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Résultat de la recherche
3 recherche sur le mot-clé 'behavioural'




Commentary: Networks of peers, genes, and explanations – reflections on Szekely et al. (2016) / Thomas G. O'CONNOR in Journal of Child Psychology and Psychiatry, 57-6 (June 2016)
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Titre : Commentary: Networks of peers, genes, and explanations – reflections on Szekely et al. (2016) Type de document : Texte imprimé et/ou numérique Auteurs : Thomas G. O'CONNOR, Auteur Article en page(s) : p.695-696 Langues : Anglais (eng) Mots-clés : Peer relationships phenotype genetics behavioural Index. décimale : PER Périodiques Résumé : Much has been learned about the origins and effects of peer relationships on the health and well-being of children, adolescents, and adults. This commentary on Szekely et al. examines the role of genetics research on peer relationships, and the arising methodological and conceptual questions. Research findings on the genetics of peer networks illustrate how genetic influences may shape complex and dynamic phenotypes. Equally complex is the application of these findings for theory and practice. En ligne : http://dx.doi.org/10.1111/jcpp.12536 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289
in Journal of Child Psychology and Psychiatry > 57-6 (June 2016) . - p.695-696[article] Commentary: Networks of peers, genes, and explanations – reflections on Szekely et al. (2016) [Texte imprimé et/ou numérique] / Thomas G. O'CONNOR, Auteur . - p.695-696.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-6 (June 2016) . - p.695-696
Mots-clés : Peer relationships phenotype genetics behavioural Index. décimale : PER Périodiques Résumé : Much has been learned about the origins and effects of peer relationships on the health and well-being of children, adolescents, and adults. This commentary on Szekely et al. examines the role of genetics research on peer relationships, and the arising methodological and conceptual questions. Research findings on the genetics of peer networks illustrate how genetic influences may shape complex and dynamic phenotypes. Equally complex is the application of these findings for theory and practice. En ligne : http://dx.doi.org/10.1111/jcpp.12536 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289 Editorial: Research Domain Criteria (RDoC): a new psychiatric nosology whose time has not yet come / Bradley S. PETERSON in Journal of Child Psychology and Psychiatry, 56-7 (July 2015)
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Titre : Editorial: Research Domain Criteria (RDoC): a new psychiatric nosology whose time has not yet come Type de document : Texte imprimé et/ou numérique Auteurs : Bradley S. PETERSON, Auteur Article en page(s) : p.719-722 Langues : Anglais (eng) Mots-clés : Nosology Research Domain Criteria (RDoC) Diagnostic and Statistical Manual (DSM) neural systems behavioural cognitive functions developmental trajectories Index. décimale : PER Périodiques Résumé : In developing new ways of classifying mental disorders, RDoC is developing a new nosology, a new way of dividing nature at its seams. Given the NIMH influence on research agendas across the world, this scientific agenda will have important consequences for researchers and clinicians worldwide. Defining discrete neural systems and the behavioral and cognitive functions they subserve is scientifically important. Understanding how these systems relate to clinical problems, patient suffering, and improved treatments has immense potential practical value for clinical care worldwide. This Editorial places the RDoC framework in context and then sets out a series of conceptual, empirical, and developmental challenges for RDoC. Together these challenges suggest that RDoC is premature as a nosology and, as currently implemented, risks being reified and overly rigid in its application. En ligne : http://dx.doi.org/10.1111/jcpp.12439 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.719-722[article] Editorial: Research Domain Criteria (RDoC): a new psychiatric nosology whose time has not yet come [Texte imprimé et/ou numérique] / Bradley S. PETERSON, Auteur . - p.719-722.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.719-722
Mots-clés : Nosology Research Domain Criteria (RDoC) Diagnostic and Statistical Manual (DSM) neural systems behavioural cognitive functions developmental trajectories Index. décimale : PER Périodiques Résumé : In developing new ways of classifying mental disorders, RDoC is developing a new nosology, a new way of dividing nature at its seams. Given the NIMH influence on research agendas across the world, this scientific agenda will have important consequences for researchers and clinicians worldwide. Defining discrete neural systems and the behavioral and cognitive functions they subserve is scientifically important. Understanding how these systems relate to clinical problems, patient suffering, and improved treatments has immense potential practical value for clinical care worldwide. This Editorial places the RDoC framework in context and then sets out a series of conceptual, empirical, and developmental challenges for RDoC. Together these challenges suggest that RDoC is premature as a nosology and, as currently implemented, risks being reified and overly rigid in its application. En ligne : http://dx.doi.org/10.1111/jcpp.12439 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 Unique prediction of developmental psychopathology from genetic and familial risk / Robert J. LOUGHNAN in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)
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Titre : Unique prediction of developmental psychopathology from genetic and familial risk Type de document : Texte imprimé et/ou numérique Auteurs : Robert J. LOUGHNAN, Auteur ; Clare E. PALMER, Auteur ; Carolina MAKOWSKI, Auteur ; Wesley K. THOMPSON, Auteur ; Deanna M. BARCH, Auteur ; Terry L. JERNIGAN, Auteur ; Anders M. DALE, Auteur ; Chun Chieh FAN, Auteur Article en page(s) : p.1631-1643 Langues : Anglais (eng) Mots-clés : Adolescent Humans Genetic Predisposition to Disease Longitudinal Studies Multifactorial Inheritance Psychopathology Attention Deficit Disorder with Hyperactivity/diagnosis Risk Factors Genetics behavioural family history Index. décimale : PER Périodiques Résumé : BACKGROUND: Early detection is critical for easing the rising burden of psychiatric disorders. However, the specificity of psychopathological measurements and genetic predictors is unclear among youth. METHODS: We measured associations between genetic risk for psychopathology (polygenic risk scores (PRS) and family history (FH) measures) and a wide range of behavioral measures in a large sample (n=5,204) of early adolescent participants (9-11 years) from the Adolescent Brain and Cognitive Development Study(SM) . Associations were measured both with and without accounting for shared variance across measures of genetic risk. RESULTS: When controlling for genetic risk for other psychiatric disorders, polygenic risk for problematic opioid use (POU) is uniquely associated with lower behavioral inhibition. Attention deficit hyperactivity disorder (ADHD), depression (DEP), and attempted suicide (SUIC) PRS shared many significant associations with externalizing, internalizing, and psychosis-related behaviors. However, when accounting for all measures of genetic and familial risk, these PRS also showed clear, unique patterns of association. Polygenic risk for ASD, BIP, and SCZ, and attempted suicide uniquely predicted variability in cognitive performance. FH accounted for unique variability in behavior above and beyond PRS and vice versa, with FH measures explaining a greater proportion of unique variability compared to the PRS. CONCLUSION: Our results indicate that, among youth, many behaviors show shared genetic influences; however, there is also specificity in the profile of emerging psychopathologies for individuals with high genetic risk for particular disorders. This may be useful for quantifying early, differential risk for psychopathology in development. En ligne : http://dx.doi.org/10.1111/jcpp.13649 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1631-1643[article] Unique prediction of developmental psychopathology from genetic and familial risk [Texte imprimé et/ou numérique] / Robert J. LOUGHNAN, Auteur ; Clare E. PALMER, Auteur ; Carolina MAKOWSKI, Auteur ; Wesley K. THOMPSON, Auteur ; Deanna M. BARCH, Auteur ; Terry L. JERNIGAN, Auteur ; Anders M. DALE, Auteur ; Chun Chieh FAN, Auteur . - p.1631-1643.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1631-1643
Mots-clés : Adolescent Humans Genetic Predisposition to Disease Longitudinal Studies Multifactorial Inheritance Psychopathology Attention Deficit Disorder with Hyperactivity/diagnosis Risk Factors Genetics behavioural family history Index. décimale : PER Périodiques Résumé : BACKGROUND: Early detection is critical for easing the rising burden of psychiatric disorders. However, the specificity of psychopathological measurements and genetic predictors is unclear among youth. METHODS: We measured associations between genetic risk for psychopathology (polygenic risk scores (PRS) and family history (FH) measures) and a wide range of behavioral measures in a large sample (n=5,204) of early adolescent participants (9-11 years) from the Adolescent Brain and Cognitive Development Study(SM) . Associations were measured both with and without accounting for shared variance across measures of genetic risk. RESULTS: When controlling for genetic risk for other psychiatric disorders, polygenic risk for problematic opioid use (POU) is uniquely associated with lower behavioral inhibition. Attention deficit hyperactivity disorder (ADHD), depression (DEP), and attempted suicide (SUIC) PRS shared many significant associations with externalizing, internalizing, and psychosis-related behaviors. However, when accounting for all measures of genetic and familial risk, these PRS also showed clear, unique patterns of association. Polygenic risk for ASD, BIP, and SCZ, and attempted suicide uniquely predicted variability in cognitive performance. FH accounted for unique variability in behavior above and beyond PRS and vice versa, with FH measures explaining a greater proportion of unique variability compared to the PRS. CONCLUSION: Our results indicate that, among youth, many behaviors show shared genetic influences; however, there is also specificity in the profile of emerging psychopathologies for individuals with high genetic risk for particular disorders. This may be useful for quantifying early, differential risk for psychopathology in development. En ligne : http://dx.doi.org/10.1111/jcpp.13649 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490