Autism Spectrum Disorders and the Family / Lauren PEPA

Public ISBD in Autism Spectrum Disorders in Adolescents and Adults / Matt TINCANI Titre : Autism Spectrum Disorders and the Family Type de document : texte imprimé Auteurs : Lauren PEPA, Auteur ; Sandra L. HARRIS, Auteur Année de publication : 2014 Importance : p.24-43 Langues : Anglais (eng) Index. décimale : ADU-A ADU-A - Adultes - Généralités Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=264 in Autism Spectrum Disorders in Adolescents and Adults / Matt TINCANI Autism Spectrum Disorders and the Family [texte imprimé] / Lauren PEPA, Auteur ; Sandra L. HARRIS, Auteur . - 2014 . - p.24-43. Langues : Anglais (eng) Index. décimale : ADU-A ADU-A - Adultes - Généralités Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=264

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Correction to: The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults / Vanessa H. BAL in Journal of Autism and Developmental Disorders, 51-12 (December 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4504-4505 Titre : Correction to: The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults Type de document : texte imprimé Auteurs : Vanessa H. BAL, Auteur ; Melissa MAYE, Auteur ; Emma SALZMAN, Auteur ; Marisela HUERTA, Auteur ; Lauren PEPA, Auteur ; Susan RISI, Auteur ; Catherine LORD, Auteur Article en page(s) : p.4504-4505 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-021-04888-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 [article] Correction to: The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults [texte imprimé] / Vanessa H. BAL, Auteur ; Melissa MAYE, Auteur ; Emma SALZMAN, Auteur ; Marisela HUERTA, Auteur ; Lauren PEPA, Auteur ; Susan RISI, Auteur ; Catherine LORD, Auteur . - p.4504-4505. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4504-4505 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-021-04888-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454

Diagnostic des troubles du spectre de l’autisme selon le DSM-5 / Cynthia MARTIN

Public ISBD in Evaluer les troubles du spectre de l'autisme / Sam GOLDSTEIN Titre : Diagnostic des troubles du spectre de l’autisme selon le DSM-5 Type de document : texte imprimé Auteurs : Cynthia MARTIN, Auteur ; Lauren PEPA, Auteur ; Catherine LORD, Auteur Année de publication : 2020 Importance : p.53-68 Langues : Français (fre) Index. décimale : AUT-D AUT-D - L'Autisme - Dépistage et Diagnostic Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435 in Evaluer les troubles du spectre de l'autisme / Sam GOLDSTEIN Diagnostic des troubles du spectre de l’autisme selon le DSM-5 [texte imprimé] / Cynthia MARTIN, Auteur ; Lauren PEPA, Auteur ; Catherine LORD, Auteur . - 2020 . - p.53-68. Langues : Français (fre) Index. décimale : AUT-D AUT-D - L'Autisme - Dépistage et Diagnostic Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435

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Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial / Evdokia ANAGNOSTOU in Molecular Autism, (December 2012)  

Public ISBD [article]  inMolecular Autism > (December 2012) . - 9 p. Titre : Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial Type de document : texte imprimé Auteurs : Evdokia ANAGNOSTOU, Auteur ; Latha V. SOORYA, Auteur ; William CHAPLIN, Auteur ; Jennifer BARTZ, Auteur ; Danielle B. HALPERN, Auteur ; Stacey WASSERMAN, Auteur ; A. Ting WANG, Auteur ; Lauren PEPA, Auteur ; Nadia TANEL, Auteur ; Azadeh KUSHKI, Auteur ; Eric HOLLANDER, Auteur Année de publication : 2012 Article en page(s) : 9 p. Langues : Anglais (eng) Mots-clés : Autism  Adults  Oxytocin  Clinical trial  Social cognition Index. décimale : PER Périodiques Résumé : BACKGROUND:There are no effective medications for the treatment of social cognition/function deficits in autism spectrum disorder (ASD), and adult intervention literature in this area is sparse. Emerging data from animal models and genetic association studies as well as early, single-dose intervention studies suggest that the oxytocin system may be a potential therapeutic target for social cognition/function deficits in ASD. The primary aim of this study was to examine the safety/therapeutic effects of intranasal oxytocin versus placebo in adults with ASD, with respect to the two core symptom domains of social cognition/functioning and repetitive behaviors.METHODS:This was a pilot, randomized, double-blind, placebo-controlled, parallel design trial of intranasal oxytocin versus placebo in 19 adults with ASD (16 males; 33.20 +/- 13.29 years). Subjects were randomized to 24 IU intranasal oxytocin or placebo in the morning and afternoon for 6 weeks. Measures of social function/cognition (the Diagnostic Analysis of Nonverbal Accuracy) and repetitive behaviors (Repetitive Behavior Scale Revised) were administered. Secondary measures included the Social Responsiveness Scale, Reading-the-Mind-in-the-Eyes Test and the Yale Brown Obsessive Compulsive Scale - compulsion subscale and quality of life (World Health Organization Quality of Life Questionnaire - emotional/social subscales). Full-information maximum-likelihood parameter estimates were obtained and tested using mixed-effects regression analyses.RESULTS:Although no significant changes were detected in the primary outcome measures after correcting for baseline differences, results suggested improvements after 6 weeks in measures of social cognition (Reading-the-Mind-in-the-Eyes Test, p = 0.002, d = 1.2), and quality of life (World Health Organization Quality of Life Questionnaire - emotion, p = 0.031, d = 0.84), both secondary measures. Oxytocin was well tolerated and no serious adverse effects were reported.CONCLUSIONS:This pilot study suggests that there is therapeutic potential to daily administration of intranasal oxytocin in adults with ASD and that larger and longer studies are warranted.TRIAL REGISTRATION:NCT00490802 En ligne : http://dx.doi.org/10.1186/2040-2392-3-16 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202 [article] Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial [texte imprimé] / Evdokia ANAGNOSTOU, Auteur ; Latha V. SOORYA, Auteur ; William CHAPLIN, Auteur ; Jennifer BARTZ, Auteur ; Danielle B. HALPERN, Auteur ; Stacey WASSERMAN, Auteur ; A. Ting WANG, Auteur ; Lauren PEPA, Auteur ; Nadia TANEL, Auteur ; Azadeh KUSHKI, Auteur ; Eric HOLLANDER, Auteur . - 2012 . - 9 p. Langues : Anglais (eng) in Molecular Autism > (December 2012) . - 9 p. Mots-clés : Autism  Adults  Oxytocin  Clinical trial  Social cognition Index. décimale : PER Périodiques Résumé : BACKGROUND:There are no effective medications for the treatment of social cognition/function deficits in autism spectrum disorder (ASD), and adult intervention literature in this area is sparse. Emerging data from animal models and genetic association studies as well as early, single-dose intervention studies suggest that the oxytocin system may be a potential therapeutic target for social cognition/function deficits in ASD. The primary aim of this study was to examine the safety/therapeutic effects of intranasal oxytocin versus placebo in adults with ASD, with respect to the two core symptom domains of social cognition/functioning and repetitive behaviors.METHODS:This was a pilot, randomized, double-blind, placebo-controlled, parallel design trial of intranasal oxytocin versus placebo in 19 adults with ASD (16 males; 33.20 +/- 13.29 years). Subjects were randomized to 24 IU intranasal oxytocin or placebo in the morning and afternoon for 6 weeks. Measures of social function/cognition (the Diagnostic Analysis of Nonverbal Accuracy) and repetitive behaviors (Repetitive Behavior Scale Revised) were administered. Secondary measures included the Social Responsiveness Scale, Reading-the-Mind-in-the-Eyes Test and the Yale Brown Obsessive Compulsive Scale - compulsion subscale and quality of life (World Health Organization Quality of Life Questionnaire - emotional/social subscales). Full-information maximum-likelihood parameter estimates were obtained and tested using mixed-effects regression analyses.RESULTS:Although no significant changes were detected in the primary outcome measures after correcting for baseline differences, results suggested improvements after 6 weeks in measures of social cognition (Reading-the-Mind-in-the-Eyes Test, p = 0.002, d = 1.2), and quality of life (World Health Organization Quality of Life Questionnaire - emotion, p = 0.031, d = 0.84), both secondary measures. Oxytocin was well tolerated and no serious adverse effects were reported.CONCLUSIONS:This pilot study suggests that there is therapeutic potential to daily administration of intranasal oxytocin in adults with ASD and that larger and longer studies are warranted.TRIAL REGISTRATION:NCT00490802 En ligne : http://dx.doi.org/10.1186/2040-2392-3-16 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202

The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults / Vanessa H. BAL in Journal of Autism and Developmental Disorders, 50-3 (March 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.719-729 Titre : The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults Type de document : texte imprimé Auteurs : Vanessa H. BAL, Auteur ; Melissa MAYE, Auteur ; Emma SALZMAN, Auteur ; Marisela HUERTA, Auteur ; Lauren PEPA, Auteur ; Susan RISI, Auteur ; Catherine LORD, Auteur Article en page(s) : p.719-729 Langues : Anglais (eng) Mots-clés : Ados  Adults  Autism spectrum disorder  Autism symptoms  Minimally verbal Index. décimale : PER Périodiques Résumé : Few measures are appropriate to assess autism symptoms in minimally verbal adolescents and adults. The Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2, Lord et al., in Autism diagnostic observation schedule-2nd edition (ADOS-2). Western Psychological Services, Los Angeles, 2012) Modules 1 and 2 were designed and validated with children whose spoken language ranges from few- to- no words to phrase speech. This study describes the development and initial validation of the Adapted-ADOS (A-ADOS), which includes tasks, materials and behavioral codes modified to be suitable for assessing older minimally verbal individuals. A-ADOS algorithms exhibit comparable sensitivity and improved specificity relative to ADOS-2 Modules 1 and 2. Although further validation is needed, the A-ADOS will facilitate research to further understanding of minimally verbal adults and symptom trajectories across the lifespan. En ligne : http://dx.doi.org/10.1007/s10803-019-04302-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419 [article] The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults [texte imprimé] / Vanessa H. BAL, Auteur ; Melissa MAYE, Auteur ; Emma SALZMAN, Auteur ; Marisela HUERTA, Auteur ; Lauren PEPA, Auteur ; Susan RISI, Auteur ; Catherine LORD, Auteur . - p.719-729. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.719-729 Mots-clés : Ados  Adults  Autism spectrum disorder  Autism symptoms  Minimally verbal Index. décimale : PER Périodiques Résumé : Few measures are appropriate to assess autism symptoms in minimally verbal adolescents and adults. The Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2, Lord et al., in Autism diagnostic observation schedule-2nd edition (ADOS-2). Western Psychological Services, Los Angeles, 2012) Modules 1 and 2 were designed and validated with children whose spoken language ranges from few- to- no words to phrase speech. This study describes the development and initial validation of the Adapted-ADOS (A-ADOS), which includes tasks, materials and behavioral codes modified to be suitable for assessing older minimally verbal individuals. A-ADOS algorithms exhibit comparable sensitivity and improved specificity relative to ADOS-2 Modules 1 and 2. Although further validation is needed, the A-ADOS will facilitate research to further understanding of minimally verbal adults and symptom trajectories across the lifespan. En ligne : http://dx.doi.org/10.1007/s10803-019-04302-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419

The adult outcome of children referred for autism: typology and prediction from childhood / Andrew PICKLES in Journal of Child Psychology and Psychiatry, 61-7 (July 2020)  

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Work, living, and the pursuit of happiness: Vocational and psychosocial outcomes for young adults with autism / Catherine LORD in Autism, 24-7 (October 2020)  

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