Assessing Advanced Theory of Mind in Children and Adolescents with High-Functioning Autism: The Spanish Version of the Stories of Everyday Life / Sara LERA-MIGUEL in Journal of Autism and Developmental Disorders, 46-1 (January 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.294-304 Titre : Assessing Advanced Theory of Mind in Children and Adolescents with High-Functioning Autism: The Spanish Version of the Stories of Everyday Life Type de document : texte imprimé Auteurs : Sara LERA-MIGUEL, Auteur ; Mireia ROSA, Auteur ; Olga PUIG, Auteur ; Nils KALAND, Auteur ; Luisa LÁZARO, Auteur ; Josefina CASTRO-FORNIELES, Auteur ; Rosa CALVO, Auteur Année de publication : 2016 Article en page(s) : p.294-304 Langues : Anglais (eng) Mots-clés : High functioning autism spectrum disorders  Child Adolescent  Theory of mind  Validation study Index. décimale : PER Périodiques Résumé : Most individuals with autism spectrum disorders often fail in tasks of theory of mind (ToM). However, those with normal intellectual functioning known as high functioning ASD (HF-ASD) sometimes succeed in mentalizing inferences. Some tools have been developed to more accurately test their ToM abilities. The aims of this study were to examine the psychometric properties of the Spanish version of Stories of Everyday Life Test (SEL) in a sample of 29 children and adolescents with HF-ASD and 25 typically developing controls and to compare their performance. The Spanish-SEL demonstrated good internal consistency, strong convergence with clinical severity and another ToM test, and adequate discriminant validity from intellectual capability and age, identifying the condition of 70 % of participants. En ligne : http://dx.doi.org/10.1007/s10803-015-2585-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Assessing Advanced Theory of Mind in Children and Adolescents with High-Functioning Autism: The Spanish Version of the Stories of Everyday Life [texte imprimé] / Sara LERA-MIGUEL, Auteur ; Mireia ROSA, Auteur ; Olga PUIG, Auteur ; Nils KALAND, Auteur ; Luisa LÁZARO, Auteur ; Josefina CASTRO-FORNIELES, Auteur ; Rosa CALVO, Auteur . - 2016 . - p.294-304. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.294-304 Mots-clés : High functioning autism spectrum disorders  Child Adolescent  Theory of mind  Validation study Index. décimale : PER Périodiques Résumé : Most individuals with autism spectrum disorders often fail in tasks of theory of mind (ToM). However, those with normal intellectual functioning known as high functioning ASD (HF-ASD) sometimes succeed in mentalizing inferences. Some tools have been developed to more accurately test their ToM abilities. The aims of this study were to examine the psychometric properties of the Spanish version of Stories of Everyday Life Test (SEL) in a sample of 29 children and adolescents with HF-ASD and 25 typically developing controls and to compare their performance. The Spanish-SEL demonstrated good internal consistency, strong convergence with clinical severity and another ToM test, and adequate discriminant validity from intellectual capability and age, identifying the condition of 70 % of participants. En ligne : http://dx.doi.org/10.1007/s10803-015-2585-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Brain structural trajectories in youth at familial risk for schizophrenia or bipolar disorder according to development of psychosis spectrum symptoms / Gisela SUGRANYES in Journal of Child Psychology and Psychiatry, 62-6 (June 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-6 (June 2021) . - p.780-789 Titre : Brain structural trajectories in youth at familial risk for schizophrenia or bipolar disorder according to development of psychosis spectrum symptoms Type de document : texte imprimé Auteurs : Gisela SUGRANYES, Auteur ; Elena DE LA SERNA, Auteur ; Daniel ILZARBE, Auteur ; Jose Carlos PARIENTE, Auteur ; Roger BORRAS, Auteur ; Soledad ROMERO, Auteur ; Mireia ROSA, Auteur ; Inmaculada BAEZA, Auteur ; Maria Dolores MORENO, Auteur ; Miguel BERNARDO, Auteur ; Eduard VIETA, Auteur ; Josefina CASTRO-FORNIELES, Auteur Article en page(s) : p.780-789 Langues : Anglais (eng) Mots-clés : Adolescent  Bipolar Disorder/diagnostic imaging  Brain/diagnostic imaging  Cross-Sectional Studies  Genetic Predisposition to Disease  Humans  Magnetic Resonance Imaging  Psychotic Disorders/diagnostic imaging  Schizophrenia/diagnostic imaging/genetics  High-risk studies  bipolar  psychosis  schizophrenia  structural MRI Index. décimale : PER Périodiques Résumé : BACKGROUND: The evaluation of child and adolescent offspring of patients with schizophrenia (SzO) or bipolar disorder (BpO) may help understand changes taking place in the brain in individuals at heightened risk for disease during a key developmental period. METHODS: One hundred twenty-eight individuals (33 SzO and 46 BpO, considered jointly as 'Familial High Risk' (FHR), and 49 controls) aged 6-17 years underwent clinical, cognitive and neuroimaging assessment at baseline, 2- and 4-year follow-up. Twenty FHR participants (11 SzO and 9 BpO) developed psychotic spectrum symptoms during follow-up, while 59 FHR participants did not. Magnetic resonance imaging was performed on a 3Tesla scanner; cortical surface reconstruction was applied to measure cortical thickness, surface area and grey matter volume. RESULTS: FHR participants who developed psychotic spectrum symptoms over time showed greater time-related mean cortical thinning than those who did not and than controls. By subgroups, this effect was present in both BpO and SzO in the occipital cortex. At baseline, FHR participants who developed psychotic spectrum symptoms over time had smaller total surface area and grey matter volume than those who did not and than controls. Over time, all FHR participants showed less longitudinal decrease in surface area than controls. In those who developed psychotic spectrum symptoms over time, this effect was driven by BpO, while in those who did not, this was due to SzO, who also showed less grey matter volume reduction. CONCLUSION: The emergence of psychotic spectrum symptoms in FHR was indexed by smaller cross-sectional surface area and progressive cortical thinning. Relative preservation of surface area over time may signal different processes according to familial risk. These findings lay the foundation for future studies aimed at stratification of FHR youth. En ligne : http://dx.doi.org/10.1111/jcpp.13321 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Brain structural trajectories in youth at familial risk for schizophrenia or bipolar disorder according to development of psychosis spectrum symptoms [texte imprimé] / Gisela SUGRANYES, Auteur ; Elena DE LA SERNA, Auteur ; Daniel ILZARBE, Auteur ; Jose Carlos PARIENTE, Auteur ; Roger BORRAS, Auteur ; Soledad ROMERO, Auteur ; Mireia ROSA, Auteur ; Inmaculada BAEZA, Auteur ; Maria Dolores MORENO, Auteur ; Miguel BERNARDO, Auteur ; Eduard VIETA, Auteur ; Josefina CASTRO-FORNIELES, Auteur . - p.780-789. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-6 (June 2021) . - p.780-789 Mots-clés : Adolescent  Bipolar Disorder/diagnostic imaging  Brain/diagnostic imaging  Cross-Sectional Studies  Genetic Predisposition to Disease  Humans  Magnetic Resonance Imaging  Psychotic Disorders/diagnostic imaging  Schizophrenia/diagnostic imaging/genetics  High-risk studies  bipolar  psychosis  schizophrenia  structural MRI Index. décimale : PER Périodiques Résumé : BACKGROUND: The evaluation of child and adolescent offspring of patients with schizophrenia (SzO) or bipolar disorder (BpO) may help understand changes taking place in the brain in individuals at heightened risk for disease during a key developmental period. METHODS: One hundred twenty-eight individuals (33 SzO and 46 BpO, considered jointly as 'Familial High Risk' (FHR), and 49 controls) aged 6-17 years underwent clinical, cognitive and neuroimaging assessment at baseline, 2- and 4-year follow-up. Twenty FHR participants (11 SzO and 9 BpO) developed psychotic spectrum symptoms during follow-up, while 59 FHR participants did not. Magnetic resonance imaging was performed on a 3Tesla scanner; cortical surface reconstruction was applied to measure cortical thickness, surface area and grey matter volume. RESULTS: FHR participants who developed psychotic spectrum symptoms over time showed greater time-related mean cortical thinning than those who did not and than controls. By subgroups, this effect was present in both BpO and SzO in the occipital cortex. At baseline, FHR participants who developed psychotic spectrum symptoms over time had smaller total surface area and grey matter volume than those who did not and than controls. Over time, all FHR participants showed less longitudinal decrease in surface area than controls. In those who developed psychotic spectrum symptoms over time, this effect was driven by BpO, while in those who did not, this was due to SzO, who also showed less grey matter volume reduction. CONCLUSION: The emergence of psychotic spectrum symptoms in FHR was indexed by smaller cross-sectional surface area and progressive cortical thinning. Relative preservation of surface area over time may signal different processes according to familial risk. These findings lay the foundation for future studies aimed at stratification of FHR youth. En ligne : http://dx.doi.org/10.1111/jcpp.13321 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Broad Cognitive Profile in Children and Adolescents with HF-ASD and in Their Siblings: Widespread Underperformance and its Clinical and Adaptive Correlates / Mireia ROSA in Journal of Autism and Developmental Disorders, 47-7 (July 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2153-2162 Titre : Broad Cognitive Profile in Children and Adolescents with HF-ASD and in Their Siblings: Widespread Underperformance and its Clinical and Adaptive Correlates Type de document : texte imprimé Auteurs : Mireia ROSA, Auteur ; Olga PUIG, Auteur ; Luisa LÁZARO, Auteur ; Virginia VALLÉS, Auteur ; Sara LERA, Auteur ; Vanessa SANCHEZ-GISTAU, Auteur ; Rosa CALVO, Auteur Article en page(s) : p.2153-2162 Langues : Anglais (eng) Mots-clés : High-functioning autism spectrum disorder  Children and adolescents  Neuropsychology  Adaptive functioning  Siblings Index. décimale : PER Périodiques Résumé : Despite evidence supporting the presence of cognitive deficits in children and adolescents with high-functioning autism spectrum disorder (HF-ASD), the nature of these deficits and their clinical and adaptive correlates remain unclear. Moreover, there are few cognitive studies of ASD siblings as a high risk population. We compared 50 children and adolescents with HF-ASD, 22 unaffected siblings of the HF-ASD sample and 34 community controls using an extensive neuropsychological battery. Planning, cognitive flexibility, verbal and working memory, visual local–global processing and emotion recognition are impaired in HF-ASD. Worse cognitive performance, especially in verbal and working memory, was significantly correlated with more severe symptoms and poorer adaptive functioning, also when controlling for intelligence quotient. Results in siblings may suggest an intermediate profile. En ligne : https://doi.org/10.1007/s10803-017-3137-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=314 [article] Broad Cognitive Profile in Children and Adolescents with HF-ASD and in Their Siblings: Widespread Underperformance and its Clinical and Adaptive Correlates [texte imprimé] / Mireia ROSA, Auteur ; Olga PUIG, Auteur ; Luisa LÁZARO, Auteur ; Virginia VALLÉS, Auteur ; Sara LERA, Auteur ; Vanessa SANCHEZ-GISTAU, Auteur ; Rosa CALVO, Auteur . - p.2153-2162. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2153-2162 Mots-clés : High-functioning autism spectrum disorder  Children and adolescents  Neuropsychology  Adaptive functioning  Siblings Index. décimale : PER Périodiques Résumé : Despite evidence supporting the presence of cognitive deficits in children and adolescents with high-functioning autism spectrum disorder (HF-ASD), the nature of these deficits and their clinical and adaptive correlates remain unclear. Moreover, there are few cognitive studies of ASD siblings as a high risk population. We compared 50 children and adolescents with HF-ASD, 22 unaffected siblings of the HF-ASD sample and 34 community controls using an extensive neuropsychological battery. Planning, cognitive flexibility, verbal and working memory, visual local–global processing and emotion recognition are impaired in HF-ASD. Worse cognitive performance, especially in verbal and working memory, was significantly correlated with more severe symptoms and poorer adaptive functioning, also when controlling for intelligence quotient. Results in siblings may suggest an intermediate profile. En ligne : https://doi.org/10.1007/s10803-017-3137-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=314

Socioeconomic status and intelligence quotient as predictors of psychiatric disorders in children and adolescents with high-functioning autism spectrum disorder and in their siblings / Mireia ROSA in Autism, 20-8 (November 2016)  

Public ISBD [article]  inAutism > 20-8 (November 2016) . - p.963-972 Titre : Socioeconomic status and intelligence quotient as predictors of psychiatric disorders in children and adolescents with high-functioning autism spectrum disorder and in their siblings Type de document : texte imprimé Auteurs : Mireia ROSA, Auteur ; Olga PUIG, Auteur ; Luisa LÁZARO, Auteur ; Rosa CALVO, Auteur Article en page(s) : p.963-972 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  comorbidity  intelligence quotient  siblings  socioeconomic status Index. décimale : PER Périodiques Résumé : Previous studies have shown high rates of comorbid disorders in children and adolescents with autism spectrum disorder, but failed to compare them with general population and few of them have identified predictors of comorbidity. This study compared the rates of psychiatric disorders in 50 children and adolescents with autism spectrum disorder, 24 of their siblings, 32 controls from general population and 22 of their siblings. Children and adolescent with autism spectrum disorder and their siblings had higher rates of attention deficit and hyperactivity disorder compared to controls. Lower socioeconomic status and intelligence quotient were the main risk factors. The contribution of socioeconomic status and intelligence quotient to increase the risk of developing comorbidity in autism spectrum disorder and psychopathology in their siblings deserves further study. En ligne : http://dx.doi.org/10.1177/1362361315617881 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] Socioeconomic status and intelligence quotient as predictors of psychiatric disorders in children and adolescents with high-functioning autism spectrum disorder and in their siblings [texte imprimé] / Mireia ROSA, Auteur ; Olga PUIG, Auteur ; Luisa LÁZARO, Auteur ; Rosa CALVO, Auteur . - p.963-972. Langues : Anglais (eng) in Autism > 20-8 (November 2016) . - p.963-972 Mots-clés : autism spectrum disorder  comorbidity  intelligence quotient  siblings  socioeconomic status Index. décimale : PER Périodiques Résumé : Previous studies have shown high rates of comorbid disorders in children and adolescents with autism spectrum disorder, but failed to compare them with general population and few of them have identified predictors of comorbidity. This study compared the rates of psychiatric disorders in 50 children and adolescents with autism spectrum disorder, 24 of their siblings, 32 controls from general population and 22 of their siblings. Children and adolescent with autism spectrum disorder and their siblings had higher rates of attention deficit and hyperactivity disorder compared to controls. Lower socioeconomic status and intelligence quotient were the main risk factors. The contribution of socioeconomic status and intelligence quotient to increase the risk of developing comorbidity in autism spectrum disorder and psychopathology in their siblings deserves further study. En ligne : http://dx.doi.org/10.1177/1362361315617881 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

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