ADHD and autism symptoms in youth: a network analysis / Luis C. FARHAT in Journal of Child Psychology and Psychiatry, 63-2 (February 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-2 (February 2022) . - p.143-151 Titre : ADHD and autism symptoms in youth: a network analysis Type de document : texte imprimé Auteurs : Luis C. FARHAT, Auteur ; Helena BRENTANI, Auteur ; Victor Hugo Calegari DE TOLEDO, Auteur ; Elizabeth SHEPHARD, Auteur ; Paulo MATTOS, Auteur ; Simon BARON-COHEN, Auteur ; Anita THAPAR, Auteur ; Erasmo CASELLA, Auteur ; Guilherme V. POLANCZYK, Auteur Article en page(s) : p.143-151 Langues : Anglais (eng) Mots-clés : Attention-deficit hyperactivity disorder  autism spectrum disorder  comorbidity  network analysis  neurodevelopmental Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous research investigating the overlap between attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (henceforth, autism) symptoms in population samples have relied on latent variable modeling in which averaged scores representing dimensions were derived from observed symptoms. There are no studies evaluating how ADHD and autism symptoms interact at the level of individual symptom items. METHODS: We aimed to address this gap by performing a network analysis on data from a school survey of children aged 6-17 years old (N = 7,405). ADHD and autism symptoms were measured via parent-report on the Swanson, Nolan, Pelham-IV questionnaire and the Childhood Autism Spectrum test, respectively. RESULTS: A relatively low interconnectivity between ADHD and autism symptoms was found with only 10.06% of possible connections (edges) between one ADHD and one autism symptoms different than zero. Associations between ADHD and autism symptoms were significantly weaker than those between two symptoms pertaining to the same construct. Select ADHD symptoms, particularly those presenting in social contexts (e.g. 'talks excessively', 'does not wait turn'), showed moderate-to-strong associations with autism symptoms, but some were considered redundant to autism symptoms. CONCLUSIONS: The present findings indicate that individual ADHD and autism symptoms are largely segregated in accordance with diagnostic boundaries corresponding to these conditions in children and adolescents from the community. These findings could improve our clinical conceptualization of ADHD and autism and guide advancements in diagnosis and treatment. En ligne : http://dx.doi.org/10.1111/jcpp.13436 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] ADHD and autism symptoms in youth: a network analysis [texte imprimé] / Luis C. FARHAT, Auteur ; Helena BRENTANI, Auteur ; Victor Hugo Calegari DE TOLEDO, Auteur ; Elizabeth SHEPHARD, Auteur ; Paulo MATTOS, Auteur ; Simon BARON-COHEN, Auteur ; Anita THAPAR, Auteur ; Erasmo CASELLA, Auteur ; Guilherme V. POLANCZYK, Auteur . - p.143-151. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-2 (February 2022) . - p.143-151 Mots-clés : Attention-deficit hyperactivity disorder  autism spectrum disorder  comorbidity  network analysis  neurodevelopmental Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous research investigating the overlap between attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (henceforth, autism) symptoms in population samples have relied on latent variable modeling in which averaged scores representing dimensions were derived from observed symptoms. There are no studies evaluating how ADHD and autism symptoms interact at the level of individual symptom items. METHODS: We aimed to address this gap by performing a network analysis on data from a school survey of children aged 6-17 years old (N = 7,405). ADHD and autism symptoms were measured via parent-report on the Swanson, Nolan, Pelham-IV questionnaire and the Childhood Autism Spectrum test, respectively. RESULTS: A relatively low interconnectivity between ADHD and autism symptoms was found with only 10.06% of possible connections (edges) between one ADHD and one autism symptoms different than zero. Associations between ADHD and autism symptoms were significantly weaker than those between two symptoms pertaining to the same construct. Select ADHD symptoms, particularly those presenting in social contexts (e.g. 'talks excessively', 'does not wait turn'), showed moderate-to-strong associations with autism symptoms, but some were considered redundant to autism symptoms. CONCLUSIONS: The present findings indicate that individual ADHD and autism symptoms are largely segregated in accordance with diagnostic boundaries corresponding to these conditions in children and adolescents from the community. These findings could improve our clinical conceptualization of ADHD and autism and guide advancements in diagnosis and treatment. En ligne : http://dx.doi.org/10.1111/jcpp.13436 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

Commentary: Identifying individualized predictions of response in ADHD pharmacotherapy - a commentary on Rodrigues et al. (2020) / Luis C. FARHAT in Journal of Child Psychology and Psychiatry, 62-6 (June 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-6 (June 2021) . - p.701-703 Titre : Commentary: Identifying individualized predictions of response in ADHD pharmacotherapy - a commentary on Rodrigues et al. (2020) Type de document : texte imprimé Auteurs : Luis C. FARHAT, Auteur ; Michael H. BLOCH, Auteur Article en page(s) : p.701-703 Langues : Anglais (eng) Mots-clés : Atomoxetine Hydrochloride/pharmacology  Attention Deficit Disorder with Hyperactivity/drug therapy  Autism Spectrum Disorder/drug therapy  Child  Guanfacine/pharmacology  Humans  Methylphenidate/pharmacology Index. décimale : PER Périodiques Résumé : In this issue, Rodrigues et al. (2020) present a systematic review with meta-analyses that reports the efficacy of five treatments for children with attention-deficit hyperactivity disorder symptoms in the context of autism spectrum disorder - (a) methylphenidate; (b) atomoxetine; (c) guanfacine; (d) aripiprazole; and (e) risperidone. In this commentary, we highlight the contrast between the scarce evidence base of treatment for ADHD in the context of autism and other subpopulations, such as tic disorders and intellectual disability, and the extensive evidence base of treatment for ADHD in general. The commentary weighs about the conundrum clinicians face of whether to rely on the limited evidence base of treatment for ADHD in subpopulation, or to derive conclusions from the larger body of evidence of treatment for ADHD in general. The commentary also discusses potential avenues for future research to address this clinical problem. En ligne : http://dx.doi.org/10.1111/jcpp.13374 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] Commentary: Identifying individualized predictions of response in ADHD pharmacotherapy - a commentary on Rodrigues et al. (2020) [texte imprimé] / Luis C. FARHAT, Auteur ; Michael H. BLOCH, Auteur . - p.701-703. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-6 (June 2021) . - p.701-703 Mots-clés : Atomoxetine Hydrochloride/pharmacology  Attention Deficit Disorder with Hyperactivity/drug therapy  Autism Spectrum Disorder/drug therapy  Child  Guanfacine/pharmacology  Humans  Methylphenidate/pharmacology Index. décimale : PER Périodiques Résumé : In this issue, Rodrigues et al. (2020) present a systematic review with meta-analyses that reports the efficacy of five treatments for children with attention-deficit hyperactivity disorder symptoms in the context of autism spectrum disorder - (a) methylphenidate; (b) atomoxetine; (c) guanfacine; (d) aripiprazole; and (e) risperidone. In this commentary, we highlight the contrast between the scarce evidence base of treatment for ADHD in the context of autism and other subpopulations, such as tic disorders and intellectual disability, and the extensive evidence base of treatment for ADHD in general. The commentary weighs about the conundrum clinicians face of whether to rely on the limited evidence base of treatment for ADHD in subpopulation, or to derive conclusions from the larger body of evidence of treatment for ADHD in general. The commentary also discusses potential avenues for future research to address this clinical problem. En ligne : http://dx.doi.org/10.1111/jcpp.13374 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

Editorial: Are we too high on medicinal cannabis in child psychiatry? Examining the evidence in Tourette syndrome / Loren S. HARDEMAN in Journal of Child Psychology and Psychiatry, 66-12 (December 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-12 (December 2025) . - p.1781-1783 Titre : Editorial: Are we too high on medicinal cannabis in child psychiatry? Examining the evidence in Tourette syndrome Type de document : texte imprimé Auteurs : Loren S. HARDEMAN, Auteur ; Luis C. FARHAT, Auteur ; Julian KOENIG, Auteur ; Michael H. BLOCH, Auteur Article en page(s) : p.1781-1783 Langues : Anglais (eng) Mots-clés : Tourette syndrome  pharmacotherapy  neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : There has been renewed interest in elucidating the role of the endocannabinoid system on both brain development and psychological phenomena across the lifespan. In parallel to these efforts, the use of cannabis-related drugs for the treatment of psychiatric disorders in the community has increased considerably over the past several years. In an excellent research review article in JCPP, Tansey et al. provide a comprehensive overview of what the field of developmental psychopathology has learned about the endocannabinoid system. The purpose of this Editorial is to build upon the discussion around the current state of evidence for medicinal cannabis for psychiatric disorders, using Tourette syndrome and chronic tic disorders as an illustrative example. En ligne : https://doi.org/10.1111/jcpp.70075 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572 [article] Editorial: Are we too high on medicinal cannabis in child psychiatry? Examining the evidence in Tourette syndrome [texte imprimé] / Loren S. HARDEMAN, Auteur ; Luis C. FARHAT, Auteur ; Julian KOENIG, Auteur ; Michael H. BLOCH, Auteur . - p.1781-1783. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-12 (December 2025) . - p.1781-1783 Mots-clés : Tourette syndrome  pharmacotherapy  neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : There has been renewed interest in elucidating the role of the endocannabinoid system on both brain development and psychological phenomena across the lifespan. In parallel to these efforts, the use of cannabis-related drugs for the treatment of psychiatric disorders in the community has increased considerably over the past several years. In an excellent research review article in JCPP, Tansey et al. provide a comprehensive overview of what the field of developmental psychopathology has learned about the endocannabinoid system. The purpose of this Editorial is to build upon the discussion around the current state of evidence for medicinal cannabis for psychiatric disorders, using Tourette syndrome and chronic tic disorders as an illustrative example. En ligne : https://doi.org/10.1111/jcpp.70075 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572

Editorial: From adolescence into young adulthood - the importance of a longitudinal perspective across development in child and adolescent mental health / Julian KOENIG in Journal of Child Psychology and Psychiatry, 66-1 (January 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-1 (January 2025) . - p.1-3 Titre : Editorial: From adolescence into young adulthood - the importance of a longitudinal perspective across development in child and adolescent mental health Type de document : texte imprimé Auteurs : Julian KOENIG, Auteur ; Luis C. FARHAT, Auteur ; Michael H. BLOCH, Auteur Article en page(s) : p.1-3 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The transition from adolescence into adulthood is a pivotal phase in a person's life, marking a period of significant social, psychological, and biological changes that can profoundly impact an individual's well-being and developmental trajectory. During this period, adolescents and young adults face increasing environmental demands from academic or occupational responsibilities and social interactions, including the pursuit of romantic partners. These changes are inherently related to stress, which is essential for adolescents and young adults to develop their personality and form an identity. Throughout adolescence into young adulthood, the brain undergoes maturational changes as part of the normal development, and it is possible that deviations from the expected developmental trajectories may contribute to the onset of psychiatric disorders in this age group. This editorial highlights recent work published in the Journal of Child Psychology and Psychiatry that examines important aspects of this developmental period. En ligne : https://dx.doi.org/10.1111/jcpp.14094 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544 [article] Editorial: From adolescence into young adulthood - the importance of a longitudinal perspective across development in child and adolescent mental health [texte imprimé] / Julian KOENIG, Auteur ; Luis C. FARHAT, Auteur ; Michael H. BLOCH, Auteur . - p.1-3. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-1 (January 2025) . - p.1-3 Index. décimale : PER Périodiques Résumé : The transition from adolescence into adulthood is a pivotal phase in a person's life, marking a period of significant social, psychological, and biological changes that can profoundly impact an individual's well-being and developmental trajectory. During this period, adolescents and young adults face increasing environmental demands from academic or occupational responsibilities and social interactions, including the pursuit of romantic partners. These changes are inherently related to stress, which is essential for adolescents and young adults to develop their personality and form an identity. Throughout adolescence into young adulthood, the brain undergoes maturational changes as part of the normal development, and it is possible that deviations from the expected developmental trajectories may contribute to the onset of psychiatric disorders in this age group. This editorial highlights recent work published in the Journal of Child Psychology and Psychiatry that examines important aspects of this developmental period. En ligne : https://dx.doi.org/10.1111/jcpp.14094 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544

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