Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity / Bridget L. CALLAGHAN in Development and Psychopathology, 32-1 (February 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-1 (February 2020) . - p.309-328 Titre : Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity Type de document : Texte imprimé et/ou numérique Auteurs : Bridget L. CALLAGHAN, Auteur ; Andrea FIELDS, Auteur ; Dylan G. GEE, Auteur ; Laurel GABARD-DURNAM, Auteur ; Christina CALDERA, Auteur ; Kathryn L. HUMPHREYS, Auteur ; Bonnie GOFF, Auteur ; Jessica FLANNERY, Auteur ; Eva H. TELZER, Auteur ; Mor SHAPIRO, Auteur ; Nim TOTTENHAM, Auteur Article en page(s) : p.309-328 Langues : Anglais (eng) Mots-clés : anxiety  development  functional magnetic resonance imaging  gastrointestinal distress  microbiome Index. décimale : PER Périodiques Résumé : Gastrointestinal and mental disorders are highly comorbid, and animal models have shown that both can be caused by early adversity (e.g., parental deprivation). Interactions between the brain and bacteria that live within the gastrointestinal system (the microbiome) underlie adversity-gastrointestinal-anxiety interactions, but these links have not been investigated during human development. In this study, we utilized data from a population of 344 youth (3-18 years old) who were raised with their biological parents or were exposed to early adverse caregiving experiences (i.e., institutional or foster care followed by international adoption) to explore adversity-gastrointestinal-anxiety associations. In Study 1, we demonstrated that previous adverse care experiences were associated with increased incidence of gastrointestinal symptoms in youth. Gastrointestinal symptoms were also associated with concurrent and future anxiety (measured across 5 years), and those gastrointestinal symptoms mediated the adversity-anxiety association at Time 1. In a subsample of children who provided both stool samples and functional magnetic resonance imaging of the brain (Study 2, which was a "proof-of-principle"), adversity was associated with changes in diversity (both alpha and beta) of microbial communities, and bacteria levels (adversity-associated and adversity-independent) were correlated with prefrontal cortex activation to emotional faces. Implications of these data for supporting youth mental health are discussed. En ligne : http://dx.doi.org/10.1017/s0954579419000087 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416 [article] Mind and gut: Associations between mood and gastrointestinal distress in children exposed to adversity [Texte imprimé et/ou numérique] / Bridget L. CALLAGHAN, Auteur ; Andrea FIELDS, Auteur ; Dylan G. GEE, Auteur ; Laurel GABARD-DURNAM, Auteur ; Christina CALDERA, Auteur ; Kathryn L. HUMPHREYS, Auteur ; Bonnie GOFF, Auteur ; Jessica FLANNERY, Auteur ; Eva H. TELZER, Auteur ; Mor SHAPIRO, Auteur ; Nim TOTTENHAM, Auteur . - p.309-328. Langues : Anglais (eng) in Development and Psychopathology > 32-1 (February 2020) . - p.309-328 Mots-clés : anxiety  development  functional magnetic resonance imaging  gastrointestinal distress  microbiome Index. décimale : PER Périodiques Résumé : Gastrointestinal and mental disorders are highly comorbid, and animal models have shown that both can be caused by early adversity (e.g., parental deprivation). Interactions between the brain and bacteria that live within the gastrointestinal system (the microbiome) underlie adversity-gastrointestinal-anxiety interactions, but these links have not been investigated during human development. In this study, we utilized data from a population of 344 youth (3-18 years old) who were raised with their biological parents or were exposed to early adverse caregiving experiences (i.e., institutional or foster care followed by international adoption) to explore adversity-gastrointestinal-anxiety associations. In Study 1, we demonstrated that previous adverse care experiences were associated with increased incidence of gastrointestinal symptoms in youth. Gastrointestinal symptoms were also associated with concurrent and future anxiety (measured across 5 years), and those gastrointestinal symptoms mediated the adversity-anxiety association at Time 1. In a subsample of children who provided both stool samples and functional magnetic resonance imaging of the brain (Study 2, which was a "proof-of-principle"), adversity was associated with changes in diversity (both alpha and beta) of microbial communities, and bacteria levels (adversity-associated and adversity-independent) were correlated with prefrontal cortex activation to emotional faces. Implications of these data for supporting youth mental health are discussed. En ligne : http://dx.doi.org/10.1017/s0954579419000087 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416

Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms / Michelle R. VANTIEGHEM in Development and Psychopathology, 29-2 (May 2017)  

Public ISBD [article]  inDevelopment and Psychopathology > 29-2 (May 2017) . - p.519-533 Titre : Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Michelle R. VANTIEGHEM, Auteur ; Laurel GABARD-DURNAM, Auteur ; Bonnie GOFF, Auteur ; Jessica FLANNERY, Auteur ; Kathryn L. HUMPHREYS, Auteur ; Eva H. TELZER, Auteur ; Christina CALDERA, Auteur ; Jennifer Y. LOUIE, Auteur ; Mor SHAPIRO, Auteur ; Niall BOLGER, Auteur ; Nim TOTTENHAM, Auteur Article en page(s) : p.519-533 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Institutional caregiving is associated with significant deviations from species-expected caregiving, altering the normative sequence of attachment formation and placing children at risk for long-term emotional difficulties. However, little is known about factors that can promote resilience following early institutional caregiving. In the current study, we investigated how adaptations in affective processing (i.e., positive valence bias) and family-level protective factors (i.e., secure parent–child relationships) moderate risk for internalizing symptoms in previously institutionalized (PI) youth. Children and adolescents with and without a history of institutional care performed a laboratory-based affective processing task and self-reported measures of parent–child relationship security. PI youth were more likely than comparison youth to show positive valence biases when interpreting ambiguous facial expressions. Both positive valence bias and parent–child relationship security moderated the association between institutional care and parent-reported internalizing symptoms, such that greater positive valence bias and more secure parent–child relationships predicted fewer symptoms in PI youth. However, when both factors were tested concurrently, parent–child relationship security more strongly moderated the link between PI status and internalizing symptoms. These findings suggest that both individual-level adaptations in affective processing and family-level factors of secure parent–child relationships may ameliorate risk for internalizing psychopathology following early institutional caregiving. En ligne : http://dx.doi.org/10.1017/s0954579417000153 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 [article] Positive valence bias and parent–child relationship security moderate the association between early institutional caregiving and internalizing symptoms [Texte imprimé et/ou numérique] / Michelle R. VANTIEGHEM, Auteur ; Laurel GABARD-DURNAM, Auteur ; Bonnie GOFF, Auteur ; Jessica FLANNERY, Auteur ; Kathryn L. HUMPHREYS, Auteur ; Eva H. TELZER, Auteur ; Christina CALDERA, Auteur ; Jennifer Y. LOUIE, Auteur ; Mor SHAPIRO, Auteur ; Niall BOLGER, Auteur ; Nim TOTTENHAM, Auteur . - p.519-533. Langues : Anglais (eng) in Development and Psychopathology > 29-2 (May 2017) . - p.519-533 Index. décimale : PER Périodiques Résumé : Institutional caregiving is associated with significant deviations from species-expected caregiving, altering the normative sequence of attachment formation and placing children at risk for long-term emotional difficulties. However, little is known about factors that can promote resilience following early institutional caregiving. In the current study, we investigated how adaptations in affective processing (i.e., positive valence bias) and family-level protective factors (i.e., secure parent–child relationships) moderate risk for internalizing symptoms in previously institutionalized (PI) youth. Children and adolescents with and without a history of institutional care performed a laboratory-based affective processing task and self-reported measures of parent–child relationship security. PI youth were more likely than comparison youth to show positive valence biases when interpreting ambiguous facial expressions. Both positive valence bias and parent–child relationship security moderated the association between institutional care and parent-reported internalizing symptoms, such that greater positive valence bias and more secure parent–child relationships predicted fewer symptoms in PI youth. However, when both factors were tested concurrently, parent–child relationship security more strongly moderated the link between PI status and internalizing symptoms. These findings suggest that both individual-level adaptations in affective processing and family-level factors of secure parent–child relationships may ameliorate risk for internalizing psychopathology following early institutional caregiving. En ligne : http://dx.doi.org/10.1017/s0954579417000153 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

Working memory moderates the association between early institutional care and separation anxiety symptoms in late childhood and adolescence / Laura Alicia ALBA in Development and Psychopathology, 31-3 (August 2019)  

Public ISBD [article]  inDevelopment and Psychopathology > 31-3 (August 2019) . - p.989-997 Titre : Working memory moderates the association between early institutional care and separation anxiety symptoms in late childhood and adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Laura Alicia ALBA, Auteur ; Jessica FLANNERY, Auteur ; Mor SHAPIRO, Auteur ; Nim TOTTENHAM, Auteur Article en page(s) : p.989-997 Langues : Anglais (eng) Mots-clés : cortisol  early caregiving adversity  emotion dysregulation  separation anxiety  working memory Index. décimale : PER Périodiques Résumé : Adverse caregiving, for example, previous institutionalization (PI), is often associated with emotion dysregulation that increases anxiety risk. However, the concept of developmental multifinality predicts heterogeneity in anxiety outcomes. Despite this well-known heterogeneity, more work is needed to identify sources of this heterogeneity and how these sources interact with environmental risk to influence mental health. Here, working memory (WM) was examined during late childhood/adolescence as an intra-individual factor to mitigate the risk for separation anxiety, which is particularly susceptible to caregiving adversities. A modified “object-in-place” task was administered to 110 youths (10–17 years old), with or without a history of PI. The PI youths had elevated separation anxiety scores, which were anticorrelated with morning cortisol levels, yet there were no group differences in WM. PI youths showed significant heterogeneity in separation anxiety symptoms and morning cortisol levels, and WM moderated the link between caregiving and separation anxiety and mediated the association between separation anxiety and morning cortisol in PI youth. Findings suggest that (a) institutional care exerts divergent developmental consequences on separation anxiety versus WM, (b) WM interacts with adversity-related emotion dysregulation, and (c) WM may be a therapeutic target for separation anxiety following early caregiving adversity. En ligne : http://dx.doi.org/10.1017/S0954579419000452 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403 [article] Working memory moderates the association between early institutional care and separation anxiety symptoms in late childhood and adolescence [Texte imprimé et/ou numérique] / Laura Alicia ALBA, Auteur ; Jessica FLANNERY, Auteur ; Mor SHAPIRO, Auteur ; Nim TOTTENHAM, Auteur . - p.989-997. Langues : Anglais (eng) in Development and Psychopathology > 31-3 (August 2019) . - p.989-997 Mots-clés : cortisol  early caregiving adversity  emotion dysregulation  separation anxiety  working memory Index. décimale : PER Périodiques Résumé : Adverse caregiving, for example, previous institutionalization (PI), is often associated with emotion dysregulation that increases anxiety risk. However, the concept of developmental multifinality predicts heterogeneity in anxiety outcomes. Despite this well-known heterogeneity, more work is needed to identify sources of this heterogeneity and how these sources interact with environmental risk to influence mental health. Here, working memory (WM) was examined during late childhood/adolescence as an intra-individual factor to mitigate the risk for separation anxiety, which is particularly susceptible to caregiving adversities. A modified “object-in-place” task was administered to 110 youths (10–17 years old), with or without a history of PI. The PI youths had elevated separation anxiety scores, which were anticorrelated with morning cortisol levels, yet there were no group differences in WM. PI youths showed significant heterogeneity in separation anxiety symptoms and morning cortisol levels, and WM moderated the link between caregiving and separation anxiety and mediated the association between separation anxiety and morning cortisol in PI youth. Findings suggest that (a) institutional care exerts divergent developmental consequences on separation anxiety versus WM, (b) WM interacts with adversity-related emotion dysregulation, and (c) WM may be a therapeutic target for separation anxiety following early caregiving adversity. En ligne : http://dx.doi.org/10.1017/S0954579419000452 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403

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