Atypical Semantic Fluency and Recall in Children and Adolescents with Autism Spectrum Disorders Associated with Autism Symptoms and Adaptive Functioning / Malene FOLDAGER in Journal of Autism and Developmental Disorders, 53-11 (November 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-11 (November 2023) . - p.4280-4292 Titre : Atypical Semantic Fluency and Recall in Children and Adolescents with Autism Spectrum Disorders Associated with Autism Symptoms and Adaptive Functioning Type de document : Texte imprimé et/ou numérique Auteurs : Malene FOLDAGER, Auteur ; Martin VESTERGAARD, Auteur ; Jonathan LASSEN, Auteur ; Lea S. PETERSEN, Auteur ; Bob ORANJE, Auteur ; Bodil AGGERNAES, Auteur ; Erik SIMONSEN, Auteur Article en page(s) : p.4280-4292 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : It is unclear whether children with autism spectrum disorders have atypical semantic fluency and lower memory for the semantics of words. Therefore, we examined semantic typicality, fluency and recall for the categories of fruits and animals in 60 children with autism aged 7-15 years (boys: 48/girls: 12) compared to 60 typically developing controls. Relative to controls, the autism group had reduced animal fluency, fruit typicality and recall for fruits. Notably, these measures were associated with more autistic-like symptoms and/or lower adaptive functioning across the autism and control groups. In conclusion, atypical semantics of fruits in the autism group may reflect development of idiosyncratic semantic networks while their lower semantic fluency and recall suggest impaired executive language functions. En ligne : https://doi.org/10.1007/s10803-022-05677-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512 [article] Atypical Semantic Fluency and Recall in Children and Adolescents with Autism Spectrum Disorders Associated with Autism Symptoms and Adaptive Functioning [Texte imprimé et/ou numérique] / Malene FOLDAGER, Auteur ; Martin VESTERGAARD, Auteur ; Jonathan LASSEN, Auteur ; Lea S. PETERSEN, Auteur ; Bob ORANJE, Auteur ; Bodil AGGERNAES, Auteur ; Erik SIMONSEN, Auteur . - p.4280-4292. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-11 (November 2023) . - p.4280-4292 Index. décimale : PER Périodiques Résumé : It is unclear whether children with autism spectrum disorders have atypical semantic fluency and lower memory for the semantics of words. Therefore, we examined semantic typicality, fluency and recall for the categories of fruits and animals in 60 children with autism aged 7-15 years (boys: 48/girls: 12) compared to 60 typically developing controls. Relative to controls, the autism group had reduced animal fluency, fruit typicality and recall for fruits. Notably, these measures were associated with more autistic-like symptoms and/or lower adaptive functioning across the autism and control groups. In conclusion, atypical semantics of fruits in the autism group may reflect development of idiosyncratic semantic networks while their lower semantic fluency and recall suggest impaired executive language functions. En ligne : https://doi.org/10.1007/s10803-022-05677-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512

Psychopathological symptoms associated with psychosocial functioning in children and adolescents with autism spectrum disorders and their typically developing peers / Jonathan LASSEN in Research in Autism Spectrum Disorders, 98 (October 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 98 (October 2022) . - 102040 Titre : Psychopathological symptoms associated with psychosocial functioning in children and adolescents with autism spectrum disorders and their typically developing peers Type de document : Texte imprimé et/ou numérique Auteurs : Jonathan LASSEN, Auteur ; Bodil AGGERNAES, Auteur ; Malene FOLDAGER, Auteur ; Jesper PEDERSEN, Auteur ; Bob ORANJE, Auteur ; Troels W. KJAER, Auteur ; Sidse ARNFRED, Auteur ; Martin VESTERGAARD, Auteur Article en page(s) : 102040 Langues : Anglais (eng) Mots-clés : ASD  Autism  School attendance  Adaptive behavior  Special education  Internalizing Index. décimale : PER Périodiques Résumé : Children and adolescents with autism have increased prevalence of psychosocial disabilities. Studies in autism indicate that key psychosocial factors including adaptive functioning, school absence, special needs education, frequency of peer socialization and participation in organized leisure activities may differ in their relationship with autistic, internalizing and externalizing symptoms, but the findings are so far mixed. Therefore, we examined if these measures of psychosocial functioning displayed specific associations with autistic, internalizing and/or externalizing symptoms in 61 children with autism aged 7-14 years compared to 61 typically developing controls. Multiple linear regression analyses across all participants showed that lower adaptive functioning, frequency of peer socialization and participation in leisure activities were driven by more social communication problems and not internalizing, externalizing or autistic-like symptoms including rigidity, stereotypy and sensory sensitivity. Notably, increased school absence was specifically driven by more internalizing symptoms and not autistic or externalizing symptoms. These associations were observed across all participants, both children with autism and their typically developing peers, and therefore appear to be dimensional and general in nature. Within the autism group, children who received special needs education displayed fewer social communication problems compared to those who attended regular education, while a developmental history of social interaction problems was related to lower adaptive functioning. Our findings suggest that social communication problems are more critical for psychosocial functioning than other autistic-like behaviors, internalizing or externalizing symptoms but that efforts to reduce school absence specifically need to target internalizing symptoms and not autistic-like or externalizing symptoms. En ligne : https://doi.org/10.1016/j.rasd.2022.102040 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Psychopathological symptoms associated with psychosocial functioning in children and adolescents with autism spectrum disorders and their typically developing peers [Texte imprimé et/ou numérique] / Jonathan LASSEN, Auteur ; Bodil AGGERNAES, Auteur ; Malene FOLDAGER, Auteur ; Jesper PEDERSEN, Auteur ; Bob ORANJE, Auteur ; Troels W. KJAER, Auteur ; Sidse ARNFRED, Auteur ; Martin VESTERGAARD, Auteur . - 102040. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 98 (October 2022) . - 102040 Mots-clés : ASD  Autism  School attendance  Adaptive behavior  Special education  Internalizing Index. décimale : PER Périodiques Résumé : Children and adolescents with autism have increased prevalence of psychosocial disabilities. Studies in autism indicate that key psychosocial factors including adaptive functioning, school absence, special needs education, frequency of peer socialization and participation in organized leisure activities may differ in their relationship with autistic, internalizing and externalizing symptoms, but the findings are so far mixed. Therefore, we examined if these measures of psychosocial functioning displayed specific associations with autistic, internalizing and/or externalizing symptoms in 61 children with autism aged 7-14 years compared to 61 typically developing controls. Multiple linear regression analyses across all participants showed that lower adaptive functioning, frequency of peer socialization and participation in leisure activities were driven by more social communication problems and not internalizing, externalizing or autistic-like symptoms including rigidity, stereotypy and sensory sensitivity. Notably, increased school absence was specifically driven by more internalizing symptoms and not autistic or externalizing symptoms. These associations were observed across all participants, both children with autism and their typically developing peers, and therefore appear to be dimensional and general in nature. Within the autism group, children who received special needs education displayed fewer social communication problems compared to those who attended regular education, while a developmental history of social interaction problems was related to lower adaptive functioning. Our findings suggest that social communication problems are more critical for psychosocial functioning than other autistic-like behaviors, internalizing or externalizing symptoms but that efforts to reduce school absence specifically need to target internalizing symptoms and not autistic-like or externalizing symptoms. En ligne : https://doi.org/10.1016/j.rasd.2022.102040 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

Reduced mismatch negativity in children and adolescents with autism spectrum disorder is associated with their impaired adaptive functioning / Jonathan LASSEN in Autism Research, 15-8 (August 2022)  

Public ISBD [article]  inAutism Research > 15-8 (August 2022) . - p.1469-1481 Titre : Reduced mismatch negativity in children and adolescents with autism spectrum disorder is associated with their impaired adaptive functioning Type de document : Texte imprimé et/ou numérique Auteurs : Jonathan LASSEN, Auteur ; Bob ORANJE, Auteur ; Martin VESTERGAARD, Auteur ; Malene FOLDAGER, Auteur ; Troels W. KJAER, Auteur ; Sidse ARNFRED, Auteur ; Bodil AGGERNAES, Auteur Article en page(s) : p.1469-1481 Langues : Anglais (eng) Mots-clés : Acoustic Stimulation/methods  Adolescent  Autism Spectrum Disorder/complications  Autistic Disorder  Brain  Child  Electroencephalography/methods  Humans  Asd  Eeg  adaptive behavior  autism  mismatch negativity Index. décimale : PER Périodiques Résumé : Children and adolescents on the autism spectrum display sensory disturbances, rigid and repetitive behavior, social communication problems and a high prevalence of impaired adaptive functioning. Autism is associated with slowed behavioral and neural habituation to repeated sensory input and decreased responses to sensory deviations. Mismatch negativity (MMN) reflects a pre-attentive difference in the neural response to sensory deviations relative to regularities and studies overall suggest that children and adolescents with autism tend to have smaller MMN. However, it remains unclear whether reduced MMN in autism is coupled to severity of specific autistic symptoms or more generally to lower level of adaptive functioning. To address these questions, the present study used electroencephalography (EEG) to assess whether auditory MMN in 59 children and adolescents with autism aged 7-14years compared to 59 typically developing children and adolescents were related to specific autistic symptoms or level in adaptive functioning. As hypothesized, the autism group had a lower MMN amplitude than controls. Smaller MMN amplitudes were specifically associated with lower adaptive functioning in the autistic subjects but not in controls while no apparent relationships were observed with autistic-like social interaction and communication problems, atypical language, rigidity, stereotypy or sensory sensitivity symptoms. Our findings indicate that a blunted response to changes in sensory input may underlie or contribute to the generalized difficulties with adapting to daily life circumstances seen in children and adolescents with autism. LAY SUMMARY: Children and adolescents on the autism spectrum have a high prevalence of impaired adaptive functioning. Neuroimaging studies have reported that children and adolescents with autism display attenuated brain activity when discriminating sensory input. However, it is unknown whether this attenuation is related to autistic symptoms and/or adaptive functioning. The present study used electroencephalogram (EEG) to show that attenuated brain response in discrimination of novel compared to repetitive sounds in children and adolescents with autism is related to their impaired adaptive functioning. En ligne : http://dx.doi.org/10.1002/aur.2738 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 [article] Reduced mismatch negativity in children and adolescents with autism spectrum disorder is associated with their impaired adaptive functioning [Texte imprimé et/ou numérique] / Jonathan LASSEN, Auteur ; Bob ORANJE, Auteur ; Martin VESTERGAARD, Auteur ; Malene FOLDAGER, Auteur ; Troels W. KJAER, Auteur ; Sidse ARNFRED, Auteur ; Bodil AGGERNAES, Auteur . - p.1469-1481. Langues : Anglais (eng) in Autism Research > 15-8 (August 2022) . - p.1469-1481 Mots-clés : Acoustic Stimulation/methods  Adolescent  Autism Spectrum Disorder/complications  Autistic Disorder  Brain  Child  Electroencephalography/methods  Humans  Asd  Eeg  adaptive behavior  autism  mismatch negativity Index. décimale : PER Périodiques Résumé : Children and adolescents on the autism spectrum display sensory disturbances, rigid and repetitive behavior, social communication problems and a high prevalence of impaired adaptive functioning. Autism is associated with slowed behavioral and neural habituation to repeated sensory input and decreased responses to sensory deviations. Mismatch negativity (MMN) reflects a pre-attentive difference in the neural response to sensory deviations relative to regularities and studies overall suggest that children and adolescents with autism tend to have smaller MMN. However, it remains unclear whether reduced MMN in autism is coupled to severity of specific autistic symptoms or more generally to lower level of adaptive functioning. To address these questions, the present study used electroencephalography (EEG) to assess whether auditory MMN in 59 children and adolescents with autism aged 7-14years compared to 59 typically developing children and adolescents were related to specific autistic symptoms or level in adaptive functioning. As hypothesized, the autism group had a lower MMN amplitude than controls. Smaller MMN amplitudes were specifically associated with lower adaptive functioning in the autistic subjects but not in controls while no apparent relationships were observed with autistic-like social interaction and communication problems, atypical language, rigidity, stereotypy or sensory sensitivity symptoms. Our findings indicate that a blunted response to changes in sensory input may underlie or contribute to the generalized difficulties with adapting to daily life circumstances seen in children and adolescents with autism. LAY SUMMARY: Children and adolescents on the autism spectrum have a high prevalence of impaired adaptive functioning. Neuroimaging studies have reported that children and adolescents with autism display attenuated brain activity when discriminating sensory input. However, it is unknown whether this attenuation is related to autistic symptoms and/or adaptive functioning. The present study used electroencephalogram (EEG) to show that attenuated brain response in discrimination of novel compared to repetitive sounds in children and adolescents with autism is related to their impaired adaptive functioning. En ligne : http://dx.doi.org/10.1002/aur.2738 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483

Reduced P300 amplitude in children and adolescents with autism is associated with slowed processing speed, executive difficulties, and social-communication problems / Jonathan LASSEN in Autism, 29-1 (January 2025)  

Public ISBD [article]  inAutism > 29-1 (January 2025) . - p.222-232 Titre : Reduced P300 amplitude in children and adolescents with autism is associated with slowed processing speed, executive difficulties, and social-communication problems Type de document : Texte imprimé et/ou numérique Auteurs : Jonathan LASSEN, Auteur ; Bob ORANJE, Auteur ; Martin VESTERGAARD, Auteur ; Malene FOLDAGER, Auteur ; Troels W KJÆR, Auteur ; Bodil AGGERNÆS, Auteur ; Sidse ARNFRED, Auteur Article en page(s) : p.222-232 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  autism  electroencephalography  executive functions  P300  selective attention  social-communication Index. décimale : PER Périodiques Résumé : Compared to their neurotypically developing peers, children and adolescents with autism spectrum disorders tend to have attenuated neural responses in the parietal lobe when attending sensory input, as reflected by a reduced P3b amplitude measured with electroencephalography. However, it is unknown whether a reduced P3b amplitude in autistic children and adolescents is associated with their autism traits, daily functioning, and/or cognitive functions. To address these questions, we assessed 57 children with autism aged 7-14?years and 57 typically developing children with electroencephalography using a binaural auditory oddball paradigm. Participants further underwent cognitive assessment, and parents reported on autistic traits, executive functioning, and adaptive functioning. As expected, children with autism had lower P3b amplitude compared to controls. Across all participants, a lower P3b amplitude was associated with more parent-reported social-communication problems and impairments in daily executive functioning. Children with autism had reduced visual processing speed, which was coupled to a lower P3b amplitude. In conclusion, we found attenuated P3b amplitude in children with autism performing an auditory selective attention task, which generalized to impaired cross-modal processing of visual input and an underlying impairment in allocating attentional resources critical for social and executive functioning.Lay abstractSelective attention to auditory input is reflected in the brain by an electric amplitude called the P3b amplitude, which is measured using electroencephalography. Previous research has shown that children and adolescents with autism have an attenuated P3b amplitude when they have to attend specific sounds while ignoring other sounds. However, it is unknown whether a reduced P3b amplitude in autistic children and adolescents is associated with their autism features, daily functioning and/or cognitive functions. This study aimed to examine these questions. Therefore, we assessed selective attention to auditory input in 57 children with autism aged 7-14?years and 57 neurotypically developing controls while measuring their brain activity with electroencephalography. Participants further underwent cognitive assessment, and parents reported on autistic traits and daily functioning. As expected, children with autism had lower P3b amplitude compared to their neurotypical peers. Importantly, an attenuated P3b amplitude was associated with more parent-reported social-communication problems and difficulties with daily functioning. Children with autism further had reduced processing speed of visual input, which also was coupled to a lower P3b amplitude. In conclusion, we found attenuated P3b amplitude in children with autism performing an auditory selective attention task, which was related to difficulties with processing visual input and allocating attentional resources critical for social and daily functioning. The results suggest that autistic children are more vulnerable to being disturbed when the environment is filled with conflicting sensory input. En ligne : https://dx.doi.org/10.1177/13623613241271950 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544 [article] Reduced P300 amplitude in children and adolescents with autism is associated with slowed processing speed, executive difficulties, and social-communication problems [Texte imprimé et/ou numérique] / Jonathan LASSEN, Auteur ; Bob ORANJE, Auteur ; Martin VESTERGAARD, Auteur ; Malene FOLDAGER, Auteur ; Troels W KJÆR, Auteur ; Bodil AGGERNÆS, Auteur ; Sidse ARNFRED, Auteur . - p.222-232. Langues : Anglais (eng) in Autism > 29-1 (January 2025) . - p.222-232 Mots-clés : Autism spectrum disorder  autism  electroencephalography  executive functions  P300  selective attention  social-communication Index. décimale : PER Périodiques Résumé : Compared to their neurotypically developing peers, children and adolescents with autism spectrum disorders tend to have attenuated neural responses in the parietal lobe when attending sensory input, as reflected by a reduced P3b amplitude measured with electroencephalography. However, it is unknown whether a reduced P3b amplitude in autistic children and adolescents is associated with their autism traits, daily functioning, and/or cognitive functions. To address these questions, we assessed 57 children with autism aged 7-14?years and 57 typically developing children with electroencephalography using a binaural auditory oddball paradigm. Participants further underwent cognitive assessment, and parents reported on autistic traits, executive functioning, and adaptive functioning. As expected, children with autism had lower P3b amplitude compared to controls. Across all participants, a lower P3b amplitude was associated with more parent-reported social-communication problems and impairments in daily executive functioning. Children with autism had reduced visual processing speed, which was coupled to a lower P3b amplitude. In conclusion, we found attenuated P3b amplitude in children with autism performing an auditory selective attention task, which generalized to impaired cross-modal processing of visual input and an underlying impairment in allocating attentional resources critical for social and executive functioning.Lay abstractSelective attention to auditory input is reflected in the brain by an electric amplitude called the P3b amplitude, which is measured using electroencephalography. Previous research has shown that children and adolescents with autism have an attenuated P3b amplitude when they have to attend specific sounds while ignoring other sounds. However, it is unknown whether a reduced P3b amplitude in autistic children and adolescents is associated with their autism features, daily functioning and/or cognitive functions. This study aimed to examine these questions. Therefore, we assessed selective attention to auditory input in 57 children with autism aged 7-14?years and 57 neurotypically developing controls while measuring their brain activity with electroencephalography. Participants further underwent cognitive assessment, and parents reported on autistic traits and daily functioning. As expected, children with autism had lower P3b amplitude compared to their neurotypical peers. Importantly, an attenuated P3b amplitude was associated with more parent-reported social-communication problems and difficulties with daily functioning. Children with autism further had reduced processing speed of visual input, which also was coupled to a lower P3b amplitude. In conclusion, we found attenuated P3b amplitude in children with autism performing an auditory selective attention task, which was related to difficulties with processing visual input and allocating attentional resources critical for social and daily functioning. The results suggest that autistic children are more vulnerable to being disturbed when the environment is filled with conflicting sensory input. En ligne : https://dx.doi.org/10.1177/13623613241271950 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544

---

1 (1 - 4 / 4)