Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Autism Research . 10-10Paru le : 01/10/2017 |
[n° ou bulletin]
[n° ou bulletin]
10-10 - October 2017 [Texte imprimé et/ou numérique] . - 2017. Langues : Anglais (eng)
|
Exemplaires (1)
Code-barres | Cote | Support | Localisation | Section | Disponibilité |
---|---|---|---|---|---|
PER0001594 | PER ARE | Périodique | Centre d'Information et de Documentation du CRA Rhône-Alpes | PER - Périodiques | Exclu du prêt |
Dépouillements
Ajouter le résultat dans votre panier
[article]
Titre : Issue Information Type de document : Texte imprimé et/ou numérique Article en page(s) : p.1579-1583 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1703 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1579-1583[article] Issue Information [Texte imprimé et/ou numérique] . - p.1579-1583.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1579-1583
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1703 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Behavioral abnormalities in the Fmr1-KO2 mouse model of fragile X syndrome: The relevance of early life phases / Julie GAUDISSARD in Autism Research, 10-10 (October 2017)
[article]
Titre : Behavioral abnormalities in the Fmr1-KO2 mouse model of fragile X syndrome: The relevance of early life phases Type de document : Texte imprimé et/ou numérique Auteurs : Julie GAUDISSARD, Auteur ; Melanie GINGER, Auteur ; Marika PREMOLI, Auteur ; Maurizio MEMO, Auteur ; Andreas FRICK, Auteur ; Susanna PIETROPAOLO, Auteur Article en page(s) : p.1584-1596 Langues : Anglais (eng) Mots-clés : Fragile X syndrome autism development adolescence social interaction anxiety cognition Index. décimale : PER Périodiques Résumé : Fragile X syndrome (FXS) is a developmental disorder caused by a mutation in the X-linked FMR1 gene, coding for the FMRP protein which is largely involved in synaptic function. FXS patients present several behavioral abnormalities, including hyperactivity, anxiety, sensory hyper-responsiveness, and cognitive deficits. Autistic symptoms, e.g., altered social interaction and communication, are also often observed: FXS is indeed the most common monogenic cause of autism. Mouse models of FXS are therefore of great interest for research on both FXS and autistic pathologies. The Fmr1-KO2 mouse line is the most recent FXS model, widely used for brain studies; surprisingly, little is known about the face validity of this model, i.e., its FXS-like behavioral phenotype. Furthermore, no data are available for the age-related expression of the pathological phenotypes in this mouse line, a critical issue for modelling neurodevelopmental disorders. Here we performed an extensive behavioral characterization of the KO2 model at infancy, adolescent and adult ages. Hyperactivity, altered emotionality, sensory hyper-responsiveness and memory deficits were already present in KO mice at adolescence and remained evident at adulthood. Alterations in social behaviors were instead observed only in young KO animals: during the first 2 weeks of life, KOs emitted longer ultrasonic vocalizations compared to their WT littermates and as adolescents they displayed more aggressive behaviors towards a conspecific. These results strongly support the face validity of the KO2 mouse as a model for FXS, at the same time demonstrating that its ability to recapitulate social autistic-relevant phenotypes depends on early testing ages. Autism Res 2017, 10: 1584–1596. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1584-1596[article] Behavioral abnormalities in the Fmr1-KO2 mouse model of fragile X syndrome: The relevance of early life phases [Texte imprimé et/ou numérique] / Julie GAUDISSARD, Auteur ; Melanie GINGER, Auteur ; Marika PREMOLI, Auteur ; Maurizio MEMO, Auteur ; Andreas FRICK, Auteur ; Susanna PIETROPAOLO, Auteur . - p.1584-1596.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1584-1596
Mots-clés : Fragile X syndrome autism development adolescence social interaction anxiety cognition Index. décimale : PER Périodiques Résumé : Fragile X syndrome (FXS) is a developmental disorder caused by a mutation in the X-linked FMR1 gene, coding for the FMRP protein which is largely involved in synaptic function. FXS patients present several behavioral abnormalities, including hyperactivity, anxiety, sensory hyper-responsiveness, and cognitive deficits. Autistic symptoms, e.g., altered social interaction and communication, are also often observed: FXS is indeed the most common monogenic cause of autism. Mouse models of FXS are therefore of great interest for research on both FXS and autistic pathologies. The Fmr1-KO2 mouse line is the most recent FXS model, widely used for brain studies; surprisingly, little is known about the face validity of this model, i.e., its FXS-like behavioral phenotype. Furthermore, no data are available for the age-related expression of the pathological phenotypes in this mouse line, a critical issue for modelling neurodevelopmental disorders. Here we performed an extensive behavioral characterization of the KO2 model at infancy, adolescent and adult ages. Hyperactivity, altered emotionality, sensory hyper-responsiveness and memory deficits were already present in KO mice at adolescence and remained evident at adulthood. Alterations in social behaviors were instead observed only in young KO animals: during the first 2 weeks of life, KOs emitted longer ultrasonic vocalizations compared to their WT littermates and as adolescents they displayed more aggressive behaviors towards a conspecific. These results strongly support the face validity of the KO2 mouse as a model for FXS, at the same time demonstrating that its ability to recapitulate social autistic-relevant phenotypes depends on early testing ages. Autism Res 2017, 10: 1584–1596. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Prevalence of autism spectrum disorder and autistic symptoms in a school-based cohort of children in Kolkata, India / Alokananda RUDRA in Autism Research, 10-10 (October 2017)
[article]
Titre : Prevalence of autism spectrum disorder and autistic symptoms in a school-based cohort of children in Kolkata, India Type de document : Texte imprimé et/ou numérique Auteurs : Alokananda RUDRA, Auteur ; Matthew K. BELMONTE, Auteur ; Parmeet Kaur SONI, Auteur ; Saoni BANERJEE, Auteur ; Shaneel MUKERJI, Auteur ; Bhismadev CHAKRABARTI, Auteur Article en page(s) : p.1597-1605 Langues : Anglais (eng) Mots-clés : low and middle income countries autism children epidemiology prevalence assessment Index. décimale : PER Périodiques Résumé : Despite housing ?18% of the world's population, India does not yet have an estimate of prevalence of autism. This study was carried out to estimate the prevalence of autism in a selected population of school-children in India. N?=?11,849 children (mean age?=?5.9 [SD?=?1.3], 39.5% females) were selected from various school types from three boroughs in Kolkata, India. Parents/caregivers and teachers filled in the social and communication disorders checklist (SCDC). Children meeting cutoff on parent-reported SCDC were followed up with the social communication questionnaire (SCQ). SCQ-positive children were administered the autism diagnostic observation schedule (ADOS). Teacher report on SCDC was available on all 11,849 children. Parent-report SCDC scores were obtained for 5,947 children. Mean scores on teacher SCDC were significantly lower than parent SCDC. Out of 1,247 SCDC-positive children, 882 answered the SCQ, of whom 124 met the cutoff score of 15. Six of these children met criteria for autism, autism spectrum disorder (ASD), or broader autism spectrum on the ADOS. The weighted estimate of supra-threshold SCQ scores was 3.54% (CI: 2.88–4.3%). The weighted prevalence estimate of positive scores (for broader autism spectrum?+?ASD?+?autism) was 0.23% (0.07–0.46%). As ?20% children in this state are known to be out of the school system, and ASD prevalence is likely to be higher in this group, this estimate is likely to represent the lower-bound of the true prevalence. This study provides preliminary data on the prevalence of broader-spectrum autism and supra-threshold autistic traits in a population sample of school children in Eastern India. Autism Res 2017, 10: 1597–1605. ©2017 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research En ligne : http://dx.doi.org/10.1002/aur.1812 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1597-1605[article] Prevalence of autism spectrum disorder and autistic symptoms in a school-based cohort of children in Kolkata, India [Texte imprimé et/ou numérique] / Alokananda RUDRA, Auteur ; Matthew K. BELMONTE, Auteur ; Parmeet Kaur SONI, Auteur ; Saoni BANERJEE, Auteur ; Shaneel MUKERJI, Auteur ; Bhismadev CHAKRABARTI, Auteur . - p.1597-1605.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1597-1605
Mots-clés : low and middle income countries autism children epidemiology prevalence assessment Index. décimale : PER Périodiques Résumé : Despite housing ?18% of the world's population, India does not yet have an estimate of prevalence of autism. This study was carried out to estimate the prevalence of autism in a selected population of school-children in India. N?=?11,849 children (mean age?=?5.9 [SD?=?1.3], 39.5% females) were selected from various school types from three boroughs in Kolkata, India. Parents/caregivers and teachers filled in the social and communication disorders checklist (SCDC). Children meeting cutoff on parent-reported SCDC were followed up with the social communication questionnaire (SCQ). SCQ-positive children were administered the autism diagnostic observation schedule (ADOS). Teacher report on SCDC was available on all 11,849 children. Parent-report SCDC scores were obtained for 5,947 children. Mean scores on teacher SCDC were significantly lower than parent SCDC. Out of 1,247 SCDC-positive children, 882 answered the SCQ, of whom 124 met the cutoff score of 15. Six of these children met criteria for autism, autism spectrum disorder (ASD), or broader autism spectrum on the ADOS. The weighted estimate of supra-threshold SCQ scores was 3.54% (CI: 2.88–4.3%). The weighted prevalence estimate of positive scores (for broader autism spectrum?+?ASD?+?autism) was 0.23% (0.07–0.46%). As ?20% children in this state are known to be out of the school system, and ASD prevalence is likely to be higher in this group, this estimate is likely to represent the lower-bound of the true prevalence. This study provides preliminary data on the prevalence of broader-spectrum autism and supra-threshold autistic traits in a population sample of school children in Eastern India. Autism Res 2017, 10: 1597–1605. ©2017 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research En ligne : http://dx.doi.org/10.1002/aur.1812 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 White matter compromise in autism? Differentiating motion confounds from true differences in diffusion tensor imaging / Seraphina K. SOLDERS in Autism Research, 10-10 (October 2017)
[article]
Titre : White matter compromise in autism? Differentiating motion confounds from true differences in diffusion tensor imaging Type de document : Texte imprimé et/ou numérique Auteurs : Seraphina K. SOLDERS, Auteur ; Ruth A. CARPER, Auteur ; Ralph-Axel MULLER, Auteur Article en page(s) : p.1606-1620 Langues : Anglais (eng) Mots-clés : diffusion autism motion MRI white matter artifact Index. décimale : PER Périodiques Résumé : Common findings from diffusion tensor imaging (DTI) in autism spectrum disorder (ASD) include reduced fractional anisotropy (FA), and increased mean and radial diffusivity (MD, RD) of white matter tracts. However, findings may be confounded by head motion. We examined how group-level motion matching affects DTI comparisons between ASD and typically developing (TD) groups. We included 57 ASD and 50 TD participants, comparing three subsets at increasing levels of motion-matching stringency: full sample (FS); quality-controlled (QC); and quantitatively-matched (QM). Groups were compared on diffusivity measures using Tract-Based Spatial Statistics (TBSS) and probabilistic tractography. Two methods for estimating diffusivity were compared: dti-fit and restore. TBSS: In set FS, FA was reduced in the ASD compared to the TD group throughout the right hemisphere. This effect was less extensive in set QC and absent in set QM. However, effect sizes remained stable or increased with better quality-control in some regions. Tractography: In set QM, MD was significantly higher in ASD overall and RD was higher in bilateral ILF. Effects were more robust in QM than in FS or QC sets. Effect sizes in several tracts increased with stringent quality matching. Restore improved tensor estimates, with some increases in effect sizes, but did not fully compensate for reduced quality. Findings suggest that some previously reported DTI findings for ASD may have been confounded by motion. However, effects in the tightly matched subset indicate that tract-specific anomalies probably do exist in ASD. Our results highlight the need for careful quality-control and motion-matching. Autism Res 2017, 10: 1606–1620. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1606-1620[article] White matter compromise in autism? Differentiating motion confounds from true differences in diffusion tensor imaging [Texte imprimé et/ou numérique] / Seraphina K. SOLDERS, Auteur ; Ruth A. CARPER, Auteur ; Ralph-Axel MULLER, Auteur . - p.1606-1620.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1606-1620
Mots-clés : diffusion autism motion MRI white matter artifact Index. décimale : PER Périodiques Résumé : Common findings from diffusion tensor imaging (DTI) in autism spectrum disorder (ASD) include reduced fractional anisotropy (FA), and increased mean and radial diffusivity (MD, RD) of white matter tracts. However, findings may be confounded by head motion. We examined how group-level motion matching affects DTI comparisons between ASD and typically developing (TD) groups. We included 57 ASD and 50 TD participants, comparing three subsets at increasing levels of motion-matching stringency: full sample (FS); quality-controlled (QC); and quantitatively-matched (QM). Groups were compared on diffusivity measures using Tract-Based Spatial Statistics (TBSS) and probabilistic tractography. Two methods for estimating diffusivity were compared: dti-fit and restore. TBSS: In set FS, FA was reduced in the ASD compared to the TD group throughout the right hemisphere. This effect was less extensive in set QC and absent in set QM. However, effect sizes remained stable or increased with better quality-control in some regions. Tractography: In set QM, MD was significantly higher in ASD overall and RD was higher in bilateral ILF. Effects were more robust in QM than in FS or QC sets. Effect sizes in several tracts increased with stringent quality matching. Restore improved tensor estimates, with some increases in effect sizes, but did not fully compensate for reduced quality. Findings suggest that some previously reported DTI findings for ASD may have been confounded by motion. However, effects in the tightly matched subset indicate that tract-specific anomalies probably do exist in ASD. Our results highlight the need for careful quality-control and motion-matching. Autism Res 2017, 10: 1606–1620. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Empathic responding in preschool-aged children with familial risk for autism / Nicole M. MCDONALD in Autism Research, 10-10 (October 2017)
[article]
Titre : Empathic responding in preschool-aged children with familial risk for autism Type de document : Texte imprimé et/ou numérique Auteurs : Nicole M. MCDONALD, Auteur ; Haley G. MURPHY, Auteur ; Daniel S. MESSINGER, Auteur Article en page(s) : p.1621-1628 Langues : Anglais (eng) Mots-clés : empathic responding high-risk siblings autism spectrum disorder preschool age familial risk Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) show deficits in social and emotional reciprocity, which often include empathic responding. The younger siblings of children with ASD (high-risk siblings) are at elevated risk for ASD and for subclinical deficits in social-emotional functioning. Higher levels of empathy in high-risk siblings during the second and third years of life predict fewer ASD symptoms and likelihood of diagnosis. We conducted a multi-method investigation of empathic responding to an examiner's accident in 30 low-risk and 48 high-risk siblings with (n?=?12) and without ASD outcomes (n?=?36) at 4–6 years of age. Empathic responding was measured through behavioral observation and parent report. Prosocial behavior did not differ by ASD outcome. Children with ASD exhibited lower levels of personal distress than high-risk and low-risk siblings without ASD. Per parent report, high-risk siblings without ASD demonstrated higher levels of empathic responding than low-risk children, while the ASD group did not differ from children without ASD on this measure. Higher levels of observed empathic concern, but not prosocial behavior, were associated with lower Social Affect scores on the Autism Diagnostic Observation Schedule in high-risk children. Results suggest that ASD diagnosis and symptoms are associated with reduced emotional responsiveness to an adult's distress, but not associated with deficits in prosocial behavior at preschool age. Results do not support the idea that empathic responding is negatively impacted in a broader autism phenotype. Findings extend previous research by suggesting that empathy may be a protective factor in the social-emotional development of children with familial risk for ASD. Autism Res 2017, 10: 1621–1628. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1819 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1621-1628[article] Empathic responding in preschool-aged children with familial risk for autism [Texte imprimé et/ou numérique] / Nicole M. MCDONALD, Auteur ; Haley G. MURPHY, Auteur ; Daniel S. MESSINGER, Auteur . - p.1621-1628.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1621-1628
Mots-clés : empathic responding high-risk siblings autism spectrum disorder preschool age familial risk Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) show deficits in social and emotional reciprocity, which often include empathic responding. The younger siblings of children with ASD (high-risk siblings) are at elevated risk for ASD and for subclinical deficits in social-emotional functioning. Higher levels of empathy in high-risk siblings during the second and third years of life predict fewer ASD symptoms and likelihood of diagnosis. We conducted a multi-method investigation of empathic responding to an examiner's accident in 30 low-risk and 48 high-risk siblings with (n?=?12) and without ASD outcomes (n?=?36) at 4–6 years of age. Empathic responding was measured through behavioral observation and parent report. Prosocial behavior did not differ by ASD outcome. Children with ASD exhibited lower levels of personal distress than high-risk and low-risk siblings without ASD. Per parent report, high-risk siblings without ASD demonstrated higher levels of empathic responding than low-risk children, while the ASD group did not differ from children without ASD on this measure. Higher levels of observed empathic concern, but not prosocial behavior, were associated with lower Social Affect scores on the Autism Diagnostic Observation Schedule in high-risk children. Results suggest that ASD diagnosis and symptoms are associated with reduced emotional responsiveness to an adult's distress, but not associated with deficits in prosocial behavior at preschool age. Results do not support the idea that empathic responding is negatively impacted in a broader autism phenotype. Findings extend previous research by suggesting that empathy may be a protective factor in the social-emotional development of children with familial risk for ASD. Autism Res 2017, 10: 1621–1628. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1819 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 The measurement properties of the spence children's anxiety scale-parent version in a large international pooled sample of young people with autism spectrum disorder / Iliana MAGIATI in Autism Research, 10-10 (October 2017)
[article]
Titre : The measurement properties of the spence children's anxiety scale-parent version in a large international pooled sample of young people with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Iliana MAGIATI, Auteur ; Jian Wei LERH, Auteur ; Matthew J. HOLLOCKS, Auteur ; Mirko ULJAREVIC, Auteur ; Jacqui RODGERS, Auteur ; Helen MCCONACHIE, Auteur ; Ann OZSIVADJIAN, Auteur ; Mikle SOUTH, Auteur ; Amy VAN HECKE, Auteur ; Antonio HARDAN, Auteur ; Robin LIBOVE, Auteur ; Susan LEEKAM, Auteur ; Emily SIMONOFF, Auteur Article en page(s) : p.1629-1652 Langues : Anglais (eng) Mots-clés : autism spectrum disorder anxiety parent report measurement assessment reliability validity factor structure Index. décimale : PER Périodiques Résumé : Anxiety-related difficulties are common in ASD, but measuring anxiety reliably and validly is challenging. Despite an increasing number of studies, there is no clear agreement on which existing anxiety measure is more psychometrically sound and what is the factor structure of anxiety in ASD. The present study examined the internal consistency, convergent, divergent, and discriminant validity, as well as the factor structure of the Spence Children's Anxiety Scale-Parent Version (SCAS-P), in a large international pooled sample of 870 caregivers of youth with ASD from 12 studies in the United Kingdom, United States, and Singapore who completed the SCAS-P. Most were community recruited, while the majority had at least one measure of ASD symptomatology and either cognitive or adaptive functioning measures completed. Existing SCAS-P total scale and subscales had excellent internal consistency and good convergent, divergent and discriminant validity similar to or better than SCAS-P properties reported in typically developing children, except for the poorer internal consistency of the physical injury subscale. Confirmatory Factor Analysis (CFA) of the existing SCAS-P six-correlated factor structure was a poor fit for this pooled database. Principal component analysis using half of the pooled sample identified a 30-item five correlated factor structure, but a CFA of this PCA-derived structure in the second half of this pooled sample revealed a poor fit, although the PCA-derived SCAS-P scale and subscales had stronger validity and better internal consistency than the original SCAS-P. The study's limitations, the use of the SCAS-P to screen for DSM-derived anxiety problems in ASD and future research directions are discussed. Autism Res 2017, 10: 1629–1652. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1809 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1629-1652[article] The measurement properties of the spence children's anxiety scale-parent version in a large international pooled sample of young people with autism spectrum disorder [Texte imprimé et/ou numérique] / Iliana MAGIATI, Auteur ; Jian Wei LERH, Auteur ; Matthew J. HOLLOCKS, Auteur ; Mirko ULJAREVIC, Auteur ; Jacqui RODGERS, Auteur ; Helen MCCONACHIE, Auteur ; Ann OZSIVADJIAN, Auteur ; Mikle SOUTH, Auteur ; Amy VAN HECKE, Auteur ; Antonio HARDAN, Auteur ; Robin LIBOVE, Auteur ; Susan LEEKAM, Auteur ; Emily SIMONOFF, Auteur . - p.1629-1652.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1629-1652
Mots-clés : autism spectrum disorder anxiety parent report measurement assessment reliability validity factor structure Index. décimale : PER Périodiques Résumé : Anxiety-related difficulties are common in ASD, but measuring anxiety reliably and validly is challenging. Despite an increasing number of studies, there is no clear agreement on which existing anxiety measure is more psychometrically sound and what is the factor structure of anxiety in ASD. The present study examined the internal consistency, convergent, divergent, and discriminant validity, as well as the factor structure of the Spence Children's Anxiety Scale-Parent Version (SCAS-P), in a large international pooled sample of 870 caregivers of youth with ASD from 12 studies in the United Kingdom, United States, and Singapore who completed the SCAS-P. Most were community recruited, while the majority had at least one measure of ASD symptomatology and either cognitive or adaptive functioning measures completed. Existing SCAS-P total scale and subscales had excellent internal consistency and good convergent, divergent and discriminant validity similar to or better than SCAS-P properties reported in typically developing children, except for the poorer internal consistency of the physical injury subscale. Confirmatory Factor Analysis (CFA) of the existing SCAS-P six-correlated factor structure was a poor fit for this pooled database. Principal component analysis using half of the pooled sample identified a 30-item five correlated factor structure, but a CFA of this PCA-derived structure in the second half of this pooled sample revealed a poor fit, although the PCA-derived SCAS-P scale and subscales had stronger validity and better internal consistency than the original SCAS-P. The study's limitations, the use of the SCAS-P to screen for DSM-derived anxiety problems in ASD and future research directions are discussed. Autism Res 2017, 10: 1629–1652. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1809 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Sex differences in parent-reported executive functioning and adaptive behavior in children and young adults with autism spectrum disorder / Emily I. WHITE in Autism Research, 10-10 (October 2017)
[article]
Titre : Sex differences in parent-reported executive functioning and adaptive behavior in children and young adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Emily I. WHITE, Auteur ; Gregory L. WALLACE, Auteur ; Julia BASCOM, Auteur ; Anna Chelsea ARMOUR, Auteur ; Kelly REGISTER-BROWN, Auteur ; Haroon S. POPAL, Auteur ; Allison B. RATTO, Auteur ; Alex MARTIN, Auteur ; Lauren KENWORTHY, Auteur Article en page(s) : p.1653-1662 Langues : Anglais (eng) Mots-clés : autism spectrum sex differences executive function adaptive functioning Index. décimale : PER Périodiques Résumé : This study is the largest to date examining executive function and adaptive skills in females with autism spectrum disorder (ASD). Its primary aim was to utilize parent ratings of real-world executive functioning and adaptive behavior to better understand whether females with ASD differ from males with ASD in these areas of everyday functioning. We compared 79 females with ASD to 158 males with ASD (ages 7–18) who were statistically matched on age, IQ, and level of ADHD or ASD traits. All participants were assessed using the Behavior Rating Inventory of Executive Function (BRIEF) and a subset (56 females and 130 males) also received the Vineland Adaptive Behavior Scales (VABS). Females were rated by parents as having greater problems with executive function on the BRIEF. Parents also rated females as exhibiting more difficulties than males on the Daily Living Skills domain of the VABS. There was a correlation between increased global EF difficulty and decreased adaptive ability in both males and females. Our results indicate relative weaknesses for females compared to males diagnosed with ASD on executive function and daily living skills. These differences occur in the absence of sex differences in our sample in age, IQ, clinician ratings of core ASD symptomatology, parent ratings of ADHD symptoms, and parent-reported social and communication adaptive skills on the VABS. These findings indicate specific liabilities in real world EF and daily living skills for females with ASD and have important implications for targeting their treatments. Autism Res 2017, 10: 1653–1662. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1811 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1653-1662[article] Sex differences in parent-reported executive functioning and adaptive behavior in children and young adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Emily I. WHITE, Auteur ; Gregory L. WALLACE, Auteur ; Julia BASCOM, Auteur ; Anna Chelsea ARMOUR, Auteur ; Kelly REGISTER-BROWN, Auteur ; Haroon S. POPAL, Auteur ; Allison B. RATTO, Auteur ; Alex MARTIN, Auteur ; Lauren KENWORTHY, Auteur . - p.1653-1662.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1653-1662
Mots-clés : autism spectrum sex differences executive function adaptive functioning Index. décimale : PER Périodiques Résumé : This study is the largest to date examining executive function and adaptive skills in females with autism spectrum disorder (ASD). Its primary aim was to utilize parent ratings of real-world executive functioning and adaptive behavior to better understand whether females with ASD differ from males with ASD in these areas of everyday functioning. We compared 79 females with ASD to 158 males with ASD (ages 7–18) who were statistically matched on age, IQ, and level of ADHD or ASD traits. All participants were assessed using the Behavior Rating Inventory of Executive Function (BRIEF) and a subset (56 females and 130 males) also received the Vineland Adaptive Behavior Scales (VABS). Females were rated by parents as having greater problems with executive function on the BRIEF. Parents also rated females as exhibiting more difficulties than males on the Daily Living Skills domain of the VABS. There was a correlation between increased global EF difficulty and decreased adaptive ability in both males and females. Our results indicate relative weaknesses for females compared to males diagnosed with ASD on executive function and daily living skills. These differences occur in the absence of sex differences in our sample in age, IQ, clinician ratings of core ASD symptomatology, parent ratings of ADHD symptoms, and parent-reported social and communication adaptive skills on the VABS. These findings indicate specific liabilities in real world EF and daily living skills for females with ASD and have important implications for targeting their treatments. Autism Res 2017, 10: 1653–1662. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1811 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Validating the social responsiveness scale for adults with autism / Wai CHAN in Autism Research, 10-10 (October 2017)
[article]
Titre : Validating the social responsiveness scale for adults with autism Type de document : Texte imprimé et/ou numérique Auteurs : Wai CHAN, Auteur ; Leann E. SMITH, Auteur ; Jinkuk HONG, Auteur ; Jan S. GREENBERG, Auteur ; Marsha R. MAILICK, Auteur Article en page(s) : p.1663-1671 Langues : Anglais (eng) Mots-clés : Social Responsiveness Scale adults autism spectrum disorder validity Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale [SRS; Constantino & Gruber, 2005] is a widely-used measure of autism symptoms, but its application for the study of adults with autism spectrum disorders has not been fully evaluated. Using a factor structure consistent with The Diagnostic and Statistical Manual of Mental Disorders (5th ed., DSM-V) criteria for autism spectrum disorder [Frazier et al., 2014], the primary purpose of the current study was to establish the validity of the SRS with a sample of adults with autism spectrum disorder (N?=?237). Correlational analyses indicated that SRS factors were highly associated with autism symptoms and behavioral measures, indicating concurrent and predictive validity. Multiple regression results demonstrated that SRS factors were differentially related to measures specific to social or behavioral domains, indicating convergent and discriminant validity. Implications for future research are discussed. Autism Res 2017, 10: 1663–1671. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1813 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1663-1671[article] Validating the social responsiveness scale for adults with autism [Texte imprimé et/ou numérique] / Wai CHAN, Auteur ; Leann E. SMITH, Auteur ; Jinkuk HONG, Auteur ; Jan S. GREENBERG, Auteur ; Marsha R. MAILICK, Auteur . - p.1663-1671.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1663-1671
Mots-clés : Social Responsiveness Scale adults autism spectrum disorder validity Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale [SRS; Constantino & Gruber, 2005] is a widely-used measure of autism symptoms, but its application for the study of adults with autism spectrum disorders has not been fully evaluated. Using a factor structure consistent with The Diagnostic and Statistical Manual of Mental Disorders (5th ed., DSM-V) criteria for autism spectrum disorder [Frazier et al., 2014], the primary purpose of the current study was to establish the validity of the SRS with a sample of adults with autism spectrum disorder (N?=?237). Correlational analyses indicated that SRS factors were highly associated with autism symptoms and behavioral measures, indicating concurrent and predictive validity. Multiple regression results demonstrated that SRS factors were differentially related to measures specific to social or behavioral domains, indicating convergent and discriminant validity. Implications for future research are discussed. Autism Res 2017, 10: 1663–1671. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1813 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 The influence of parental concern on the utility of autism diagnostic instruments / Karoline Alexandra HAVDAHL in Autism Research, 10-10 (October 2017)
[article]
Titre : The influence of parental concern on the utility of autism diagnostic instruments Type de document : Texte imprimé et/ou numérique Auteurs : Karoline Alexandra HAVDAHL, Auteur ; Somer L. BISHOP, Auteur ; Pål SUREN, Auteur ; Anne-Siri ØYEN, Auteur ; Catherine LORD, Auteur ; Andrew PICKLES, Auteur ; Stephen VON TETZCHNER, Auteur ; Synnve SCHJØLBERG, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; W. Ian LIPKIN, Auteur ; Ezra SUSSER, Auteur ; Michaeline BRESNAHAN, Auteur ; Per MAGNUS, Auteur ; Nina STENBERG, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Camilla STOLTENBERG, Auteur Article en page(s) : p.1672-1686 Langues : Anglais (eng) Mots-clés : Autism Diagnostic Interview-Revised Autism Diagnostic Observation Schedule early diagnosis screening Index. décimale : PER Périodiques Résumé : The parental report-based Autism Diagnostic Interview-Revised (ADI-R) and the clinician observation-based Autism Diagnostic Observation Schedule (ADOS) have been validated primarily in U.S. clinics specialized in autism spectrum disorder (ASD), in which most children are referred by their parents because of ASD concern. This study assessed diagnostic agreement of the ADOS-2 and ADI-R toddler algorithms in a more broadly based sample of 679 toddlers (age 35–47 months) from the Norwegian Mother and Child Cohort. We also examined whether parental concern about ASD influenced instrument performance, comparing toddlers identified based on parental ASD concern (n?=?48) and parent-reported signs of developmental problems (screening) without a specific concern about ASD (n?=?400). The ADOS cutoffs showed consistently well-balanced sensitivity and specificity. The ADI-R cutoffs demonstrated good specificity, but reduced sensitivity, missing 43% of toddlers whose parents were not specifically concerned about ASD. The ADI-R and ADOS dimensional scores agreed well with clinical diagnoses (area under the curve???0.85), contributing additively to their prediction. On the ADI-R, different cutoffs were needed according to presence or absence of parental ASD concern, in order to achieve comparable balance of sensitivity and specificity. These results highlight the importance of taking parental concern about ASD into account when interpreting scores from parental report-based instruments such as the ADI-R. While the ADOS cutoffs performed consistently well, the additive contributions of ADI-R and ADOS scores to the prediction of ASD diagnosis underscore the value of combining instruments based on parent accounts and clinician observation in evaluation of ASD. Autism Res 2017, 10: 1672–1686. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1672-1686[article] The influence of parental concern on the utility of autism diagnostic instruments [Texte imprimé et/ou numérique] / Karoline Alexandra HAVDAHL, Auteur ; Somer L. BISHOP, Auteur ; Pål SUREN, Auteur ; Anne-Siri ØYEN, Auteur ; Catherine LORD, Auteur ; Andrew PICKLES, Auteur ; Stephen VON TETZCHNER, Auteur ; Synnve SCHJØLBERG, Auteur ; Nina GUNNES, Auteur ; Mady HORNIG, Auteur ; W. Ian LIPKIN, Auteur ; Ezra SUSSER, Auteur ; Michaeline BRESNAHAN, Auteur ; Per MAGNUS, Auteur ; Nina STENBERG, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Camilla STOLTENBERG, Auteur . - p.1672-1686.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1672-1686
Mots-clés : Autism Diagnostic Interview-Revised Autism Diagnostic Observation Schedule early diagnosis screening Index. décimale : PER Périodiques Résumé : The parental report-based Autism Diagnostic Interview-Revised (ADI-R) and the clinician observation-based Autism Diagnostic Observation Schedule (ADOS) have been validated primarily in U.S. clinics specialized in autism spectrum disorder (ASD), in which most children are referred by their parents because of ASD concern. This study assessed diagnostic agreement of the ADOS-2 and ADI-R toddler algorithms in a more broadly based sample of 679 toddlers (age 35–47 months) from the Norwegian Mother and Child Cohort. We also examined whether parental concern about ASD influenced instrument performance, comparing toddlers identified based on parental ASD concern (n?=?48) and parent-reported signs of developmental problems (screening) without a specific concern about ASD (n?=?400). The ADOS cutoffs showed consistently well-balanced sensitivity and specificity. The ADI-R cutoffs demonstrated good specificity, but reduced sensitivity, missing 43% of toddlers whose parents were not specifically concerned about ASD. The ADI-R and ADOS dimensional scores agreed well with clinical diagnoses (area under the curve???0.85), contributing additively to their prediction. On the ADI-R, different cutoffs were needed according to presence or absence of parental ASD concern, in order to achieve comparable balance of sensitivity and specificity. These results highlight the importance of taking parental concern about ASD into account when interpreting scores from parental report-based instruments such as the ADI-R. While the ADOS cutoffs performed consistently well, the additive contributions of ADI-R and ADOS scores to the prediction of ASD diagnosis underscore the value of combining instruments based on parent accounts and clinician observation in evaluation of ASD. Autism Res 2017, 10: 1672–1686. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Evaluating the importance of social motor synchronization and motor skill for understanding autism / Paula FITZPATRICK in Autism Research, 10-10 (October 2017)
[article]
Titre : Evaluating the importance of social motor synchronization and motor skill for understanding autism Type de document : Texte imprimé et/ou numérique Auteurs : Paula FITZPATRICK, Auteur ; Veronica ROMERO, Auteur ; Joseph L. AMARAL, Auteur ; Amie DUNCAN, Auteur ; Holly D. BARNARD, Auteur ; Michael J. RICHARDSON, Auteur ; R.C. SCHMIDT, Auteur Article en page(s) : p.1687-1699 Langues : Anglais (eng) Mots-clés : autism social synchronization dynamics social interaction motor skill Index. décimale : PER Périodiques Résumé : Impairments in social interaction and communicating with others are core features of autism spectrum disorder (ASD), but the specific processes underlying such social competence impairments are not well understood. An important key for increasing our understanding of ASD-specific social deficits may lie with the social motor synchronization that takes place when we implicitly coordinate our bodies with others. Here, we tested whether dynamical measures of synchronization differentiate children with ASD from controls and further explored the relationships between synchronization ability and motor control problems. We found (a) that children with ASD exhibited different and less stable patterns of social synchronization ability than controls; (b) children with ASD performed motor movements that were slower and more variable in both spacing and timing; and (c) some social synchronization that involved motor timing was related to motor ability but less rhythmic synchronization was not. These findings raise the possibility that objective dynamical measures of synchronization ability and motor skill could provide new insights into understanding the social deficits in ASD that could ultimately aid clinical diagnosis and prognosis. Autism Res 2017, 10: 1687–1699. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1808 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1687-1699[article] Evaluating the importance of social motor synchronization and motor skill for understanding autism [Texte imprimé et/ou numérique] / Paula FITZPATRICK, Auteur ; Veronica ROMERO, Auteur ; Joseph L. AMARAL, Auteur ; Amie DUNCAN, Auteur ; Holly D. BARNARD, Auteur ; Michael J. RICHARDSON, Auteur ; R.C. SCHMIDT, Auteur . - p.1687-1699.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1687-1699
Mots-clés : autism social synchronization dynamics social interaction motor skill Index. décimale : PER Périodiques Résumé : Impairments in social interaction and communicating with others are core features of autism spectrum disorder (ASD), but the specific processes underlying such social competence impairments are not well understood. An important key for increasing our understanding of ASD-specific social deficits may lie with the social motor synchronization that takes place when we implicitly coordinate our bodies with others. Here, we tested whether dynamical measures of synchronization differentiate children with ASD from controls and further explored the relationships between synchronization ability and motor control problems. We found (a) that children with ASD exhibited different and less stable patterns of social synchronization ability than controls; (b) children with ASD performed motor movements that were slower and more variable in both spacing and timing; and (c) some social synchronization that involved motor timing was related to motor ability but less rhythmic synchronization was not. These findings raise the possibility that objective dynamical measures of synchronization ability and motor skill could provide new insights into understanding the social deficits in ASD that could ultimately aid clinical diagnosis and prognosis. Autism Res 2017, 10: 1687–1699. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1808 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Cross-site randomized control trial of the Social ABCs caregiver-mediated intervention for toddlers with autism spectrum disorder / Jessica BRIAN in Autism Research, 10-10 (October 2017)
[article]
Titre : Cross-site randomized control trial of the Social ABCs caregiver-mediated intervention for toddlers with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur Article en page(s) : p.1700-1711 Langues : Anglais (eng) Mots-clés : Clinical trials developmental psychology intervention early language parent training positive affect social attention social orienting Index. décimale : PER Périodiques Résumé : To evaluate the efficacy of the Social ABCs parent-mediated intervention for toddlers with suspected or confirmed autism spectrum disorder (ASD), through a cross-site randomized control trial, sixty-three parent–toddler dyads (toddler age: 16–30 months) were randomized into treatment (Social ABCs) or control (service-as-usual) conditions. Video data were obtained at three key time-points: Baseline; Post-training (PT; week 12); and Follow-Up (week 24). Analyses included 62 dyads. Treatment allocation significantly accounted for PT gains, all favouring the Treatment group, in (1) child functional vocal responsiveness to parent prompts (R2?=?0.43, P?.001), (2) child vocal initiations (R2?=?0.28, P?.001), (3) parent smiling (R2?=?0.09, P?=?.017), and (4) fidelity of implementation (R2?=?0.71, P?.001). A trend was observed for increased social orienting (R2?=?0.06, P?=?0.054); gains in parent smiling significantly predicted increases in child smiling and social orienting. Parents in the treatment condition reported significant gains in self-efficacy following the intervention (P?=?0.009). No differential effects emerged for performance on standardized measures. The Social ABCs is a relatively low-resource, efficacious intervention, with potential to be a cost-effective means of intervening at the first signs of possible ASD. Autism Res 2017, 10: 1700–1711. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Clinical Trial Title: Social ABCs for Toddlers with Signs of Autism Spectrum Disorder: RCT of a Parent-Mediated Intervention http//ClinicalTrials.gov identifier: NCT02428452. En ligne : http://dx.doi.org/10.1002/aur.1818 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1700-1711[article] Cross-site randomized control trial of the Social ABCs caregiver-mediated intervention for toddlers with autism spectrum disorder [Texte imprimé et/ou numérique] / Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur . - p.1700-1711.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1700-1711
Mots-clés : Clinical trials developmental psychology intervention early language parent training positive affect social attention social orienting Index. décimale : PER Périodiques Résumé : To evaluate the efficacy of the Social ABCs parent-mediated intervention for toddlers with suspected or confirmed autism spectrum disorder (ASD), through a cross-site randomized control trial, sixty-three parent–toddler dyads (toddler age: 16–30 months) were randomized into treatment (Social ABCs) or control (service-as-usual) conditions. Video data were obtained at three key time-points: Baseline; Post-training (PT; week 12); and Follow-Up (week 24). Analyses included 62 dyads. Treatment allocation significantly accounted for PT gains, all favouring the Treatment group, in (1) child functional vocal responsiveness to parent prompts (R2?=?0.43, P?.001), (2) child vocal initiations (R2?=?0.28, P?.001), (3) parent smiling (R2?=?0.09, P?=?.017), and (4) fidelity of implementation (R2?=?0.71, P?.001). A trend was observed for increased social orienting (R2?=?0.06, P?=?0.054); gains in parent smiling significantly predicted increases in child smiling and social orienting. Parents in the treatment condition reported significant gains in self-efficacy following the intervention (P?=?0.009). No differential effects emerged for performance on standardized measures. The Social ABCs is a relatively low-resource, efficacious intervention, with potential to be a cost-effective means of intervening at the first signs of possible ASD. Autism Res 2017, 10: 1700–1711. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Clinical Trial Title: Social ABCs for Toddlers with Signs of Autism Spectrum Disorder: RCT of a Parent-Mediated Intervention http//ClinicalTrials.gov identifier: NCT02428452. En ligne : http://dx.doi.org/10.1002/aur.1818 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
[article]
Titre : Scientific Summaries for Families with ASD Type de document : Texte imprimé et/ou numérique Article en page(s) : p.1712-1715 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1878 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1712-1715[article] Scientific Summaries for Families with ASD [Texte imprimé et/ou numérique] . - p.1712-1715.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1712-1715
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1878 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
[article]
Titre : INSAR President's Message – October 2017 Type de document : Texte imprimé et/ou numérique Article en page(s) : p.1716-1716 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1876 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-10 (October 2017) . - p.1716-1716[article] INSAR President's Message – October 2017 [Texte imprimé et/ou numérique] . - p.1716-1716.
Langues : Anglais (eng)
in Autism Research > 10-10 (October 2017) . - p.1716-1716
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1876 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322