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Characterizing the Factor Structure of Parent Reported Executive Function in Autism Spectrum Disorders: The Impact of Cognitive Inflexibility / Yael GRANADER in Journal of Autism and Developmental Disorders, 44-12 (December 2014)
[article]
Titre : Characterizing the Factor Structure of Parent Reported Executive Function in Autism Spectrum Disorders: The Impact of Cognitive Inflexibility Type de document : Texte imprimé et/ou numérique Auteurs : Yael GRANADER, Auteur ; Gregory L. WALLACE, Auteur ; Kristina K. HARDY, Auteur ; Benjamin E. YERYS, Auteur ; Rachel A. LAWSON, Auteur ; Michael ROSENTHAL, Auteur ; Meagan C. WILLS, Auteur ; Eunice DIXON, Auteur ; Juhi PANDEY, Auteur ; Rebecca PENNA, Auteur ; Robert T. SCHULTZ, Auteur ; Lauren KENWORTHY, Auteur Article en page(s) : p.3056-3062 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Cognitive flexibility Executive functioning Behavior Rating Inventory of Executive Function Factor analysis Index. décimale : PER Périodiques Résumé : Parents of children with autism spectrum disorders (ASD) consistently report executive functioning (EF) deficits. This study investigates the factor structure of the Behavior Rating Inventory of Executive Function (BRIEF) as reported by parents of children with ASD and typically developing children (TDC). BRIEFs for 411 children with ASD and 467 TDC were examined. Confirmatory factor analysis of a nine-factor model met thresholds for goodness-of-fit in TDC, but not in the ASD sample. We found globally elevated EF problems in the ASD sample, especially on the Shift scale. These findings confirm that children with ASD exhibit significant EF deficits. Further investigation is needed to understand the pervasive nature of cognitive inflexibility in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2169-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243
in Journal of Autism and Developmental Disorders > 44-12 (December 2014) . - p.3056-3062[article] Characterizing the Factor Structure of Parent Reported Executive Function in Autism Spectrum Disorders: The Impact of Cognitive Inflexibility [Texte imprimé et/ou numérique] / Yael GRANADER, Auteur ; Gregory L. WALLACE, Auteur ; Kristina K. HARDY, Auteur ; Benjamin E. YERYS, Auteur ; Rachel A. LAWSON, Auteur ; Michael ROSENTHAL, Auteur ; Meagan C. WILLS, Auteur ; Eunice DIXON, Auteur ; Juhi PANDEY, Auteur ; Rebecca PENNA, Auteur ; Robert T. SCHULTZ, Auteur ; Lauren KENWORTHY, Auteur . - p.3056-3062.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-12 (December 2014) . - p.3056-3062
Mots-clés : Autism spectrum disorder Cognitive flexibility Executive functioning Behavior Rating Inventory of Executive Function Factor analysis Index. décimale : PER Périodiques Résumé : Parents of children with autism spectrum disorders (ASD) consistently report executive functioning (EF) deficits. This study investigates the factor structure of the Behavior Rating Inventory of Executive Function (BRIEF) as reported by parents of children with ASD and typically developing children (TDC). BRIEFs for 411 children with ASD and 467 TDC were examined. Confirmatory factor analysis of a nine-factor model met thresholds for goodness-of-fit in TDC, but not in the ASD sample. We found globally elevated EF problems in the ASD sample, especially on the Shift scale. These findings confirm that children with ASD exhibit significant EF deficits. Further investigation is needed to understand the pervasive nature of cognitive inflexibility in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2169-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 Parent Reports of Executive Function Associated with Functional Communication and Conversational Skills Among School Age Children With and Without Autism Spectrum Disorder / Sarah M. HUTCHISON in Journal of Autism and Developmental Disorders, 50-6 (June 2020)
[article]
Titre : Parent Reports of Executive Function Associated with Functional Communication and Conversational Skills Among School Age Children With and Without Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Sarah M. HUTCHISON, Auteur ; Ulrich MÜLLER, Auteur ; Grace IAROCCI, Auteur Article en page(s) : p.2019-2029 Langues : Anglais (eng) Mots-clés : Behavior assessment system for children-second edition Behavior rating inventory of executive function Multidimensional social competence scale Verbal conversation Youth Index. décimale : PER Périodiques Résumé : Despite average or above cognitive and verbal abilities, many children with autism spectrum disorder (ASD) experience difficulties in functional and social communication. Executive functioning (EF) may be the cognitive and regulatory mechanism that underlies these difficulties. Parents rated 92 children with ASD as demonstrating significantly more challenges than 94 typically developing children on measures of EF (Behavior Rating Inventory of Executive Function; BRIEF), functional communication (FC), and verbal conversation (VC) skills. For both groups, the BRIEF metacognition scale emerged as a strong predictor of FC, while the BRIEF behavior regulation and the inhibit scale were predictive of VC skills. These findings suggest that targeting EF domains specifically may improve FC and VC skills in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-03958-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=425
in Journal of Autism and Developmental Disorders > 50-6 (June 2020) . - p.2019-2029[article] Parent Reports of Executive Function Associated with Functional Communication and Conversational Skills Among School Age Children With and Without Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Sarah M. HUTCHISON, Auteur ; Ulrich MÜLLER, Auteur ; Grace IAROCCI, Auteur . - p.2019-2029.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-6 (June 2020) . - p.2019-2029
Mots-clés : Behavior assessment system for children-second edition Behavior rating inventory of executive function Multidimensional social competence scale Verbal conversation Youth Index. décimale : PER Périodiques Résumé : Despite average or above cognitive and verbal abilities, many children with autism spectrum disorder (ASD) experience difficulties in functional and social communication. Executive functioning (EF) may be the cognitive and regulatory mechanism that underlies these difficulties. Parents rated 92 children with ASD as demonstrating significantly more challenges than 94 typically developing children on measures of EF (Behavior Rating Inventory of Executive Function; BRIEF), functional communication (FC), and verbal conversation (VC) skills. For both groups, the BRIEF metacognition scale emerged as a strong predictor of FC, while the BRIEF behavior regulation and the inhibit scale were predictive of VC skills. These findings suggest that targeting EF domains specifically may improve FC and VC skills in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-03958-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=425 Autism spectrum disorder polygenic scores are associated with every day executive function in children admitted for clinical assessment / Tonje TORSKE in Autism Research, 13-2 (February 2020)
[article]
Titre : Autism spectrum disorder polygenic scores are associated with every day executive function in children admitted for clinical assessment Type de document : Texte imprimé et/ou numérique Auteurs : Tonje TORSKE, Auteur ; Terje NAERLAND, Auteur ; Francesco BETTELLA, Auteur ; Thomas BJELLA, Auteur ; Eva MALT, Auteur ; Anne Lise HOYLAND, Auteur ; Nina STENBERG, Auteur ; Merete Glenne OIE, Auteur ; Ole A. ANDREASSEN, Auteur Article en page(s) : p.207-220 Langues : Anglais (eng) Mots-clés : attention deficit/hyperactivity disorder autism spectrum disorder behavior rating inventory of executive function executive function polygenic score Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDs) are behaviorally defined disorders with overlapping clinical features that are often associated with higher-order cognitive dysfunction, particularly executive dysfunction. Our aim was to determine if the polygenic score (PGS) for ASD is associated with parent-reported executive dysfunction in everyday life using the Behavior Rating Inventory of Executive Function (BRIEF). Furthermore, we investigated if PGS for general intelligence (INT) and attention deficit/hyperactivity disorder (ADHD) also correlate with BRIEF. We included 176 children, adolescents and young adults aged 5-22 years with full-scale intelligence quotient (IQ) above 70. All were admitted for clinical assessment of ASD symptoms and 68% obtained an ASD diagnosis. We found a significant difference between low and high ASD PGS groups in the BRIEF behavior regulation index (BRI) (P = 0.015, Cohen's d = 0.69). A linear regression model accounting for age, sex, full-scale IQ, Social Responsiveness Scale (SRS) total score, ASD, ADHD and INT PGS groups as well as genetic principal components, significantly predicted the BRI score; F(11,130) = 8.142, P < 0.001, R(2) = 0.41 (unadjusted). Only SRS total (P < 0.001), ASD PGS 0.1 group (P = 0.018), and sex (P = 0.022) made a significant contribution to the model. This suggests that the common ASD risk gene variants have a stronger association to behavioral regulation aspects of executive dysfunction than ADHD risk or INT variants in a clinical sample with ASD symptoms. Autism Res 2020, 13: 207-220. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: People with autism spectrum disorder (ASD) often have difficulties with higher-order cognitive processes that regulate thoughts and actions during goal-directed behavior, also known as executive function (EF). We studied the association between genetics related to ASD and EF and found a relation between high polygenic score (PGS) for ASD and difficulties with behavior regulation aspects of EF in children and adolescents under assessment for ASD. Furthermore, high PGS for general intelligence was related to social problems. En ligne : http://dx.doi.org/10.1002/aur.2207 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420
in Autism Research > 13-2 (February 2020) . - p.207-220[article] Autism spectrum disorder polygenic scores are associated with every day executive function in children admitted for clinical assessment [Texte imprimé et/ou numérique] / Tonje TORSKE, Auteur ; Terje NAERLAND, Auteur ; Francesco BETTELLA, Auteur ; Thomas BJELLA, Auteur ; Eva MALT, Auteur ; Anne Lise HOYLAND, Auteur ; Nina STENBERG, Auteur ; Merete Glenne OIE, Auteur ; Ole A. ANDREASSEN, Auteur . - p.207-220.
Langues : Anglais (eng)
in Autism Research > 13-2 (February 2020) . - p.207-220
Mots-clés : attention deficit/hyperactivity disorder autism spectrum disorder behavior rating inventory of executive function executive function polygenic score Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDs) are behaviorally defined disorders with overlapping clinical features that are often associated with higher-order cognitive dysfunction, particularly executive dysfunction. Our aim was to determine if the polygenic score (PGS) for ASD is associated with parent-reported executive dysfunction in everyday life using the Behavior Rating Inventory of Executive Function (BRIEF). Furthermore, we investigated if PGS for general intelligence (INT) and attention deficit/hyperactivity disorder (ADHD) also correlate with BRIEF. We included 176 children, adolescents and young adults aged 5-22 years with full-scale intelligence quotient (IQ) above 70. All were admitted for clinical assessment of ASD symptoms and 68% obtained an ASD diagnosis. We found a significant difference between low and high ASD PGS groups in the BRIEF behavior regulation index (BRI) (P = 0.015, Cohen's d = 0.69). A linear regression model accounting for age, sex, full-scale IQ, Social Responsiveness Scale (SRS) total score, ASD, ADHD and INT PGS groups as well as genetic principal components, significantly predicted the BRI score; F(11,130) = 8.142, P < 0.001, R(2) = 0.41 (unadjusted). Only SRS total (P < 0.001), ASD PGS 0.1 group (P = 0.018), and sex (P = 0.022) made a significant contribution to the model. This suggests that the common ASD risk gene variants have a stronger association to behavioral regulation aspects of executive dysfunction than ADHD risk or INT variants in a clinical sample with ASD symptoms. Autism Res 2020, 13: 207-220. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: People with autism spectrum disorder (ASD) often have difficulties with higher-order cognitive processes that regulate thoughts and actions during goal-directed behavior, also known as executive function (EF). We studied the association between genetics related to ASD and EF and found a relation between high polygenic score (PGS) for ASD and difficulties with behavior regulation aspects of EF in children and adolescents under assessment for ASD. Furthermore, high PGS for general intelligence was related to social problems. En ligne : http://dx.doi.org/10.1002/aur.2207 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 Parsing Heterogeneity of Executive Function in Typically and Atypically Developing Children: A Conceptual Replication and Exploration of Social Function / Adriana C. BAEZ in Journal of Autism and Developmental Disorders, 50-3 (March 2020)
[article]
Titre : Parsing Heterogeneity of Executive Function in Typically and Atypically Developing Children: A Conceptual Replication and Exploration of Social Function Type de document : Texte imprimé et/ou numérique Auteurs : Adriana C. BAEZ, Auteur ; Dina R. DAJANI, Auteur ; Willa VOORHIES, Auteur ; Meaghan V. PARLADE, Auteur ; Michael ALESSANDRI, Auteur ; Jennifer C. BRITTON, Auteur ; Maria M. LLABRE, Auteur ; Lucina Q. UDDIN, Auteur Article en page(s) : p.707-718 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Behavior Rating Inventory of Executive Function Dimensional Latent profile analysis Index. décimale : PER Périodiques Résumé : Executive function (EF), the set of cognitive processes that govern goal-directed behavior, varies within developmental samples and clinical populations. Here, we perform a conceptual replication of prior work (Dajani et al. in Sci Rep 6:36566, 2016) in an independent sample of typically developing children (n = 183) and children with autism spectrum disorder (n = 104). Consistent with previous work, the latent profile analysis of parent-report EF measures provided evidence for three EF classes, which exhibited differential proportions of diagnostic groups. Additionally, children in the impaired EF group exhibited greater levels of social impairment. These results highlight the heterogeneity of EF ability among clinical and non-clinical populations and the link between EF and social abilities. En ligne : http://dx.doi.org/10.1007/s10803-019-04290-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419
in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.707-718[article] Parsing Heterogeneity of Executive Function in Typically and Atypically Developing Children: A Conceptual Replication and Exploration of Social Function [Texte imprimé et/ou numérique] / Adriana C. BAEZ, Auteur ; Dina R. DAJANI, Auteur ; Willa VOORHIES, Auteur ; Meaghan V. PARLADE, Auteur ; Michael ALESSANDRI, Auteur ; Jennifer C. BRITTON, Auteur ; Maria M. LLABRE, Auteur ; Lucina Q. UDDIN, Auteur . - p.707-718.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.707-718
Mots-clés : Autism spectrum disorder Behavior Rating Inventory of Executive Function Dimensional Latent profile analysis Index. décimale : PER Périodiques Résumé : Executive function (EF), the set of cognitive processes that govern goal-directed behavior, varies within developmental samples and clinical populations. Here, we perform a conceptual replication of prior work (Dajani et al. in Sci Rep 6:36566, 2016) in an independent sample of typically developing children (n = 183) and children with autism spectrum disorder (n = 104). Consistent with previous work, the latent profile analysis of parent-report EF measures provided evidence for three EF classes, which exhibited differential proportions of diagnostic groups. Additionally, children in the impaired EF group exhibited greater levels of social impairment. These results highlight the heterogeneity of EF ability among clinical and non-clinical populations and the link between EF and social abilities. En ligne : http://dx.doi.org/10.1007/s10803-019-04290-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419