Dépouillements

Editorial: Envisioning the Future after 50 Years of Science and Discovery / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.1 Titre : Editorial: Envisioning the Future after 50 Years of Science and Discovery Type de document : Texte imprimé et/ou numérique Auteurs : Tony CHARMAN, Auteur ; James F. LECKMAN, Auteur ; Frank C. VERHULST, Auteur Année de publication : 2009 Article en page(s) : p.1 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02063.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693 [article] Editorial: Envisioning the Future after 50 Years of Science and Discovery [Texte imprimé et/ou numérique] / Tony CHARMAN, Auteur ; James F. LECKMAN, Auteur ; Frank C. VERHULST, Auteur . - 2009 . - p.1. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.1 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02063.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693

JCPP – The Journal of Child Psychology and Psychiatry: a history from the inside / Michael BERGER in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.2-8 Titre : JCPP – The Journal of Child Psychology and Psychiatry: a history from the inside Type de document : Texte imprimé et/ou numérique Auteurs : Michael BERGER, Auteur ; Lionel HERSOV, Auteur Année de publication : 2009 Article en page(s) : p.2-8 Langues : Anglais (eng) Mots-clés : History JCPP anniversary clinical-relevance impact-factor open-access JCPP-Editors Index. décimale : PER Périodiques Résumé : As the JCPP marks its 50th year of publication, this paper revisits the founding philosophy and traces the journey from the first issue through to the present. The history of the JCPP reflects the many changes that have come about in the fields of developmental psychology and child and adolescent psychiatry and the changes introduced both to meet the needs and shape the practices of clinicians and researchers. It documents the achievements of the Journal and the contributions made by many in enabling its success. As the JCPP moves forward it will enjoy the benefits of the major technological and other advances being made in research, in the evolving and expanding knowledge base, and in the modes of publication, as well as needing to manage the associated challenges that will inevitably impact on its future. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02036.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693 [article] JCPP – The Journal of Child Psychology and Psychiatry: a history from the inside [Texte imprimé et/ou numérique] / Michael BERGER, Auteur ; Lionel HERSOV, Auteur . - 2009 . - p.2-8. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.2-8 Mots-clés : History JCPP anniversary clinical-relevance impact-factor open-access JCPP-Editors Index. décimale : PER Périodiques Résumé : As the JCPP marks its 50th year of publication, this paper revisits the founding philosophy and traces the journey from the first issue through to the present. The history of the JCPP reflects the many changes that have come about in the fields of developmental psychology and child and adolescent psychiatry and the changes introduced both to meet the needs and shape the practices of clinicians and researchers. It documents the achievements of the Journal and the contributions made by many in enabling its success. As the JCPP moves forward it will enjoy the benefits of the major technological and other advances being made in research, in the evolving and expanding knowledge base, and in the modes of publication, as well as needing to manage the associated challenges that will inevitably impact on its future. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02036.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693

Nosology and measurement in child and adolescent psychiatry / Adrian ANGOLD in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.9-15 Titre : Nosology and measurement in child and adolescent psychiatry Type de document : Texte imprimé et/ou numérique Auteurs : Adrian ANGOLD, Auteur ; E. Jane COSTELLO, Auteur Année de publication : 2009 Article en page(s) : p.9-15 Langues : Anglais (eng) Mots-clés : Child adolescent nosology assessment measurement Index. décimale : PER Périodiques Résumé : The last 50 years have witnessed enormous strides in the measurement and classification of child and adolescent psychiatric disorders. Debates about whether we should continue to depend upon a categorical nosology still continue, but we argue that, despite the absence of clear dividing lines between psychiatric disorders and normality and ubiquity of diagnostic comorbidity, the current official approach to nosology has served child and adolescent psychiatric research surprisingly well. In particular we point to the utility of non-developmental diagnostic criteria as tools for discovering developmental effects on psychopathology. We also maintain that the search for sharper boundaries between disorders is fundamentally mistaken. However, official nosologies have tended to privilege information collected in diagnostic interviews and to sideline observational and other methods that cannot easily be made to conform to the format of their criteria. We suggest that it is time to remedy this situation. The ICD-10 and DSM-IV are useless for children under the age of about two, while alternatives, such as the DC:0–3, suffer from a profound lack of empirical support. We suggest a way forward through the integration of methods from temperament and psychopathology research. Finally, we deplore the failure of standardized assessment techniques to have penetrated more deeply into everyday clinical assessment. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01981.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693 [article] Nosology and measurement in child and adolescent psychiatry [Texte imprimé et/ou numérique] / Adrian ANGOLD, Auteur ; E. Jane COSTELLO, Auteur . - 2009 . - p.9-15. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.9-15 Mots-clés : Child adolescent nosology assessment measurement Index. décimale : PER Périodiques Résumé : The last 50 years have witnessed enormous strides in the measurement and classification of child and adolescent psychiatric disorders. Debates about whether we should continue to depend upon a categorical nosology still continue, but we argue that, despite the absence of clear dividing lines between psychiatric disorders and normality and ubiquity of diagnostic comorbidity, the current official approach to nosology has served child and adolescent psychiatric research surprisingly well. In particular we point to the utility of non-developmental diagnostic criteria as tools for discovering developmental effects on psychopathology. We also maintain that the search for sharper boundaries between disorders is fundamentally mistaken. However, official nosologies have tended to privilege information collected in diagnostic interviews and to sideline observational and other methods that cannot easily be made to conform to the format of their criteria. We suggest that it is time to remedy this situation. The ICD-10 and DSM-IV are useless for children under the age of about two, while alternatives, such as the DC:0–3, suffer from a profound lack of empirical support. We suggest a way forward through the integration of methods from temperament and psychopathology research. Finally, we deplore the failure of standardized assessment techniques to have penetrated more deeply into everyday clinical assessment. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01981.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693

The past achievements and future promises of developmental psychopathology: the coming of age of a discipline / Dante CICCHETTI in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.16-25 Titre : The past achievements and future promises of developmental psychopathology: the coming of age of a discipline Type de document : Texte imprimé et/ou numérique Auteurs : Dante CICCHETTI, Auteur ; Sheree L. TOTH, Auteur Année de publication : 2009 Article en page(s) : p.16-25 Langues : Anglais (eng) Mots-clés : Developmental-psychopathology interdisciplinary multiple-levels-of-analysis translational-research Index. décimale : PER Périodiques Résumé : Over the past decades, developmental psychopathology has coalesced into a discipline that has made significant contributions toward the understanding of risk, psychopathology, and resilience in individuals across the life course. The overarching goal of the discipline has been to elucidate the interplay among biological, psychological, and social-contextual aspects of normal and abnormal development. In addition to directing efforts toward bridging fields of study and aiding in elucidating important truths about the processes underlying adaptation and maladaptation, investigators in developmental psychopathology have been equally devoted to developing and evaluating methods for preventing and ameliorating maladaptive and psychopathological outcomes. Increasingly, efforts are being made to conduct investigations at multiple levels of analysis and to translate basic research knowledge into real-world contexts. In this article, the contributions, challenges, and future directions of the field are highlighted. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01979.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693 [article] The past achievements and future promises of developmental psychopathology: the coming of age of a discipline [Texte imprimé et/ou numérique] / Dante CICCHETTI, Auteur ; Sheree L. TOTH, Auteur . - 2009 . - p.16-25. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.16-25 Mots-clés : Developmental-psychopathology interdisciplinary multiple-levels-of-analysis translational-research Index. décimale : PER Périodiques Résumé : Over the past decades, developmental psychopathology has coalesced into a discipline that has made significant contributions toward the understanding of risk, psychopathology, and resilience in individuals across the life course. The overarching goal of the discipline has been to elucidate the interplay among biological, psychological, and social-contextual aspects of normal and abnormal development. In addition to directing efforts toward bridging fields of study and aiding in elucidating important truths about the processes underlying adaptation and maladaptation, investigators in developmental psychopathology have been equally devoted to developing and evaluating methods for preventing and ameliorating maladaptive and psychopathological outcomes. Increasingly, efforts are being made to conduct investigations at multiple levels of analysis and to translate basic research knowledge into real-world contexts. In this article, the contributions, challenges, and future directions of the field are highlighted. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01979.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693

Prerequisites for global child and adolescent mental health / Leon EISENBERG in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.26-35 Titre : Prerequisites for global child and adolescent mental health Type de document : Texte imprimé et/ou numérique Auteurs : Leon EISENBERG, Auteur ; Myron L. BELFER, Auteur Année de publication : 2009 Article en page(s) : p.26-35 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The epidemiology of the mental and physical health of children and adolescents the world over reflects: the genomes they inherit (and the modifications those genes undergo in utero); the pregnancies that led to their births, whether their mothers survive those pregnancies, and whether their births were welcome; the parents, the neighbors, and the neighborhoods they 'inherit' along with their genomes; when and where they live (by cohort, by country, and by province); the air they breathe; the water they drink; what and how much they eat; the schools they attend (and by whom they are taught what and for how long); the energy they expend; the family status in the social order; the friends they have; and last but not least, the amount and kind of medical and psychiatric care they receive. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01984.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693 [article] Prerequisites for global child and adolescent mental health [Texte imprimé et/ou numérique] / Leon EISENBERG, Auteur ; Myron L. BELFER, Auteur . - 2009 . - p.26-35. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.26-35 Index. décimale : PER Périodiques Résumé : The epidemiology of the mental and physical health of children and adolescents the world over reflects: the genomes they inherit (and the modifications those genes undergo in utero); the pregnancies that led to their births, whether their mothers survive those pregnancies, and whether their births were welcome; the parents, the neighbors, and the neighborhoods they 'inherit' along with their genomes; when and where they live (by cohort, by country, and by province); the air they breathe; the water they drink; what and how much they eat; the schools they attend (and by whom they are taught what and for how long); the energy they expend; the family status in the social order; the friends they have; and last but not least, the amount and kind of medical and psychiatric care they receive. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01984.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693

Personal reflections on observational and experimental research approaches to childhood psychopathology / Judith RAPOPORT in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.36-43 Titre : Personal reflections on observational and experimental research approaches to childhood psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Judith RAPOPORT, Auteur Année de publication : 2009 Article en page(s) : p.36-43 Langues : Anglais (eng) Mots-clés : Attention-deficit-hyperactivity-disorder child-psychiatry childhood-onset-schizophrenia epidemiology experimental-research follow-up-studies observational-research obsessive-compulsive-disorder pervasive-developmental-disorder stimulants Index. décimale : PER Périodiques Résumé : The past 50 years have seen dramatic changes in childhood psychopathology research. The goal of this overview is to contrast observational and experimental research approaches; both have grown more complex such that the boundary between these approaches may be blurred. Both are essential. Landmark observational studies with long-term follow-up (Robins, 1966; Yarrow, Campbell, & Burton, 1970) have had – and continue to have – unique impact on clinical research and practice. Epidemiological studies showed high rates of psychological disorder and their close tie to neurological impairment (Rutter, Tizard, & Whitemore, 1970). These studies have current impact with respect to brain imaging correlates of clinical outcome. Pharmacological studies, particularly those on stimulants and on treatment of pediatric obsessive compulsive disorder (OCD), have propelled experimental methodology and inspired translational approaches. Predicted future trends are: more informed subgrouping of our heterogeneous phenotypes, reliance on multicenter trials, and documentation of non-conventional methods of care delivery. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01975.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693 [article] Personal reflections on observational and experimental research approaches to childhood psychopathology [Texte imprimé et/ou numérique] / Judith RAPOPORT, Auteur . - 2009 . - p.36-43. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.36-43 Mots-clés : Attention-deficit-hyperactivity-disorder child-psychiatry childhood-onset-schizophrenia epidemiology experimental-research follow-up-studies observational-research obsessive-compulsive-disorder pervasive-developmental-disorder stimulants Index. décimale : PER Périodiques Résumé : The past 50 years have seen dramatic changes in childhood psychopathology research. The goal of this overview is to contrast observational and experimental research approaches; both have grown more complex such that the boundary between these approaches may be blurred. Both are essential. Landmark observational studies with long-term follow-up (Robins, 1966; Yarrow, Campbell, & Burton, 1970) have had – and continue to have – unique impact on clinical research and practice. Epidemiological studies showed high rates of psychological disorder and their close tie to neurological impairment (Rutter, Tizard, & Whitemore, 1970). These studies have current impact with respect to brain imaging correlates of clinical outcome. Pharmacological studies, particularly those on stimulants and on treatment of pediatric obsessive compulsive disorder (OCD), have propelled experimental methodology and inspired translational approaches. Predicted future trends are: more informed subgrouping of our heterogeneous phenotypes, reliance on multicenter trials, and documentation of non-conventional methods of care delivery. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01975.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693

Understanding and testing risk mechanisms for mental disorders / Michael RUTTER in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.44-52 Titre : Understanding and testing risk mechanisms for mental disorders Type de document : Texte imprimé et/ou numérique Auteurs : Michael RUTTER, Auteur Année de publication : 2009 Article en page(s) : p.44-52 Langues : Anglais (eng) Mots-clés : Mediation moderation genetic-vs.-environmental-mediation natural-experiments causal-inferences Index. décimale : PER Périodiques Résumé : Over the past 50 years there has been a virtual revolution in thinking about risk mechanisms. The key areas of challenge and opportunity include: identification of environmental causes; use of natural experiments; gene–environment interaction; testing for mediation; developmental moderation; biological programming; and developmental perturbations. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01976.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693 [article] Understanding and testing risk mechanisms for mental disorders [Texte imprimé et/ou numérique] / Michael RUTTER, Auteur . - 2009 . - p.44-52. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.44-52 Mots-clés : Mediation moderation genetic-vs.-environmental-mediation natural-experiments causal-inferences Index. décimale : PER Périodiques Résumé : Over the past 50 years there has been a virtual revolution in thinking about risk mechanisms. The key areas of challenge and opportunity include: identification of environmental causes; use of natural experiments; gene–environment interaction; testing for mediation; developmental moderation; biological programming; and developmental perturbations. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01976.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=693

Using epidemiologic methods to test hypotheses regarding causal influences on child and adolescent mental disorders / Benjamin B. LAHEY in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.53-62 Titre : Using epidemiologic methods to test hypotheses regarding causal influences on child and adolescent mental disorders Type de document : Texte imprimé et/ou numérique Auteurs : Benjamin B. LAHEY, Auteur ; Brian M. D'ONOFRIO, Auteur ; Irwin D. WALDMAN, Auteur Année de publication : 2009 Article en page(s) : p.53-62 Langues : Anglais (eng) Mots-clés : Epidemiology developmental-psychopathology taxonomy causal-models Index. décimale : PER Périodiques Résumé : Epidemiology uses strong sampling methods and study designs to test refutable hypotheses regarding the causes of important health, mental health, and social outcomes. Epidemiologic methods are increasingly being used to move developmental psychopathology from studies that catalogue correlates of child and adolescent mental health to designs that can test rival hypotheses regarding causal genetic and environmental influences. A two-part strategy is proposed for the next phase of epidemiologic research. First, to facilitate the most informed tests of causal hypotheses, it is necessary to develop and test models of the structure of hypothesized genetic and environmental influences on mental health phenotypes. This will involve testing the related hypotheses that there are both (a) dimensions of psychopathology that are distinct in the sense of having at least some unique genetic and/or environmental influences, and (b) higher-order domains of correlated dimensions that are all apparently influenced in part by the same genetic and/or environmental factors. The resulting causal taxonomy would organize tests of causal hypotheses regarding both factors that may broadly increase risk for multiple dimensions of psychopathology and factors that may specifically increase risk for each individual dimension. Second, it is necessary to make greater use of a number of powerful epidemiologic designs that allow rigorous tests of rival hypotheses regarding genetic and environmental causes. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01980.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Using epidemiologic methods to test hypotheses regarding causal influences on child and adolescent mental disorders [Texte imprimé et/ou numérique] / Benjamin B. LAHEY, Auteur ; Brian M. D'ONOFRIO, Auteur ; Irwin D. WALDMAN, Auteur . - 2009 . - p.53-62. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.53-62 Mots-clés : Epidemiology developmental-psychopathology taxonomy causal-models Index. décimale : PER Périodiques Résumé : Epidemiology uses strong sampling methods and study designs to test refutable hypotheses regarding the causes of important health, mental health, and social outcomes. Epidemiologic methods are increasingly being used to move developmental psychopathology from studies that catalogue correlates of child and adolescent mental health to designs that can test rival hypotheses regarding causal genetic and environmental influences. A two-part strategy is proposed for the next phase of epidemiologic research. First, to facilitate the most informed tests of causal hypotheses, it is necessary to develop and test models of the structure of hypothesized genetic and environmental influences on mental health phenotypes. This will involve testing the related hypotheses that there are both (a) dimensions of psychopathology that are distinct in the sense of having at least some unique genetic and/or environmental influences, and (b) higher-order domains of correlated dimensions that are all apparently influenced in part by the same genetic and/or environmental factors. The resulting causal taxonomy would organize tests of causal hypotheses regarding both factors that may broadly increase risk for multiple dimensions of psychopathology and factors that may specifically increase risk for each individual dimension. Second, it is necessary to make greater use of a number of powerful epidemiologic designs that allow rigorous tests of rival hypotheses regarding genetic and environmental causes. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01980.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA / Robert PLOMIN in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.63-71 Titre : The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA Type de document : Texte imprimé et/ou numérique Auteurs : Robert PLOMIN, Auteur ; Oliver S.P. DAVIS, Auteur Année de publication : 2009 Article en page(s) : p.63-71 Langues : Anglais (eng) Mots-clés : Microarray genome-wide-association quantitative-trait-loci non-coding-RNA behavioural-genomics Index. décimale : PER Périodiques Résumé : Background: Much of what we thought we knew about genetics needs to be modified in light of recent discoveries. What are the implications of these advances for identifying genes responsible for the high heritability of many behavioural disorders and dimensions in childhood? Methods: Although quantitative genetics such as twin studies will continue to yield important findings, nothing will advance the field as much as identifying the specific genes responsible for heritability. Advances in molecular genetics have been driven by technology, especially DNA microarrays the size of a postage stamp that can genotype a million DNA markers simultaneously. DNA microarrays have led to a dramatic shift in research towards genome-wide association (GWA) studies. The ultimate goal of GWA is to sequence each individual's entire genome, which has begun to happen. Results: GWA studies suggest that for most complex traits and common disorders genetic effects are much smaller than previously considered: The largest effects account for only 1% of the variance of quantitative traits. This finding implies that hundreds of genes are responsible for the heritability of behavioural problems in childhood, and that it will be difficult to identify reliably these genes of small effect. Another discovery with far-reaching implications for future genetic research is the importance of non-coding RNA (DNA transcribed into RNA but not translated into amino acid sequences), which redefines what the word gene means. Non-coding RNA underlines the need for a genome-wide approach that is not limited to the 2% of DNA responsible for specifying the amino acid sequences of proteins. Conclusions: The only safe prediction is that the fast pace of genetic discoveries will continue and will increasingly affect research in child psychology and psychiatry. DNA microarrays will make it possible to use hundreds of genes to predict genetic risk and to use these sets of genes in top-down behavioural genomic research that explores developmental change and continuity, multivariate heterogeneity and co-morbidity, and gene–environment interaction and correlation. A crucial question is whether the prediction of genetic risk will be sufficiently robust to translate into genetically based diagnoses, personalised treatments, and prevention programmes. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01978.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] The future of genetics in psychology and psychiatry: microarrays, genome-wide association, and non-coding RNA [Texte imprimé et/ou numérique] / Robert PLOMIN, Auteur ; Oliver S.P. DAVIS, Auteur . - 2009 . - p.63-71. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.63-71 Mots-clés : Microarray genome-wide-association quantitative-trait-loci non-coding-RNA behavioural-genomics Index. décimale : PER Périodiques Résumé : Background: Much of what we thought we knew about genetics needs to be modified in light of recent discoveries. What are the implications of these advances for identifying genes responsible for the high heritability of many behavioural disorders and dimensions in childhood? Methods: Although quantitative genetics such as twin studies will continue to yield important findings, nothing will advance the field as much as identifying the specific genes responsible for heritability. Advances in molecular genetics have been driven by technology, especially DNA microarrays the size of a postage stamp that can genotype a million DNA markers simultaneously. DNA microarrays have led to a dramatic shift in research towards genome-wide association (GWA) studies. The ultimate goal of GWA is to sequence each individual's entire genome, which has begun to happen. Results: GWA studies suggest that for most complex traits and common disorders genetic effects are much smaller than previously considered: The largest effects account for only 1% of the variance of quantitative traits. This finding implies that hundreds of genes are responsible for the heritability of behavioural problems in childhood, and that it will be difficult to identify reliably these genes of small effect. Another discovery with far-reaching implications for future genetic research is the importance of non-coding RNA (DNA transcribed into RNA but not translated into amino acid sequences), which redefines what the word gene means. Non-coding RNA underlines the need for a genome-wide approach that is not limited to the 2% of DNA responsible for specifying the amino acid sequences of proteins. Conclusions: The only safe prediction is that the fast pace of genetic discoveries will continue and will increasingly affect research in child psychology and psychiatry. DNA microarrays will make it possible to use hundreds of genes to predict genetic risk and to use these sets of genes in top-down behavioural genomic research that explores developmental change and continuity, multivariate heterogeneity and co-morbidity, and gene–environment interaction and correlation. A crucial question is whether the prediction of genetic risk will be sufficiently robust to translate into genetically based diagnoses, personalised treatments, and prevention programmes. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01978.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

How neuropsychology informs our understanding of developmental disorders / Bruce F. PENNINGTON in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.72-78 Titre : How neuropsychology informs our understanding of developmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : Bruce F. PENNINGTON, Auteur Année de publication : 2009 Article en page(s) : p.72-78 Langues : Anglais (eng) Mots-clés : Developmental-cognitive-neuroscience plasticity molecular-genetics neural-network-models dyslexia neuropsychology Index. décimale : PER Périodiques Résumé : This review includes 1) an explanation of what neuropsychology is, 2) a brief history of how developmental cognitive neuroscience emerged from earlier neuropsychological approaches to understanding atypical development, 3) three recent examples that illustrate the benefits of this approach, 4) issues and challenges this approach must face, and 5) a forecast for the future of this approach. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01977.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] How neuropsychology informs our understanding of developmental disorders [Texte imprimé et/ou numérique] / Bruce F. PENNINGTON, Auteur . - 2009 . - p.72-78. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.72-78 Mots-clés : Developmental-cognitive-neuroscience plasticity molecular-genetics neural-network-models dyslexia neuropsychology Index. décimale : PER Périodiques Résumé : This review includes 1) an explanation of what neuropsychology is, 2) a brief history of how developmental cognitive neuroscience emerged from earlier neuropsychological approaches to understanding atypical development, 3) three recent examples that illustrate the benefits of this approach, 4) issues and challenges this approach must face, and 5) a forecast for the future of this approach. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01977.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Brain oscillations forever – neurophysiology in future research of child psychiatric problems / Aribert ROTHENBERGER in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.79-86 Titre : Brain oscillations forever – neurophysiology in future research of child psychiatric problems Type de document : Texte imprimé et/ou numérique Auteurs : Aribert ROTHENBERGER, Auteur Année de publication : 2009 Article en page(s) : p.79-86 Langues : Anglais (eng) Mots-clés : Neurophysiology children EEG brain-oscillations computational-neuropsychiatry Index. décimale : PER Périodiques Résumé : For decades neurophysiology has successfully contributed to research and clinical care in child psychiatry. Recently, methodological progress has led to a revival of interest in brain oscillations (i.e., a band of periodic neuronal frequencies with a wave-duration from milliseconds to several seconds which may code and decode information). These oscillations will nurture future information processing research during normal and pathological brain development, allowing us to investigate basic neuronal connectivity as well as interactions of brain systems and their modulation (e.g., by temporal neuronal synchronisation) as close correlates of behaviour and intermediate phenotypes from genes to behavioural variations. Especially, a systematic neurodynamic look at transitional processes from rest to stimulus-triggered goal-directed performance will aid behavioural understanding and guidance of children. Preliminary data suggest two separate oscillatory mechanisms in this respect. One is ongoing from pre- to post-stimulus processing and related to quantitative modification of behaviour, while another is merely related to qualitative effects of behaviour and reflects 'on-top' post-stimulus processing by temporal neuronal synchronisation of the oscillatory network in question. Suggested neurodynamic models may be tested in multilevel clinical experiments as well as in the framework of computational neuropsychiatry. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01994.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Brain oscillations forever – neurophysiology in future research of child psychiatric problems [Texte imprimé et/ou numérique] / Aribert ROTHENBERGER, Auteur . - 2009 . - p.79-86. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.79-86 Mots-clés : Neurophysiology children EEG brain-oscillations computational-neuropsychiatry Index. décimale : PER Périodiques Résumé : For decades neurophysiology has successfully contributed to research and clinical care in child psychiatry. Recently, methodological progress has led to a revival of interest in brain oscillations (i.e., a band of periodic neuronal frequencies with a wave-duration from milliseconds to several seconds which may code and decode information). These oscillations will nurture future information processing research during normal and pathological brain development, allowing us to investigate basic neuronal connectivity as well as interactions of brain systems and their modulation (e.g., by temporal neuronal synchronisation) as close correlates of behaviour and intermediate phenotypes from genes to behavioural variations. Especially, a systematic neurodynamic look at transitional processes from rest to stimulus-triggered goal-directed performance will aid behavioural understanding and guidance of children. Preliminary data suggest two separate oscillatory mechanisms in this respect. One is ongoing from pre- to post-stimulus processing and related to quantitative modification of behaviour, while another is merely related to qualitative effects of behaviour and reflects 'on-top' post-stimulus processing by temporal neuronal synchronisation of the oscillatory network in question. Suggested neurodynamic models may be tested in multilevel clinical experiments as well as in the framework of computational neuropsychiatry. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01994.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Childhood developmental disorders: an academic and clinical convergence point for psychiatry, neurology, psychology and pediatrics / Allan L. REISS in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.87-98 Titre : Childhood developmental disorders: an academic and clinical convergence point for psychiatry, neurology, psychology and pediatrics Type de document : Texte imprimé et/ou numérique Auteurs : Allan L. REISS, Auteur Année de publication : 2009 Article en page(s) : p.87-98 Langues : Anglais (eng) Mots-clés : Autism fragile-X-syndrome Rett-syndrome interdisciplinary-training developmental-disorder brain-development genetic-risk-factor neurogenetic-disorder academic-medicine clinical-neuroscience disciplinary-boundaries Index. décimale : PER Périodiques Résumé : Background: Significant advances in understanding brain development and behavior have not been accompanied by revisions of traditional academic structure. Disciplinary isolation and a lack of meaningful interdisciplinary opportunities are persistent barriers in academic medicine. To enhance clinical practice, research, and training for the next generation, academic centers will need to take bold steps that challenge traditional departmental boundaries. Such change is not only desirable but, in fact, necessary to bring about a truly innovative and more effective approach to treating disorders of the developing brain. Methods: I focus on developmental disorders as a convergence point for transcending traditional academic boundaries. First, the current taxonomy of developmental disorders is described with emphasis on how current diagnostic systems inadvertently hinder research progress. Second, I describe the clinical features of autism, a phenomenologically defined condition, and Rett and fragile X syndromes, neurogenetic diseases that are risk factors for autism. Finally, I describe how the fields of psychiatry, psychology, neurology, and pediatrics now have an unprecedented opportunity to promote an interdisciplinary approach to training, research, and clinical practice and, thus, advance a deeper understanding of developmental disorders. Results: Research focused on autism is increasingly demonstrating the heterogeneity of individuals diagnosed by DSM criteria. This heterogeneity hinders the ability of investigators to replicate research results as well as progress towards more effective, etiology-specific interventions. In contrast, fragile X and Rett syndromes are 'real' diseases for which advances in research are rapidly accelerating towards more disease-specific human treatment trials. Conclusions: A major paradigm shift is required to improve our ability to diagnose and treat individuals with developmental disorders. This paradigm shift must take place at all levels – training, research and clinical activity. As clinicians and scientists who are currently constrained by disciplinary-specific history and training, we must move towards redefining ourselves as clinical neuroscientists with shared interests and expertise that permit a more cohesive and effective approach to improving the lives of patients. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02046.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Childhood developmental disorders: an academic and clinical convergence point for psychiatry, neurology, psychology and pediatrics [Texte imprimé et/ou numérique] / Allan L. REISS, Auteur . - 2009 . - p.87-98. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.87-98 Mots-clés : Autism fragile-X-syndrome Rett-syndrome interdisciplinary-training developmental-disorder brain-development genetic-risk-factor neurogenetic-disorder academic-medicine clinical-neuroscience disciplinary-boundaries Index. décimale : PER Périodiques Résumé : Background: Significant advances in understanding brain development and behavior have not been accompanied by revisions of traditional academic structure. Disciplinary isolation and a lack of meaningful interdisciplinary opportunities are persistent barriers in academic medicine. To enhance clinical practice, research, and training for the next generation, academic centers will need to take bold steps that challenge traditional departmental boundaries. Such change is not only desirable but, in fact, necessary to bring about a truly innovative and more effective approach to treating disorders of the developing brain. Methods: I focus on developmental disorders as a convergence point for transcending traditional academic boundaries. First, the current taxonomy of developmental disorders is described with emphasis on how current diagnostic systems inadvertently hinder research progress. Second, I describe the clinical features of autism, a phenomenologically defined condition, and Rett and fragile X syndromes, neurogenetic diseases that are risk factors for autism. Finally, I describe how the fields of psychiatry, psychology, neurology, and pediatrics now have an unprecedented opportunity to promote an interdisciplinary approach to training, research, and clinical practice and, thus, advance a deeper understanding of developmental disorders. Results: Research focused on autism is increasingly demonstrating the heterogeneity of individuals diagnosed by DSM criteria. This heterogeneity hinders the ability of investigators to replicate research results as well as progress towards more effective, etiology-specific interventions. In contrast, fragile X and Rett syndromes are 'real' diseases for which advances in research are rapidly accelerating towards more disease-specific human treatment trials. Conclusions: A major paradigm shift is required to improve our ability to diagnose and treat individuals with developmental disorders. This paradigm shift must take place at all levels – training, research and clinical activity. As clinicians and scientists who are currently constrained by disciplinary-specific history and training, we must move towards redefining ourselves as clinical neuroscientists with shared interests and expertise that permit a more cohesive and effective approach to improving the lives of patients. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02046.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Intellectual disabilities and child psychiatry: looking to the future / Robert M. HODAPP in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.99-107 Titre : Intellectual disabilities and child psychiatry: looking to the future Type de document : Texte imprimé et/ou numérique Auteurs : Robert M. HODAPP, Auteur ; Elisabeth M. DYKENS, Auteur Année de publication : 2009 Article en page(s) : p.99-107 Langues : Anglais (eng) Mots-clés : Behavioral-phenotype gene–brain-behavior-relations GE-correlation demographics gender aging Index. décimale : PER Périodiques Résumé : We begin this article by examining the role of intellectual disabilities within child psychiatry, highlighting the relatively steady role of disabilities and the recent movement to examine behavior in specific genetic syndromes. We next propose five questions for future work. Questions relate to (1) specifying the nature of gene–brain–behavior connections; (2) delineating environmental effects and gene–environment interactions; (3) understanding behaviors, physical characteristics, health issues, and other personal characteristics by which children with intellectual disabilities influence others; (4) clarifying the roles of gender and aging in behavioral functioning; and (5) working to improve pharmacological, educational, and other interventions and supports for children and their families. Although great advances have occurred over the past 50 years, intellectual disability research lags behind other areas of child psychiatry; much remains to be discovered that might help these children. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02038.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Intellectual disabilities and child psychiatry: looking to the future [Texte imprimé et/ou numérique] / Robert M. HODAPP, Auteur ; Elisabeth M. DYKENS, Auteur . - 2009 . - p.99-107. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.99-107 Mots-clés : Behavioral-phenotype gene–brain-behavior-relations GE-correlation demographics gender aging Index. décimale : PER Périodiques Résumé : We begin this article by examining the role of intellectual disabilities within child psychiatry, highlighting the relatively steady role of disabilities and the recent movement to examine behavior in specific genetic syndromes. We next propose five questions for future work. Questions relate to (1) specifying the nature of gene–brain–behavior connections; (2) delineating environmental effects and gene–environment interactions; (3) understanding behaviors, physical characteristics, health issues, and other personal characteristics by which children with intellectual disabilities influence others; (4) clarifying the roles of gender and aging in behavioral functioning; and (5) working to improve pharmacological, educational, and other interventions and supports for children and their families. Although great advances have occurred over the past 50 years, intellectual disability research lags behind other areas of child psychiatry; much remains to be discovered that might help these children. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02038.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Autism and autism spectrum disorders: diagnostic issues for the coming decade / Fred R. VOLKMAR in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.108-115 Titre : Autism and autism spectrum disorders: diagnostic issues for the coming decade Type de document : Texte imprimé et/ou numérique Auteurs : Fred R. VOLKMAR, Auteur ; Ami KLIN, Auteur ; Matthew W. STATE, Auteur Année de publication : 2009 Article en page(s) : p.108-115 Langues : Anglais (eng) Mots-clés : Autism diagnosis PDD Index. décimale : PER Périodiques Résumé : A decade and a half have elapsed since DSM-IV and ICD-10 appeared. During this time the convergent definitions of autism and related disorders in these two diagnostic systems have stimulated tremendous research. In this brief review we summarize areas of progress and continuing controversy, including approaches to diagnosis in more cognitively able individuals on the autism spectrum, diagnosis in very young infants, the issue of subtypes, and the potential contribution of genetic research. The use of dimensional assessments has some advantages as do the insights from prospective studies. At this point it will be important to study not only causative factors but developmental processes disrupted in these disorders. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02010.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Autism and autism spectrum disorders: diagnostic issues for the coming decade [Texte imprimé et/ou numérique] / Fred R. VOLKMAR, Auteur ; Ami KLIN, Auteur ; Matthew W. STATE, Auteur . - 2009 . - p.108-115. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.108-115 Mots-clés : Autism diagnosis PDD Index. décimale : PER Périodiques Résumé : A decade and a half have elapsed since DSM-IV and ICD-10 appeared. During this time the convergent definitions of autism and related disorders in these two diagnostic systems have stimulated tremendous research. In this brief review we summarize areas of progress and continuing controversy, including approaches to diagnosis in more cognitively able individuals on the autism spectrum, diagnosis in very young infants, the issue of subtypes, and the potential contribution of genetic research. The use of dimensional assessments has some advantages as do the insights from prospective studies. At this point it will be important to study not only causative factors but developmental processes disrupted in these disorders. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02010.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Speaking genes or genes for speaking? Deciphering the genetics of speech and language / Elena L. GRIGORENKO in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.116-125 Titre : Speaking genes or genes for speaking? Deciphering the genetics of speech and language Type de document : Texte imprimé et/ou numérique Auteurs : Elena L. GRIGORENKO, Auteur Année de publication : 2009 Article en page(s) : p.116-125 Langues : Anglais (eng) Mots-clés : Disorders-of-spoken-and-written-language etiology componential-approach intercorrelations-and-interdependencies Index. décimale : PER Périodiques Résumé : Background: This article selectively reviews the status of the genetic research in the field of speech and language disorders. Methods: Major contributions to the field are selected, presented, and discussed. Results: The field presents itself through a variety of findings, characterized by both consistencies and inconsistencies. Conclusions: The last 30 + years of the field unequivocally testify to the importance of genetic factors in the acquisition of speech and language. However, the details of how these factors exert their influence are yet to be determined. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02006.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Speaking genes or genes for speaking? Deciphering the genetics of speech and language [Texte imprimé et/ou numérique] / Elena L. GRIGORENKO, Auteur . - 2009 . - p.116-125. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.116-125 Mots-clés : Disorders-of-spoken-and-written-language etiology componential-approach intercorrelations-and-interdependencies Index. décimale : PER Périodiques Résumé : Background: This article selectively reviews the status of the genetic research in the field of speech and language disorders. Methods: Major contributions to the field are selected, presented, and discussed. Results: The field presents itself through a variety of findings, characterized by both consistencies and inconsistencies. Conclusions: The last 30 + years of the field unequivocally testify to the importance of genetic factors in the acquisition of speech and language. However, the details of how these factors exert their influence are yet to be determined. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02006.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Developing ADHD / Eric TAYLOR in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.126-132 Titre : Developing ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Eric TAYLOR, Auteur Année de publication : 2009 Article en page(s) : p.126-132 Langues : Anglais (eng) Mots-clés : ADHD attention impulsiveness hyperkinetic taxonomy prevalence Index. décimale : PER Périodiques Résumé : Over the past 50 years the concept of attention deficit/hyperactivity disorder (ADHD) has developed from the notion of a specific form of brain dysfunction to that of a heterogeneous set of related behaviours. The great advances in genetics, neuroimaging and neuropsychiatry have made it one of the best understood forms of complex mental disturbance – but much remains to be done to translate understanding into practice. More effective treatment may come from identifying and treating more specific components of disorder and by a focus on identifying the factors determining course in the longer term so that they, as well as the core features of disorder, can become targets for intervention. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01999.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Developing ADHD [Texte imprimé et/ou numérique] / Eric TAYLOR, Auteur . - 2009 . - p.126-132. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.126-132 Mots-clés : ADHD attention impulsiveness hyperkinetic taxonomy prevalence Index. décimale : PER Périodiques Résumé : Over the past 50 years the concept of attention deficit/hyperactivity disorder (ADHD) has developed from the notion of a specific form of brain dysfunction to that of a heterogeneous set of related behaviours. The great advances in genetics, neuroimaging and neuropsychiatry have made it one of the best understood forms of complex mental disturbance – but much remains to be done to translate understanding into practice. More effective treatment may come from identifying and treating more specific components of disorder and by a focus on identifying the factors determining course in the longer term so that they, as well as the core features of disorder, can become targets for intervention. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01999.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Perspectives on oppositional defiant disorder, conduct disorder, and psychopathic features / Rolf LOEBER in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.133-142 Titre : Perspectives on oppositional defiant disorder, conduct disorder, and psychopathic features Type de document : Texte imprimé et/ou numérique Auteurs : Rolf LOEBER, Auteur ; Dustin A. PARDINI, Auteur ; Jeffrey D. BURKE, Auteur Année de publication : 2009 Article en page(s) : p.133-142 Langues : Anglais (eng) Mots-clés : Oppositional-defiant-disorder conduct-disorder psychopathy-development prevention treatment Index. décimale : PER Périodiques Résumé : This paper presents a few perspectives on oppositional defiant disorder (ODD), conduct disorder (CD), and early forms of psychopathy. The developmental changes and stability of each, and the interrelationship between the three conditions are reviewed, and correlates and predictors are highlighted. The paper also examines effective interventions for each of the three conditions and makes recommendations for future research. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02011.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694 [article] Perspectives on oppositional defiant disorder, conduct disorder, and psychopathic features [Texte imprimé et/ou numérique] / Rolf LOEBER, Auteur ; Dustin A. PARDINI, Auteur ; Jeffrey D. BURKE, Auteur . - 2009 . - p.133-142. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.133-142 Mots-clés : Oppositional-defiant-disorder conduct-disorder psychopathy-development prevention treatment Index. décimale : PER Périodiques Résumé : This paper presents a few perspectives on oppositional defiant disorder (ODD), conduct disorder (CD), and early forms of psychopathy. The developmental changes and stability of each, and the interrelationship between the three conditions are reviewed, and correlates and predictors are highlighted. The paper also examines effective interventions for each of the three conditions and makes recommendations for future research. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02011.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=694

Pediatric depression: is there evidence to improve evidence-based treatments? / David A. BRENT in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.143-152 Titre : Pediatric depression: is there evidence to improve evidence-based treatments? Type de document : Texte imprimé et/ou numérique Auteurs : David A. BRENT, Auteur ; Fadi T. MAALOUF, Auteur Année de publication : 2009 Article en page(s) : p.143-152 Langues : Anglais (eng) Mots-clés : Depression cognition development treatment intermediate-phenotype biomarker Index. décimale : PER Périodiques Résumé : Although there have been advances in our ability to treat child and adolescent depression, use of evidence-based treatments still results in many patients with residual symptoms. Advances in our understanding of cognitive, emotional, and ecological aspects of early-onset depression have the potential to lead to improvements in the assessment and treatment of depression. A search for endophenotypes, i.e., traits that are related to depression, mediate the familial transmission of depression, and are genetically determined, may help in understanding etiology and in personalizing treatment. However, advances in treatment may also come from the identification of biomarkers, i.e., modifiable neurocognitive, physiological, or biochemical indices that are correlated with, or mediate, treatment outcome. More effective treatments may emerge from being able to personalize interventions to the patient's cognitive, emotional, and developmental profile. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02037.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 [article] Pediatric depression: is there evidence to improve evidence-based treatments? [Texte imprimé et/ou numérique] / David A. BRENT, Auteur ; Fadi T. MAALOUF, Auteur . - 2009 . - p.143-152. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.143-152 Mots-clés : Depression cognition development treatment intermediate-phenotype biomarker Index. décimale : PER Périodiques Résumé : Although there have been advances in our ability to treat child and adolescent depression, use of evidence-based treatments still results in many patients with residual symptoms. Advances in our understanding of cognitive, emotional, and ecological aspects of early-onset depression have the potential to lead to improvements in the assessment and treatment of depression. A search for endophenotypes, i.e., traits that are related to depression, mediate the familial transmission of depression, and are genetically determined, may help in understanding etiology and in personalizing treatment. However, advances in treatment may also come from the identification of biomarkers, i.e., modifiable neurocognitive, physiological, or biochemical indices that are correlated with, or mediate, treatment outcome. More effective treatments may emerge from being able to personalize interventions to the patient's cognitive, emotional, and developmental profile. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02037.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695

Anxiety disorders / Rachel G. KLEIN in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.153-162 Titre : Anxiety disorders Type de document : Texte imprimé et/ou numérique Auteurs : Rachel G. KLEIN, Auteur Année de publication : 2009 Article en page(s) : p.153-162 Langues : Anglais (eng) Mots-clés : Anxiety-disorders normal-vs.-pathological-anxiety validity-of-child-anxiety-disorders need-for-precision-for-impairment ADHD hormones personality mediation Index. décimale : PER Périodiques Résumé : Because of their high prevalence and their negative long-term consequences, child anxiety disorders have become an important focus of interest. Whether pathological anxiety and normal fear are similar processes continues to be controversial. Comparative studies of child anxiety disorders are scarce, but there is some support for the current classification of anxiety disorders in children and adolescents, except for generalized anxiety disorder. The greatly differing rates of anxiety disorders in child population studies, and of specific disorders in clinical samples, inconsistent findings regarding course, and disparate placebo response rates all suggest a need for more precise, validated, criteria for symptoms, distress, and impairment. Several treatments have documented efficacy, and promising prevention efforts are encouraging. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02061.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 [article] Anxiety disorders [Texte imprimé et/ou numérique] / Rachel G. KLEIN, Auteur . - 2009 . - p.153-162. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.153-162 Mots-clés : Anxiety-disorders normal-vs.-pathological-anxiety validity-of-child-anxiety-disorders need-for-precision-for-impairment ADHD hormones personality mediation Index. décimale : PER Périodiques Résumé : Because of their high prevalence and their negative long-term consequences, child anxiety disorders have become an important focus of interest. Whether pathological anxiety and normal fear are similar processes continues to be controversial. Comparative studies of child anxiety disorders are scarce, but there is some support for the current classification of anxiety disorders in children and adolescents, except for generalized anxiety disorder. The greatly differing rates of anxiety disorders in child population studies, and of specific disorders in clinical samples, inconsistent findings regarding course, and disparate placebo response rates all suggest a need for more precise, validated, criteria for symptoms, distress, and impairment. Several treatments have documented efficacy, and promising prevention efforts are encouraging. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02061.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695

Perplexities and provocations of eating disorders / Katherine A. HALMI in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.163-169 Titre : Perplexities and provocations of eating disorders Type de document : Texte imprimé et/ou numérique Auteurs : Katherine A. HALMI, Auteur Année de publication : 2009 Article en page(s) : p.163-169 Langues : Anglais (eng) Mots-clés : Anorexia-nervosa bulimia-nervosa allostasis neurocircuitry Index. décimale : PER Périodiques Résumé : Background: Etiological hypotheses of eating disorders, anorexia nervosa and bulimia nervosa have not produced informative research for predictably effective treatment. Methods: The rationale for applying a model of allostasis, a dysregulation of reward circuits with activation of brain and hormonal stress responses to maintain apparent stability, is developed for eating disorders. Results: The neurotransmitter systems involved in the allostatic state of a reward system in anorexia nervosa and bulimia nervosa may be similar to those present in drug addiction. Conclusion: The biological vulnerabilities underlying the unique features of eating disorders should be intensively investigated with the advancing techniques in genetics and neuroimaging. Preventing chronicity with early diagnosis and adequate treatment before age 18 is necessary. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01983.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 [article] Perplexities and provocations of eating disorders [Texte imprimé et/ou numérique] / Katherine A. HALMI, Auteur . - 2009 . - p.163-169. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.163-169 Mots-clés : Anorexia-nervosa bulimia-nervosa allostasis neurocircuitry Index. décimale : PER Périodiques Résumé : Background: Etiological hypotheses of eating disorders, anorexia nervosa and bulimia nervosa have not produced informative research for predictably effective treatment. Methods: The rationale for applying a model of allostasis, a dysregulation of reward circuits with activation of brain and hormonal stress responses to maintain apparent stability, is developed for eating disorders. Results: The neurotransmitter systems involved in the allostatic state of a reward system in anorexia nervosa and bulimia nervosa may be similar to those present in drug addiction. Conclusion: The biological vulnerabilities underlying the unique features of eating disorders should be intensively investigated with the advancing techniques in genetics and neuroimaging. Preventing chronicity with early diagnosis and adequate treatment before age 18 is necessary. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01983.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695

The future of psychotherapy for mentally ill children and adolescents / John S. MARCH in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.170-179 Titre : The future of psychotherapy for mentally ill children and adolescents Type de document : Texte imprimé et/ou numérique Auteurs : John S. MARCH, Auteur Année de publication : 2009 Article en page(s) : p.170-179 Langues : Anglais (eng) Mots-clés : Psychotherapy CBT behavior-therapy cognitive-therapy brain-development development neuroscience physical-therapy internet psychopharmacology Index. décimale : PER Périodiques Résumé : Objective: Given striking advances in translational developmental neuroscience and its convergence with developmental psychopathology and developmental epidemiology, it is now clear that mental illnesses are best thought of as neurodevelopmental disorders. This simple fact has enormous implications for the nature and organization of psychotherapy for mentally ill children, adolescents and adults. Method: This article reviews the 'trajectory' of psychosocial interventions in pediatric psychiatry, and makes some general predictions about where this field is heading over the next several decades. Results: Driven largely by scientific advances in molecular, cellular and systems neuroscience, psychotherapy in the future will focus less on personal narratives and more on the developing brain. In place of disorders as intervention targets, modularized psychosocial treatment components derived from current cognitive-behavior therapies will target corresponding central nervous system (CNS) information processes and their functional behavioral consequences. Either preventive or rehabilitative, the goal of psychotherapy will be to promote development along typical developmental trajectories. In place of guilds, psychotherapy will be organized professionally much as physical therapy is organized today. As with other forms of increasingly personalized health care, internet-based delivery of psychotherapy will become commonplace. Conclusion: Informed by the new field of translational developmental neuroscience, psychotherapy in the future will take aim at the developing brain in a service delivery model that closely resembles the place and role of psychosocial interventions in the rest of medicine. Getting there will be, as they say, interesting. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02034.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 [article] The future of psychotherapy for mentally ill children and adolescents [Texte imprimé et/ou numérique] / John S. MARCH, Auteur . - 2009 . - p.170-179. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.170-179 Mots-clés : Psychotherapy CBT behavior-therapy cognitive-therapy brain-development development neuroscience physical-therapy internet psychopharmacology Index. décimale : PER Périodiques Résumé : Objective: Given striking advances in translational developmental neuroscience and its convergence with developmental psychopathology and developmental epidemiology, it is now clear that mental illnesses are best thought of as neurodevelopmental disorders. This simple fact has enormous implications for the nature and organization of psychotherapy for mentally ill children, adolescents and adults. Method: This article reviews the 'trajectory' of psychosocial interventions in pediatric psychiatry, and makes some general predictions about where this field is heading over the next several decades. Results: Driven largely by scientific advances in molecular, cellular and systems neuroscience, psychotherapy in the future will focus less on personal narratives and more on the developing brain. In place of disorders as intervention targets, modularized psychosocial treatment components derived from current cognitive-behavior therapies will target corresponding central nervous system (CNS) information processes and their functional behavioral consequences. Either preventive or rehabilitative, the goal of psychotherapy will be to promote development along typical developmental trajectories. In place of guilds, psychotherapy will be organized professionally much as physical therapy is organized today. As with other forms of increasingly personalized health care, internet-based delivery of psychotherapy will become commonplace. Conclusion: Informed by the new field of translational developmental neuroscience, psychotherapy in the future will take aim at the developing brain in a service delivery model that closely resembles the place and role of psychosocial interventions in the rest of medicine. Getting there will be, as they say, interesting. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02034.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695

Psychopharmacology: concepts and opinions about the use of stimulant medications / James M. SWANSON in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.180-193 Titre : Psychopharmacology: concepts and opinions about the use of stimulant medications Type de document : Texte imprimé et/ou numérique Auteurs : James M. SWANSON, Auteur ; Nora D. VOLKOW, Auteur Année de publication : 2009 Article en page(s) : p.180-193 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02062.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 [article] Psychopharmacology: concepts and opinions about the use of stimulant medications [Texte imprimé et/ou numérique] / James M. SWANSON, Auteur ; Nora D. VOLKOW, Auteur . - 2009 . - p.180-193. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.180-193 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02062.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695

Community intervention and public policy in the prevention of antisocial behavior / Kenneth A. DODGE in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.194-200 Titre : Community intervention and public policy in the prevention of antisocial behavior Type de document : Texte imprimé et/ou numérique Auteurs : Kenneth A. DODGE, Auteur Année de publication : 2009 Article en page(s) : p.194-200 Langues : Anglais (eng) Mots-clés : Antisocial-behavior community-intervention prevention population-prevalence Index. décimale : PER Périodiques Résumé : As academic clinical science moves to community intervention to achieve impact on population prevalence of antisocial behavior disorders, exciting potential is tempered by realistic caution. Three kinds of efforts are noted. First, individual evidence-based therapies are being implemented at scale. Difficulties in high-fidelity implementation are noted, and the unlikelihood of population impact is highlighted. Second, communities are receiving new resources to support individuals, although connecting community resources to highest-risk individuals is difficult. Third, community factors are being targeted for change through policy reform, with mixed results. As the field moves in this direction, the importance of adhering to principles of scientific rigor and empirical evidence is emphasized, to keep scientist-practitioners from overstepping their bounds. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01985.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 [article] Community intervention and public policy in the prevention of antisocial behavior [Texte imprimé et/ou numérique] / Kenneth A. DODGE, Auteur . - 2009 . - p.194-200. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.194-200 Mots-clés : Antisocial-behavior community-intervention prevention population-prevalence Index. décimale : PER Périodiques Résumé : As academic clinical science moves to community intervention to achieve impact on population prevalence of antisocial behavior disorders, exciting potential is tempered by realistic caution. Three kinds of efforts are noted. First, individual evidence-based therapies are being implemented at scale. Difficulties in high-fidelity implementation are noted, and the unlikelihood of population impact is highlighted. Second, communities are receiving new resources to support individuals, although connecting community resources to highest-risk individuals is difficult. Third, community factors are being targeted for change through policy reform, with mixed results. As the field moves in this direction, the importance of adhering to principles of scientific rigor and empirical evidence is emphasized, to keep scientist-practitioners from overstepping their bounds. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01985.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695