19 recherche sur le mot-clé 'maternal sensitivity'

Maternal sensitivity and child internalizing and externalizing behavior: a mediating role for glucocorticoid receptor gene (NR3C1) methylation? / Roseriet BEIJERS ; Kieran J. O?DONNELL ; Carolina DE WEERTH ; Marieke S. TOLLENAAR in Development and Psychopathology, 36-2 (May 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-2 (May 2024) . - p.967-978 Titre : Maternal sensitivity and child internalizing and externalizing behavior: a mediating role for glucocorticoid receptor gene (NR3C1) methylation? Type de document : Texte imprimé et/ou numérique Auteurs : Roseriet BEIJERS, Auteur ; Kieran J. O?DONNELL, Auteur ; Carolina DE WEERTH, Auteur ; Marieke S. TOLLENAAR, Auteur Article en page(s) : p.967-978 Langues : Anglais (eng) Mots-clés : NR3C1  externalizing  internalizing  maternal sensitivity  methylation Index. décimale : PER Périodiques Résumé : The early caregiving environment can have lasting effects on child mental health. Animal models suggest that glucocorticoid receptor gene (NR3C1) DNA methylation plays a mediating role in linking more responsive caregiving to improved behavioral outcomes by its impact on the stress regulatory system. In this longitudinal study, we examined whether children?s NR3C1 methylation levels mediate an effect of maternal sensitivity in infancy on levels of child internalizing and externalizing behavior in a community sample. Maternal sensitivity of 145 mothers was rated at infant age 5 weeks, 12 months, and 30 months by observing mother-infant interactions. Buccal DNA methylation was assessed in the same children at age 6 years and maternal-reported internalizing and externalizing behavior was assessed at age 6 and 10 years. Higher sensitivity at age 5 weeks significantly predicted lower DNA methylation levels at two NR3C1 CpG loci, although methylation levels at these loci did not mediate an effect of maternal sensitivity on levels of child internalizing and externalizing behavior. Overall, the study provides evidence that maternal sensitivity in early infancy is associated with DNA methylation levels at loci involved in stress regulation, but the significance of this finding for child mental health remains unclear. En ligne : https://dx.doi.org/10.1017/S0954579423000226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528 [article] Maternal sensitivity and child internalizing and externalizing behavior: a mediating role for glucocorticoid receptor gene (NR3C1) methylation? [Texte imprimé et/ou numérique] / Roseriet BEIJERS, Auteur ; Kieran J. O?DONNELL, Auteur ; Carolina DE WEERTH, Auteur ; Marieke S. TOLLENAAR, Auteur . - p.967-978. Langues : Anglais (eng) in Development and Psychopathology > 36-2 (May 2024) . - p.967-978 Mots-clés : NR3C1  externalizing  internalizing  maternal sensitivity  methylation Index. décimale : PER Périodiques Résumé : The early caregiving environment can have lasting effects on child mental health. Animal models suggest that glucocorticoid receptor gene (NR3C1) DNA methylation plays a mediating role in linking more responsive caregiving to improved behavioral outcomes by its impact on the stress regulatory system. In this longitudinal study, we examined whether children?s NR3C1 methylation levels mediate an effect of maternal sensitivity in infancy on levels of child internalizing and externalizing behavior in a community sample. Maternal sensitivity of 145 mothers was rated at infant age 5 weeks, 12 months, and 30 months by observing mother-infant interactions. Buccal DNA methylation was assessed in the same children at age 6 years and maternal-reported internalizing and externalizing behavior was assessed at age 6 and 10 years. Higher sensitivity at age 5 weeks significantly predicted lower DNA methylation levels at two NR3C1 CpG loci, although methylation levels at these loci did not mediate an effect of maternal sensitivity on levels of child internalizing and externalizing behavior. Overall, the study provides evidence that maternal sensitivity in early infancy is associated with DNA methylation levels at loci involved in stress regulation, but the significance of this finding for child mental health remains unclear. En ligne : https://dx.doi.org/10.1017/S0954579423000226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528

Breastfeeding, brain activation to own infant cry, and maternal sensitivity / Pilyoung KIM in Journal of Child Psychology and Psychiatry, 52-8 (August 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-8 (August 2011) . - p.907-915 Titre : Breastfeeding, brain activation to own infant cry, and maternal sensitivity Type de document : Texte imprimé et/ou numérique Auteurs : Pilyoung KIM, Auteur ; Ruth FELDMAN, Auteur ; Linda C. MAYES, Auteur ; Virginia EICHER, Auteur ; Nancy THOMPSON, Auteur ; James F. LECKMAN, Auteur ; James E. SWAIN, Auteur Année de publication : 2011 Article en page(s) : p.907-915 Langues : Anglais (eng) Mots-clés : Breastfeeding  infancy  maternal sensitivity  mother–infant interaction  neuroimaging Index. décimale : PER Périodiques Résumé : Background:  Research points to the importance of breastfeeding for promoting close mother–infant contact and social-emotional development. Recent functional magnetic resonance imaging (fMRI) studies have identified brain regions related to maternal behaviors. However, little research has addressed the neurobiological mechanisms underlying the relationship between breastfeeding and maternal behavior in human mothers. We investigated the associations between breastfeeding, maternal brain response to own infant stimuli, and maternal sensitivity in the early postpartum. Methods:  Seventeen biological mothers of healthy infants participated in two matched groups according to feeding method – exclusive breastfeeding and exclusive formula-feeding at 2–4 weeks postpartum. fMRI scanning was conducted in the first postpartum month to examine maternal brain activation in response to her own baby’s cry versus control baby-cry. Dyadic interactions between mothers and infants at 3–4 months postpartum were videotaped in the home and blindly coded for maternal sensitivity. Results:  In the first postpartum month, breastfeeding mothers showed greater activations in the superior frontal gyrus, insula, precuneus, striatum, and amygdala while listening to their own baby-cry as compared to formula-feeding mothers. For both breastfeeding and formula-feeding mothers, greater activations in the right superior frontal gyrus and amygdala were associated with higher maternal sensitivity at 3–4 months postpartum. Conclusions:  Results suggest links between breastfeeding and greater response to infant cues in brain regions implicated in maternal–infant bonding and empathy during the early postpartum. Such brain activations may facilitate greater maternal sensitivity as infants enter their social world. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02406.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132 [article] Breastfeeding, brain activation to own infant cry, and maternal sensitivity [Texte imprimé et/ou numérique] / Pilyoung KIM, Auteur ; Ruth FELDMAN, Auteur ; Linda C. MAYES, Auteur ; Virginia EICHER, Auteur ; Nancy THOMPSON, Auteur ; James F. LECKMAN, Auteur ; James E. SWAIN, Auteur . - 2011 . - p.907-915. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-8 (August 2011) . - p.907-915 Mots-clés : Breastfeeding  infancy  maternal sensitivity  mother–infant interaction  neuroimaging Index. décimale : PER Périodiques Résumé : Background:  Research points to the importance of breastfeeding for promoting close mother–infant contact and social-emotional development. Recent functional magnetic resonance imaging (fMRI) studies have identified brain regions related to maternal behaviors. However, little research has addressed the neurobiological mechanisms underlying the relationship between breastfeeding and maternal behavior in human mothers. We investigated the associations between breastfeeding, maternal brain response to own infant stimuli, and maternal sensitivity in the early postpartum. Methods:  Seventeen biological mothers of healthy infants participated in two matched groups according to feeding method – exclusive breastfeeding and exclusive formula-feeding at 2–4 weeks postpartum. fMRI scanning was conducted in the first postpartum month to examine maternal brain activation in response to her own baby’s cry versus control baby-cry. Dyadic interactions between mothers and infants at 3–4 months postpartum were videotaped in the home and blindly coded for maternal sensitivity. Results:  In the first postpartum month, breastfeeding mothers showed greater activations in the superior frontal gyrus, insula, precuneus, striatum, and amygdala while listening to their own baby-cry as compared to formula-feeding mothers. For both breastfeeding and formula-feeding mothers, greater activations in the right superior frontal gyrus and amygdala were associated with higher maternal sensitivity at 3–4 months postpartum. Conclusions:  Results suggest links between breastfeeding and greater response to infant cues in brain regions implicated in maternal–infant bonding and empathy during the early postpartum. Such brain activations may facilitate greater maternal sensitivity as infants enter their social world. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02406.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132

Differential susceptibility effects of maternal sensitivity in childhood on small for gestational age adults' wealth / Tobey NICHOLS in Development and Psychopathology, 32-1 (February 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-1 (February 2020) . - p.197-203 Titre : Differential susceptibility effects of maternal sensitivity in childhood on small for gestational age adults' wealth Type de document : Texte imprimé et/ou numérique Auteurs : Tobey NICHOLS, Auteur ; Julia JAEKEL, Auteur ; Peter BARTMANN, Auteur ; Dieter WOLKE, Auteur Article en page(s) : p.197-203 Langues : Anglais (eng) Mots-clés : Bavarian Longitudinal Study (BLS)  differential susceptibility  maternal sensitivity  small for gestational age  wealth Index. décimale : PER Périodiques Résumé : Being born small for gestational age (SGA) is considered a developmental vulnerability. Alternatively, SGA may be viewed as a marker for individual susceptibility to environmental experiences. The aim was to test if individuals born SGA are more susceptible to both negative and positive environmental experiences assessed by sensitive parenting in childhood compared with those born appropriate for gestational age (AGA). The target outcome was wealth in young adulthood. A total of 438 participants (SGA, n = 109; AGA, n = 329) were studied as part of the prospective Bavarian Longitudinal Study of neonatal at-risk children. Maternal sensitivity was observed during a standardized mother-child interaction task, and IQ was assessed with the Kaufman Assessment Battery for Children at age 6 years. At age 26, participants' wealth was assessed with a comprehensive composite score. Individuals born SGA were found to be more susceptible to the effects of sensitive parenting after controlling for gestational age and IQ at age 6 years. When maternal sensitivity was lower than average, SGA adults did worse than AGA adults, but when exposed to above-average maternal sensitivity in childhood, they obtained significantly higher wealth than their AGA peers by 26 years of age. En ligne : http://dx.doi.org/10.1017/s0954579418001669 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416 [article] Differential susceptibility effects of maternal sensitivity in childhood on small for gestational age adults' wealth [Texte imprimé et/ou numérique] / Tobey NICHOLS, Auteur ; Julia JAEKEL, Auteur ; Peter BARTMANN, Auteur ; Dieter WOLKE, Auteur . - p.197-203. Langues : Anglais (eng) in Development and Psychopathology > 32-1 (February 2020) . - p.197-203 Mots-clés : Bavarian Longitudinal Study (BLS)  differential susceptibility  maternal sensitivity  small for gestational age  wealth Index. décimale : PER Périodiques Résumé : Being born small for gestational age (SGA) is considered a developmental vulnerability. Alternatively, SGA may be viewed as a marker for individual susceptibility to environmental experiences. The aim was to test if individuals born SGA are more susceptible to both negative and positive environmental experiences assessed by sensitive parenting in childhood compared with those born appropriate for gestational age (AGA). The target outcome was wealth in young adulthood. A total of 438 participants (SGA, n = 109; AGA, n = 329) were studied as part of the prospective Bavarian Longitudinal Study of neonatal at-risk children. Maternal sensitivity was observed during a standardized mother-child interaction task, and IQ was assessed with the Kaufman Assessment Battery for Children at age 6 years. At age 26, participants' wealth was assessed with a comprehensive composite score. Individuals born SGA were found to be more susceptible to the effects of sensitive parenting after controlling for gestational age and IQ at age 6 years. When maternal sensitivity was lower than average, SGA adults did worse than AGA adults, but when exposed to above-average maternal sensitivity in childhood, they obtained significantly higher wealth than their AGA peers by 26 years of age. En ligne : http://dx.doi.org/10.1017/s0954579418001669 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416

A DRD4 gene by maternal sensitivity interaction predicts risk for overweight or obesity in two independent cohorts of preschool children / Robert D. LEVITAN in Journal of Child Psychology and Psychiatry, 58-2 (February 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-2 (February 2017) . - p.180-188 Titre : A DRD4 gene by maternal sensitivity interaction predicts risk for overweight or obesity in two independent cohorts of preschool children Type de document : Texte imprimé et/ou numérique Auteurs : Robert D. LEVITAN, Auteur ; Pauline JANSEN, Auteur ; Barbara WENDLAND, Auteur ; Henning TIEMEIER, Auteur ; Vincent W.V. JADDOE, Auteur ; Patricia P. SILVEIRA, Auteur ; James L. KENNEDY, Auteur ; Leslie ATKINSON, Auteur ; Alison FLEMING, Auteur ; Marla SOKOLOWSKI, Auteur ; Helene GAUDREAU, Auteur ; Meir STEINER, Auteur ; Laurette DUBE, Auteur ; Jill HAMILTON, Auteur ; Ellen MOSS, Auteur ; Ashley WAZANA, Auteur ; Michael MEANEY, Auteur Année de publication : 2017 Article en page(s) : p.180-188 Langues : Anglais (eng) Mots-clés : Maternal sensitivity  DRD4  obesity  sex differences Index. décimale : PER Périodiques Résumé : Background Recent evidence suggests that early exposure to low maternal sensitivity is a risk factor for obesity in children and adolescents. A separate line of study shows that the seven-repeat (7R) allele of the dopamine-4 receptor gene (DRD4) increases susceptibility to environmental factors including maternal sensitivity. The current study integrates these lines of work by examining whether preschoolers carrying the 7R allele are more vulnerable to low maternal sensitivity as it relates to overweight/obesity risk. Method The Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project in Canada was used as the discovery cohort (N = 203), while the Generation R study in the Netherlands was used as a replication sample (N = 270). Regression models to predict both continuous BMI z-scores and membership in any higher BMI category based on established World Health Organization (WHO) cutoffs for 48 months of age were completed. Results In both cohorts, there was a significant maternal sensitivity by DRD4 by sex interaction predicting higher body mass indices and/or obesity risk. As hypothesized, post hoc testing revealed an inverse relationship between maternal sensitivity and body mass indices in 7R allele carriers relative to noncarriers. This finding was strongest in girls in the Canadian cohort and in boys in the Dutch cohort. Conclusions Many children who carry the 7R allele of DRD4 appear to be more influenced by maternal sensitivity as it relates to overweight/obesity risk, consistent with a plasticity effect. Given the relatively small sample sizes available for these analyses, further replications will be needed to confirm and extend these results. En ligne : http://dx.doi.org/10.1111/jcpp.12646 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=299 [article] A DRD4 gene by maternal sensitivity interaction predicts risk for overweight or obesity in two independent cohorts of preschool children [Texte imprimé et/ou numérique] / Robert D. LEVITAN, Auteur ; Pauline JANSEN, Auteur ; Barbara WENDLAND, Auteur ; Henning TIEMEIER, Auteur ; Vincent W.V. JADDOE, Auteur ; Patricia P. SILVEIRA, Auteur ; James L. KENNEDY, Auteur ; Leslie ATKINSON, Auteur ; Alison FLEMING, Auteur ; Marla SOKOLOWSKI, Auteur ; Helene GAUDREAU, Auteur ; Meir STEINER, Auteur ; Laurette DUBE, Auteur ; Jill HAMILTON, Auteur ; Ellen MOSS, Auteur ; Ashley WAZANA, Auteur ; Michael MEANEY, Auteur . - 2017 . - p.180-188. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-2 (February 2017) . - p.180-188 Mots-clés : Maternal sensitivity  DRD4  obesity  sex differences Index. décimale : PER Périodiques Résumé : Background Recent evidence suggests that early exposure to low maternal sensitivity is a risk factor for obesity in children and adolescents. A separate line of study shows that the seven-repeat (7R) allele of the dopamine-4 receptor gene (DRD4) increases susceptibility to environmental factors including maternal sensitivity. The current study integrates these lines of work by examining whether preschoolers carrying the 7R allele are more vulnerable to low maternal sensitivity as it relates to overweight/obesity risk. Method The Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project in Canada was used as the discovery cohort (N = 203), while the Generation R study in the Netherlands was used as a replication sample (N = 270). Regression models to predict both continuous BMI z-scores and membership in any higher BMI category based on established World Health Organization (WHO) cutoffs for 48 months of age were completed. Results In both cohorts, there was a significant maternal sensitivity by DRD4 by sex interaction predicting higher body mass indices and/or obesity risk. As hypothesized, post hoc testing revealed an inverse relationship between maternal sensitivity and body mass indices in 7R allele carriers relative to noncarriers. This finding was strongest in girls in the Canadian cohort and in boys in the Dutch cohort. Conclusions Many children who carry the 7R allele of DRD4 appear to be more influenced by maternal sensitivity as it relates to overweight/obesity risk, consistent with a plasticity effect. Given the relatively small sample sizes available for these analyses, further replications will be needed to confirm and extend these results. En ligne : http://dx.doi.org/10.1111/jcpp.12646 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=299

Early processing (N170) of infant faces in mothers of children with autism spectrum disorder and its association with maternal sensitivity / C. MARQUEZ in Autism Research, 12-5 (May 2019)  

Public ISBD [article]  inAutism Research > 12-5 (May 2019) . - p.744-758 Titre : Early processing (N170) of infant faces in mothers of children with autism spectrum disorder and its association with maternal sensitivity Type de document : Texte imprimé et/ou numérique Auteurs : C. MARQUEZ, Auteur ; H. NICOLINI, Auteur ; M. J. CROWLEY, Auteur ; R. SOLIS-VIVANCO, Auteur Article en page(s) : p.744-758 Langues : Anglais (eng) Mots-clés : N170  autism spectrum disorder  event-related potential  infant face processing  maternal sensitivity  mothers Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) exhibit impaired adult facial processing, as shown by the N170 event-related potential. However, few studies explore such processing in mothers of children with ASD, and none has assessed the early processing of infant faces in these women. Moreover, whether processing of infant facial expressions in mothers of children with ASD is related to their response to their child's needs (maternal sensitivity [MS]) remains unknown. This study explored the N170 related to infant faces in a group of mothers of children with ASD (MA) and a reference group of mothers of children without ASD. For both emotional (crying, smiling) and neutral expressions, the MA group exhibited larger amplitudes of N170 in the right hemisphere, while the reference group showed similar interhemispheric amplitudes. This lateralization effect within the MA group was not present for nonfaces and was stronger in the mothers with higher MS. We propose that mothers of ASD children use specialized perceptual resources to process infant faces, and this specialization is mediated by MS. Our findings suggest that having an ASD child modulates mothers' early neurophysiological responsiveness to infant cues. Whether this modulation represents a biological marker or a response given by experience remains to be explored. Autism Research 2019, 12: 744-758. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: When mothers of children with autism spectrum disorder (ASD) see baby faces expressing emotions, they show a right-sided electrical response in the brain. This lateralization was stronger in mothers who were more sensitive to their children's needs. We conclude that having a child with ASD and being more attuned to their behavior generates a specialized pattern of brain activity when processing infant faces. Whether this pattern is biological or given by experience remains to be explored. En ligne : http://dx.doi.org/10.1002/aur.2102 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=397 [article] Early processing (N170) of infant faces in mothers of children with autism spectrum disorder and its association with maternal sensitivity [Texte imprimé et/ou numérique] / C. MARQUEZ, Auteur ; H. NICOLINI, Auteur ; M. J. CROWLEY, Auteur ; R. SOLIS-VIVANCO, Auteur . - p.744-758. Langues : Anglais (eng) in Autism Research > 12-5 (May 2019) . - p.744-758 Mots-clés : N170  autism spectrum disorder  event-related potential  infant face processing  maternal sensitivity  mothers Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) exhibit impaired adult facial processing, as shown by the N170 event-related potential. However, few studies explore such processing in mothers of children with ASD, and none has assessed the early processing of infant faces in these women. Moreover, whether processing of infant facial expressions in mothers of children with ASD is related to their response to their child's needs (maternal sensitivity [MS]) remains unknown. This study explored the N170 related to infant faces in a group of mothers of children with ASD (MA) and a reference group of mothers of children without ASD. For both emotional (crying, smiling) and neutral expressions, the MA group exhibited larger amplitudes of N170 in the right hemisphere, while the reference group showed similar interhemispheric amplitudes. This lateralization effect within the MA group was not present for nonfaces and was stronger in the mothers with higher MS. We propose that mothers of ASD children use specialized perceptual resources to process infant faces, and this specialization is mediated by MS. Our findings suggest that having an ASD child modulates mothers' early neurophysiological responsiveness to infant cues. Whether this modulation represents a biological marker or a response given by experience remains to be explored. Autism Research 2019, 12: 744-758. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: When mothers of children with autism spectrum disorder (ASD) see baby faces expressing emotions, they show a right-sided electrical response in the brain. This lateralization was stronger in mothers who were more sensitive to their children's needs. We conclude that having a child with ASD and being more attuned to their behavior generates a specialized pattern of brain activity when processing infant faces. Whether this pattern is biological or given by experience remains to be explored. En ligne : http://dx.doi.org/10.1002/aur.2102 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=397

Effects of maternal sensitivity on low birth weight children's academic achievement: a test of differential susceptibility versus diathesis stress / Julia JAEKEL in Journal of Child Psychology and Psychiatry, 56-6 (June 2015)  

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Evidence for interplay between genes and parenting on infant temperament in the first year of life: monoamine oxidase A polymorphism moderates effects of maternal sensitivity on infant anger proneness / Andrew PICKLES in Journal of Child Psychology and Psychiatry, 54-12 (December 2013)  

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Maternal symptoms of depression and sensitivity mediate the relation between maternal history of early adversity and her child temperament: The inheritance of circumstance / Andrée-Anne BOUVETTE-TURCOT in Development and Psychopathology, 32-2 (May 2020)  

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Profiles of early family environments and the growth of executive function: Maternal sensitivity as a protective factor / Seulki KU in Development and Psychopathology, 35-1 (February 2023)  

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Resolution of the child’s ASD diagnosis among Arab–Israeli mothers: Associations with maternal sensitivity and wellbeing / Smadar DOLEV in Research in Autism Spectrum Disorders, 21 (January 2016)  

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