Structure of psychopathology in adolescents and its association with high-risk personality traits / Samantha J. LYNCH in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.379-394 Titre : Structure of psychopathology in adolescents and its association with high-risk personality traits Type de document : Texte imprimé et/ou numérique Auteurs : Samantha J. LYNCH, Auteur ; Matthew SUNDERLAND, Auteur ; Miriam K. FORBES, Auteur ; Maree TEESSON, Auteur ; Nicola C. NEWTON, Auteur ; Cath CHAPMAN, Auteur Article en page(s) : p.379-394 Langues : Anglais (eng) Mots-clés : adolescents  higher-order model  personality  psychopathology Index. décimale : PER Périodiques Résumé : The present study examined high-risk personality traits and associations with psychopathology across multiple levels of a hierarchical-dimensional model of psychopathology in a large adolescent, general population sample. Confirmatory factor analyses were run using data from two randomized controlled trials of Australian adolescents (N = 8,654, mean age = 13.01 years, 52% female). A higher-order model - comprised of general psychopathology, fear, distress, alcohol use/harms, and conduct/inattention dimensions - was selected based on model fit, reliability, and replicability. Indirect-effects models were estimated to examine the unique associations between high-risk personality traits (anxiety sensitivity, negative thinking, impulsivity, and sensation seeking) and general and specific dimensions and symptoms of psychopathology. All personality traits were positively associated with general psychopathology. After accounting for general psychopathology, anxiety sensitivity was positively associated with fear; negative thinking was positively associated with distress; impulsivity was positively associated with conduct/inattention; and sensation seeking was positively associated with alcohol use/harms and conduct/inattention, and negatively associated with fear. Several significant associations between personality traits and individual symptoms remained after accounting for general and specific psychopathology. These findings contribute to our understanding of the underlying structure of psychopathology among adolescents and have implications for the development of personality-based prevention and early intervention programs. En ligne : https://dx.doi.org/10.1017/S0954579422001262 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Structure of psychopathology in adolescents and its association with high-risk personality traits [Texte imprimé et/ou numérique] / Samantha J. LYNCH, Auteur ; Matthew SUNDERLAND, Auteur ; Miriam K. FORBES, Auteur ; Maree TEESSON, Auteur ; Nicola C. NEWTON, Auteur ; Cath CHAPMAN, Auteur . - p.379-394. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.379-394 Mots-clés : adolescents  higher-order model  personality  psychopathology Index. décimale : PER Périodiques Résumé : The present study examined high-risk personality traits and associations with psychopathology across multiple levels of a hierarchical-dimensional model of psychopathology in a large adolescent, general population sample. Confirmatory factor analyses were run using data from two randomized controlled trials of Australian adolescents (N = 8,654, mean age = 13.01 years, 52% female). A higher-order model - comprised of general psychopathology, fear, distress, alcohol use/harms, and conduct/inattention dimensions - was selected based on model fit, reliability, and replicability. Indirect-effects models were estimated to examine the unique associations between high-risk personality traits (anxiety sensitivity, negative thinking, impulsivity, and sensation seeking) and general and specific dimensions and symptoms of psychopathology. All personality traits were positively associated with general psychopathology. After accounting for general psychopathology, anxiety sensitivity was positively associated with fear; negative thinking was positively associated with distress; impulsivity was positively associated with conduct/inattention; and sensation seeking was positively associated with alcohol use/harms and conduct/inattention, and negatively associated with fear. Several significant associations between personality traits and individual symptoms remained after accounting for general and specific psychopathology. These findings contribute to our understanding of the underlying structure of psychopathology among adolescents and have implications for the development of personality-based prevention and early intervention programs. En ligne : https://dx.doi.org/10.1017/S0954579422001262 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

The long-term effectiveness of a selective, personality-targeted prevention program in reducing alcohol use and related harms: a cluster randomized controlled trial / Nicola C. NEWTON in Journal of Child Psychology and Psychiatry, 57-9 (September 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-9 (September 2016) . - p.1056-1065 Titre : The long-term effectiveness of a selective, personality-targeted prevention program in reducing alcohol use and related harms: a cluster randomized controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Nicola C. NEWTON, Auteur ; Patricia J. CONROD, Auteur ; Tim SLADE, Auteur ; Natacha CARRAGHER, Auteur ; Katrina E. CHAMPION, Auteur ; Emma L. BARRETT, Auteur ; Erin V. KELLY, Auteur ; Natasha K. NAIR, Auteur ; Lexine STAPINSKI, Auteur ; Maree TEESSON, Auteur Article en page(s) : p.1056-1065 Langues : Anglais (eng) Mots-clés : Prevention  personality  alcohol abuse  adolescence  school Index. décimale : PER Périodiques Résumé : Background This study investigated the long-term effectiveness of Preventure, a selective personality-targeted prevention program, in reducing the uptake of alcohol, harmful use of alcohol, and alcohol-related harms over a 3-year period. Methods A cluster randomized controlled trial was conducted to assess the effectiveness of Preventure. Schools were block randomized to one of two groups: the Preventure group (n = 7 schools) and the Control group (n = 7 schools). Only students screening as high-risk on one of four personality profiles (anxiety sensitivity, negative thinking, impulsivity, and sensation seeking) were included in the analysis. All students were assessed at five time points over a 3-year period: baseline; immediately after the intervention; and 12, 24, and 36 months after baseline. Students were assessed on frequency of drinking, binge drinking, and alcohol-related harms. Two-part latent growth models were used to analyze intervention effects, which included all students with data available at each time point. This trial is registered with the Australian New Zealand Clinical Trials Registry (ACTRN12612000026820; www.anzctr.org.au). Results A total of 438 high-risk adolescents (mean age, 13.4 years; SD = 0.47) from 14 Australian schools were recruited to the study and completed baseline assessments. Relative to high-risk Control students, high-risk Preventure students displayed significantly reduced growth in their likelihood to consume alcohol [b = ?0.225 (0.061); p < .001], to binge drink [b = ?0.305 (.096); p = 0.001], and to experience alcohol-related harms [b = ?0.255 (0.096); p = .008] over 36 months. Conclusions Findings from this study support the use of selective personality-targeted preventive interventions in reducing the uptake of alcohol, alcohol misuse, and related harms over the long term. This trial is the first to demonstrate the effects of a selective alcohol prevention program over a 3-year period and the first to demonstrate the effects of a selective preventive intervention in Australia. En ligne : http://dx.doi.org/10.1111/jcpp.12558 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292 [article] The long-term effectiveness of a selective, personality-targeted prevention program in reducing alcohol use and related harms: a cluster randomized controlled trial [Texte imprimé et/ou numérique] / Nicola C. NEWTON, Auteur ; Patricia J. CONROD, Auteur ; Tim SLADE, Auteur ; Natacha CARRAGHER, Auteur ; Katrina E. CHAMPION, Auteur ; Emma L. BARRETT, Auteur ; Erin V. KELLY, Auteur ; Natasha K. NAIR, Auteur ; Lexine STAPINSKI, Auteur ; Maree TEESSON, Auteur . - p.1056-1065. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-9 (September 2016) . - p.1056-1065 Mots-clés : Prevention  personality  alcohol abuse  adolescence  school Index. décimale : PER Périodiques Résumé : Background This study investigated the long-term effectiveness of Preventure, a selective personality-targeted prevention program, in reducing the uptake of alcohol, harmful use of alcohol, and alcohol-related harms over a 3-year period. Methods A cluster randomized controlled trial was conducted to assess the effectiveness of Preventure. Schools were block randomized to one of two groups: the Preventure group (n = 7 schools) and the Control group (n = 7 schools). Only students screening as high-risk on one of four personality profiles (anxiety sensitivity, negative thinking, impulsivity, and sensation seeking) were included in the analysis. All students were assessed at five time points over a 3-year period: baseline; immediately after the intervention; and 12, 24, and 36 months after baseline. Students were assessed on frequency of drinking, binge drinking, and alcohol-related harms. Two-part latent growth models were used to analyze intervention effects, which included all students with data available at each time point. This trial is registered with the Australian New Zealand Clinical Trials Registry (ACTRN12612000026820; www.anzctr.org.au). Results A total of 438 high-risk adolescents (mean age, 13.4 years; SD = 0.47) from 14 Australian schools were recruited to the study and completed baseline assessments. Relative to high-risk Control students, high-risk Preventure students displayed significantly reduced growth in their likelihood to consume alcohol [b = ?0.225 (0.061); p < .001], to binge drink [b = ?0.305 (.096); p = 0.001], and to experience alcohol-related harms [b = ?0.255 (0.096); p = .008] over 36 months. Conclusions Findings from this study support the use of selective personality-targeted preventive interventions in reducing the uptake of alcohol, alcohol misuse, and related harms over the long term. This trial is the first to demonstrate the effects of a selective alcohol prevention program over a 3-year period and the first to demonstrate the effects of a selective preventive intervention in Australia. En ligne : http://dx.doi.org/10.1111/jcpp.12558 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292

The relationship between brain structure and general psychopathology in preadolescents / Louise MEWTON in Journal of Child Psychology and Psychiatry, 63-7 (July 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.734-744 Titre : The relationship between brain structure and general psychopathology in preadolescents Type de document : Texte imprimé et/ou numérique Auteurs : Louise MEWTON, Auteur ; Briana LEES, Auteur ; Lindsay M. SQUEGLIA, Auteur ; Miriam K. FORBES, Auteur ; Matthew SUNDERLAND, Auteur ; Robert F. KRUEGER, Auteur ; Forrest C. KOCH, Auteur ; Andrew BAILLIE, Auteur ; Tim SLADE, Auteur ; Nicholas HOY, Auteur ; Maree TEESSON, Auteur Article en page(s) : p.734-744 Langues : Anglais (eng) Mots-clés : Adolescent  Bayes Theorem  Brain  Child  Cognition  Humans  Male  Mental Disorders/psychology  Psychopathology  Generalized psychopathology  brain structure  externalizing  internalizing  preadolescence  interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: An emerging body of literature has indicated that broad, transdiagnostic dimensions of psychopathology are associated with alterations in brain structure across the life span. The current study aimed to investigate the relationship between brain structure and broad dimensions of psychopathology in the critical preadolescent period when psychopathology is emerging. METHODS: This study included baseline data from the Adolescent Brain and Cognitive Development (ABCD) Study(®) (n=11,875; age range=9-10?years; male=52.2%). General psychopathology, externalizing, internalizing, and thought disorder dimensions were based on a higher-order model of psychopathology and estimated using Bayesian plausible values. Outcome variables included global and regional cortical volume, thickness, and surface area. RESULTS: Higher levels of psychopathology across all dimensions were associated with lower volume and surface area globally, as well as widespread and pervasive alterations across the majority of cortical and subcortical regions studied, after adjusting for sex, race/ethnicity, parental education, income, and maternal psychopathology. The relationships between general psychopathology and brain structure were attenuated when adjusting for cognitive functioning. There were no statistically significant relationships between psychopathology and cortical thickness in this sample of preadolescents. CONCLUSIONS: The current study identified lower cortical volume and surface area as transdiagnostic biomarkers for general psychopathology in preadolescence. Future research may focus on whether the widespread and pervasive relationships between general psychopathology and brain structure reflect cognitive dysfunction that is a feature across a range of mental illnesses. En ligne : http://dx.doi.org/10.1111/jcpp.13513 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 [article] The relationship between brain structure and general psychopathology in preadolescents [Texte imprimé et/ou numérique] / Louise MEWTON, Auteur ; Briana LEES, Auteur ; Lindsay M. SQUEGLIA, Auteur ; Miriam K. FORBES, Auteur ; Matthew SUNDERLAND, Auteur ; Robert F. KRUEGER, Auteur ; Forrest C. KOCH, Auteur ; Andrew BAILLIE, Auteur ; Tim SLADE, Auteur ; Nicholas HOY, Auteur ; Maree TEESSON, Auteur . - p.734-744. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.734-744 Mots-clés : Adolescent  Bayes Theorem  Brain  Child  Cognition  Humans  Male  Mental Disorders/psychology  Psychopathology  Generalized psychopathology  brain structure  externalizing  internalizing  preadolescence  interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: An emerging body of literature has indicated that broad, transdiagnostic dimensions of psychopathology are associated with alterations in brain structure across the life span. The current study aimed to investigate the relationship between brain structure and broad dimensions of psychopathology in the critical preadolescent period when psychopathology is emerging. METHODS: This study included baseline data from the Adolescent Brain and Cognitive Development (ABCD) Study(®) (n=11,875; age range=9-10?years; male=52.2%). General psychopathology, externalizing, internalizing, and thought disorder dimensions were based on a higher-order model of psychopathology and estimated using Bayesian plausible values. Outcome variables included global and regional cortical volume, thickness, and surface area. RESULTS: Higher levels of psychopathology across all dimensions were associated with lower volume and surface area globally, as well as widespread and pervasive alterations across the majority of cortical and subcortical regions studied, after adjusting for sex, race/ethnicity, parental education, income, and maternal psychopathology. The relationships between general psychopathology and brain structure were attenuated when adjusting for cognitive functioning. There were no statistically significant relationships between psychopathology and cortical thickness in this sample of preadolescents. CONCLUSIONS: The current study identified lower cortical volume and surface area as transdiagnostic biomarkers for general psychopathology in preadolescence. Future research may focus on whether the widespread and pervasive relationships between general psychopathology and brain structure reflect cognitive dysfunction that is a feature across a range of mental illnesses. En ligne : http://dx.doi.org/10.1111/jcpp.13513 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477

The structure of psychopathology and association with poor sleep, self-harm, suicidality, risky sexual behavior, and low self-esteem in a population sample of adolescents / Matthew SUNDERLAND in Development and Psychopathology, 33-4 (October 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-4 (October 2021) . - p.1208-1219 Titre : The structure of psychopathology and association with poor sleep, self-harm, suicidality, risky sexual behavior, and low self-esteem in a population sample of adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Matthew SUNDERLAND, Auteur ; Miriam K. FORBES, Auteur ; Louise MEWTON, Auteur ; Andrew BAILLIE, Auteur ; Natacha CARRAGHER, Auteur ; Samantha J. LYNCH, Auteur ; Philip J. BATTERHAM, Auteur ; Alison L. CALEAR, Auteur ; Cath CHAPMAN, Auteur ; Nicola C. NEWTON, Auteur ; Maree TEESSON, Auteur ; Tim SLADE, Auteur Article en page(s) : p.1208-1219 Langues : Anglais (eng) Mots-clés : adolescents  confirmatory factor analysis  psychopathology  validity Index. décimale : PER Périodiques Résumé : There is a growing body of evidence highlighting the presence of a single general dimension of psychopathology that can account for multiple associations across mental and substance use disorders. However, relatively little evidence has emerged regarding the validity of this model with respect to a range of factors that have been previously implicated across multiple disorders. The current study utilized a cross-sectional population survey of adolescents (n = 2,003) to examine the extent to which broad psychopathology factors account for specific associations between psychopathology and key validators: poor sleep, self-harm, suicidality, risky sexual behavior, and low self-esteem. Confirmatory factor models, latent class models, and factor mixture models were estimated to identify the best structure of psychopathology. Structural equation models were then estimated to examine the broad and specific associations between each psychopathology indicator and the validators. A confirmatory factor model with three lower-order factors, representing internalizing, externalizing, and psychotic-like experiences, and a single higher-order factor evidenced the best fit. The associations between manifest indicators of psychopathology and validators were largely nonspecific. However, significant and large direct effects were found between several pairwise associations. These findings have implications for the identification of potential targets for intervention and/or tailoring of prevention programs. En ligne : http://dx.doi.org/10.1017/S0954579420000437 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] The structure of psychopathology and association with poor sleep, self-harm, suicidality, risky sexual behavior, and low self-esteem in a population sample of adolescents [Texte imprimé et/ou numérique] / Matthew SUNDERLAND, Auteur ; Miriam K. FORBES, Auteur ; Louise MEWTON, Auteur ; Andrew BAILLIE, Auteur ; Natacha CARRAGHER, Auteur ; Samantha J. LYNCH, Auteur ; Philip J. BATTERHAM, Auteur ; Alison L. CALEAR, Auteur ; Cath CHAPMAN, Auteur ; Nicola C. NEWTON, Auteur ; Maree TEESSON, Auteur ; Tim SLADE, Auteur . - p.1208-1219. Langues : Anglais (eng) in Development and Psychopathology > 33-4 (October 2021) . - p.1208-1219 Mots-clés : adolescents  confirmatory factor analysis  psychopathology  validity Index. décimale : PER Périodiques Résumé : There is a growing body of evidence highlighting the presence of a single general dimension of psychopathology that can account for multiple associations across mental and substance use disorders. However, relatively little evidence has emerged regarding the validity of this model with respect to a range of factors that have been previously implicated across multiple disorders. The current study utilized a cross-sectional population survey of adolescents (n = 2,003) to examine the extent to which broad psychopathology factors account for specific associations between psychopathology and key validators: poor sleep, self-harm, suicidality, risky sexual behavior, and low self-esteem. Confirmatory factor models, latent class models, and factor mixture models were estimated to identify the best structure of psychopathology. Structural equation models were then estimated to examine the broad and specific associations between each psychopathology indicator and the validators. A confirmatory factor model with three lower-order factors, representing internalizing, externalizing, and psychotic-like experiences, and a single higher-order factor evidenced the best fit. The associations between manifest indicators of psychopathology and validators were largely nonspecific. However, significant and large direct effects were found between several pairwise associations. These findings have implications for the identification of potential targets for intervention and/or tailoring of prevention programs. En ligne : http://dx.doi.org/10.1017/S0954579420000437 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

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