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Childhood trauma and cognitive functioning in individuals at clinical high risk (CHR) for psychosis / T. VELIKONJA in Development and Psychopathology, 33-1 (February 2021)
[article]
Titre : Childhood trauma and cognitive functioning in individuals at clinical high risk (CHR) for psychosis Type de document : Texte imprimé et/ou numérique Auteurs : T. VELIKONJA, Auteur ; E. VELTHORST, Auteur ; J. ZINBERG, Auteur ; Tyrone D. CANNON, Auteur ; Barbara A. CORNBLATT, Auteur ; Diana O. PERKINS, Auteur ; Kristin S. CADENHEAD, Auteur ; M. T. TSUANG, Auteur ; Jean ADDINGTON, Auteur ; S. W. WOODS, Auteur ; T. MCGLASHAN, Auteur ; D. H. MATHALON, Auteur ; W. STONE, Auteur ; M. KESHAVAN, Auteur ; L. SEIDMAN, Auteur ; Carrie E. BEARDEN, Auteur Article en page(s) : p.53-64 Langues : Anglais (eng) Mots-clés : childhood trauma clinical high risk nonsocial cognition psychosis social cognition Index. décimale : PER Périodiques Résumé : Evidence suggests that early trauma may have a negative effect on cognitive functioning in individuals with psychosis, yet the relationship between childhood trauma and cognition among those at clinical high risk (CHR) for psychosis remains unexplored. Our sample consisted of 626 CHR children and 279 healthy controls who were recruited as part of the North American Prodrome Longitudinal Study 2. Childhood trauma up to the age of 16 (psychological, physical, and sexual abuse, emotional neglect, and bullying) was assessed by using the Childhood Trauma and Abuse Scale. Multiple domains of cognition were measured at baseline and at the time of psychosis conversion, using standardized assessments. In the CHR group, there was a trend for better performance in individuals who reported a history of multiple types of childhood trauma compared with those with no/one type of trauma (Cohen d = 0.16). A history of multiple trauma types was not associated with greater cognitive change in CHR converters over time. Our findings tentatively suggest there may be different mechanisms that lead to CHR states. Individuals who are at clinical high risk who have experienced multiple types of childhood trauma may have more typically developing premorbid cognitive functioning than those who reported minimal trauma do. Further research is needed to unravel the complexity of factors underlying the development of at-risk states. En ligne : http://dx.doi.org/10.1017/s095457941900155x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442
in Development and Psychopathology > 33-1 (February 2021) . - p.53-64[article] Childhood trauma and cognitive functioning in individuals at clinical high risk (CHR) for psychosis [Texte imprimé et/ou numérique] / T. VELIKONJA, Auteur ; E. VELTHORST, Auteur ; J. ZINBERG, Auteur ; Tyrone D. CANNON, Auteur ; Barbara A. CORNBLATT, Auteur ; Diana O. PERKINS, Auteur ; Kristin S. CADENHEAD, Auteur ; M. T. TSUANG, Auteur ; Jean ADDINGTON, Auteur ; S. W. WOODS, Auteur ; T. MCGLASHAN, Auteur ; D. H. MATHALON, Auteur ; W. STONE, Auteur ; M. KESHAVAN, Auteur ; L. SEIDMAN, Auteur ; Carrie E. BEARDEN, Auteur . - p.53-64.
Langues : Anglais (eng)
in Development and Psychopathology > 33-1 (February 2021) . - p.53-64
Mots-clés : childhood trauma clinical high risk nonsocial cognition psychosis social cognition Index. décimale : PER Périodiques Résumé : Evidence suggests that early trauma may have a negative effect on cognitive functioning in individuals with psychosis, yet the relationship between childhood trauma and cognition among those at clinical high risk (CHR) for psychosis remains unexplored. Our sample consisted of 626 CHR children and 279 healthy controls who were recruited as part of the North American Prodrome Longitudinal Study 2. Childhood trauma up to the age of 16 (psychological, physical, and sexual abuse, emotional neglect, and bullying) was assessed by using the Childhood Trauma and Abuse Scale. Multiple domains of cognition were measured at baseline and at the time of psychosis conversion, using standardized assessments. In the CHR group, there was a trend for better performance in individuals who reported a history of multiple types of childhood trauma compared with those with no/one type of trauma (Cohen d = 0.16). A history of multiple trauma types was not associated with greater cognitive change in CHR converters over time. Our findings tentatively suggest there may be different mechanisms that lead to CHR states. Individuals who are at clinical high risk who have experienced multiple types of childhood trauma may have more typically developing premorbid cognitive functioning than those who reported minimal trauma do. Further research is needed to unravel the complexity of factors underlying the development of at-risk states. En ligne : http://dx.doi.org/10.1017/s095457941900155x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442 Annual Research Review: Rethinking childhood trauma-new research directions for measurement, study design and analytical strategies / Andrea DANESE in Journal of Child Psychology and Psychiatry, 61-3 (March 2020)
[article]
Titre : Annual Research Review: Rethinking childhood trauma-new research directions for measurement, study design and analytical strategies Type de document : Texte imprimé et/ou numérique Auteurs : Andrea DANESE, Auteur Article en page(s) : p.236-250 Langues : Anglais (eng) Mots-clés : Childhood trauma adverse childhood experiences childhood abuse childhood maltreatment childhood victimization Index. décimale : PER Périodiques Résumé : Childhood trauma is a key modifiable risk factor for psychopathology. Despite significant scientific advances, traumatised children still have poorer long-term outcomes than nontraumatised children. New research paradigms are, thus, needed. To this end, the review examines three dominant assumptions about measurement, design and analytical strategies. Current research warns against using prospective and retrospective measures of childhood trauma interchangeably; against interpreting cross-sectional differences in putative mediating mechanisms between adults with or without a history of childhood trauma as evidence of longitudinal changes from pre-trauma conditions; and against directly applying explanatory models of resilience or vulnerability to psychopathology in traumatised children to forecast individual risk in unseen cases. The warnings equally apply to research on broader measures of adverse childhood experiences (ACEs). Further research examining these assumptions can generate new insights on how to prevent childhood trauma and its detrimental effects. En ligne : http://dx.doi.org/10.1111/jcpp.13160 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.236-250[article] Annual Research Review: Rethinking childhood trauma-new research directions for measurement, study design and analytical strategies [Texte imprimé et/ou numérique] / Andrea DANESE, Auteur . - p.236-250.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.236-250
Mots-clés : Childhood trauma adverse childhood experiences childhood abuse childhood maltreatment childhood victimization Index. décimale : PER Périodiques Résumé : Childhood trauma is a key modifiable risk factor for psychopathology. Despite significant scientific advances, traumatised children still have poorer long-term outcomes than nontraumatised children. New research paradigms are, thus, needed. To this end, the review examines three dominant assumptions about measurement, design and analytical strategies. Current research warns against using prospective and retrospective measures of childhood trauma interchangeably; against interpreting cross-sectional differences in putative mediating mechanisms between adults with or without a history of childhood trauma as evidence of longitudinal changes from pre-trauma conditions; and against directly applying explanatory models of resilience or vulnerability to psychopathology in traumatised children to forecast individual risk in unseen cases. The warnings equally apply to research on broader measures of adverse childhood experiences (ACEs). Further research examining these assumptions can generate new insights on how to prevent childhood trauma and its detrimental effects. En ligne : http://dx.doi.org/10.1111/jcpp.13160 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 Effects of childhood trauma in psychopathy and response inhibition / Stacey A. BEDWELL in Development and Psychopathology, 35-2 (May 2023)
[article]
Titre : Effects of childhood trauma in psychopathy and response inhibition Type de document : Texte imprimé et/ou numérique Auteurs : Stacey A. BEDWELL, Auteur ; Charlotte HICKMAN, Auteur Article en page(s) : p.724-729 Langues : Anglais (eng) Mots-clés : childhood trauma executive function psychopathic traits psychopathy response inhibition Index. décimale : PER Périodiques Résumé : Childhood trauma is linked to impairments in executive function and working memory, thought to underly psychological disorders including depression and posttraumatic stress disorder. Research demonstrates that childhood trauma can partially mediate posttraumatic stress disorder in those with executive function deficits. Despite a link with executive function deficit, psychopathy as a consequence of trauma is yet to be studied in this context. The present study investigates the possibility of a relationship between childhood trauma, psychopathic traits, and response inhibition. Eighty participants were tasked to completed the Childhood Traumatic Events Scale (Pennebaker & Susman, 2013), Levenson?s Self-Report Psychopathy Scale (Levenson et al., 1995), and Flanker task of response inhibition (Eriksen & Eriksen, 1974). Scores of trauma exposure, psychopathic traits, and reaction times in the Flanker task were measured. Regression analysis revealed no significance for trauma exposure in predicting psychopathic traits (p = .201) and response inhibition (p = .183), indicating that childhood trauma does not strongly predict susceptibility to psychopathic traits or response inhibition deficits. These findings form an important basis on which to build a further understanding of the consequences of childhood trauma exposure, specifically in terms of understanding how specific cognitive functions may be influenced and providing a clearer understanding of how psychopathic traits develop. En ligne : http://dx.doi.org/10.1017/S0954579421001863 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504
in Development and Psychopathology > 35-2 (May 2023) . - p.724-729[article] Effects of childhood trauma in psychopathy and response inhibition [Texte imprimé et/ou numérique] / Stacey A. BEDWELL, Auteur ; Charlotte HICKMAN, Auteur . - p.724-729.
Langues : Anglais (eng)
in Development and Psychopathology > 35-2 (May 2023) . - p.724-729
Mots-clés : childhood trauma executive function psychopathic traits psychopathy response inhibition Index. décimale : PER Périodiques Résumé : Childhood trauma is linked to impairments in executive function and working memory, thought to underly psychological disorders including depression and posttraumatic stress disorder. Research demonstrates that childhood trauma can partially mediate posttraumatic stress disorder in those with executive function deficits. Despite a link with executive function deficit, psychopathy as a consequence of trauma is yet to be studied in this context. The present study investigates the possibility of a relationship between childhood trauma, psychopathic traits, and response inhibition. Eighty participants were tasked to completed the Childhood Traumatic Events Scale (Pennebaker & Susman, 2013), Levenson?s Self-Report Psychopathy Scale (Levenson et al., 1995), and Flanker task of response inhibition (Eriksen & Eriksen, 1974). Scores of trauma exposure, psychopathic traits, and reaction times in the Flanker task were measured. Regression analysis revealed no significance for trauma exposure in predicting psychopathic traits (p = .201) and response inhibition (p = .183), indicating that childhood trauma does not strongly predict susceptibility to psychopathic traits or response inhibition deficits. These findings form an important basis on which to build a further understanding of the consequences of childhood trauma exposure, specifically in terms of understanding how specific cognitive functions may be influenced and providing a clearer understanding of how psychopathic traits develop. En ligne : http://dx.doi.org/10.1017/S0954579421001863 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504 Cognitive mediators of the relationship between adverse childhood experiences and adult psychopathology: A systematic review / Katie AAFJES-VAN DOORN in Development and Psychopathology, 32-3 (August 2020)
[article]
Titre : Cognitive mediators of the relationship between adverse childhood experiences and adult psychopathology: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Katie AAFJES-VAN DOORN, Auteur ; Céline KAMSTEEG, Auteur ; George SILBERSCHATZ, Auteur Article en page(s) : p.1017-1029 Langues : Anglais (eng) Mots-clés : childhood trauma cognitive mediators psychopathology review Index. décimale : PER Périodiques Résumé : This is the first review to rigorously examine the mediating role of cognitive factors in the relationship between childhood trauma and subsequent adult psychopathology, and highlight areas for future research. A database search (Child Development & Adolescent Studies, ERIC, Global Health, PsycARTICLES, and PsycINFO) was conducted to identify empirical studies on cognitive factors, explaining the relationship between different types of adverse childhood experiences and adult psychopathology across clinical and nonclinical populations. A narrative synthesis and appraisal of the methodological quality of the studies was conducted. Ninety-eight mediation studies were identified, comprising 4,137 clinical and 28,228 nonclinical participants. Despite great variation in methodological quality of the studies, our narrative synthesis suggests that cognitive factors mediate the relationship between early trauma and later psychopathology. This finding is consistent across different measures of traumatic experiences, psychopathology, and cognitive mediators. Cognitive mediators represent potentially valuable intervention targets for (non)clinical patients who have experienced childhood adversity. Future studies are needed to (a) establish longitudinal causal connections, and (b) assess the effect of interventions that specifically target cognitive change in patients with different levels and types of pathology. En ligne : http://dx.doi.org/10.1017/s0954579419001317 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429
in Development and Psychopathology > 32-3 (August 2020) . - p.1017-1029[article] Cognitive mediators of the relationship between adverse childhood experiences and adult psychopathology: A systematic review [Texte imprimé et/ou numérique] / Katie AAFJES-VAN DOORN, Auteur ; Céline KAMSTEEG, Auteur ; George SILBERSCHATZ, Auteur . - p.1017-1029.
Langues : Anglais (eng)
in Development and Psychopathology > 32-3 (August 2020) . - p.1017-1029
Mots-clés : childhood trauma cognitive mediators psychopathology review Index. décimale : PER Périodiques Résumé : This is the first review to rigorously examine the mediating role of cognitive factors in the relationship between childhood trauma and subsequent adult psychopathology, and highlight areas for future research. A database search (Child Development & Adolescent Studies, ERIC, Global Health, PsycARTICLES, and PsycINFO) was conducted to identify empirical studies on cognitive factors, explaining the relationship between different types of adverse childhood experiences and adult psychopathology across clinical and nonclinical populations. A narrative synthesis and appraisal of the methodological quality of the studies was conducted. Ninety-eight mediation studies were identified, comprising 4,137 clinical and 28,228 nonclinical participants. Despite great variation in methodological quality of the studies, our narrative synthesis suggests that cognitive factors mediate the relationship between early trauma and later psychopathology. This finding is consistent across different measures of traumatic experiences, psychopathology, and cognitive mediators. Cognitive mediators represent potentially valuable intervention targets for (non)clinical patients who have experienced childhood adversity. Future studies are needed to (a) establish longitudinal causal connections, and (b) assess the effect of interventions that specifically target cognitive change in patients with different levels and types of pathology. En ligne : http://dx.doi.org/10.1017/s0954579419001317 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 Noradrenergic activation induced by yohimbine decreases interoceptive accuracy in healthy individuals with childhood adversity / André SCHULZ in Development and Psychopathology, 34-3 (August 2022)
[article]
Titre : Noradrenergic activation induced by yohimbine decreases interoceptive accuracy in healthy individuals with childhood adversity Type de document : Texte imprimé et/ou numérique Auteurs : André SCHULZ, Auteur ; Christian E. DEUTER, Auteur ; Ion-Hideo BREDEN, Auteur ; Claus VOGELE, Auteur ; Katja WINGENFELD, Auteur ; Christian OTTE, Auteur ; Linn K. KUEHL, Auteur Article en page(s) : p.1013-1024 Langues : Anglais (eng) Mots-clés : alpha2-adrenergic receptors childhood trauma interoception major depressive disorder stress Index. décimale : PER Périodiques Résumé : Acute stress affects interoception, but it remains unclear if this is due to activation of the sympatho-adreno-medullary (SAM) or hypothalamic “pituitary “adrenocortical axis. This study aimed to investigate the effect of SAM axis activation on interoceptive accuracy (IAcc). Central alpha2-adrenergic receptors represent a negative feedback mechanism of the SAM axis. Major depressive disorder and adverse childhood experiences (ACE) are associated with alterations in the biological stress systems, including central alpha2-adrenergic receptors. Here, healthy individuals with and without ACE as well as depressive patients with and without ACE (n = 114; all without antidepressant medication) were tested after yohimbine (alpha2-adrenergic antagonist) and placebo. We assessed IAcc and sensibility in a heartbeat counting task. Increases in systolic and diastolic blood pressure after yohimbine confirmed successful SAM axis activation. IAcc decreased after yohimbine only in the healthy group with ACE, but remained unchanged in all other groups (Group × Drug interaction). This effect may be due to selective upregulation of alpha2-adrenergic receptors after childhood trauma, which reduces capacity for attention focus on heartbeats. The sympathetic neural pathway including alpha2-adrenergic circuitries may be essential for mediating interoceptive signal transmission. Suppressed processing of physical sensations in stressful situations may represent an adaptive response in healthy individuals who experienced ACE. En ligne : http://dx.doi.org/10.1017/S0954579420001613 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485
in Development and Psychopathology > 34-3 (August 2022) . - p.1013-1024[article] Noradrenergic activation induced by yohimbine decreases interoceptive accuracy in healthy individuals with childhood adversity [Texte imprimé et/ou numérique] / André SCHULZ, Auteur ; Christian E. DEUTER, Auteur ; Ion-Hideo BREDEN, Auteur ; Claus VOGELE, Auteur ; Katja WINGENFELD, Auteur ; Christian OTTE, Auteur ; Linn K. KUEHL, Auteur . - p.1013-1024.
Langues : Anglais (eng)
in Development and Psychopathology > 34-3 (August 2022) . - p.1013-1024
Mots-clés : alpha2-adrenergic receptors childhood trauma interoception major depressive disorder stress Index. décimale : PER Périodiques Résumé : Acute stress affects interoception, but it remains unclear if this is due to activation of the sympatho-adreno-medullary (SAM) or hypothalamic “pituitary “adrenocortical axis. This study aimed to investigate the effect of SAM axis activation on interoceptive accuracy (IAcc). Central alpha2-adrenergic receptors represent a negative feedback mechanism of the SAM axis. Major depressive disorder and adverse childhood experiences (ACE) are associated with alterations in the biological stress systems, including central alpha2-adrenergic receptors. Here, healthy individuals with and without ACE as well as depressive patients with and without ACE (n = 114; all without antidepressant medication) were tested after yohimbine (alpha2-adrenergic antagonist) and placebo. We assessed IAcc and sensibility in a heartbeat counting task. Increases in systolic and diastolic blood pressure after yohimbine confirmed successful SAM axis activation. IAcc decreased after yohimbine only in the healthy group with ACE, but remained unchanged in all other groups (Group × Drug interaction). This effect may be due to selective upregulation of alpha2-adrenergic receptors after childhood trauma, which reduces capacity for attention focus on heartbeats. The sympathetic neural pathway including alpha2-adrenergic circuitries may be essential for mediating interoceptive signal transmission. Suppressed processing of physical sensations in stressful situations may represent an adaptive response in healthy individuals who experienced ACE. En ligne : http://dx.doi.org/10.1017/S0954579420001613 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 Research Review: Why do prospective and retrospective measures of maltreatment differ? A narrative review / Oonagh COLEMAN in Journal of Child Psychology and Psychiatry, 65-12 (December 2024)
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