Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
2 recherche sur le mot-clé 'Attention orienting'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Disrupted Functional Connectivity in Dorsal and Ventral Attention Networks During Attention Orienting in Autism Spectrum Disorders / Jacqueline FITZGERALD in Autism Research, 8-2 (April 2015)
[article]
Titre : Disrupted Functional Connectivity in Dorsal and Ventral Attention Networks During Attention Orienting in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Jacqueline FITZGERALD, Auteur ; Katherine JOHNSON, Auteur ; Elizabeth KEHOE, Auteur ; Arun L. W. BOKDE, Auteur ; Hugh GARAVAN, Auteur ; Louise GALLAGHER, Auteur ; Jane MCGRATH, Auteur Article en page(s) : p.136-152 Langues : Anglais (eng) Mots-clés : autism spectrum disorders functional connectivity attention orienting attention network neuroimaging Index. décimale : PER Périodiques Résumé : Background Attention orienting is a cognitive process that facilitates the movement of attention focus from one location to another: this may be impaired in autism spectrum disorder (ASD). Dorsal and ventral attention networks (DAN and VAN) sub-serve the process of attention orienting. This study investigated the functional connectivity of attention orienting in these networks in ASD using the Posner Cueing Task. Method Twenty-one adolescents with ASD and 21 age and IQ matched controls underwent functional magnetic resonance imaging. A psychophysical interaction (PPI) analysis was implemented to investigate task-dependent functional connectivity, measuring synchronicity of brain regions during the task. Regions of interest (ROI) were selected to explore functional connectivity in the DAN during cue-only conditions and in the VAN during invalid and valid trials. Results Behaviourally, the ASD and control groups performed the task in a similar manner. Functional MRI results indicated that the ASD and control groups activated similar brain regions. During invalid trials (VAN), the ASD group showed significant positive functional connectivity to multiple brain regions, whilst the control group demonstrated negative connectivity. During valid trials (VAN), the two groups also showed contrasting patterns of connectivity. In the cue-only conditions (DAN), the ASD group showed weaker functional connectivity. Conclusion The DAN analysis suggests that the ASD group has weaker coherence between brain areas involved in goal-driven, endogenous attention control. The strong positive functional connectivity exhibited by the ASD group in the VAN during the invalid trials suggests that individuals with ASD may generate compensatory mechanisms to achieve neurotypical behaviour. These results support the theory of abnormal cortical connectivity in autism. En ligne : http://dx.doi.org/10.1002/aur.1430 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=256
in Autism Research > 8-2 (April 2015) . - p.136-152[article] Disrupted Functional Connectivity in Dorsal and Ventral Attention Networks During Attention Orienting in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Jacqueline FITZGERALD, Auteur ; Katherine JOHNSON, Auteur ; Elizabeth KEHOE, Auteur ; Arun L. W. BOKDE, Auteur ; Hugh GARAVAN, Auteur ; Louise GALLAGHER, Auteur ; Jane MCGRATH, Auteur . - p.136-152.
Langues : Anglais (eng)
in Autism Research > 8-2 (April 2015) . - p.136-152
Mots-clés : autism spectrum disorders functional connectivity attention orienting attention network neuroimaging Index. décimale : PER Périodiques Résumé : Background Attention orienting is a cognitive process that facilitates the movement of attention focus from one location to another: this may be impaired in autism spectrum disorder (ASD). Dorsal and ventral attention networks (DAN and VAN) sub-serve the process of attention orienting. This study investigated the functional connectivity of attention orienting in these networks in ASD using the Posner Cueing Task. Method Twenty-one adolescents with ASD and 21 age and IQ matched controls underwent functional magnetic resonance imaging. A psychophysical interaction (PPI) analysis was implemented to investigate task-dependent functional connectivity, measuring synchronicity of brain regions during the task. Regions of interest (ROI) were selected to explore functional connectivity in the DAN during cue-only conditions and in the VAN during invalid and valid trials. Results Behaviourally, the ASD and control groups performed the task in a similar manner. Functional MRI results indicated that the ASD and control groups activated similar brain regions. During invalid trials (VAN), the ASD group showed significant positive functional connectivity to multiple brain regions, whilst the control group demonstrated negative connectivity. During valid trials (VAN), the two groups also showed contrasting patterns of connectivity. In the cue-only conditions (DAN), the ASD group showed weaker functional connectivity. Conclusion The DAN analysis suggests that the ASD group has weaker coherence between brain areas involved in goal-driven, endogenous attention control. The strong positive functional connectivity exhibited by the ASD group in the VAN during the invalid trials suggests that individuals with ASD may generate compensatory mechanisms to achieve neurotypical behaviour. These results support the theory of abnormal cortical connectivity in autism. En ligne : http://dx.doi.org/10.1002/aur.1430 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=256 Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders / Eric R. MURPHY in Journal of Autism and Developmental Disorders, 47-1 (January 2017)
[article]
Titre : Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Eric R. MURPHY, Auteur ; Megan NORR, Auteur ; John F. STRANG, Auteur ; Lauren KENWORTHY, Auteur ; William D. GAILLARD, Auteur ; Chandan J. VAIDYA, Auteur Article en page(s) : p.58-67 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Attention orienting Visual salience fMRI Restricted and repetitive behavior Index. décimale : PER Périodiques Résumé : We examined spontaneous attention orienting to visual salience in stimuli without social significance using a modified Dot-Probe task during functional magnetic resonance imaging in high-functioning preadolescent children with Autism Spectrum Disorder (ASD) and age- and IQ-matched control children. While the magnitude of attentional bias (faster response to probes in the location of solid color patch) to visually salient stimuli was similar in the groups, activation differences in frontal and temporoparietal regions suggested hyper-sensitivity to visual salience or to sameness in ASD children. Further, activation in a subset of those regions was associated with symptoms of restricted and repetitive behavior. Thus, atypicalities in response to visual properties of stimuli may drive attentional orienting problems associated with ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2928-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.58-67[article] Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Eric R. MURPHY, Auteur ; Megan NORR, Auteur ; John F. STRANG, Auteur ; Lauren KENWORTHY, Auteur ; William D. GAILLARD, Auteur ; Chandan J. VAIDYA, Auteur . - p.58-67.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.58-67
Mots-clés : Autism spectrum disorder Attention orienting Visual salience fMRI Restricted and repetitive behavior Index. décimale : PER Périodiques Résumé : We examined spontaneous attention orienting to visual salience in stimuli without social significance using a modified Dot-Probe task during functional magnetic resonance imaging in high-functioning preadolescent children with Autism Spectrum Disorder (ASD) and age- and IQ-matched control children. While the magnitude of attentional bias (faster response to probes in the location of solid color patch) to visually salient stimuli was similar in the groups, activation differences in frontal and temporoparietal regions suggested hyper-sensitivity to visual salience or to sameness in ASD children. Further, activation in a subset of those regions was associated with symptoms of restricted and repetitive behavior. Thus, atypicalities in response to visual properties of stimuli may drive attentional orienting problems associated with ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2928-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298