4 recherche sur le mot-clé 'Mismatch negativity (MMN)'

Atypical mismatch negativity to distressful voices associated with conduct disorder symptoms / An-Yi HUNG in Journal of Child Psychology and Psychiatry, 54-9 (September 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-9 (September 2013) . - p.1016-1027 Titre : Atypical mismatch negativity to distressful voices associated with conduct disorder symptoms Type de document : Texte imprimé et/ou numérique Auteurs : An-Yi HUNG, Auteur ; Jyrki AHVENINEN, Auteur ; Yawei CHENG, Auteur Article en page(s) : p.1016-1027 Langues : Anglais (eng) Mots-clés : Conduct disorder (CD)  distressful voices  impulsivity  juvenile delinquents  mismatch negativity (MMN) Index. décimale : PER Périodiques Résumé : Background Although a general consensus holds that emotional reactivity in youth with conduct disorder (CD) symptoms arises as one of the main causes of successive aggression, it remains to be determined whether automatic emotional processing is altered in this population. Methods We measured auditory event-related potentials (ERP) in 20 young offenders and 20 controls, screened for DSM-IV criteria of CD and evaluated using the youth version of Hare Psychopathy Checklist (PCL:YV), State-Trait Anxiety Inventory (STAI) and Barrett Impulsiveness Scale (BIS-11). In an oddball design, sadly or fearfully spoken ‘deviant’ syllables were randomly presented within a train of emotionally neutral ‘standard’ syllables. Results In young offenders meeting with CD criteria, the ERP component mismatch negativity (MMN), presumed to reflect preattentive auditory change detection, was significantly stronger for fearful than sad syllables. No MMN differences for fearful versus sad syllables were observed in controls. Analyses of nonvocal deviants, matched spectrally with the fearful and sad sounds, supported our interpretation that the MMN abnormalities in juvenile offenders were related to the emotional content of sounds, instead of purely acoustic factors. Further, in the young offenders with CD symptoms, strong MMN amplitudes to fearful syllables were associated with high impulsive tendencies (PCL:YV, Factor 2). Higher trait and state anxiety, assessed by STAI, were positively correlated with P3a amplitudes to fearful and sad syllables, respectively. The differences in group-interaction MMN/P3a patterns to emotional syllables and nonvocal sounds could be speculated to suggest that there is a distinct processing route for preattentive processing of species-specific emotional information in human auditory cortices. Conclusions Our results suggest that youths with CD symptoms may process distressful voices in an atypical fashion already at the preattentive level. This auditory processing abnormality correlated with increased impulsivity and anxiety. Our results may help to shed light on the neural mechanisms of aggression. En ligne : http://dx.doi.org/10.1111/jcpp.12076 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 [article] Atypical mismatch negativity to distressful voices associated with conduct disorder symptoms [Texte imprimé et/ou numérique] / An-Yi HUNG, Auteur ; Jyrki AHVENINEN, Auteur ; Yawei CHENG, Auteur . - p.1016-1027. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-9 (September 2013) . - p.1016-1027 Mots-clés : Conduct disorder (CD)  distressful voices  impulsivity  juvenile delinquents  mismatch negativity (MMN) Index. décimale : PER Périodiques Résumé : Background Although a general consensus holds that emotional reactivity in youth with conduct disorder (CD) symptoms arises as one of the main causes of successive aggression, it remains to be determined whether automatic emotional processing is altered in this population. Methods We measured auditory event-related potentials (ERP) in 20 young offenders and 20 controls, screened for DSM-IV criteria of CD and evaluated using the youth version of Hare Psychopathy Checklist (PCL:YV), State-Trait Anxiety Inventory (STAI) and Barrett Impulsiveness Scale (BIS-11). In an oddball design, sadly or fearfully spoken ‘deviant’ syllables were randomly presented within a train of emotionally neutral ‘standard’ syllables. Results In young offenders meeting with CD criteria, the ERP component mismatch negativity (MMN), presumed to reflect preattentive auditory change detection, was significantly stronger for fearful than sad syllables. No MMN differences for fearful versus sad syllables were observed in controls. Analyses of nonvocal deviants, matched spectrally with the fearful and sad sounds, supported our interpretation that the MMN abnormalities in juvenile offenders were related to the emotional content of sounds, instead of purely acoustic factors. Further, in the young offenders with CD symptoms, strong MMN amplitudes to fearful syllables were associated with high impulsive tendencies (PCL:YV, Factor 2). Higher trait and state anxiety, assessed by STAI, were positively correlated with P3a amplitudes to fearful and sad syllables, respectively. The differences in group-interaction MMN/P3a patterns to emotional syllables and nonvocal sounds could be speculated to suggest that there is a distinct processing route for preattentive processing of species-specific emotional information in human auditory cortices. Conclusions Our results suggest that youths with CD symptoms may process distressful voices in an atypical fashion already at the preattentive level. This auditory processing abnormality correlated with increased impulsivity and anxiety. Our results may help to shed light on the neural mechanisms of aggression. En ligne : http://dx.doi.org/10.1111/jcpp.12076 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212

Emotional prosodic change detection in autism Spectrum disorder: an electrophysiological investigation in children and adults / J. CHARPENTIER in Journal of Neurodevelopmental Disorders, 10-1 (December 2018)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 10-1 (December 2018) . - 28 p. Titre : Emotional prosodic change detection in autism Spectrum disorder: an electrophysiological investigation in children and adults Type de document : Texte imprimé et/ou numérique Auteurs : J. CHARPENTIER, Auteur ; K. KOVARSKI, Auteur ; Emmanuelle HOUY-DURAND, Auteur ; J. MALVY, Auteur ; A. SABY, Auteur ; Frédérique BONNET-BRILHAULT, Auteur ; Marianne LATINUS, Auteur ; Marie GOMOT, Auteur Année de publication : 2018 Article en page(s) : 28 p. Langues : Anglais (eng) Mots-clés : Adults  Autism spectrum disorder  Change detection  Children  Eeg  Emotion  Mismatch negativity (MMN)  Prosody Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) is characterized by atypical behaviors in social environments and in reaction to changing events. While this dyad of symptoms is at the core of the pathology along with atypical sensory behaviors, most studies have investigated only one dimension. A focus on the sameness dimension has shown that intolerance to change is related to an atypical pre-attentional detection of irregularity. In the present study, we addressed the same process in response to emotional change in order to evaluate the interplay between alterations of change detection and socio-emotional processing in children and adults with autism. METHODS: Brain responses to neutral and emotional prosodic deviancies (mismatch negativity (MMN) and P3a, reflecting change detection and orientation of attention toward change, respectively) were recorded in children and adults with autism and in controls. Comparison of neutral and emotional conditions allowed distinguishing between general deviancy and emotional deviancy effects. Moreover, brain responses to the same neutral and emotional stimuli were recorded when they were not deviants to evaluate the sensory processing of these vocal stimuli. RESULTS: In controls, change detection was modulated by prosody: in children, this was characterized by a lateralization of emotional MMN to the right hemisphere, and in adults, by an earlier MMN for emotional deviancy than for neutral deviancy. In ASD, an overall atypical change detection was observed with an earlier MMN and a larger P3a compared to controls suggesting an unusual pre-attentional orientation toward any changes in the auditory environment. Moreover, in children with autism, deviancy detection depicted reduced MMN amplitude. In addition in children with autism, contrary to adults with autism, no modulation of the MMN by prosody was present and sensory processing of both neutral and emotional vocal stimuli appeared atypical. CONCLUSIONS: Overall, change detection remains altered in people with autism. However, differences between children and adults with ASD evidence a trend toward normalization of vocal processing and of the automatic detection of emotion deviancy with age. En ligne : http://dx.doi.org/10.1186/s11689-018-9246-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 [article] Emotional prosodic change detection in autism Spectrum disorder: an electrophysiological investigation in children and adults [Texte imprimé et/ou numérique] / J. CHARPENTIER, Auteur ; K. KOVARSKI, Auteur ; Emmanuelle HOUY-DURAND, Auteur ; J. MALVY, Auteur ; A. SABY, Auteur ; Frédérique BONNET-BRILHAULT, Auteur ; Marianne LATINUS, Auteur ; Marie GOMOT, Auteur . - 2018 . - 28 p. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 10-1 (December 2018) . - 28 p. Mots-clés : Adults  Autism spectrum disorder  Change detection  Children  Eeg  Emotion  Mismatch negativity (MMN)  Prosody Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) is characterized by atypical behaviors in social environments and in reaction to changing events. While this dyad of symptoms is at the core of the pathology along with atypical sensory behaviors, most studies have investigated only one dimension. A focus on the sameness dimension has shown that intolerance to change is related to an atypical pre-attentional detection of irregularity. In the present study, we addressed the same process in response to emotional change in order to evaluate the interplay between alterations of change detection and socio-emotional processing in children and adults with autism. METHODS: Brain responses to neutral and emotional prosodic deviancies (mismatch negativity (MMN) and P3a, reflecting change detection and orientation of attention toward change, respectively) were recorded in children and adults with autism and in controls. Comparison of neutral and emotional conditions allowed distinguishing between general deviancy and emotional deviancy effects. Moreover, brain responses to the same neutral and emotional stimuli were recorded when they were not deviants to evaluate the sensory processing of these vocal stimuli. RESULTS: In controls, change detection was modulated by prosody: in children, this was characterized by a lateralization of emotional MMN to the right hemisphere, and in adults, by an earlier MMN for emotional deviancy than for neutral deviancy. In ASD, an overall atypical change detection was observed with an earlier MMN and a larger P3a compared to controls suggesting an unusual pre-attentional orientation toward any changes in the auditory environment. Moreover, in children with autism, deviancy detection depicted reduced MMN amplitude. In addition in children with autism, contrary to adults with autism, no modulation of the MMN by prosody was present and sensory processing of both neutral and emotional vocal stimuli appeared atypical. CONCLUSIONS: Overall, change detection remains altered in people with autism. However, differences between children and adults with ASD evidence a trend toward normalization of vocal processing and of the automatic detection of emotion deviancy with age. En ligne : http://dx.doi.org/10.1186/s11689-018-9246-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386

Candidate Electrophysiological Endophenotypes of Hyper-Reactivity to Change in Autism / Marie GOMOT in Journal of Autism and Developmental Disorders, 41-6 (June 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-6 (June 2011) . - p.705-714 Titre : Candidate Electrophysiological Endophenotypes of Hyper-Reactivity to Change in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Marie GOMOT, Auteur ; Romuald BLANC, Auteur ; Helen CLERY, Auteur ; Sylvie ROUX, Auteur ; Catherine BARTHELEMY, Auteur ; Nicole BRUNEAU, Auteur Année de publication : 2011 Article en page(s) : p.705-714 Langues : Anglais (eng) Mots-clés : Autism  Change processing  Auditory evoked potential (AEP)  Mismatch negativity (MMN)  P3a  Children Index. décimale : PER Périodiques Résumé : Although resistance to change is a main feature of autism, the brain processes underlying this aspect of the disorder remain poorly understood. The aims of this study were to examine neural basis of auditory change-detection in children with autism spectrum disorders (ASD; N = 27) through electrophysiological patterns (MMN, P3a) and to test whether these are quantitatively related to intolerance of change (using the BSE-R scale). ASD displayed significantly shorter MMN latency and larger P3a than controls, indicating a greater tendency to switch attention to deviant events. These electrophysiological abnormalities were significantly more marked in children who displayed greater difficulties in tolerating change. The atypical neurophysiological mechanism of change perception identified might thus be associated with one of the hallmark behavioural manifestations of autism. En ligne : http://dx.doi.org/10.1007/s10803-010-1091-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=127 [article] Candidate Electrophysiological Endophenotypes of Hyper-Reactivity to Change in Autism [Texte imprimé et/ou numérique] / Marie GOMOT, Auteur ; Romuald BLANC, Auteur ; Helen CLERY, Auteur ; Sylvie ROUX, Auteur ; Catherine BARTHELEMY, Auteur ; Nicole BRUNEAU, Auteur . - 2011 . - p.705-714. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-6 (June 2011) . - p.705-714 Mots-clés : Autism  Change processing  Auditory evoked potential (AEP)  Mismatch negativity (MMN)  P3a  Children Index. décimale : PER Périodiques Résumé : Although resistance to change is a main feature of autism, the brain processes underlying this aspect of the disorder remain poorly understood. The aims of this study were to examine neural basis of auditory change-detection in children with autism spectrum disorders (ASD; N = 27) through electrophysiological patterns (MMN, P3a) and to test whether these are quantitatively related to intolerance of change (using the BSE-R scale). ASD displayed significantly shorter MMN latency and larger P3a than controls, indicating a greater tendency to switch attention to deviant events. These electrophysiological abnormalities were significantly more marked in children who displayed greater difficulties in tolerating change. The atypical neurophysiological mechanism of change perception identified might thus be associated with one of the hallmark behavioural manifestations of autism. En ligne : http://dx.doi.org/10.1007/s10803-010-1091-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=127

Pitch Processing in Tonal-Language-Speaking Children with Autism: An Event-Related Potential Study / Luodi YU in Journal of Autism and Developmental Disorders, 45-11 (November 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-11 (November 2015) . - p.3656-3667 Titre : Pitch Processing in Tonal-Language-Speaking Children with Autism: An Event-Related Potential Study Type de document : Texte imprimé et/ou numérique Auteurs : Luodi YU, Auteur ; Yuebo FAN, Auteur ; Zhizhou DENG, Auteur ; Dan HUANG, Auteur ; Suiping WANG, Auteur ; Yang ZHANG, Auteur Article en page(s) : p.3656-3667 Langues : Anglais (eng) Mots-clés : Autism  Pitch processing  Speech perception  Language development  Event-related potentials (ERPs)  Mismatch negativity (MMN) Index. décimale : PER Périodiques Résumé : The present study investigated pitch processing in Mandarin-speaking children with autism using event-related potential measures. Two experiments were designed to test how acoustic, phonetic and semantic properties of the stimuli contributed to the neural responses for pitch change detection and involuntary attentional orienting. In comparison with age-matched (6–12 years) typically developing controls (16 participants in Experiment 1, 18 in Experiment 2), children with autism (18 participants in Experiment 1, 16 in Experiment 2) showed enhanced neural discriminatory sensitivity in the nonspeech conditions but not for speech stimuli. The results indicate domain specificity of enhanced pitch processing in autism, which may interfere with lexical tone acquisition and language development for children who speak a tonal language. En ligne : http://dx.doi.org/10.1007/s10803-015-2510-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 [article] Pitch Processing in Tonal-Language-Speaking Children with Autism: An Event-Related Potential Study [Texte imprimé et/ou numérique] / Luodi YU, Auteur ; Yuebo FAN, Auteur ; Zhizhou DENG, Auteur ; Dan HUANG, Auteur ; Suiping WANG, Auteur ; Yang ZHANG, Auteur . - p.3656-3667. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-11 (November 2015) . - p.3656-3667 Mots-clés : Autism  Pitch processing  Speech perception  Language development  Event-related potentials (ERPs)  Mismatch negativity (MMN) Index. décimale : PER Périodiques Résumé : The present study investigated pitch processing in Mandarin-speaking children with autism using event-related potential measures. Two experiments were designed to test how acoustic, phonetic and semantic properties of the stimuli contributed to the neural responses for pitch change detection and involuntary attentional orienting. In comparison with age-matched (6–12 years) typically developing controls (16 participants in Experiment 1, 18 in Experiment 2), children with autism (18 participants in Experiment 1, 16 in Experiment 2) showed enhanced neural discriminatory sensitivity in the nonspeech conditions but not for speech stimuli. The results indicate domain specificity of enhanced pitch processing in autism, which may interfere with lexical tone acquisition and language development for children who speak a tonal language. En ligne : http://dx.doi.org/10.1007/s10803-015-2510-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270