Atypical brain lateralisation in the auditory cortex and language performance in 3- to 7-year-old children with high-functioning autism spectrum disorder: a child-customised magnetoencephalography (MEG) study / Yuko YOSHIMURA in Molecular Autism, (October 2013)  

Public ISBD [article]  inMolecular Autism > (October 2013) Titre : Atypical brain lateralisation in the auditory cortex and language performance in 3- to 7-year-old children with high-functioning autism spectrum disorder: a child-customised magnetoencephalography (MEG) study Type de document : texte imprimé Auteurs : Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Kiyomi SHITAMICHI, Auteur ; Sanae UENO, Auteur ; Toshio MUNESUE, Auteur ; Yasuki ONO, Auteur ; Tsunehisa TSUBOKAWA, Auteur ; Yasuhiro HARUTA, Auteur ; Manabu OI, Auteur ; Yo NIIDA, Auteur ; Gerard REMIJN, Auteur ; Tsutomu TAKAHASHI, Auteur ; Michio SUZUKI, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Magnetoencephalography (MEG) is used to measure the auditory evoked magnetic field (AEF), which reflects language-related performance. In young children, however, the simultaneous quantification of the bilateral auditory-evoked response during binaural hearing is difficult using conventional adult-sized MEG systems. Recently, a child-customised MEG device has facilitated the acquisition of bi-hemispheric recordings, even in young children. Using the child-customised MEG device, we previously reported that language-related performance was reflected in the strength of the early component (P50m) of the auditory evoked magnetic field (AEF) in typically developing (TD) young children (2 to 5 years old) [Eur J Neurosci 2012, 35:644-650]. The aim of this study was to investigate how this neurophysiological index in each hemisphere is correlated with language performance in autism spectrum disorder (ASD) and TD children. We used magnetoencephalography (MEG) to measure the auditory evoked magnetic field (AEF), which reflects language-related performance. We investigated the P50m that is evoked by voice stimuli (/ne/) bilaterally in 33 young children (3 to 7 years old) with ASD and in 30 young children who were typically developing (TD). The children were matched according to their age (in months) and gender. Most of the children with ASD were high-functioning subjects. The results showed that the children with ASD exhibited significantly less leftward lateralisation in their P50m intensity compared with the TD children. Furthermore, the results of a multiple regression analysis indicated that a shorter P50m latency in both hemispheres was specifically correlated with higher language-related performance in the TD children, whereas this latency was not correlated with non-verbal cognitive performance or chronological age. The children with ASD did not show any correlation between P50m latency and language-related performance; instead, increasing chronological age was a significant predictor of shorter P50m latency in the right hemisphere. Using a child-customised MEG device, we studied the P50m component that was evoked through binaural human voice stimuli in young ASD and TD children to examine differences in auditory cortex function that are associated with language development. Our results suggest that there is atypical brain function in the auditory cortex in young children with ASD, regardless of language development. En ligne : http://dx.doi.org/10.1186/2040-2392-4-38 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=227 [article] Atypical brain lateralisation in the auditory cortex and language performance in 3- to 7-year-old children with high-functioning autism spectrum disorder: a child-customised magnetoencephalography (MEG) study [texte imprimé] / Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Kiyomi SHITAMICHI, Auteur ; Sanae UENO, Auteur ; Toshio MUNESUE, Auteur ; Yasuki ONO, Auteur ; Tsunehisa TSUBOKAWA, Auteur ; Yasuhiro HARUTA, Auteur ; Manabu OI, Auteur ; Yo NIIDA, Auteur ; Gerard REMIJN, Auteur ; Tsutomu TAKAHASHI, Auteur ; Michio SUZUKI, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur. Langues : Anglais (eng) in Molecular Autism > (October 2013) Index. décimale : PER Périodiques Résumé : Magnetoencephalography (MEG) is used to measure the auditory evoked magnetic field (AEF), which reflects language-related performance. In young children, however, the simultaneous quantification of the bilateral auditory-evoked response during binaural hearing is difficult using conventional adult-sized MEG systems. Recently, a child-customised MEG device has facilitated the acquisition of bi-hemispheric recordings, even in young children. Using the child-customised MEG device, we previously reported that language-related performance was reflected in the strength of the early component (P50m) of the auditory evoked magnetic field (AEF) in typically developing (TD) young children (2 to 5 years old) [Eur J Neurosci 2012, 35:644-650]. The aim of this study was to investigate how this neurophysiological index in each hemisphere is correlated with language performance in autism spectrum disorder (ASD) and TD children. We used magnetoencephalography (MEG) to measure the auditory evoked magnetic field (AEF), which reflects language-related performance. We investigated the P50m that is evoked by voice stimuli (/ne/) bilaterally in 33 young children (3 to 7 years old) with ASD and in 30 young children who were typically developing (TD). The children were matched according to their age (in months) and gender. Most of the children with ASD were high-functioning subjects. The results showed that the children with ASD exhibited significantly less leftward lateralisation in their P50m intensity compared with the TD children. Furthermore, the results of a multiple regression analysis indicated that a shorter P50m latency in both hemispheres was specifically correlated with higher language-related performance in the TD children, whereas this latency was not correlated with non-verbal cognitive performance or chronological age. The children with ASD did not show any correlation between P50m latency and language-related performance; instead, increasing chronological age was a significant predictor of shorter P50m latency in the right hemisphere. Using a child-customised MEG device, we studied the P50m component that was evoked through binaural human voice stimuli in young ASD and TD children to examine differences in auditory cortex function that are associated with language development. Our results suggest that there is atypical brain function in the auditory cortex in young children with ASD, regardless of language development. En ligne : http://dx.doi.org/10.1186/2040-2392-4-38 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=227

Atypical development of the central auditory system in young children with Autism spectrum disorder / Yuko YOSHIMURA in Autism Research, 9-11 (November 2016)  

Public ISBD [article]  inAutism Research > 9-11 (November 2016) . - p.1216-1226 Titre : Atypical development of the central auditory system in young children with Autism spectrum disorder Type de document : texte imprimé Auteurs : Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Hirotoshi HIRAISHI, Auteur ; Chiaki HASEGAWA, Auteur ; Tetsuya TAKAHASHI, Auteur ; Gerard REMIJN, Auteur ; Manabu OI, Auteur ; Toshio MUNESUE, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur ; Haruyuki KOJIMA, Auteur Article en page(s) : p.1216-1226 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  magnetoencephalography  P1m  young children Index. décimale : PER Périodiques Résumé : The P1m component of the auditory evoked magnetic field is the earliest cortical response associated with language acquisition. However, the growth curve of the P1m component is unknown in both typically developing (TD) and atypically developing children. The aim of this study is to clarify the developmental pattern of this component when evoked by binaural human voice stimulation using child-customized magnetoencephalography. A total of 35 young TD children (32–121 months of age) and 35 children with autism spectrum disorder (ASD) (38–111 months of age) participated in this study. This is the first report to demonstrate an inverted U-shaped growth curve for the P1m dipole intensity in the left hemisphere in TD children. In addition, our results revealed a more diversified age-related distribution of auditory brain responses in 3- to 9-year-old children with ASD. These results demonstrate the diversified growth curve of the P1m component in ASD during young childhood, which is a crucial period for first language acquisition. En ligne : http://dx.doi.org/10.1002/aur.1604 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297 [article] Atypical development of the central auditory system in young children with Autism spectrum disorder [texte imprimé] / Yuko YOSHIMURA, Auteur ; Mitsuru KIKUCHI, Auteur ; Hirotoshi HIRAISHI, Auteur ; Chiaki HASEGAWA, Auteur ; Tetsuya TAKAHASHI, Auteur ; Gerard REMIJN, Auteur ; Manabu OI, Auteur ; Toshio MUNESUE, Auteur ; Haruhiro HIGASHIDA, Auteur ; Yoshio MINABE, Auteur ; Haruyuki KOJIMA, Auteur . - p.1216-1226. Langues : Anglais (eng) in Autism Research > 9-11 (November 2016) . - p.1216-1226 Mots-clés : autism spectrum disorder  magnetoencephalography  P1m  young children Index. décimale : PER Périodiques Résumé : The P1m component of the auditory evoked magnetic field is the earliest cortical response associated with language acquisition. However, the growth curve of the P1m component is unknown in both typically developing (TD) and atypically developing children. The aim of this study is to clarify the developmental pattern of this component when evoked by binaural human voice stimulation using child-customized magnetoencephalography. A total of 35 young TD children (32–121 months of age) and 35 children with autism spectrum disorder (ASD) (38–111 months of age) participated in this study. This is the first report to demonstrate an inverted U-shaped growth curve for the P1m dipole intensity in the left hemisphere in TD children. In addition, our results revealed a more diversified age-related distribution of auditory brain responses in 3- to 9-year-old children with ASD. These results demonstrate the diversified growth curve of the P1m component in ASD during young childhood, which is a crucial period for first language acquisition. En ligne : http://dx.doi.org/10.1002/aur.1604 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297

Brief Report: Evaluating the Utility of Varied Technological Agents to Elicit Social Attention from Children with Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 49-4 (April 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1700-1708 Titre : Brief Report: Evaluating the Utility of Varied Technological Agents to Elicit Social Attention from Children with Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Zachary WARREN, Auteur ; Amy SWANSON, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Yuki MATSUMOTO, Auteur ; Yuko YOSHIMURA, Auteur ; Jiro SHIMAYA, Auteur ; Hiroshi ISHIGURO, Auteur ; Nilanjan SARKAR, Auteur ; Joshua WADE, Auteur ; Masaru MIMURA, Auteur ; Yoshio MINABE, Auteur ; Mitsuru KIKUCHI, Auteur Article en page(s) : p.1700-1708 Langues : Anglais (eng) Mots-clés : Android robot  Autism spectrum disorders  Digital avatar  Robot  Technological agents Index. décimale : PER Périodiques Résumé : Technological agents could be effective tools to be used in interventions for enhancing social orienting for some young children with ASD. We examined response to social bids in preschool children with ASD and typical development (TD) at a very early age (i.e., around 3 years) using social prompts presented by technological agents of various forms and human comparisons. Children with ASD demonstrated less response overall to social bids compared to TD controls, across agents or human. They responded more often to a simple humanoid robot and the simple avatar compared to the human. These results support the potential utilization of specific robotic and technological agents for harnessing and potentially increasing motivation to socially-relevant behaviors in some young children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3841-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 [article] Brief Report: Evaluating the Utility of Varied Technological Agents to Elicit Social Attention from Children with Autism Spectrum Disorders [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Zachary WARREN, Auteur ; Amy SWANSON, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Yuki MATSUMOTO, Auteur ; Yuko YOSHIMURA, Auteur ; Jiro SHIMAYA, Auteur ; Hiroshi ISHIGURO, Auteur ; Nilanjan SARKAR, Auteur ; Joshua WADE, Auteur ; Masaru MIMURA, Auteur ; Yoshio MINABE, Auteur ; Mitsuru KIKUCHI, Auteur . - p.1700-1708. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1700-1708 Mots-clés : Android robot  Autism spectrum disorders  Digital avatar  Robot  Technological agents Index. décimale : PER Périodiques Résumé : Technological agents could be effective tools to be used in interventions for enhancing social orienting for some young children with ASD. We examined response to social bids in preschool children with ASD and typical development (TD) at a very early age (i.e., around 3 years) using social prompts presented by technological agents of various forms and human comparisons. Children with ASD demonstrated less response overall to social bids compared to TD controls, across agents or human. They responded more often to a simple humanoid robot and the simple avatar compared to the human. These results support the potential utilization of specific robotic and technological agents for harnessing and potentially increasing motivation to socially-relevant behaviors in some young children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3841-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388

Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 49-4 (April 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1709-1716 Titre : Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Jiro SHIMAYA, Auteur ; Hiroshi ISHIGURO, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur Article en page(s) : p.1709-1716 Langues : Anglais (eng) Mots-clés : Ados  Autism spectrum disorders  Robot  Severity  Social communication  Typical development Index. décimale : PER Périodiques Résumé : We investigated the feasibility of our novel evaluation system for use with children with autism spectrum disorders (ASD). We prepared the experimental setting with two humanoid robots in reference to the birthday party scene in the Autism Diagnostic Observational Schedule (ADOS). We assessed the relationship between social communication ability measured in the ADOS condition (i.e., with a human clinician) and in a robotic condition for children with ASD. There were significant correlations between the social communication scores in the gold-standard ADOS condition and the robotic condition for children with ASD. The current work provides support for a unique application of a robotic system (i.e., two robot-mediated interaction) to evaluate the severity of autistic traits for children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3848-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 [article] Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Jiro SHIMAYA, Auteur ; Hiroshi ISHIGURO, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur . - p.1709-1716. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1709-1716 Mots-clés : Ados  Autism spectrum disorders  Robot  Severity  Social communication  Typical development Index. décimale : PER Périodiques Résumé : We investigated the feasibility of our novel evaluation system for use with children with autism spectrum disorders (ASD). We prepared the experimental setting with two humanoid robots in reference to the birthday party scene in the Autism Diagnostic Observational Schedule (ADOS). We assessed the relationship between social communication ability measured in the ADOS condition (i.e., with a human clinician) and in a robotic condition for children with ASD. There were significant correlations between the social communication scores in the gold-standard ADOS condition and the robotic condition for children with ASD. The current work provides support for a unique application of a robotic system (i.e., two robot-mediated interaction) to evaluate the severity of autistic traits for children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3848-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388

Brief Report: Odour Awareness in Young Children with Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 50-5 (May 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-5 (May 2020) . - p.1809-1815 Titre : Brief Report: Odour Awareness in Young Children with Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Masako OKAMOTO, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Ryoichiro IWANAGA, Auteur ; Sara TOMIYAMA, Auteur ; Kyung-Min AN, Auteur ; Yoshio MINABE, Auteur ; Mitsuru KIKUCHI, Auteur Article en page(s) : p.1809-1815 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Odour awareness  Olfactory  Self-report  Vabs ii Index. décimale : PER Périodiques Résumé : The elucidation of odour awareness in children with autism spectrum disorders (ASD) is important. We compared the odour awareness of young children with ASD with those of typical development (TD) children using the Children's Olfactory Behavior in Everyday Life (COBEL) questionnaire, which is a self-report measure that mainly assesses odour awareness. Forty-five young boys (aged 5-6 years), including 20 children with ASD and 25 TD children, participated in this study. The total COBEL score of the young children with ASD was lower than that of the TD children (p < 0.01). Moreover, the total COBEL score was significantly correlated with the total VABS II score (p < 0.05). Our results improve understanding of the odour awareness in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3710-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422 [article] Brief Report: Odour Awareness in Young Children with Autism Spectrum Disorders [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Masako OKAMOTO, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Ryoichiro IWANAGA, Auteur ; Sara TOMIYAMA, Auteur ; Kyung-Min AN, Auteur ; Yoshio MINABE, Auteur ; Mitsuru KIKUCHI, Auteur . - p.1809-1815. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-5 (May 2020) . - p.1809-1815 Mots-clés : Autism spectrum disorders  Odour awareness  Olfactory  Self-report  Vabs ii Index. décimale : PER Périodiques Résumé : The elucidation of odour awareness in children with autism spectrum disorders (ASD) is important. We compared the odour awareness of young children with ASD with those of typical development (TD) children using the Children's Olfactory Behavior in Everyday Life (COBEL) questionnaire, which is a self-report measure that mainly assesses odour awareness. Forty-five young boys (aged 5-6 years), including 20 children with ASD and 25 TD children, participated in this study. The total COBEL score of the young children with ASD was lower than that of the TD children (p < 0.01). Moreover, the total COBEL score was significantly correlated with the total VABS II score (p < 0.05). Our results improve understanding of the odour awareness in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3710-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422

Brief Report: Olfactory Adaptation in Children with Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 49-8 (August 2019)  

Permalink

Developmental changes in attention to social information from childhood to adolescence in autism spectrum disorders: a comparative study / Toru FUJIOKA in Molecular Autism, 11 (2020)  

Permalink

Impressions of Humanness for Android Robot may Represent an Endophenotype for Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 48-2 (February 2018)  

Permalink

Job interview training targeting nonverbal communication using an android robot for individuals with autism spectrum disorder / Hirokazu KUMAZAKI in Autism, 23-6 (August 2019)  

Permalink

Joint attention and intelligence in children with autism spectrum disorder without severe intellectual disability / Misako SANO in Autism Research, 14-12 (December 2021)  

Permalink

A pilot study of serotonergic modulation after long-term administration of oxytocin in autism spectrum disorder / Tetsu HIROSAWA in Autism Research, 10-5 (May 2017)  

Permalink

Quantitative Aspects of Communicative Impairment Ascertained in a Large National Survey of Japanese Children / Manabu OI in Journal of Autism and Developmental Disorders, 47-10 (October 2017)  

Permalink

Relationship Between Odor Identification and Visual Distractors in Children with Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 48-7 (July 2018)  

Permalink

The impact of robotic intervention on joint attention in children with autism spectrum disorders / Hirokazu KUMAZAKI in Molecular Autism, 9 (2018)  

Permalink

---

1 (1 - 14 / 14) Par page : 25 50 100 200