe ID alone highlights the critical need for early interventions to enhance daily living skills in this population. En ligne : https://doi.org/10.1002/aur.3294 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=547 [article] Adaptive and Behavioral Profiles in Down Syndrome and Co-Occurring Autism Spectrum Disorder: A Case-Control Study : Autism Research [Texte imprimé et/ou numérique] / Elisa FUCA, Auteur ; Stefano VICARI, Auteur ; Floriana COSTANZO, Auteur . - p.362-369. Langues : Anglais (eng) in Autism Research > 18-2 (February 2025) . - p.362-369 Mots-clés : Aberrant Behavior Checklist diagnosis intellectual disability repetitive behaviors Index. décimale : PER Périodiques Résumé : ABSTRACT Down syndrome (DS) is the most frequent genetic cause of intellectual disability (ID). Individuals with DS exhibit an elevated risk of other neurodevelopmental disorders, including autism spectrum disorder (ASD). The primary objective of this study was to explore the clinical characteristics of co-occurring ASD in children and adolescents with DS using a case?control approach. We compared the adaptive and behavioral profiles of a group of participants with both DS and ASD (ASD group) with a group of participants with DS-only matched by age, sex, and IQ (CON group). Participants in the ASD group exhibited significantly lower adaptive skills than the CON group, despite the IQ-matching in the moderate/severe ID range. No group differences emerged on internalizing or externalizing behavioral symptoms, but participants in the ASD group exhibited significantly higher social withdrawal, stereotyped behavior, and restricted interests. These findings indicate that, although children with DS?with or without ASD?who have similar low cognitive functioning often exhibit common behavioral traits, paying close attention to the elevation of stereotyped behaviors or restricted interests can improve the detection of co-occurring ASD in this population, enabling more personalized interventions. Conversely, the presence of ritualistic behaviors or behaviors related to insistence on sameness may not be a strong indicator of underlying ASD in children with DS. Additionally, acknowledging that the presence of ASD contributes to adaptive behavior deficits beyond the impact of moderate-to-severe ID alone highlights the critical need for early interventions to enhance daily living skills in this population. En ligne : https://doi.org/10.1002/aur.3294 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=547

Cross-cultural similarities and differences in reporting autistic symptoms in toddlers: A study synthesizing M-CHAT(-R) data from ten countries / Dejan STEVANOVIC in Research in Autism Spectrum Disorders, 95 (July 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 95 (July 2022) . - 101984 Titre : Cross-cultural similarities and differences in reporting autistic symptoms in toddlers: A study synthesizing M-CHAT(-R) data from ten countries Type de document : Texte imprimé et/ou numérique Auteurs : Dejan STEVANOVIC, Auteur ; Diana L. ROBINS, Auteur ; Floriana COSTANZO, Auteur ; Elisa FUCA, Auteur ; Giovanni VALERI, Auteur ; Stefano VICARI, Auteur ; Handan Ozek ERKURAN, Auteur ; Ferhat YAYLACI, Auteur ; Lilia ALBORES-GALLO, Auteur ; Gabriel GATICA-BAHAMONDE, Auteur ; Maia GABUNIA, Auteur ; Medea ZIRAKASHVILI, Auteur ; Tony CHARMAN, Auteur ; Sayyed Ali SAMADI, Auteur ; Teck-Hock TOH, Auteur ; Windham GAYLE, Auteur ; Laura BRENNAN, Auteur ; Tatjana ZORCEC, Auteur ; Alejandra AUZA, Auteur ; Maretha DE JONGE, Auteur ; Noordeen SHOQIRAT, Auteur ; Rajna KNEZ, Auteur Article en page(s) : 101984 Langues : Anglais (eng) Mots-clés : Toddlers  Autism  Screening  Culture  Equivalence Index. décimale : PER Périodiques Résumé : Background This study aimed to evaluate the endorsement rates of M-CHAT(-R) items by parents/caregivers of toddlers with autism spectrum disorder (ASD) synthesizing data from ten countries: Albania, Chile, Georgia, Macedonia, Malaysia, Mexico, Serbia, Turkey, United Kingdom, and the United States of America. Method Data were aggregated for toddlers aged 14?36 months who participated in previous studies or completed clinical screening. An item with < 30% of endorsements was classified as low endorsement, an item falling within the range of 30?60% as moderate endorsement, and an item with > 60% as high endorsement. Results All items had a low endorsement rate in at least one country and moderate to high in others. Of 20 items, 14 had a moderate to high endorsement rate in seven to nine countries. Of particular relevance are items with moderate to high endorsement rates in all countries excluding Malaysia, such as points to get help, points to show, brings things to show, follows a point, follows your gaze, and understands what is said. On the other hand, makes eye contact, responds to name, hearing concerns, and reciprocal smile were interpreted differently across the countries. Conclusions This study showed differences in parent/caregiver responding to M-CHAT(-R) items across ten countries, which may indicate cross-country variations in the recognition and evaluation of autistic symptoms in toddlers. Items related to joint attention, social engagement, and language comprehension were reported in a similar manner across countries and could be interpreted as universal autistic symptoms in toddlers. En ligne : https://doi.org/10.1016/j.rasd.2022.101984 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] Cross-cultural similarities and differences in reporting autistic symptoms in toddlers: A study synthesizing M-CHAT(-R) data from ten countries [Texte imprimé et/ou numérique] / Dejan STEVANOVIC, Auteur ; Diana L. ROBINS, Auteur ; Floriana COSTANZO, Auteur ; Elisa FUCA, Auteur ; Giovanni VALERI, Auteur ; Stefano VICARI, Auteur ; Handan Ozek ERKURAN, Auteur ; Ferhat YAYLACI, Auteur ; Lilia ALBORES-GALLO, Auteur ; Gabriel GATICA-BAHAMONDE, Auteur ; Maia GABUNIA, Auteur ; Medea ZIRAKASHVILI, Auteur ; Tony CHARMAN, Auteur ; Sayyed Ali SAMADI, Auteur ; Teck-Hock TOH, Auteur ; Windham GAYLE, Auteur ; Laura BRENNAN, Auteur ; Tatjana ZORCEC, Auteur ; Alejandra AUZA, Auteur ; Maretha DE JONGE, Auteur ; Noordeen SHOQIRAT, Auteur ; Rajna KNEZ, Auteur . - 101984. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 95 (July 2022) . - 101984 Mots-clés : Toddlers  Autism  Screening  Culture  Equivalence Index. décimale : PER Périodiques Résumé : Background This study aimed to evaluate the endorsement rates of M-CHAT(-R) items by parents/caregivers of toddlers with autism spectrum disorder (ASD) synthesizing data from ten countries: Albania, Chile, Georgia, Macedonia, Malaysia, Mexico, Serbia, Turkey, United Kingdom, and the United States of America. Method Data were aggregated for toddlers aged 14?36 months who participated in previous studies or completed clinical screening. An item with < 30% of endorsements was classified as low endorsement, an item falling within the range of 30?60% as moderate endorsement, and an item with > 60% as high endorsement. Results All items had a low endorsement rate in at least one country and moderate to high in others. Of 20 items, 14 had a moderate to high endorsement rate in seven to nine countries. Of particular relevance are items with moderate to high endorsement rates in all countries excluding Malaysia, such as points to get help, points to show, brings things to show, follows a point, follows your gaze, and understands what is said. On the other hand, makes eye contact, responds to name, hearing concerns, and reciprocal smile were interpreted differently across the countries. Conclusions This study showed differences in parent/caregiver responding to M-CHAT(-R) items across ten countries, which may indicate cross-country variations in the recognition and evaluation of autistic symptoms in toddlers. Items related to joint attention, social engagement, and language comprehension were reported in a similar manner across countries and could be interpreted as universal autistic symptoms in toddlers. En ligne : https://doi.org/10.1016/j.rasd.2022.101984 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

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