6 recherche sur le mot-clé 'subtyping'

Subtyping the Autism Spectrum Disorder: Comparison of Children with High Functioning Autism and Asperger Syndrome / C. DE GIAMBATTISTA in Journal of Autism and Developmental Disorders, 49-1 (January 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.138-150 Titre : Subtyping the Autism Spectrum Disorder: Comparison of Children with High Functioning Autism and Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : C. DE GIAMBATTISTA, Auteur ; P. VENTURA, Auteur ; P. TREROTOLI, Auteur ; M. MARGARI, Auteur ; R. PALUMBI, Auteur ; L. MARGARI, Auteur Article en page(s) : p.138-150 Langues : Anglais (eng) Mots-clés : Asperger syndrome  Autism spectrum disorders  Dsm-5  High functioning autism  Subtyping Index. décimale : PER Périodiques Résumé : Since Hans Asperger's first description (Arch Psych Nervenkrankh 117:76-136, 1944), through Lorna Wing's translation and definition (Psychol Med 11:115-129, 1981), to its introduction in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM, 1994), Asperger Syndrome has always aroused huge interest and debate, until vanishing in the DSM fifth edition (2013). The debate regarded its diagnostic validity and its differentiation from high functioning autism (HFA). The present study aimed to examine whether AS differed from HFA in clinical profiles and to analyze the impact of DSM-5's innovation. Differences in cognitive, language, school functioning and comorbidities, were revealed when 80 AS and 70 HFA patients (3-18 years) were compared. Results suggested that an AS empirical distinction within autism spectrum disorder should be clinically useful. En ligne : http://dx.doi.org/10.1007/s10803-018-3689-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376 [article] Subtyping the Autism Spectrum Disorder: Comparison of Children with High Functioning Autism and Asperger Syndrome [Texte imprimé et/ou numérique] / C. DE GIAMBATTISTA, Auteur ; P. VENTURA, Auteur ; P. TREROTOLI, Auteur ; M. MARGARI, Auteur ; R. PALUMBI, Auteur ; L. MARGARI, Auteur . - p.138-150. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.138-150 Mots-clés : Asperger syndrome  Autism spectrum disorders  Dsm-5  High functioning autism  Subtyping Index. décimale : PER Périodiques Résumé : Since Hans Asperger's first description (Arch Psych Nervenkrankh 117:76-136, 1944), through Lorna Wing's translation and definition (Psychol Med 11:115-129, 1981), to its introduction in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM, 1994), Asperger Syndrome has always aroused huge interest and debate, until vanishing in the DSM fifth edition (2013). The debate regarded its diagnostic validity and its differentiation from high functioning autism (HFA). The present study aimed to examine whether AS differed from HFA in clinical profiles and to analyze the impact of DSM-5's innovation. Differences in cognitive, language, school functioning and comorbidities, were revealed when 80 AS and 70 HFA patients (3-18 years) were compared. Results suggested that an AS empirical distinction within autism spectrum disorder should be clinically useful. En ligne : http://dx.doi.org/10.1007/s10803-018-3689-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376

Data-driven dissection of the fever effect in autism spectrum disorder / Efrat Muller in Autism Research, 16-6 (June 2023)  

Public ISBD [article]  inAutism Research > 16-6 (June 2023) . - p.1225-1235 Titre : Data-driven dissection of the fever effect in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Efrat Muller, Auteur ; Ido SHALEV, Auteur ; Eitan Bachmat, Auteur ; Alal ERAN, Auteur Article en page(s) : p.1225-1235 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  fever effect  fever response  machine learning  Simons simplex collection  subtyping Index. décimale : PER Périodiques Résumé : Abstract Some individuals with autism spectrum disorder (ASD) demonstrate marked behavioral improvements during febrile episodes, in what is perhaps the only present-day means of modulating the core ASD phenotype. Understanding the nature of this so-called fever effect is therefore essential for leveraging this natural temporary relief of symptoms to a sustained efficacious intervention. Toward this goal, we used machine learning to analyze the rich clinical data of the Simons Simplex Collection, in which one out of every six children with ASD was reported to improve during febrile episodes, across multiple ASD domains. Reported behavioral improvements during febrile episodes were associated with maternal infection in pregnancy (OR?=?1.7, 95% CI?=?[1.42, 2.03], P?=?4.24???10?4) and gastrointestinal (GI) dysfunction (OR?=?1.46, 95% CI?=?[1.15, 1.81], P?=?1.94???10?3). Family members of children reported to improve when febrile have an increased prevalence of autoimmune disorders (OR?=?1.43, 95% CI?=?[1.23, 1.67], P?=?3.0???10?6), language disorders (OR?=?1.63, 95% CI?=?[1.29, 2.04], P?=?2.5???10?5), and neuropsychiatric disorders (OR?=?1.59, 95% CI?=?[1.34, 1.89], P? En ligne : https://doi.org/10.1002/aur.2935 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507 [article] Data-driven dissection of the fever effect in autism spectrum disorder [Texte imprimé et/ou numérique] / Efrat Muller, Auteur ; Ido SHALEV, Auteur ; Eitan Bachmat, Auteur ; Alal ERAN, Auteur . - p.1225-1235. Langues : Anglais (eng) in Autism Research > 16-6 (June 2023) . - p.1225-1235 Mots-clés : autism spectrum disorder  fever effect  fever response  machine learning  Simons simplex collection  subtyping Index. décimale : PER Périodiques Résumé : Abstract Some individuals with autism spectrum disorder (ASD) demonstrate marked behavioral improvements during febrile episodes, in what is perhaps the only present-day means of modulating the core ASD phenotype. Understanding the nature of this so-called fever effect is therefore essential for leveraging this natural temporary relief of symptoms to a sustained efficacious intervention. Toward this goal, we used machine learning to analyze the rich clinical data of the Simons Simplex Collection, in which one out of every six children with ASD was reported to improve during febrile episodes, across multiple ASD domains. Reported behavioral improvements during febrile episodes were associated with maternal infection in pregnancy (OR?=?1.7, 95% CI?=?[1.42, 2.03], P?=?4.24???10?4) and gastrointestinal (GI) dysfunction (OR?=?1.46, 95% CI?=?[1.15, 1.81], P?=?1.94???10?3). Family members of children reported to improve when febrile have an increased prevalence of autoimmune disorders (OR?=?1.43, 95% CI?=?[1.23, 1.67], P?=?3.0???10?6), language disorders (OR?=?1.63, 95% CI?=?[1.29, 2.04], P?=?2.5???10?5), and neuropsychiatric disorders (OR?=?1.59, 95% CI?=?[1.34, 1.89], P? En ligne : https://doi.org/10.1002/aur.2935 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=507

Heterogeneity in caregiving-related early adversity: Creating stable dimensions and subtypes / Aki NIKOLAIDIS in Development and Psychopathology, 34-2 (May 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-2 (May 2022) . - 621-634 Titre : Heterogeneity in caregiving-related early adversity: Creating stable dimensions and subtypes Type de document : Texte imprimé et/ou numérique Auteurs : Aki NIKOLAIDIS, Auteur ; Charlotte HELENIAK, Auteur ; Andrea FIELDS, Auteur ; Paul A. BLOOM, Auteur ; Michelle VANTIEGHEM, Auteur ; Anna VANNUCCI, Auteur ; Nicolas L. CAMACHO, Auteur ; Tricia CHOY, Auteur ; Lisa GIBSON, Auteur ; Chelsea HARMON, Auteur ; Syntia S. HADIS, Auteur ; Ian J. DOUGLAS, Auteur ; Michael P. MILHAM, Auteur ; Nim TOTTENHAM, Auteur Article en page(s) : 621-634 Langues : Anglais (eng) Mots-clés : caregiving related early adversities  heterogeneity  prediction  subtyping Index. décimale : PER Périodiques Résumé : Early psychosocial adversities exist at many levels, including caregiving-related, extrafamilial, and sociodemographic, which despite their high interrelatedness may have unique impacts on development. In this paper, we focus on caregiving-related early adversities (crEAs) and parse the heterogeneity of crEAs via data reduction techniques that identify experiential cooccurrences. Using network science, we characterized crEA cooccurrences to represent the comorbidity of crEA experiences across a sample of school-age children (n = 258; 6?12 years old) with a history of crEAs. crEA dimensions (variable level) and crEA subtypes (subject level) were identified using parallel factor analysis/principal component analysis and graph-based Louvain community detection. Bagging enhancement with cross-validation provided estimates of robustness. These data-driven dimensions/subtypes showed evidence of stability, transcended traditional sociolegally defined groups, were more homogenous than sociolegally defined groups, and reduced statistical correlations with sociodemographic factors. Finally, random forests showed both unique and common predictive importance of the crEA dimensions/subtypes for childhood mental health symptoms and academic skills. These data-driven outcomes provide additional tools and recommendations for crEA data reduction to inform precision medicine efforts in this area. En ligne : http://dx.doi.org/10.1017/s0954579421001668 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Heterogeneity in caregiving-related early adversity: Creating stable dimensions and subtypes [Texte imprimé et/ou numérique] / Aki NIKOLAIDIS, Auteur ; Charlotte HELENIAK, Auteur ; Andrea FIELDS, Auteur ; Paul A. BLOOM, Auteur ; Michelle VANTIEGHEM, Auteur ; Anna VANNUCCI, Auteur ; Nicolas L. CAMACHO, Auteur ; Tricia CHOY, Auteur ; Lisa GIBSON, Auteur ; Chelsea HARMON, Auteur ; Syntia S. HADIS, Auteur ; Ian J. DOUGLAS, Auteur ; Michael P. MILHAM, Auteur ; Nim TOTTENHAM, Auteur . - 621-634. Langues : Anglais (eng) in Development and Psychopathology > 34-2 (May 2022) . - 621-634 Mots-clés : caregiving related early adversities  heterogeneity  prediction  subtyping Index. décimale : PER Périodiques Résumé : Early psychosocial adversities exist at many levels, including caregiving-related, extrafamilial, and sociodemographic, which despite their high interrelatedness may have unique impacts on development. In this paper, we focus on caregiving-related early adversities (crEAs) and parse the heterogeneity of crEAs via data reduction techniques that identify experiential cooccurrences. Using network science, we characterized crEA cooccurrences to represent the comorbidity of crEA experiences across a sample of school-age children (n = 258; 6?12 years old) with a history of crEAs. crEA dimensions (variable level) and crEA subtypes (subject level) were identified using parallel factor analysis/principal component analysis and graph-based Louvain community detection. Bagging enhancement with cross-validation provided estimates of robustness. These data-driven dimensions/subtypes showed evidence of stability, transcended traditional sociolegally defined groups, were more homogenous than sociolegally defined groups, and reduced statistical correlations with sociodemographic factors. Finally, random forests showed both unique and common predictive importance of the crEA dimensions/subtypes for childhood mental health symptoms and academic skills. These data-driven outcomes provide additional tools and recommendations for crEA data reduction to inform precision medicine efforts in this area. En ligne : http://dx.doi.org/10.1017/s0954579421001668 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Heterogeneity in caregiving-related early adversity: Creating stable dimensions and subtypes - CORRIGENDUM / Aki NIKOLAIDIS in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1570-1570 Titre : Heterogeneity in caregiving-related early adversity: Creating stable dimensions and subtypes - CORRIGENDUM Type de document : Texte imprimé et/ou numérique Auteurs : Aki NIKOLAIDIS, Auteur ; Charlotte HELENIAK, Auteur ; Andrea FIELDS, Auteur ; Paul A. BLOOM, Auteur ; Michelle VANTIEGHEM, Auteur ; Anna VANNUCCI, Auteur ; Nicolas L. CAMACHO, Auteur ; Tricia CHOY, Auteur ; Lisa GIBSON, Auteur ; Chelsea HARMON, Auteur ; Syntia S. HADIS, Auteur ; Ian J. DOUGLAS, Auteur ; Michael P. MILHAM, Auteur ; Nim TOTTENHAM, Auteur Article en page(s) : p.1570-1570 Langues : Anglais (eng) Mots-clés : caregiving related early adversities  heterogeneity  prediction  subtyping Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579422000529 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] Heterogeneity in caregiving-related early adversity: Creating stable dimensions and subtypes - CORRIGENDUM [Texte imprimé et/ou numérique] / Aki NIKOLAIDIS, Auteur ; Charlotte HELENIAK, Auteur ; Andrea FIELDS, Auteur ; Paul A. BLOOM, Auteur ; Michelle VANTIEGHEM, Auteur ; Anna VANNUCCI, Auteur ; Nicolas L. CAMACHO, Auteur ; Tricia CHOY, Auteur ; Lisa GIBSON, Auteur ; Chelsea HARMON, Auteur ; Syntia S. HADIS, Auteur ; Ian J. DOUGLAS, Auteur ; Michael P. MILHAM, Auteur ; Nim TOTTENHAM, Auteur . - p.1570-1570. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1570-1570 Mots-clés : caregiving related early adversities  heterogeneity  prediction  subtyping Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579422000529 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

A lack of self-consciousness in Asperger's disorder but not in PDDNOS: Implication for the clinical importance of ASD subtypes / Sayaka YOSHIMURA in Research in Autism Spectrum Disorders, 8-3 (March 2014)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 8-3 (March 2014) . - p.237-243 Titre : A lack of self-consciousness in Asperger's disorder but not in PDDNOS: Implication for the clinical importance of ASD subtypes Type de document : Texte imprimé et/ou numérique Auteurs : Sayaka YOSHIMURA, Auteur ; Motomi TOICHI, Auteur Article en page(s) : p.237-243 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder (ASD)  Subtyping  Self-consciousness  Self-information processing  Memory Index. décimale : PER Périodiques Résumé : Abstract Self-consciousness plays an important role in a person's social life. Assuming that self-consciousness is a key to understanding social impairments in high-functioning autism spectrum disorder (ASD), we examined self-consciousness in individuals with Asperger's disorder, pervasive developmental disorder not otherwise specified (PDDNOS) and their controls using an episodic memory task. The PDDNOS group consisted of individuals in a milder subgroup of PDDNOS, with less autistic features than Asperger's disorder. In the learning phase, one of three types of questions (phonological, semantic, self-referential) was asked about each following target word. The target words were all personality trait adjectives. Next, a recognition test was conducted. The PDDNOS group, like the control, showed the most superior performance in self-referential processing (i.e. the self-reference effect) while the Asperger's group did not; however, both the ASD groups revealed an atypical pattern of relationship between memory performance and IQ. Individuals with PDDNOS, unlike those with Asperger's disorder, may be self-conscious to the same degree as typically developing individuals, but the cognitive process leading them to self-consciousness seems atypical, causing social impairments similar to those seen in individuals with Asperger's disorder who lack self-consciousness. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.12.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=224 [article] A lack of self-consciousness in Asperger's disorder but not in PDDNOS: Implication for the clinical importance of ASD subtypes [Texte imprimé et/ou numérique] / Sayaka YOSHIMURA, Auteur ; Motomi TOICHI, Auteur . - p.237-243. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 8-3 (March 2014) . - p.237-243 Mots-clés : Autism spectrum disorder (ASD)  Subtyping  Self-consciousness  Self-information processing  Memory Index. décimale : PER Périodiques Résumé : Abstract Self-consciousness plays an important role in a person's social life. Assuming that self-consciousness is a key to understanding social impairments in high-functioning autism spectrum disorder (ASD), we examined self-consciousness in individuals with Asperger's disorder, pervasive developmental disorder not otherwise specified (PDDNOS) and their controls using an episodic memory task. The PDDNOS group consisted of individuals in a milder subgroup of PDDNOS, with less autistic features than Asperger's disorder. In the learning phase, one of three types of questions (phonological, semantic, self-referential) was asked about each following target word. The target words were all personality trait adjectives. Next, a recognition test was conducted. The PDDNOS group, like the control, showed the most superior performance in self-referential processing (i.e. the self-reference effect) while the Asperger's group did not; however, both the ASD groups revealed an atypical pattern of relationship between memory performance and IQ. Individuals with PDDNOS, unlike those with Asperger's disorder, may be self-conscious to the same degree as typically developing individuals, but the cognitive process leading them to self-consciousness seems atypical, causing social impairments similar to those seen in individuals with Asperger's disorder who lack self-consciousness. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.12.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=224

Understanding the heterogeneity of anxiety in autistic youth: A person-centered approach / Emily SPACKMAN in Autism Research, 15-9 (September 2022)  

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