Autistic Children Quickly Orient Away from Both Eyes and Mouths During Face Observation / Lilja Kristin JONSDOTTIR in Journal of Autism and Developmental Disorders, 53-1 (January 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-1 (January 2023) . - p.495-502 Titre : Autistic Children Quickly Orient Away from Both Eyes and Mouths During Face Observation Type de document : texte imprimé Auteurs : Lilja Kristin JONSDOTTIR, Auteur ; Janina NEUFELD, Auteur ; Terje FALCK-YTTER, Auteur ; Johan LUNDIN KLEBERG, Auteur Article en page(s) : p.495-502 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Studies have supported two different hypotheses of reduced eye gaze in people with ASD; gaze avoidance and gaze indifference, while less is known about the role of anxiety. We tested these hypotheses using an eye-tracking paradigm that cued the eyes or mouth of emotional faces. Autistic children (n=12, mean age 7 years) looked faster away from both eyes and mouths than controls (n=22). This effect was not explained by anxiety symptoms. No difference was found in latency towards either area. These results indicate that attentional avoidance of autistic children is not specific to eyes, and that they do not show attentional indifference to eyes compared to controls. Atypicalities in visual scanning in ASD are possibly unrelated to specific facial areas. En ligne : https://doi.org/10.1007/s10803-021-05378-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493 [article] Autistic Children Quickly Orient Away from Both Eyes and Mouths During Face Observation [texte imprimé] / Lilja Kristin JONSDOTTIR, Auteur ; Janina NEUFELD, Auteur ; Terje FALCK-YTTER, Auteur ; Johan LUNDIN KLEBERG, Auteur . - p.495-502. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-1 (January 2023) . - p.495-502 Index. décimale : PER Périodiques Résumé : Studies have supported two different hypotheses of reduced eye gaze in people with ASD; gaze avoidance and gaze indifference, while less is known about the role of anxiety. We tested these hypotheses using an eye-tracking paradigm that cued the eyes or mouth of emotional faces. Autistic children (n=12, mean age 7 years) looked faster away from both eyes and mouths than controls (n=22). This effect was not explained by anxiety symptoms. No difference was found in latency towards either area. These results indicate that attentional avoidance of autistic children is not specific to eyes, and that they do not show attentional indifference to eyes compared to controls. Atypicalities in visual scanning in ASD are possibly unrelated to specific facial areas. En ligne : https://doi.org/10.1007/s10803-021-05378-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=493

A co-twin-control study of altered sensory processing in autism / Janina NEUFELD in Autism, 25-5 (July 2021)  

Public ISBD [article]  inAutism > 25-5 (July 2021) . - p.1422-1432 Titre : A co-twin-control study of altered sensory processing in autism Type de document : texte imprimé Auteurs : Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.1422-1432 Langues : Anglais (eng) Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] A co-twin-control study of altered sensory processing in autism [texte imprimé] / Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur . - p.1422-1432. Langues : Anglais (eng) in Autism > 25-5 (July 2021) . - p.1422-1432 Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

A co-twin-control study of altered sensory processing in autism / Janina NEUFELD in Autism, 26-5 (July 2022)  

Public ISBD [article]  inAutism > 26-5 (July 2022) . - p.1422-1432 Titre : A co-twin-control study of altered sensory processing in autism Type de document : texte imprimé Auteurs : Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.1422-1432 Langues : Anglais (eng) Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484 [article] A co-twin-control study of altered sensory processing in autism [texte imprimé] / Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur . - p.1422-1432. Langues : Anglais (eng) in Autism > 26-5 (July 2022) . - p.1422-1432 Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484

Eating Problems in Autistic Females and Males: A Co-twin Control Study / Karl LUNDIN REMNÉLIUS in Journal of Autism and Developmental Disorders, 52-7 (July 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.3153-3168 Titre : Eating Problems in Autistic Females and Males: A Co-twin Control Study Type de document : texte imprimé Auteurs : Karl LUNDIN REMNÉLIUS, Auteur ; Janina NEUFELD, Auteur ; Johan ISAKSSON, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.3153-3168 Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Autism Spectrum Disorder/genetics  Autistic Disorder/genetics  Diseases in Twins/genetics  Female  Humans  Male  Twins, Dizygotic  Twins, Monozygotic  Autism  Co-twin control design  Eating  Gender differences  lecturer for Medice and Roche. He receives royalties for textbooks and diagnostic  tools from Hogrefe. KLR, JN, and JI have no conflicts of interest to declare that  are relevant to the content of this article. Index. décimale : PER Périodiques Résumé : This study investigated the association between autism and self-reported eating problems and the influence of gender on the association, in a sample of adolescent and adult twins (N=192). Autistic traits and autism diagnosis were associated with both total and specific eating problems, including selective eating and sensory sensitivity during mealtimes. Interaction effects indicated a stronger association between autistic traits and total eating problems in females, as well as more difficulties with eating in social contexts among autistic females. In within-pair analyses, where unmeasured confounders including genes and shared environment are implicitly controlled for, the association was lost within monozygotic pairs, which might further indicate a genetic influence on the relationship between autism and eating problems. En ligne : http://dx.doi.org/10.1007/s10803-021-05198-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 [article] Eating Problems in Autistic Females and Males: A Co-twin Control Study [texte imprimé] / Karl LUNDIN REMNÉLIUS, Auteur ; Janina NEUFELD, Auteur ; Johan ISAKSSON, Auteur ; Sven BÖLTE, Auteur . - p.3153-3168. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.3153-3168 Mots-clés : Adolescent  Adult  Autism Spectrum Disorder/genetics  Autistic Disorder/genetics  Diseases in Twins/genetics  Female  Humans  Male  Twins, Dizygotic  Twins, Monozygotic  Autism  Co-twin control design  Eating  Gender differences  lecturer for Medice and Roche. He receives royalties for textbooks and diagnostic  tools from Hogrefe. KLR, JN, and JI have no conflicts of interest to declare that  are relevant to the content of this article. Index. décimale : PER Périodiques Résumé : This study investigated the association between autism and self-reported eating problems and the influence of gender on the association, in a sample of adolescent and adult twins (N=192). Autistic traits and autism diagnosis were associated with both total and specific eating problems, including selective eating and sensory sensitivity during mealtimes. Interaction effects indicated a stronger association between autistic traits and total eating problems in females, as well as more difficulties with eating in social contexts among autistic females. In within-pair analyses, where unmeasured confounders including genes and shared environment are implicitly controlled for, the association was lost within monozygotic pairs, which might further indicate a genetic influence on the relationship between autism and eating problems. En ligne : http://dx.doi.org/10.1007/s10803-021-05198-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477

EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort / Johan ISAKSSON in Molecular Autism, 9 (2018)  

Public ISBD [article]  inMolecular Autism > 9 (2018) . - 26p. Titre : EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort Type de document : texte imprimé Auteurs : Johan ISAKSSON, Auteur ; Kristiina TAMMIMIES, Auteur ; Janina NEUFELD, Auteur ; Elodie CAUVET, Auteur ; Karl LUNDIN, Auteur ; Jan K. BUITELAAR, Auteur ; Eva LOTH, Auteur ; Declan G.M. MURPHY, Auteur ; Will SPOOREN, Auteur ; Sven BÖLTE, Auteur Article en page(s) : 26p. Langues : Anglais (eng) Mots-clés : Adolescent  Autistic Disorder/diagnosis/epidemiology/genetics  Child  Cohort Studies  Europe  Female  Humans  Longitudinal Studies  Male  Phenotype  Twins, Dizygotic/statistics & numerical data  Twins, Monozygotic/statistics & numerical data  adhd  Autism spectrum disorder  Biomarkers  Brain  Cognition  Genetics  Intervention  Twins Index. décimale : PER Périodiques Résumé : EU-AIMS is the largest European research program aiming to identify stratification biomarkers and novel interventions for autism spectrum disorder (ASD). Within the program, the Longitudinal European Autism Project (LEAP) has recruited and comprehensively phenotyped a rare sample of 76 monozygotic and dizygotic twins, discordant, or concordant for ASD plus 30 typically developing twins. The aim of this letter is to complete previous descriptions of the LEAP case-control sample, clinically characterize, and investigate the suitability of the sample for ASD twin-control analyses purposes and share some 'lessons learnt.' Among the twins, a diagnosis of ASD is associated with increased symptom levels of ADHD, higher rates of intellectual disability, and lower family income. For the future, we conclude that the LEAP twin cohort offers multiple options for analyses of genetic and shared and non-shared environmental factors to generate new hypotheses for the larger cohort of LEAP singletons, but particularly cross-validate and refine evidence from it. En ligne : https://dx.doi.org/10.1186/s13229-018-0212-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort [texte imprimé] / Johan ISAKSSON, Auteur ; Kristiina TAMMIMIES, Auteur ; Janina NEUFELD, Auteur ; Elodie CAUVET, Auteur ; Karl LUNDIN, Auteur ; Jan K. BUITELAAR, Auteur ; Eva LOTH, Auteur ; Declan G.M. MURPHY, Auteur ; Will SPOOREN, Auteur ; Sven BÖLTE, Auteur . - 26p. Langues : Anglais (eng) in Molecular Autism > 9 (2018) . - 26p. Mots-clés : Adolescent  Autistic Disorder/diagnosis/epidemiology/genetics  Child  Cohort Studies  Europe  Female  Humans  Longitudinal Studies  Male  Phenotype  Twins, Dizygotic/statistics & numerical data  Twins, Monozygotic/statistics & numerical data  adhd  Autism spectrum disorder  Biomarkers  Brain  Cognition  Genetics  Intervention  Twins Index. décimale : PER Périodiques Résumé : EU-AIMS is the largest European research program aiming to identify stratification biomarkers and novel interventions for autism spectrum disorder (ASD). Within the program, the Longitudinal European Autism Project (LEAP) has recruited and comprehensively phenotyped a rare sample of 76 monozygotic and dizygotic twins, discordant, or concordant for ASD plus 30 typically developing twins. The aim of this letter is to complete previous descriptions of the LEAP case-control sample, clinically characterize, and investigate the suitability of the sample for ASD twin-control analyses purposes and share some 'lessons learnt.' Among the twins, a diagnosis of ASD is associated with increased symptom levels of ADHD, higher rates of intellectual disability, and lower family income. For the future, we conclude that the LEAP twin cohort offers multiple options for analyses of genetic and shared and non-shared environmental factors to generate new hypotheses for the larger cohort of LEAP singletons, but particularly cross-validate and refine evidence from it. En ligne : https://dx.doi.org/10.1186/s13229-018-0212-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

Familial confounding on the ability to read minds: A co-twin control study / Johan ISAKSSON in Autism, 23-8 (November 2019)  

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Global and local visual processing in autism - a co-twin-control study / Janina NEUFELD in Journal of Child Psychology and Psychiatry, 61-4 (April 2020)  

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Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism / Annelies VAN'T WESTEINDE in Molecular Autism, 11 (2020)  

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Social Cognition in Autism and Other Neurodevelopmental Disorders: A Co-twin Control Study / Johan ISAKSSON in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

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Spontaneous Facial Mimicry is Modulated by Joint Attention and Autistic Traits / Janina NEUFELD in Autism Research, 9-7 (July 2016)  

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The impact of atypical sensory processing on adaptive functioning within and beyond autism: The role of familial factors / Janina NEUFELD in Autism, 25-8 (November 2021)  

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