Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples / Kit K. ELAM in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.82-91 Titre : Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples Type de document : Texte imprimé et/ou numérique Auteurs : Kit K. ELAM, Auteur ; Kaitlin E. BOUNTRESS, Auteur ; Thao HA, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Fazil ALIEV, Auteur ; Danielle M. DICK, Auteur ; Kathryn LEMERY-CHALFANT, Auteur Article en page(s) : p.82-91 Langues : Anglais (eng) Mots-clés : adolescence  alcohol use  externalizing  longitudinal  polygenic Index. décimale : PER Périodiques Résumé : Externalizing behavior in early adolescence is associated with alcohol use in adolescence and early adulthood and these behaviors often emerge as part of a developmental sequence. This pattern can be the result of heterotypic continuity, in which different behaviors emerge over time based on an underlying shared etiology. In particular, there is largely a shared genetic etiology underlying externalizing and substance use behaviors. We examined whether polygenic risk for alcohol use disorder predicted (1) externalizing behavior in early adolescence and alcohol use in adolescence in the Early Steps Multisite sample and (2) externalizing behavior in adolescence and alcohol use in early adulthood in the Project Alliance 1 (PAL1) sample. We examined associations separately for African Americans and European Americans. When examining European Americans in the Early Steps sample, greater polygenic risk was associated with externalizing behavior in early adolescence. In European Americans in PAL1, we found greater polygenic risk was associated with alcohol use in early adulthood. Effects were largely absent in African Americans in both samples. Results imply that genetic predisposition for alcohol use disorder may increase risk for externalizing and alcohol use as these behaviors emerge developmentally. En ligne : https://dx.doi.org/10.1017/S0954579422000980 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Developmental genetic effects on externalizing behavior and alcohol use: Examination across two longitudinal samples [Texte imprimé et/ou numérique] / Kit K. ELAM, Auteur ; Kaitlin E. BOUNTRESS, Auteur ; Thao HA, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Fazil ALIEV, Auteur ; Danielle M. DICK, Auteur ; Kathryn LEMERY-CHALFANT, Auteur . - p.82-91. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.82-91 Mots-clés : adolescence  alcohol use  externalizing  longitudinal  polygenic Index. décimale : PER Périodiques Résumé : Externalizing behavior in early adolescence is associated with alcohol use in adolescence and early adulthood and these behaviors often emerge as part of a developmental sequence. This pattern can be the result of heterotypic continuity, in which different behaviors emerge over time based on an underlying shared etiology. In particular, there is largely a shared genetic etiology underlying externalizing and substance use behaviors. We examined whether polygenic risk for alcohol use disorder predicted (1) externalizing behavior in early adolescence and alcohol use in adolescence in the Early Steps Multisite sample and (2) externalizing behavior in adolescence and alcohol use in early adulthood in the Project Alliance 1 (PAL1) sample. We examined associations separately for African Americans and European Americans. When examining European Americans in the Early Steps sample, greater polygenic risk was associated with externalizing behavior in early adolescence. In European Americans in PAL1, we found greater polygenic risk was associated with alcohol use in early adulthood. Effects were largely absent in African Americans in both samples. Results imply that genetic predisposition for alcohol use disorder may increase risk for externalizing and alcohol use as these behaviors emerge developmentally. En ligne : https://dx.doi.org/10.1017/S0954579422000980 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

Examining protective factors for substance use problems and self-harm behavior during adolescence: A longitudinal co-twin control study / Lauren O’REILLY in Development and Psychopathology, 34-5 (December 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-5 (December 2022) . - p.1781-1802 Titre : Examining protective factors for substance use problems and self-harm behavior during adolescence: A longitudinal co-twin control study Type de document : Texte imprimé et/ou numérique Auteurs : Lauren O’REILLY, Auteur ; Kit K. ELAM, Auteur ; Patrick D. QUINN, Auteur ; Sydney ADAMS, Auteur ; Marianne G. CHIRICA, Auteur ; E. David KLONSKY, Auteur ; Erik PETTERSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Henrik LARSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Brian D’ONOFRIO, Auteur Article en page(s) : p.1781-1802 Langues : Anglais (eng) Mots-clés : adolescence  co-twin control  longitudinal  self-harm behavior  substance use Index. décimale : PER Périodiques Résumé : Sports participation, physical activity, and friendship quality are theorized to have protective effects on the developmental emergence of substance use and self-harm behavior in adolescence, but existing research has been mixed. This ambiguity could reflect, in part, the potential for confounding of observed associations by genetic and environmental factors, which previous research has been unable to rigorously rule out. We used data from the prospective, population-based Child and Adolescent Twin Study in Sweden (n = 18,234 born 1994 “2001) and applied a co-twin control design to account for potential genetic and environmental confounding of sports participation, physical activity, and friendship quality (assessed at age 15) as presumed protective factors for adolescent substance use and self-harm behavior (assessed at age 18). While confidence intervals widened to include the null in numerous co-twin control analyses adjusting for childhood psychopathology, parent-reported sports participation and twin-reported positive friendship quality were associated with increased odds of alcohol problems and nicotine use. However, parent-reported sports participation, twin-reported physical activity, and twin-reported friendship quality were associated with decreased odds of self-harm behavior. The findings provide a more nuanced understanding of the risks and benefits of putative protective factors for risky behaviors that emerge during adolescence. En ligne : http://dx.doi.org/10.1017/S0954579422000724 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 [article] Examining protective factors for substance use problems and self-harm behavior during adolescence: A longitudinal co-twin control study [Texte imprimé et/ou numérique] / Lauren O’REILLY, Auteur ; Kit K. ELAM, Auteur ; Patrick D. QUINN, Auteur ; Sydney ADAMS, Auteur ; Marianne G. CHIRICA, Auteur ; E. David KLONSKY, Auteur ; Erik PETTERSSON, Auteur ; Sebastian LUNDSTROM, Auteur ; Henrik LARSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Brian D’ONOFRIO, Auteur . - p.1781-1802. Langues : Anglais (eng) in Development and Psychopathology > 34-5 (December 2022) . - p.1781-1802 Mots-clés : adolescence  co-twin control  longitudinal  self-harm behavior  substance use Index. décimale : PER Périodiques Résumé : Sports participation, physical activity, and friendship quality are theorized to have protective effects on the developmental emergence of substance use and self-harm behavior in adolescence, but existing research has been mixed. This ambiguity could reflect, in part, the potential for confounding of observed associations by genetic and environmental factors, which previous research has been unable to rigorously rule out. We used data from the prospective, population-based Child and Adolescent Twin Study in Sweden (n = 18,234 born 1994 “2001) and applied a co-twin control design to account for potential genetic and environmental confounding of sports participation, physical activity, and friendship quality (assessed at age 15) as presumed protective factors for adolescent substance use and self-harm behavior (assessed at age 18). While confidence intervals widened to include the null in numerous co-twin control analyses adjusting for childhood psychopathology, parent-reported sports participation and twin-reported positive friendship quality were associated with increased odds of alcohol problems and nicotine use. However, parent-reported sports participation, twin-reported physical activity, and twin-reported friendship quality were associated with decreased odds of self-harm behavior. The findings provide a more nuanced understanding of the risks and benefits of putative protective factors for risky behaviors that emerge during adolescence. En ligne : http://dx.doi.org/10.1017/S0954579422000724 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492

Genotype?environment correlation by intervention effects underlying middle childhood peer rejection and associations with adolescent marijuana use / Kit K. ELAM in Development and Psychopathology, 34-1 (February 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-1 (February 2022) . - p.171-182 Titre : Genotype?environment correlation by intervention effects underlying middle childhood peer rejection and associations with adolescent marijuana use Type de document : Texte imprimé et/ou numérique Auteurs : Kit K. ELAM, Auteur ; Sierra CLIFFORD, Auteur ; Ariana RUOF, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Kathryn LEMERY-CHALFANT, Auteur Article en page(s) : p.171-182 Langues : Anglais (eng) Mots-clés : gene?environment correlation  marijuana use  middle childhood  peer rejection  time-varying effect modeling Index. décimale : PER Périodiques Résumé : Aggressive behavior in middle childhood can contribute to peer rejection, subsequently increasing risk for substance use in adolescence. However, the quality of peer relationships a child experiences can be associated with his or her genetic predisposition, a genotype?environment correlation (rGE). In addition, recent evidence indicates that psychosocial preventive interventions can buffer genetic predispositions for negative behavior. The current study examined associations between polygenic risk for aggression, aggressive behavior, and peer rejection from 8.5 to 10.5 years, and the subsequent influence of peer rejection on marijuana use in adolescence (n = 515; 256 control, 259 intervention). Associations were examined separately in control and intervention groups for children of families who participated in a randomized controlled trial of the family-based preventive intervention, the Family Check-Up . Using time-varying effect modeling (TVEM), polygenic risk for aggression was associated with peer rejection from approximately age 8.50 to 9.50 in the control group but no associations were present in the intervention group. Subsequent analyses showed peer rejection mediated the association between polygenic risk for aggression and adolescent marijuana use in the control group. The role of rGEs in middle childhood peer processes and implications for preventive intervention programs for adolescent substance use are discussed. En ligne : http://dx.doi.org/10.1017/s0954579420001066 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Genotype?environment correlation by intervention effects underlying middle childhood peer rejection and associations with adolescent marijuana use [Texte imprimé et/ou numérique] / Kit K. ELAM, Auteur ; Sierra CLIFFORD, Auteur ; Ariana RUOF, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Kathryn LEMERY-CHALFANT, Auteur . - p.171-182. Langues : Anglais (eng) in Development and Psychopathology > 34-1 (February 2022) . - p.171-182 Mots-clés : gene?environment correlation  marijuana use  middle childhood  peer rejection  time-varying effect modeling Index. décimale : PER Périodiques Résumé : Aggressive behavior in middle childhood can contribute to peer rejection, subsequently increasing risk for substance use in adolescence. However, the quality of peer relationships a child experiences can be associated with his or her genetic predisposition, a genotype?environment correlation (rGE). In addition, recent evidence indicates that psychosocial preventive interventions can buffer genetic predispositions for negative behavior. The current study examined associations between polygenic risk for aggression, aggressive behavior, and peer rejection from 8.5 to 10.5 years, and the subsequent influence of peer rejection on marijuana use in adolescence (n = 515; 256 control, 259 intervention). Associations were examined separately in control and intervention groups for children of families who participated in a randomized controlled trial of the family-based preventive intervention, the Family Check-Up . Using time-varying effect modeling (TVEM), polygenic risk for aggression was associated with peer rejection from approximately age 8.50 to 9.50 in the control group but no associations were present in the intervention group. Subsequent analyses showed peer rejection mediated the association between polygenic risk for aggression and adolescent marijuana use in the control group. The role of rGEs in middle childhood peer processes and implications for preventive intervention programs for adolescent substance use are discussed. En ligne : http://dx.doi.org/10.1017/s0954579420001066 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Marital stress and children's externalizing behavior as predictors of mothers’ and fathers’ parenting / Kit K. ELAM in Development and Psychopathology, 29-4 (October 2017)  

Public ISBD [article]  inDevelopment and Psychopathology > 29-4 (October 2017) . - p.1305-1318 Titre : Marital stress and children's externalizing behavior as predictors of mothers’ and fathers’ parenting Type de document : Texte imprimé et/ou numérique Auteurs : Kit K. ELAM, Auteur ; Laurie A. CHASSIN, Auteur ; Nancy EISENBERG, Auteur ; Tracy L. SPINRAD, Auteur Article en page(s) : p.1305-1318 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Previous research suggests that mothers’ and fathers’ parenting may be differentially influenced by marital and child factors within the family. Some research indicates that marital stress is more influential in fathers’ than mothers’ parenting, whereas other research shows that children's difficult behavior preferentially affects mothers’ parenting. The present study examined marital stress and children's externalizing behavior in middle childhood as predictors of mothers’ versus fathers’ consistency, monitoring, and support and care in early adolescence, and the subsequent associations of these parenting behaviors with externalizing behavior 1.5 years later. Pathways were examined within a longitudinal mediation model testing for moderation by parent gender (N = 276 mothers, N = 229 fathers). Children's externalizing behavior in middle childhood was found to more strongly inversely predict mothers’ versus fathers’ monitoring in early adolescence. In contrast, marital stress more strongly predicted low monitoring for fathers than for mothers. Regardless of parent gender, marital stress predicted lower levels of parental consistency, and children's externalizing behavior predicted lower levels of parental support. Mothers’ monitoring and fathers’ support in early adolescence predicted lower levels of externalizing behavior 1.5 years later. The results are discussed with respect to family transactions relative to parent gender and implications for intervention. En ligne : http://dx.doi.org/10.1017/s0954579416001322 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312 [article] Marital stress and children's externalizing behavior as predictors of mothers’ and fathers’ parenting [Texte imprimé et/ou numérique] / Kit K. ELAM, Auteur ; Laurie A. CHASSIN, Auteur ; Nancy EISENBERG, Auteur ; Tracy L. SPINRAD, Auteur . - p.1305-1318. Langues : Anglais (eng) in Development and Psychopathology > 29-4 (October 2017) . - p.1305-1318 Index. décimale : PER Périodiques Résumé : Abstract Previous research suggests that mothers’ and fathers’ parenting may be differentially influenced by marital and child factors within the family. Some research indicates that marital stress is more influential in fathers’ than mothers’ parenting, whereas other research shows that children's difficult behavior preferentially affects mothers’ parenting. The present study examined marital stress and children's externalizing behavior in middle childhood as predictors of mothers’ versus fathers’ consistency, monitoring, and support and care in early adolescence, and the subsequent associations of these parenting behaviors with externalizing behavior 1.5 years later. Pathways were examined within a longitudinal mediation model testing for moderation by parent gender (N = 276 mothers, N = 229 fathers). Children's externalizing behavior in middle childhood was found to more strongly inversely predict mothers’ versus fathers’ monitoring in early adolescence. In contrast, marital stress more strongly predicted low monitoring for fathers than for mothers. Regardless of parent gender, marital stress predicted lower levels of parental consistency, and children's externalizing behavior predicted lower levels of parental support. Mothers’ monitoring and fathers’ support in early adolescence predicted lower levels of externalizing behavior 1.5 years later. The results are discussed with respect to family transactions relative to parent gender and implications for intervention. En ligne : http://dx.doi.org/10.1017/s0954579416001322 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312

Polygenic risk, family cohesion, and adolescent aggression in Mexican American and European American families: Developmental pathways to alcohol use / Kit K. ELAM in Development and Psychopathology, 30-5 (December 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-5 (December 2018) . - p.1715-1728 Titre : Polygenic risk, family cohesion, and adolescent aggression in Mexican American and European American families: Developmental pathways to alcohol use Type de document : Texte imprimé et/ou numérique Auteurs : Kit K. ELAM, Auteur ; Laurie A. CHASSIN, Auteur ; Danielle PANDIKA, Auteur Article en page(s) : p.1715-1728 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Poor family cohesion and elevated adolescent aggression are associated with greater alcohol use in adolescence and early adulthood. In addition, evocative gene–environment correlations (rGEs) can underlie the interplay between offspring characteristics and negative family functioning, contributing to substance use. Gene–environment interplay has rarely been examined in racial/ethnic minority populations. The current study examined adolescents’ polygenic risk scores for aggression in evocative rGEs underlying aggression and family cohesion during adolescence, their contributions to alcohol use in early adulthood (n = 479), and differences between Mexican American and European American subsamples. Results suggest an evocative rGE between polygenic risk scores, aggression, and low family cohesion, with aggression contributing to low family cohesion over time. Greater family cohesion was associated with lower levels of alcohol use in early adulthood and this association was stronger for Mexican American adolescents compared to European American adolescents. Results are discussed with respect to integration of culture and racial/ethnic minority samples into genetic research and implications for alcohol use. En ligne : http://dx.doi.org/10.1017/S0954579418000901 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] Polygenic risk, family cohesion, and adolescent aggression in Mexican American and European American families: Developmental pathways to alcohol use [Texte imprimé et/ou numérique] / Kit K. ELAM, Auteur ; Laurie A. CHASSIN, Auteur ; Danielle PANDIKA, Auteur . - p.1715-1728. Langues : Anglais (eng) in Development and Psychopathology > 30-5 (December 2018) . - p.1715-1728 Index. décimale : PER Périodiques Résumé : Poor family cohesion and elevated adolescent aggression are associated with greater alcohol use in adolescence and early adulthood. In addition, evocative gene–environment correlations (rGEs) can underlie the interplay between offspring characteristics and negative family functioning, contributing to substance use. Gene–environment interplay has rarely been examined in racial/ethnic minority populations. The current study examined adolescents’ polygenic risk scores for aggression in evocative rGEs underlying aggression and family cohesion during adolescence, their contributions to alcohol use in early adulthood (n = 479), and differences between Mexican American and European American subsamples. Results suggest an evocative rGE between polygenic risk scores, aggression, and low family cohesion, with aggression contributing to low family cohesion over time. Greater family cohesion was associated with lower levels of alcohol use in early adulthood and this association was stronger for Mexican American adolescents compared to European American adolescents. Results are discussed with respect to integration of culture and racial/ethnic minority samples into genetic research and implications for alcohol use. En ligne : http://dx.doi.org/10.1017/S0954579418000901 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

Predicting substance use in emerging adulthood: A genetically informed study of developmental transactions between impulsivity and family conflict / Kit K. ELAM in Development and Psychopathology, 28-3 (August 2016)  

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Socialization processes within adolescents' relationships with parents and peers predicting couples' intimate partner violence in adulthood: A social learning perspective / Thao HA in Development and Psychopathology, 35-1 (February 2023)  

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