Autism spectrum disorder: An examination of sex differences in neuropsychological and self-report measures of executive and non-executive cognitive function / Eleni A. DEMETRIOU in Autism, 25-8 (November 2021)  

Public ISBD [article]  inAutism > 25-8 (November 2021) . - p.2223-2237 Titre : Autism spectrum disorder: An examination of sex differences in neuropsychological and self-report measures of executive and non-executive cognitive function Type de document : Texte imprimé et/ou numérique Auteurs : Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; S. H. PARK, Auteur ; L. PELLICANO, Auteur ; Y. J. C. SONG, Auteur ; S. L. NAISMITH, Auteur ; I. B. HICKIE, Auteur ; E. E. THOMAS, Auteur ; A. J. GUASTELLA, Auteur Article en page(s) : p.2223-2237 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Cognition  Executive Function  Female  Humans  Male  Neuropsychological Tests  Self Report  Sex Characteristics  Behavioural Rating Inventory of Executive Function  Cambridge Neuropsychological Test Automated Battery  autism spectrum disorder  executive function  sex differences Index. décimale : PER Périodiques Résumé : Research comparing females and males with a diagnosis of autism suggests that there are sex differences in some characteristics such as behaviour regulation. One area not studied in detail is whether females and males with autism perform differently in tests of cognitive ability. The results of previous research are quite mixed. One explanation may be that some research comparing females and males with autism did not include a neurotypical control group for comparison. As a result, it is not clear whether the sex differences in cognitive ability observed in people with autism are similar to differences between neurotypical males and females. To better understand whether there are unique differences between males and females with autism, it is important to also compare them with neurotypical males and females. In our research, we included a neurotypical group and compared males and females with and without a diagnosis of autism. We found that the sex differences in autism are similar to what we observe in males and females without autism. Our study showed that compared with males, females (with and without autism) do better in assessments of processing speed, cognitive flexibility, verbal learning and memory and semantic fluency. Our results suggest that although females show different cognitive performance to males, these sex differences were not specific to the group with a diagnosis of autism. En ligne : http://dx.doi.org/10.1177/13623613211014991 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Autism spectrum disorder: An examination of sex differences in neuropsychological and self-report measures of executive and non-executive cognitive function [Texte imprimé et/ou numérique] / Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; S. H. PARK, Auteur ; L. PELLICANO, Auteur ; Y. J. C. SONG, Auteur ; S. L. NAISMITH, Auteur ; I. B. HICKIE, Auteur ; E. E. THOMAS, Auteur ; A. J. GUASTELLA, Auteur . - p.2223-2237. Langues : Anglais (eng) in Autism > 25-8 (November 2021) . - p.2223-2237 Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Cognition  Executive Function  Female  Humans  Male  Neuropsychological Tests  Self Report  Sex Characteristics  Behavioural Rating Inventory of Executive Function  Cambridge Neuropsychological Test Automated Battery  autism spectrum disorder  executive function  sex differences Index. décimale : PER Périodiques Résumé : Research comparing females and males with a diagnosis of autism suggests that there are sex differences in some characteristics such as behaviour regulation. One area not studied in detail is whether females and males with autism perform differently in tests of cognitive ability. The results of previous research are quite mixed. One explanation may be that some research comparing females and males with autism did not include a neurotypical control group for comparison. As a result, it is not clear whether the sex differences in cognitive ability observed in people with autism are similar to differences between neurotypical males and females. To better understand whether there are unique differences between males and females with autism, it is important to also compare them with neurotypical males and females. In our research, we included a neurotypical group and compared males and females with and without a diagnosis of autism. We found that the sex differences in autism are similar to what we observe in males and females without autism. Our study showed that compared with males, females (with and without autism) do better in assessments of processing speed, cognitive flexibility, verbal learning and memory and semantic fluency. Our results suggest that although females show different cognitive performance to males, these sex differences were not specific to the group with a diagnosis of autism. En ligne : http://dx.doi.org/10.1177/13623613211014991 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Disability, functioning, and quality of life among treatment-seeking young autistic adults and its relation to depression, anxiety, and stress / S. H. PARK in Autism, 23-7 (October 2019)  

Public ISBD [article]  inAutism > 23-7 (October 2019) . - p.1675-1686 Titre : Disability, functioning, and quality of life among treatment-seeking young autistic adults and its relation to depression, anxiety, and stress Type de document : Texte imprimé et/ou numérique Auteurs : S. H. PARK, Auteur ; Y. J. C. SONG, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; A. NORTON, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; D. F. HERMENS, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur Article en page(s) : p.1675-1686 Langues : Anglais (eng) Mots-clés : developmental disorders  distress  health services  mental health  treatment  well being Index. décimale : PER Périodiques Résumé : In this study, we consecutively recruited treatment-seeking young autistic adults without intellectual impairment aged 16-30 years who presented to a mental health service and evaluated general health (distress, quality of life, and disability), functioning (work loss days and social functioning), and mood symptoms (depression, anxiety, and stress) in those diagnosed with autism spectrum disorder (n = 96). This group was compared to young adults presenting to the same service with primary mental health disorders (depression, n = 343; bipolar, n = 132; psychosis, n = 166; and anxiety, n = 303). This study also investigated the influence of mood symptoms on general health and functioning in the autism spectrum disorder group. Young autistic adults reported significant general health and functioning impairments that were of similar degree to those presenting with primary mental health disorders. Interestingly, the autistic group also reported similarly high levels of mood symptoms to those with primary depressive and anxiety disorders. In the autistic group, depressive symptoms were strongly associated with distress, quality of life, and work loss days, while stress symptoms were strongly associated with disability. This study highlights further research, and mental health services are required specifically targeting young autistic adults to address their significant unmet needs. En ligne : http://dx.doi.org/10.1177/1362361318823925 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406 [article] Disability, functioning, and quality of life among treatment-seeking young autistic adults and its relation to depression, anxiety, and stress [Texte imprimé et/ou numérique] / S. H. PARK, Auteur ; Y. J. C. SONG, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; A. NORTON, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; D. F. HERMENS, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur . - p.1675-1686. Langues : Anglais (eng) in Autism > 23-7 (October 2019) . - p.1675-1686 Mots-clés : developmental disorders  distress  health services  mental health  treatment  well being Index. décimale : PER Périodiques Résumé : In this study, we consecutively recruited treatment-seeking young autistic adults without intellectual impairment aged 16-30 years who presented to a mental health service and evaluated general health (distress, quality of life, and disability), functioning (work loss days and social functioning), and mood symptoms (depression, anxiety, and stress) in those diagnosed with autism spectrum disorder (n = 96). This group was compared to young adults presenting to the same service with primary mental health disorders (depression, n = 343; bipolar, n = 132; psychosis, n = 166; and anxiety, n = 303). This study also investigated the influence of mood symptoms on general health and functioning in the autism spectrum disorder group. Young autistic adults reported significant general health and functioning impairments that were of similar degree to those presenting with primary mental health disorders. Interestingly, the autistic group also reported similarly high levels of mood symptoms to those with primary depressive and anxiety disorders. In the autistic group, depressive symptoms were strongly associated with distress, quality of life, and work loss days, while stress symptoms were strongly associated with disability. This study highlights further research, and mental health services are required specifically targeting young autistic adults to address their significant unmet needs. En ligne : http://dx.doi.org/10.1177/1362361318823925 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406

Evidence of a reduced role for circumscribed interests in the social attention patterns of children with Autism Spectrum Disorder / Z. AMBARCHI in Journal of Autism and Developmental Disorders, 53-10 (October 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-10 (October 2023) . - p.3999-4011 Titre : Evidence of a reduced role for circumscribed interests in the social attention patterns of children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Z. AMBARCHI, Auteur ; K. A. BOULTON, Auteur ; R. THAPA, Auteur ; E. E. THOMAS, Auteur ; M. M. DEMAYO, Auteur ; N. J. SASSON, Auteur ; I. B. HICKIE, Auteur ; Adam J. GUASTELLA, Auteur Article en page(s) : p.3999-4011 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Reduced social attention is characteristic of Autism Spectrum Disorder (ASD). It has been suggested to result from an early onset and excessive influence of circumscribed interests (CIs) on gaze behaviour, compared to typically developing (TYP) individuals. To date, these findings have been mixed. The current eye-tracking study utilised a visual preference paradigm to investigate the influence of CI versus non-CI objects on attention patterns in children with ASD (aged 3-12 years, n=37) and their age-matched TYP peers (n=30). Compared to TYP, social and object attention was reduced in the ASD group irrespective of the presence of CIs. Results suggest a reduced role for CIs and extend recent evidence of atypical attention patterns across social and non-social domains in ASD. En ligne : https://doi.org/10.1007/s10803-022-05638-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] Evidence of a reduced role for circumscribed interests in the social attention patterns of children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Z. AMBARCHI, Auteur ; K. A. BOULTON, Auteur ; R. THAPA, Auteur ; E. E. THOMAS, Auteur ; M. M. DEMAYO, Auteur ; N. J. SASSON, Auteur ; I. B. HICKIE, Auteur ; Adam J. GUASTELLA, Auteur . - p.3999-4011. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-10 (October 2023) . - p.3999-4011 Index. décimale : PER Périodiques Résumé : Reduced social attention is characteristic of Autism Spectrum Disorder (ASD). It has been suggested to result from an early onset and excessive influence of circumscribed interests (CIs) on gaze behaviour, compared to typically developing (TYP) individuals. To date, these findings have been mixed. The current eye-tracking study utilised a visual preference paradigm to investigate the influence of CI versus non-CI objects on attention patterns in children with ASD (aged 3-12 years, n=37) and their age-matched TYP peers (n=30). Compared to TYP, social and object attention was reduced in the ASD group irrespective of the presence of CIs. Results suggest a reduced role for CIs and extend recent evidence of atypical attention patterns across social and non-social domains in ASD. En ligne : https://doi.org/10.1007/s10803-022-05638-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

Reduced heart rate variability in adults with autism spectrum disorder / R. THAPA in Autism Research, 12-6 (June 2019)  

Public ISBD [article]  inAutism Research > 12-6 (June 2019) . - p.922-930 Titre : Reduced heart rate variability in adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : R. THAPA, Auteur ; Gail A. ALVARES, Auteur ; T. A. ZAIDI, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; S. H. PARK, Auteur ; A. J. GUASTELLA, Auteur Année de publication : 2019 Article en page(s) : p.922-930 Langues : Anglais (eng) Mots-clés : autonomic nervous system  biological marker  heart rate variability  mental health  parasympathetic nervous system  social development  sympathetic nervous system Index. décimale : PER Périodiques Résumé : A growing body of research has suggested heart rate variability (HRV) may be reduced in autism spectrum disorder (ASD) in comparison to neurotypical cohorts. While there have been several studies investigating HRV in children diagnosed with ASD, few studies have been conducted in adults. The objective of the current study was to investigate autonomic nervous system activity as assessed by HRV in adults diagnosed with ASD. We hypothesized that adults with ASD would show a reduction in HRV compared to neurotypical participants. Participants diagnosed with ASD (n = 55) were recruited from the Autism Clinic for Translational Research at the Brain and Mind Centre (University of Sydney) between 2013 and 2017. Neurotypical participants were recruited from advertisements and online media. Resting state heart rate was measured for 5 min while participants sat in an upright position. Results showed there was an overall significant difference in resting-state HRV between adults diagnosed with ASD compared to the neurotypical control group. Logarithmically transformed high frequency (HF) and root mean square of successive differences were particularly decreased in the ASD group, suggesting lower parasympathetic activity. The use of psychotropic medications and comorbidities were associated with reductions in low frequency of HRV. Our data suggest an overall dysregulation in resting autonomic activity in adults with ASD. This may represent an important physiological mechanism leading to potential cardiovascular risk in ASD, which warrants further investigation. Autism Res 2019, 12: 922-930. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: ASD is commonly associated with a range of physical and mental health comorbidities. Autonomic disruptions underlying reductions in heart rate variability (HRV) have been linked to a range of mental and physical health conditions. We assessed resting-state HRV in adults diagnosed with ASD in comparison to healthy individuals. Our results showed reduced heart rate variability in people diagnosed with ASD compared to adults without ASD. These findings implicate a role for autonomic activity as a potentially modifiable risk factor for ASD. En ligne : https://dx.doi.org/10.1002/aur.2104 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400 [article] Reduced heart rate variability in adults with autism spectrum disorder [Texte imprimé et/ou numérique] / R. THAPA, Auteur ; Gail A. ALVARES, Auteur ; T. A. ZAIDI, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; S. H. PARK, Auteur ; A. J. GUASTELLA, Auteur . - 2019 . - p.922-930. Langues : Anglais (eng) in Autism Research > 12-6 (June 2019) . - p.922-930 Mots-clés : autonomic nervous system  biological marker  heart rate variability  mental health  parasympathetic nervous system  social development  sympathetic nervous system Index. décimale : PER Périodiques Résumé : A growing body of research has suggested heart rate variability (HRV) may be reduced in autism spectrum disorder (ASD) in comparison to neurotypical cohorts. While there have been several studies investigating HRV in children diagnosed with ASD, few studies have been conducted in adults. The objective of the current study was to investigate autonomic nervous system activity as assessed by HRV in adults diagnosed with ASD. We hypothesized that adults with ASD would show a reduction in HRV compared to neurotypical participants. Participants diagnosed with ASD (n = 55) were recruited from the Autism Clinic for Translational Research at the Brain and Mind Centre (University of Sydney) between 2013 and 2017. Neurotypical participants were recruited from advertisements and online media. Resting state heart rate was measured for 5 min while participants sat in an upright position. Results showed there was an overall significant difference in resting-state HRV between adults diagnosed with ASD compared to the neurotypical control group. Logarithmically transformed high frequency (HF) and root mean square of successive differences were particularly decreased in the ASD group, suggesting lower parasympathetic activity. The use of psychotropic medications and comorbidities were associated with reductions in low frequency of HRV. Our data suggest an overall dysregulation in resting autonomic activity in adults with ASD. This may represent an important physiological mechanism leading to potential cardiovascular risk in ASD, which warrants further investigation. Autism Res 2019, 12: 922-930. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: ASD is commonly associated with a range of physical and mental health comorbidities. Autonomic disruptions underlying reductions in heart rate variability (HRV) have been linked to a range of mental and physical health conditions. We assessed resting-state HRV in adults diagnosed with ASD in comparison to healthy individuals. Our results showed reduced heart rate variability in people diagnosed with ASD compared to adults without ASD. These findings implicate a role for autonomic activity as a potentially modifiable risk factor for ASD. En ligne : https://dx.doi.org/10.1002/aur.2104 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400

Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder / S. H. PARK in Autism Research, 12-12 (December)  

Public ISBD [article]  inAutism Research > 12-12 (December) . - p.1726-1727 Titre : Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur Année de publication : 2019 Article en page(s) : p.1726-1727 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 [article] Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder [Texte imprimé et/ou numérique] / S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur . - 2019 . - p.1726-1727. Langues : Anglais (eng) in Autism Research > 12-12 (December) . - p.1726-1727 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413

The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder / Marilena M. DEMAYO in Journal of Autism and Developmental Disorders, 52-3 (March 2022)  

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Validation of the 36-item and 12-item self-report World Health Organization Disability Assessment Schedule II (WHODAS-II) in individuals with autism spectrum disorder / S. H. PARK in Autism Research, 12-7 (July 2019)  

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