6 recherche sur le mot-clé 'LMIC'

Ethical Considerations in Conducting Research on Autism Spectrum Disorders in Low and Middle Income Countries / Tamara C. DALEY in Journal of Autism and Developmental Disorders, 43-9 (September 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2002-2014 Titre : Ethical Considerations in Conducting Research on Autism Spectrum Disorders in Low and Middle Income Countries Type de document : Texte imprimé et/ou numérique Auteurs : Tamara C. DALEY, Auteur ; Nidhi SINGHAL, Auteur ; Vibha KRISHNAMURTHY, Auteur Article en page(s) : p.2002-2014 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Ethics  Cross-cultural  ELSI  LMIC  LAMI  Global  India Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is being identified in an ever-increasing number of countries, including many that are low or middle income (LMIC). Research conducted in these countries requires awareness of unique ethical issues. Drawing on the experience of two organizations that have been involved in conducting and collaborating in ASD research in India, we describe specific considerations in conducting epidemiological, genetic and treatment studies as well as general principles from the field of multinational clinical research as they apply to the conduct of ASD research. We argue that greater attention to ethical concerns will result in quality studies conducted in LMICs that are also of greatest relevance for families and children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1750-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 [article] Ethical Considerations in Conducting Research on Autism Spectrum Disorders in Low and Middle Income Countries [Texte imprimé et/ou numérique] / Tamara C. DALEY, Auteur ; Nidhi SINGHAL, Auteur ; Vibha KRISHNAMURTHY, Auteur . - p.2002-2014. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2002-2014 Mots-clés : Autism spectrum disorder  Ethics  Cross-cultural  ELSI  LMIC  LAMI  Global  India Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is being identified in an ever-increasing number of countries, including many that are low or middle income (LMIC). Research conducted in these countries requires awareness of unique ethical issues. Drawing on the experience of two organizations that have been involved in conducting and collaborating in ASD research in India, we describe specific considerations in conducting epidemiological, genetic and treatment studies as well as general principles from the field of multinational clinical research as they apply to the conduct of ASD research. We argue that greater attention to ethical concerns will result in quality studies conducted in LMICs that are also of greatest relevance for families and children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1750-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212

Externalizing behavior in preschool children in a South African birth cohort: Predictive pathways in a high-risk context / Susan MALCOLM-SMITH in Development and Psychopathology, 35-2 (May 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-2 (May 2023) . - p.982-999 Titre : Externalizing behavior in preschool children in a South African birth cohort: Predictive pathways in a high-risk context Type de document : Texte imprimé et/ou numérique Auteurs : Susan MALCOLM-SMITH, Auteur ; Marilyn T. LAKE, Auteur ; Akhona KRWECE, Auteur ; Christopher P. DU PLOOY, Auteur ; Nadia HOFFMAN, Auteur ; Kirsten A. DONALD, Auteur ; Heather J. ZAR, Auteur ; Dan J. STEIN, Auteur Article en page(s) : p.982-999 Langues : Anglais (eng) Mots-clés : preschool mental health  externalizing behavior  LMIC  South Africa  birth cohort Index. décimale : PER Périodiques Résumé : Mental health problems often begin in early childhood. However, the associations of various individual and contextual risk factors with mental health in the preschool period are incompletely understood, particularly in low- to middle-income countries (LMICs) where multiple risk factors co-exist. To address this gap, we prospectively followed 981 children in a South African birth cohort, the Drakenstein Child Health Study, assessing pre-and postnatal exposures and risk factors. The predictive value of these factors for child mental health (assessed by the Child Behavior Checklist) was modeled using structural equation modeling. We identified two key pathways to greater externalizing behavior: (1) prenatal exposure to substances (alcohol and smoking) directly predicted increased externalizing behavior (? = 0.24, p < 0.001); this relationship was partially mediated by an aspect of infant temperament (negative emotionality; ? = 0.05, p = 0.016); (2) lower socioeconomic status and associated maternal prenatal depression predicted more coercive parenting, which in turn predicted increased externalizing behavior (? = 0.18, p = 0.001). Findings in this high-risk LMIC cohort cohere with research from higher income contexts, and indicate the need to introduce integrated screening and intervention strategies for maternal prenatal substance use and depression, and promoting positive parenting across the preschool period. En ligne : http://dx.doi.org/10.1017/S095457942200027X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504 [article] Externalizing behavior in preschool children in a South African birth cohort: Predictive pathways in a high-risk context [Texte imprimé et/ou numérique] / Susan MALCOLM-SMITH, Auteur ; Marilyn T. LAKE, Auteur ; Akhona KRWECE, Auteur ; Christopher P. DU PLOOY, Auteur ; Nadia HOFFMAN, Auteur ; Kirsten A. DONALD, Auteur ; Heather J. ZAR, Auteur ; Dan J. STEIN, Auteur . - p.982-999. Langues : Anglais (eng) in Development and Psychopathology > 35-2 (May 2023) . - p.982-999 Mots-clés : preschool mental health  externalizing behavior  LMIC  South Africa  birth cohort Index. décimale : PER Périodiques Résumé : Mental health problems often begin in early childhood. However, the associations of various individual and contextual risk factors with mental health in the preschool period are incompletely understood, particularly in low- to middle-income countries (LMICs) where multiple risk factors co-exist. To address this gap, we prospectively followed 981 children in a South African birth cohort, the Drakenstein Child Health Study, assessing pre-and postnatal exposures and risk factors. The predictive value of these factors for child mental health (assessed by the Child Behavior Checklist) was modeled using structural equation modeling. We identified two key pathways to greater externalizing behavior: (1) prenatal exposure to substances (alcohol and smoking) directly predicted increased externalizing behavior (? = 0.24, p < 0.001); this relationship was partially mediated by an aspect of infant temperament (negative emotionality; ? = 0.05, p = 0.016); (2) lower socioeconomic status and associated maternal prenatal depression predicted more coercive parenting, which in turn predicted increased externalizing behavior (? = 0.18, p = 0.001). Findings in this high-risk LMIC cohort cohere with research from higher income contexts, and indicate the need to introduce integrated screening and intervention strategies for maternal prenatal substance use and depression, and promoting positive parenting across the preschool period. En ligne : http://dx.doi.org/10.1017/S095457942200027X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504

Autism research capacity building in Northern Mexico: Preliminary evaluation of an ongoing process / Guillermo VELA ; Arturo VELA ; Juan R. MALDONADO CORONADO ; Patricia SANCHEZ LIZARDI ; Diana L. ROBINS in Autism, 28-1 (January 2024)  

Public ISBD [article]  inAutism > 28-1 (January 2024) . - p.229?238 Titre : Autism research capacity building in Northern Mexico: Preliminary evaluation of an ongoing process Type de document : Texte imprimé et/ou numérique Auteurs : Guillermo VELA, Auteur ; Arturo VELA, Auteur ; Juan R. MALDONADO CORONADO, Auteur ; Patricia SANCHEZ LIZARDI, Auteur ; Diana L. ROBINS, Auteur Article en page(s) : p.229?238 Mots-clés : autism  evaluation  LMIC  Mexico  research capacity  research strengthening Index. décimale : PER Périodiques Résumé : Research capacity building is a process by which individuals and organizations develop skills and infrastructure resulting in greater ability to conduct useful research. Frequently, research quality and productivity measures focus on outcomes, such as peer-reviewed publications or grants awarded. Such distal measures are not informative when measuring initial stages of research, a common situation in low- and middle-income countries. This study used Cooke?s six-principle framework to assess the progress of an autism research collaborative in northern Mexico. We established 64 criteria across the six principles and rated them as Not Started, In Progress, or Achieved, based on narratives and process documentation collected for this purpose. Ratings were established for the years 2018, 2020, and 2022, which correspond to Years 5, 7, and 9 since the beginning of the collaborative, respectively. As of 2022, Principles 2 and 3 (?Close to practice? and ?Linkages, collaborations, and partnerships,? respectively) had all begun; no criteria were rated as Not started. The principles with the highest Achieved rates were ?Linkages, collaborations, and partnerships? (90%), and ?Infrastructure? (Principle 6, 70%). Cooke?s research capacity building framework is a useful way to monitor progress of research capacity building and contribute to harmonious development of relevant principles at different levels. Lay abstract To inform improvement of care and public policy, quality research is required. Conducting research projects requires skills and infrastructure. Research capacity building is the process by which individuals and organizations develop greater ability to conduct useful research. However, in the scientific community, research quality and productivity measures are often focused on long-term products, such as publications or grants awarded. Those measures are not helpful when measuring initial stages of research, a common situation in low- and middle-income countries. We used a six-principle framework designed by J. Cooke to assess the progress of an autism research collaborative in northern Mexico. We established 64 criteria across the six principles, and rated them as Not Started, In Progress, or Achieved, based on narratives and process documentation collected for this purpose. Ratings were established for the Years 2018, 2020, and 2022. The principles with the highest Achieved rates were ?Linkages, collaborations, and partnerships? (90%), and ?Infrastructure? (Principle 6, 70%). Cooke?s research capacity building framework is a useful way to monitor progress of research capacity building and contribute to harmonious development of relevant principles at different levels. En ligne : https://dx.doi.org/10.1177/13623613221145787 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519 [article] Autism research capacity building in Northern Mexico: Preliminary evaluation of an ongoing process [Texte imprimé et/ou numérique] / Guillermo VELA, Auteur ; Arturo VELA, Auteur ; Juan R. MALDONADO CORONADO, Auteur ; Patricia SANCHEZ LIZARDI, Auteur ; Diana L. ROBINS, Auteur . - p.229?238. in Autism > 28-1 (January 2024) . - p.229?238 Mots-clés : autism  evaluation  LMIC  Mexico  research capacity  research strengthening Index. décimale : PER Périodiques Résumé : Research capacity building is a process by which individuals and organizations develop skills and infrastructure resulting in greater ability to conduct useful research. Frequently, research quality and productivity measures focus on outcomes, such as peer-reviewed publications or grants awarded. Such distal measures are not informative when measuring initial stages of research, a common situation in low- and middle-income countries. This study used Cooke?s six-principle framework to assess the progress of an autism research collaborative in northern Mexico. We established 64 criteria across the six principles and rated them as Not Started, In Progress, or Achieved, based on narratives and process documentation collected for this purpose. Ratings were established for the years 2018, 2020, and 2022, which correspond to Years 5, 7, and 9 since the beginning of the collaborative, respectively. As of 2022, Principles 2 and 3 (?Close to practice? and ?Linkages, collaborations, and partnerships,? respectively) had all begun; no criteria were rated as Not started. The principles with the highest Achieved rates were ?Linkages, collaborations, and partnerships? (90%), and ?Infrastructure? (Principle 6, 70%). Cooke?s research capacity building framework is a useful way to monitor progress of research capacity building and contribute to harmonious development of relevant principles at different levels. Lay abstract To inform improvement of care and public policy, quality research is required. Conducting research projects requires skills and infrastructure. Research capacity building is the process by which individuals and organizations develop greater ability to conduct useful research. However, in the scientific community, research quality and productivity measures are often focused on long-term products, such as publications or grants awarded. Those measures are not helpful when measuring initial stages of research, a common situation in low- and middle-income countries. We used a six-principle framework designed by J. Cooke to assess the progress of an autism research collaborative in northern Mexico. We established 64 criteria across the six principles, and rated them as Not Started, In Progress, or Achieved, based on narratives and process documentation collected for this purpose. Ratings were established for the Years 2018, 2020, and 2022. The principles with the highest Achieved rates were ?Linkages, collaborations, and partnerships? (90%), and ?Infrastructure? (Principle 6, 70%). Cooke?s research capacity building framework is a useful way to monitor progress of research capacity building and contribute to harmonious development of relevant principles at different levels. En ligne : https://dx.doi.org/10.1177/13623613221145787 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519

Autism spectrum disorder in sub-saharan africa: A comprehensive scoping review / Lauren FRANZ in Autism Research, 10-5 (May 2017)  

Public ISBD [article]  inAutism Research > 10-5 (May 2017) . - p.723-749 Titre : Autism spectrum disorder in sub-saharan africa: A comprehensive scoping review Type de document : Texte imprimé et/ou numérique Auteurs : Lauren FRANZ, Auteur ; Nola J. CHAMBERS, Auteur ; Megan VON ISENBURG, Auteur ; Petrus J. DE VRIES, Auteur Article en page(s) : p.723-749 Langues : Anglais (eng) Mots-clés : autism  autism spectrum disorder  low- and middle-income countries  LMIC  low resource environments  Africa Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is recognized as a global public health concern, yet almost everything we know about ASD comes from high-income countries. Here we performed a scoping review of all research on ASD ever published in sub-Saharan Africa (SSA) in order to identify ASD knowledge gaps in this part of the world. Fifty-three publications met inclusion criteria. Themes included the phenotype, genetics and risk factors for ASD in SSA, screening and diagnosis, professional knowledge, interventions for ASD, parental perceptions, and social-cognitive neuroscience. No epidemiological, early intervention, school-based or adult studies were identified. For each identified theme, we aimed to summarize results and make recommendations to fill the knowledge gaps. The quality of study methodologies was generally not high. Few studies used standardized diagnostic instruments, and intervention studies were typically small-scale. Overall, findings suggest a substantial need for large-scale clinical, training, and research programmes to improve the lives of people who live with ASD in SSA. However, SSA also has the potential to make unique and globally-significant contributions to the etiology and treatments of ASD through implementation, interventional, and comparative genomic science. En ligne : http://dx.doi.org/10.1002/aur.1766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307 [article] Autism spectrum disorder in sub-saharan africa: A comprehensive scoping review [Texte imprimé et/ou numérique] / Lauren FRANZ, Auteur ; Nola J. CHAMBERS, Auteur ; Megan VON ISENBURG, Auteur ; Petrus J. DE VRIES, Auteur . - p.723-749. Langues : Anglais (eng) in Autism Research > 10-5 (May 2017) . - p.723-749 Mots-clés : autism  autism spectrum disorder  low- and middle-income countries  LMIC  low resource environments  Africa Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is recognized as a global public health concern, yet almost everything we know about ASD comes from high-income countries. Here we performed a scoping review of all research on ASD ever published in sub-Saharan Africa (SSA) in order to identify ASD knowledge gaps in this part of the world. Fifty-three publications met inclusion criteria. Themes included the phenotype, genetics and risk factors for ASD in SSA, screening and diagnosis, professional knowledge, interventions for ASD, parental perceptions, and social-cognitive neuroscience. No epidemiological, early intervention, school-based or adult studies were identified. For each identified theme, we aimed to summarize results and make recommendations to fill the knowledge gaps. The quality of study methodologies was generally not high. Few studies used standardized diagnostic instruments, and intervention studies were typically small-scale. Overall, findings suggest a substantial need for large-scale clinical, training, and research programmes to improve the lives of people who live with ASD in SSA. However, SSA also has the potential to make unique and globally-significant contributions to the etiology and treatments of ASD through implementation, interventional, and comparative genomic science. En ligne : http://dx.doi.org/10.1002/aur.1766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307

Glocalizing project ImPACT: Feasibility, acceptability and preliminary outcomes of a parent-mediated social communication intervention for autism adapted to the Indian context / Koyeli SENGUPTA in Research in Autism Spectrum Disorders, 76 (August 2020)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 76 (August 2020) . - p.101585 Titre : Glocalizing project ImPACT: Feasibility, acceptability and preliminary outcomes of a parent-mediated social communication intervention for autism adapted to the Indian context Type de document : Texte imprimé et/ou numérique Auteurs : Koyeli SENGUPTA, Auteur ; Sanchita MAHADIK, Auteur ; Gopika KAPOOR, Auteur Article en page(s) : p.101585 Langues : Anglais (eng) Mots-clés : Autism  Parent-mediated intervention  Cultural adaptation  Feasibility  Project ImPACT  LMIC Index. décimale : PER Périodiques Résumé : Background Parent mediated intervention programs for children with Autism Spectrum Disorders (ASD) assume great importance in resource-poor communities in Low and Middle-Income Countries. However, very few evidence-based, manualized, and replicable programs have been documented in such settings. Methods Project ImPACT (Ingersoll & Dvortcsak, 2010)- a parent-mediated Naturalistic Developmental Behavioral Intervention (NDBI) for young children with ASD shown to improve social communication, engagement and play was adapted and subsequently implemented at a child development center in an urban setting in India to meet the needs of the community. A quasi-experimental pre-post study design was utilized, with questionnaires about family satisfaction, parent-perceived social-communication skills of children, and parental stress used to gather information. Video-recordings of parent-child interaction were coded to assess parent fidelity. Caregivers of 57 children enrolled in the Intervention, with complete data for feasibility and acceptability of the intervention as well as parent-perceived outcomes available for 39 (n?=?39). Results Results showed that urban Indian parents found the intervention feasible and acceptable, were able to demonstrate the strategies taught and perceived improvement in their children’s social communication skills. In addition, parent stress levels decreased after completion of the intervention. Conclusion Findings suggest that brief parent-mediated intervention interventions like Project ImPACT can be successfully implemented in low-resource, culturally diverse settings, thereby opening avenues for replication and expansion of much-needed services in this region. En ligne : https://doi.org/10.1016/j.rasd.2020.101585 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Glocalizing project ImPACT: Feasibility, acceptability and preliminary outcomes of a parent-mediated social communication intervention for autism adapted to the Indian context [Texte imprimé et/ou numérique] / Koyeli SENGUPTA, Auteur ; Sanchita MAHADIK, Auteur ; Gopika KAPOOR, Auteur . - p.101585. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 76 (August 2020) . - p.101585 Mots-clés : Autism  Parent-mediated intervention  Cultural adaptation  Feasibility  Project ImPACT  LMIC Index. décimale : PER Périodiques Résumé : Background Parent mediated intervention programs for children with Autism Spectrum Disorders (ASD) assume great importance in resource-poor communities in Low and Middle-Income Countries. However, very few evidence-based, manualized, and replicable programs have been documented in such settings. Methods Project ImPACT (Ingersoll & Dvortcsak, 2010)- a parent-mediated Naturalistic Developmental Behavioral Intervention (NDBI) for young children with ASD shown to improve social communication, engagement and play was adapted and subsequently implemented at a child development center in an urban setting in India to meet the needs of the community. A quasi-experimental pre-post study design was utilized, with questionnaires about family satisfaction, parent-perceived social-communication skills of children, and parental stress used to gather information. Video-recordings of parent-child interaction were coded to assess parent fidelity. Caregivers of 57 children enrolled in the Intervention, with complete data for feasibility and acceptability of the intervention as well as parent-perceived outcomes available for 39 (n?=?39). Results Results showed that urban Indian parents found the intervention feasible and acceptable, were able to demonstrate the strategies taught and perceived improvement in their children’s social communication skills. In addition, parent stress levels decreased after completion of the intervention. Conclusion Findings suggest that brief parent-mediated intervention interventions like Project ImPACT can be successfully implemented in low-resource, culturally diverse settings, thereby opening avenues for replication and expansion of much-needed services in this region. En ligne : https://doi.org/10.1016/j.rasd.2020.101585 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

Using mobile health technology to assess childhood autism in low-resource community settings in India: An innovation to address the detection gap / Indu DUBEY in Autism, 28-3 (March 2024)  

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