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Editorial: Research Domain Criteria (RDoC): a new psychiatric nosology whose time has not yet come / Bradley S. PETERSON in Journal of Child Psychology and Psychiatry, 56-7 (July 2015)
[article]
Titre : Editorial: Research Domain Criteria (RDoC): a new psychiatric nosology whose time has not yet come Type de document : Texte imprimé et/ou numérique Auteurs : Bradley S. PETERSON, Auteur Article en page(s) : p.719-722 Langues : Anglais (eng) Mots-clés : Nosology Research Domain Criteria (RDoC) Diagnostic and Statistical Manual (DSM) neural systems behavioural cognitive functions developmental trajectories Index. décimale : PER Périodiques Résumé : In developing new ways of classifying mental disorders, RDoC is developing a new nosology, a new way of dividing nature at its seams. Given the NIMH influence on research agendas across the world, this scientific agenda will have important consequences for researchers and clinicians worldwide. Defining discrete neural systems and the behavioral and cognitive functions they subserve is scientifically important. Understanding how these systems relate to clinical problems, patient suffering, and improved treatments has immense potential practical value for clinical care worldwide. This Editorial places the RDoC framework in context and then sets out a series of conceptual, empirical, and developmental challenges for RDoC. Together these challenges suggest that RDoC is premature as a nosology and, as currently implemented, risks being reified and overly rigid in its application. En ligne : http://dx.doi.org/10.1111/jcpp.12439 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.719-722[article] Editorial: Research Domain Criteria (RDoC): a new psychiatric nosology whose time has not yet come [Texte imprimé et/ou numérique] / Bradley S. PETERSON, Auteur . - p.719-722.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.719-722
Mots-clés : Nosology Research Domain Criteria (RDoC) Diagnostic and Statistical Manual (DSM) neural systems behavioural cognitive functions developmental trajectories Index. décimale : PER Périodiques Résumé : In developing new ways of classifying mental disorders, RDoC is developing a new nosology, a new way of dividing nature at its seams. Given the NIMH influence on research agendas across the world, this scientific agenda will have important consequences for researchers and clinicians worldwide. Defining discrete neural systems and the behavioral and cognitive functions they subserve is scientifically important. Understanding how these systems relate to clinical problems, patient suffering, and improved treatments has immense potential practical value for clinical care worldwide. This Editorial places the RDoC framework in context and then sets out a series of conceptual, empirical, and developmental challenges for RDoC. Together these challenges suggest that RDoC is premature as a nosology and, as currently implemented, risks being reified and overly rigid in its application. En ligne : http://dx.doi.org/10.1111/jcpp.12439 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 Editorial: The shape of the nosology to come in developmental psychopathology / Joel T. NIGG in Journal of Child Psychology and Psychiatry, 56-4 (April 2015)
[article]
Titre : Editorial: The shape of the nosology to come in developmental psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Joel T. NIGG, Auteur Article en page(s) : p.397-399 Langues : Anglais (eng) Mots-clés : Nosology developmental psychopathology shared biological dimensions RDoC Index. décimale : PER Périodiques Résumé : The field has embarked on an effort to better integrate neurobiological and psychological dimensions of functioning with putative psychopathological syndromes. If successful, this effort aims to be a turning point as impactful as the change, a century ago, away from the study of symptom dimensions and toward the study of psychopathological syndromes. New statistical and neurobiological methods and findings hold considerable promise in this regard, and several papers in the present issue underscore these ongoing and important new directions. For this proposed direction to succeed, however, three guiding principles are necessary. First, the syndromal approach must continue to be viewed as provisional, and not reified. Second, in contrast, individual dimensions of neurobiology, psychology, personality, or symptoms should not be decontextualized but considered in relation to other traits and dimensions, syndromal configurations. Major clinical syndromes cannot be ignored. Third, following the Kraepelian insights of a century ago in addition to the more recent insights of developmental psychopathlogy, trait and dimension aspects of psychopathology need to be understood in their developmental context. Whether an integrated dimensional-categorical-developmental understanding of psychopathology can be extended to the entire nosology or only parts of it remains to be seen. En ligne : http://dx.doi.org/10.1111/jcpp.12408 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.397-399[article] Editorial: The shape of the nosology to come in developmental psychopathology [Texte imprimé et/ou numérique] / Joel T. NIGG, Auteur . - p.397-399.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.397-399
Mots-clés : Nosology developmental psychopathology shared biological dimensions RDoC Index. décimale : PER Périodiques Résumé : The field has embarked on an effort to better integrate neurobiological and psychological dimensions of functioning with putative psychopathological syndromes. If successful, this effort aims to be a turning point as impactful as the change, a century ago, away from the study of symptom dimensions and toward the study of psychopathological syndromes. New statistical and neurobiological methods and findings hold considerable promise in this regard, and several papers in the present issue underscore these ongoing and important new directions. For this proposed direction to succeed, however, three guiding principles are necessary. First, the syndromal approach must continue to be viewed as provisional, and not reified. Second, in contrast, individual dimensions of neurobiology, psychology, personality, or symptoms should not be decontextualized but considered in relation to other traits and dimensions, syndromal configurations. Major clinical syndromes cannot be ignored. Third, following the Kraepelian insights of a century ago in addition to the more recent insights of developmental psychopathlogy, trait and dimension aspects of psychopathology need to be understood in their developmental context. Whether an integrated dimensional-categorical-developmental understanding of psychopathology can be extended to the entire nosology or only parts of it remains to be seen. En ligne : http://dx.doi.org/10.1111/jcpp.12408 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 Classification of Behaviorally Defined Disorders: Biology Versus the DSM / Isabelle RAPIN in Journal of Autism and Developmental Disorders, 44-10 (October 2014)
[article]
Titre : Classification of Behaviorally Defined Disorders: Biology Versus the DSM Type de document : Texte imprimé et/ou numérique Auteurs : Isabelle RAPIN, Auteur Article en page(s) : p.2661-2666 Langues : Anglais (eng) Mots-clés : Nosology DSM RDoC Behavioral classification Biologic classification Pathogenesis Index. décimale : PER Périodiques Résumé : Three levels of investigation underlie all biologically based attempts at classification of behaviorally defined developmental and psychiatric disorders: Level A, pseudo-categorical classification of mostly dimensional descriptions of behaviors and their disorders included in the 2013 American Psychiatric Association’s Fifth Edition of the Diagnostic and Statistical Manual (DSM-5); Level C, mostly categorical classification of genetic and environmental causes (etiologies) of Level A disorders; and Level B, the pathophysiologic—both categorical and dimensional—biologic mechanisms underlying Level A “diagnoses” which comprise hierarchically interacting molecular, cellular, and neural networks and major brain pathways orchestrated by Level C etiologies. Besides modest numbers of effective psychotropic medications and their derivatives, major advances in treatment have addressed the behavioral symptoms of Level A-defined developmental and psychiatric disorders. The National Institute of Mental Health proposes support for a new biologically based Research Domain Criteria (RDoC) classification; its goal is to apply to behaviorally defined Level A developmental and psychiatric disorders the biologically based Level C and Level B research strategies that have greatly accelerated treatment and prevention of medical disorders. It plans to supplement effective educational and behavioral symptom-based interventions with faster, more potent and specific biologic therapies and, hopefully, to discover how effective behavioral interventions alter brain function. This commentary raises the question of whether a hybrid nosology that maps biology onto behavior is attainable. At a minimum, such a nosologic effort requires greater in-depth and better informed dialog between investigators of behavior and biology than occurs typically, and more realistic communication of the implications of research results to the public. En ligne : http://dx.doi.org/10.1007/s10803-014-2127-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2661-2666[article] Classification of Behaviorally Defined Disorders: Biology Versus the DSM [Texte imprimé et/ou numérique] / Isabelle RAPIN, Auteur . - p.2661-2666.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2661-2666
Mots-clés : Nosology DSM RDoC Behavioral classification Biologic classification Pathogenesis Index. décimale : PER Périodiques Résumé : Three levels of investigation underlie all biologically based attempts at classification of behaviorally defined developmental and psychiatric disorders: Level A, pseudo-categorical classification of mostly dimensional descriptions of behaviors and their disorders included in the 2013 American Psychiatric Association’s Fifth Edition of the Diagnostic and Statistical Manual (DSM-5); Level C, mostly categorical classification of genetic and environmental causes (etiologies) of Level A disorders; and Level B, the pathophysiologic—both categorical and dimensional—biologic mechanisms underlying Level A “diagnoses” which comprise hierarchically interacting molecular, cellular, and neural networks and major brain pathways orchestrated by Level C etiologies. Besides modest numbers of effective psychotropic medications and their derivatives, major advances in treatment have addressed the behavioral symptoms of Level A-defined developmental and psychiatric disorders. The National Institute of Mental Health proposes support for a new biologically based Research Domain Criteria (RDoC) classification; its goal is to apply to behaviorally defined Level A developmental and psychiatric disorders the biologically based Level C and Level B research strategies that have greatly accelerated treatment and prevention of medical disorders. It plans to supplement effective educational and behavioral symptom-based interventions with faster, more potent and specific biologic therapies and, hopefully, to discover how effective behavioral interventions alter brain function. This commentary raises the question of whether a hybrid nosology that maps biology onto behavior is attainable. At a minimum, such a nosologic effort requires greater in-depth and better informed dialog between investigators of behavior and biology than occurs typically, and more realistic communication of the implications of research results to the public. En ligne : http://dx.doi.org/10.1007/s10803-014-2127-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 Comorbidity / Adrian ANGOLD in Journal of Child Psychology and Psychiatry, 40-1 (January 1999)
[article]
Titre : Comorbidity Type de document : Texte imprimé et/ou numérique Auteurs : Adrian ANGOLD, Auteur ; E. Jane COSTELLO, Auteur ; Alaattin ERKANLI, Auteur Année de publication : 1999 Article en page(s) : p.57-87 Langues : Anglais (eng) Mots-clés : Diagnosis comorbidity child adolescent nosology Index. décimale : PER Périodiques Résumé : We review recent research on the prevalence, causes, and effects of diagnostic comorbidity among the most common groups of child and adolescent psychiatric disorders; anxiety disorders, depressive disorders, attention deficit hyperactivity disorders, oppositional defiant and conduct disorders, and substance abuse. A meta-analysis of representative general population studies provides estimates of the strength of associations between pairs of disorders with narrower confidence intervals than have previously been available. Current evidence convincingly eliminates methodological factors as a major cause of comorbidity. We review the implications of comorbidity for understanding the development of psychopathology and for nosology. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124
in Journal of Child Psychology and Psychiatry > 40-1 (January 1999) . - p.57-87[article] Comorbidity [Texte imprimé et/ou numérique] / Adrian ANGOLD, Auteur ; E. Jane COSTELLO, Auteur ; Alaattin ERKANLI, Auteur . - 1999 . - p.57-87.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 40-1 (January 1999) . - p.57-87
Mots-clés : Diagnosis comorbidity child adolescent nosology Index. décimale : PER Périodiques Résumé : We review recent research on the prevalence, causes, and effects of diagnostic comorbidity among the most common groups of child and adolescent psychiatric disorders; anxiety disorders, depressive disorders, attention deficit hyperactivity disorders, oppositional defiant and conduct disorders, and substance abuse. A meta-analysis of representative general population studies provides estimates of the strength of associations between pairs of disorders with narrower confidence intervals than have previously been available. Current evidence convincingly eliminates methodological factors as a major cause of comorbidity. We review the implications of comorbidity for understanding the development of psychopathology and for nosology. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124 Annual Research Review: Impact of advances in genetics in understanding developmental psychopathology / Anjene M. ADDINGTON in Journal of Child Psychology and Psychiatry, 53-5 (May 2012)
[article]
Titre : Annual Research Review: Impact of advances in genetics in understanding developmental psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Anjene M. ADDINGTON, Auteur ; Judith RAPOPORT, Auteur Année de publication : 2012 Article en page(s) : p.510-518 Langues : Anglais (eng) Mots-clés : Developmental psychopathology genetics copy number variantspre-natal diagnosis nosology prevention Index. décimale : PER Périodiques Résumé : It was hoped that diagnostic guidelines for, and treatment of, child psychiatric disorders in DSM-5 would be informed by the wealth of clinical genetic research related to neurodevelopmental disorders. In spite of remarkable advances in genetic technology, this has not been the case. Candidate gene, genome-wide association, and rare copy number variant (CNV) studies have been carried out for attention-deficit/hyperactivity disorder (ADHD), Autism, Tourette’s Syndrome, and schizophrenia, with intriguing results, but environmental factors, incomplete penetrance, pleiotropy, and genetic heterogeneity, underlying any given phenotype have limited clinical translation. One promising approach may be the use of developmental brain imaging measures as more relevant phenotypes. This is particularly important, as subtle abnormalities in timing and expression of gene pathways underlying brain development may well link these disorders and be the ultimate target of treatments. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02478.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154
in Journal of Child Psychology and Psychiatry > 53-5 (May 2012) . - p.510-518[article] Annual Research Review: Impact of advances in genetics in understanding developmental psychopathology [Texte imprimé et/ou numérique] / Anjene M. ADDINGTON, Auteur ; Judith RAPOPORT, Auteur . - 2012 . - p.510-518.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 53-5 (May 2012) . - p.510-518
Mots-clés : Developmental psychopathology genetics copy number variantspre-natal diagnosis nosology prevention Index. décimale : PER Périodiques Résumé : It was hoped that diagnostic guidelines for, and treatment of, child psychiatric disorders in DSM-5 would be informed by the wealth of clinical genetic research related to neurodevelopmental disorders. In spite of remarkable advances in genetic technology, this has not been the case. Candidate gene, genome-wide association, and rare copy number variant (CNV) studies have been carried out for attention-deficit/hyperactivity disorder (ADHD), Autism, Tourette’s Syndrome, and schizophrenia, with intriguing results, but environmental factors, incomplete penetrance, pleiotropy, and genetic heterogeneity, underlying any given phenotype have limited clinical translation. One promising approach may be the use of developmental brain imaging measures as more relevant phenotypes. This is particularly important, as subtle abnormalities in timing and expression of gene pathways underlying brain development may well link these disorders and be the ultimate target of treatments. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02478.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154 Commentary: Critical considerations for studying low-functioning autism / Bhismadev CHAKRABARTI in Journal of Child Psychology and Psychiatry, 58-4 (April 2017)
PermalinkComparing the characteristics and outcomes of parent- and teacher-reported oppositional defiant disorder: findings from a national sample / J. MCNEILIS in Journal of Child Psychology and Psychiatry, 59-6 (June 2018)
PermalinkEditorial: Distinguishing between the challenges posed by surface and deep forms of heterogeneity to diagnostic systems: do we need a new approach to subtyping of child and adolescent psychiatric disorders / Edmund J. S. SONUGA-BARKE in Journal of Child Psychology and Psychiatry, 57-1 (January 2016)
PermalinkEvaluating social (pragmatic) communication disorder / William MANDY in Journal of Child Psychology and Psychiatry, 58-10 (October 2017)
PermalinkIn search of disorders: internalizing symptom networks in a large clinical sample / E. MCELROY in Journal of Child Psychology and Psychiatry, 60-8 (August 2019)
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