Development of ADHD symptoms in preschool children: Genetic and environmental contributions / E. M. EILERTSEN in Development and Psychopathology, 31-4 (October 2019)  

Public ISBD [article]  inDevelopment and Psychopathology > 31-4 (October 2019) . - p.1299-1305 Titre : Development of ADHD symptoms in preschool children: Genetic and environmental contributions Type de document : Texte imprimé et/ou numérique Auteurs : E. M. EILERTSEN, Auteur ; L. C. GJERDE, Auteur ; Kenneth S. KENDLER, Auteur ; E. ROYSAMB, Auteur ; S. H. AGGEN, Auteur ; K. GUSTAVSON, Auteur ; T. REICHBORN-KJENNERUD, Auteur ; E. YSTROM, Auteur Article en page(s) : p.1299-1305 Langues : Anglais (eng) Mots-clés : Norwegian Mother and Child Cohort Study (MoBa)  attention-deficit/hyperactivity disorder symptoms  heritability  longitudinal  twin study Index. décimale : PER Périodiques Résumé : We examined genetic and environmental contributions to the development of symptoms of attention-deficit/hyperactivity disorder (ADHD) in preschool children. ADHD symptoms in siblings at 1.5, 3, and 5 years of age were investigated in a population-based sample from the prospective Norwegian Mother and Child Cohort Study. The longitudinal contributions of additive genetic, shared, twin-specific, and unique environmental influences were estimated using biometric structural equation models. Heritability of ADHD symptoms ranged from 54% to 70%. There was evidence of partially new genetic influences at successive ages, with genetic correlations ranging from .58 to .89. Contributions from shared environmental factors and twin-specific factors were minor. The importance of unique environmental effects appeared to increase across ages, and was mostly specific to a given age. There was no evidence suggesting that this pattern differs across males and females. Symptoms of ADHD are highly heritability in young children from as early as 1.5 years of age. Longitudinal stability of ADHD symptoms is mainly attributable to genetic influences, but there is also some evidence for age-specific genetic influences. These findings contribute to our understanding of development of ADHD early in life, and can guide future molecular genetics studies. En ligne : http://dx.doi.org/10.1017/s0954579418000731 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406 [article] Development of ADHD symptoms in preschool children: Genetic and environmental contributions [Texte imprimé et/ou numérique] / E. M. EILERTSEN, Auteur ; L. C. GJERDE, Auteur ; Kenneth S. KENDLER, Auteur ; E. ROYSAMB, Auteur ; S. H. AGGEN, Auteur ; K. GUSTAVSON, Auteur ; T. REICHBORN-KJENNERUD, Auteur ; E. YSTROM, Auteur . - p.1299-1305. Langues : Anglais (eng) in Development and Psychopathology > 31-4 (October 2019) . - p.1299-1305 Mots-clés : Norwegian Mother and Child Cohort Study (MoBa)  attention-deficit/hyperactivity disorder symptoms  heritability  longitudinal  twin study Index. décimale : PER Périodiques Résumé : We examined genetic and environmental contributions to the development of symptoms of attention-deficit/hyperactivity disorder (ADHD) in preschool children. ADHD symptoms in siblings at 1.5, 3, and 5 years of age were investigated in a population-based sample from the prospective Norwegian Mother and Child Cohort Study. The longitudinal contributions of additive genetic, shared, twin-specific, and unique environmental influences were estimated using biometric structural equation models. Heritability of ADHD symptoms ranged from 54% to 70%. There was evidence of partially new genetic influences at successive ages, with genetic correlations ranging from .58 to .89. Contributions from shared environmental factors and twin-specific factors were minor. The importance of unique environmental effects appeared to increase across ages, and was mostly specific to a given age. There was no evidence suggesting that this pattern differs across males and females. Symptoms of ADHD are highly heritability in young children from as early as 1.5 years of age. Longitudinal stability of ADHD symptoms is mainly attributable to genetic influences, but there is also some evidence for age-specific genetic influences. These findings contribute to our understanding of development of ADHD early in life, and can guide future molecular genetics studies. En ligne : http://dx.doi.org/10.1017/s0954579418000731 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406

Externalising pathways to alcohol-related problems in emerging adulthood / Gemma HAMMERTON in Journal of Child Psychology and Psychiatry, 61-6 (June 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-6 (June 2020) . - p.721-731 Titre : Externalising pathways to alcohol-related problems in emerging adulthood Type de document : Texte imprimé et/ou numérique Auteurs : Gemma HAMMERTON, Auteur ; Alexis C. EDWARDS, Auteur ; Liam MAHEDY, Auteur ; Joseph MURRAY, Auteur ; Barbara MAUGHAN, Auteur ; Kenneth S. KENDLER, Auteur ; Matthew HICKMAN, Auteur ; Jon HERON, Auteur Article en page(s) : p.721-731 Langues : Anglais (eng) Mots-clés : Avon Longitudinal Study of Parents and Children  alcohol-related problems  conduct problems  criminal behaviour  mediation Index. décimale : PER Périodiques Résumé : BACKGROUND: Both 'early-onset persistent' and 'adolescent-onset' conduct problems (CPs) are associated with alcohol-related problems in emerging adulthood. The escalation of early CPs into criminal behaviour and heavy alcohol consumption prior to emerging adulthood are both likely to be important pathways. METHODS: Data were analysed from 3,038 young people in a UK birth cohort, the Avon Longitudinal Study of Parents and Children. The exposure was developmental trajectories of CPs ('low', 'childhood-limited', 'adolescent-onset' and 'early-onset persistent') between ages 4 and 13 years. The mediator was latent classes representing heavy alcohol consumption and/ or criminal behaviour at age 15 years. For the outcome, a quadratic latent growth curve was estimated to capture nonlinear change in alcohol-related problems between ages 18 and 23 years. RESULTS: Those with 'early-onset persistent' [b(95% CI) = 1.16 (0.17, 2.14)] and 'adolescent-onset' CPs [b(95% CI) = 1.31 (0.17, 2.45)] had higher levels of alcohol-related problems at age 18 years compared to those with 'low' CPs', but there was little evidence of an association with alcohol-related problems after age 19 years. There was evidence for an indirect effect of 'early-onset persistent' CPs [b(95% CI) = 1.12 (0.52, 1.72)] on alcohol-related problems at age 18 years via the latent classes of alcohol and criminal behaviour in adolescence. This was not found for 'adolescent-onset' CPs [b(95% CI) = 0.35 (-0.36, 1.07)]. CONCLUSIONS: Strong associations exist between early CPs, adolescent alcohol consumption and criminal behaviour and alcohol-related problems at age 18 years. Associations between early CPs and alcohol-related problems weakened considerably across emerging adulthood. En ligne : http://dx.doi.org/10.1111/jcpp.13167 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426 [article] Externalising pathways to alcohol-related problems in emerging adulthood [Texte imprimé et/ou numérique] / Gemma HAMMERTON, Auteur ; Alexis C. EDWARDS, Auteur ; Liam MAHEDY, Auteur ; Joseph MURRAY, Auteur ; Barbara MAUGHAN, Auteur ; Kenneth S. KENDLER, Auteur ; Matthew HICKMAN, Auteur ; Jon HERON, Auteur . - p.721-731. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-6 (June 2020) . - p.721-731 Mots-clés : Avon Longitudinal Study of Parents and Children  alcohol-related problems  conduct problems  criminal behaviour  mediation Index. décimale : PER Périodiques Résumé : BACKGROUND: Both 'early-onset persistent' and 'adolescent-onset' conduct problems (CPs) are associated with alcohol-related problems in emerging adulthood. The escalation of early CPs into criminal behaviour and heavy alcohol consumption prior to emerging adulthood are both likely to be important pathways. METHODS: Data were analysed from 3,038 young people in a UK birth cohort, the Avon Longitudinal Study of Parents and Children. The exposure was developmental trajectories of CPs ('low', 'childhood-limited', 'adolescent-onset' and 'early-onset persistent') between ages 4 and 13 years. The mediator was latent classes representing heavy alcohol consumption and/ or criminal behaviour at age 15 years. For the outcome, a quadratic latent growth curve was estimated to capture nonlinear change in alcohol-related problems between ages 18 and 23 years. RESULTS: Those with 'early-onset persistent' [b(95% CI) = 1.16 (0.17, 2.14)] and 'adolescent-onset' CPs [b(95% CI) = 1.31 (0.17, 2.45)] had higher levels of alcohol-related problems at age 18 years compared to those with 'low' CPs', but there was little evidence of an association with alcohol-related problems after age 19 years. There was evidence for an indirect effect of 'early-onset persistent' CPs [b(95% CI) = 1.12 (0.52, 1.72)] on alcohol-related problems at age 18 years via the latent classes of alcohol and criminal behaviour in adolescence. This was not found for 'adolescent-onset' CPs [b(95% CI) = 0.35 (-0.36, 1.07)]. CONCLUSIONS: Strong associations exist between early CPs, adolescent alcohol consumption and criminal behaviour and alcohol-related problems at age 18 years. Associations between early CPs and alcohol-related problems weakened considerably across emerging adulthood. En ligne : http://dx.doi.org/10.1111/jcpp.13167 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426

Maternal perinatal and concurrent depressive symptoms and child behavior problems: a sibling comparison study / Line C. GJERDE in Journal of Child Psychology and Psychiatry, 58-7 (July 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-7 (July 2017) . - p.779-786 Titre : Maternal perinatal and concurrent depressive symptoms and child behavior problems: a sibling comparison study Type de document : Texte imprimé et/ou numérique Auteurs : Line C. GJERDE, Auteur ; Espen Moen EILERTSEN, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Tom A. MCADAMS, Auteur ; Henrik Daae ZACHRISSON, Auteur ; Imac Maria ZAMBRANA, Auteur ; Espen RØYSAMB, Auteur ; Kenneth S. KENDLER, Auteur ; Eivind YSTROM, Auteur Article en page(s) : p.779-786 Langues : Anglais (eng) Mots-clés : Behavior problems  Child Behavior Checklist  depression  MoBa  prenatal  postnatal Index. décimale : PER Périodiques Résumé : Background Previous studies have found significant associations between maternal prenatal and postpartum depression and child behavior problems (CBP). The present study investigates whether associations remain in a prospective, longitudinal design adjusted for familial confounding. Methods The sample comprised 11,599 families including 17,830 siblings from the Norwegian Mother and Child Cohort study. Mothers reported depressive symptoms at gestational weeks 17 and 30, as well as 6 months, 1.5, 3, and 5 years postpartum. Fathers’ depression was measured at gestational week 17. At the last three time-points, child internalizing and externalizing problems were concurrently assessed. We performed multilevel analyses for internalizing and externalizing problems separately, using parental depression as predictors. Analyses were repeated using a sibling comparison design to adjust for familial confounding. Results All parental depressive time-points were significantly and positively associated with child internalizing and externalizing problems. After sibling comparison, however, only concurrent maternal depression was significantly associated with internalizing [estimate = 2.82 (1.91–3.73, 95% CI)] and externalizing problems [estimate = 2.40 (1.56–3.23, 95% CI)]. The effect of concurrent maternal depression on internalizing problems increased with child age. Conclusions Our findings do not support the notion that perinatal maternal depression is particularly detrimental to children's psychological development, as the most robust effects were found for maternal depression occurring during preschool years. En ligne : http://dx.doi.org/10.1111/jcpp.12704 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316 [article] Maternal perinatal and concurrent depressive symptoms and child behavior problems: a sibling comparison study [Texte imprimé et/ou numérique] / Line C. GJERDE, Auteur ; Espen Moen EILERTSEN, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Tom A. MCADAMS, Auteur ; Henrik Daae ZACHRISSON, Auteur ; Imac Maria ZAMBRANA, Auteur ; Espen RØYSAMB, Auteur ; Kenneth S. KENDLER, Auteur ; Eivind YSTROM, Auteur . - p.779-786. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-7 (July 2017) . - p.779-786 Mots-clés : Behavior problems  Child Behavior Checklist  depression  MoBa  prenatal  postnatal Index. décimale : PER Périodiques Résumé : Background Previous studies have found significant associations between maternal prenatal and postpartum depression and child behavior problems (CBP). The present study investigates whether associations remain in a prospective, longitudinal design adjusted for familial confounding. Methods The sample comprised 11,599 families including 17,830 siblings from the Norwegian Mother and Child Cohort study. Mothers reported depressive symptoms at gestational weeks 17 and 30, as well as 6 months, 1.5, 3, and 5 years postpartum. Fathers’ depression was measured at gestational week 17. At the last three time-points, child internalizing and externalizing problems were concurrently assessed. We performed multilevel analyses for internalizing and externalizing problems separately, using parental depression as predictors. Analyses were repeated using a sibling comparison design to adjust for familial confounding. Results All parental depressive time-points were significantly and positively associated with child internalizing and externalizing problems. After sibling comparison, however, only concurrent maternal depression was significantly associated with internalizing [estimate = 2.82 (1.91–3.73, 95% CI)] and externalizing problems [estimate = 2.40 (1.56–3.23, 95% CI)]. The effect of concurrent maternal depression on internalizing problems increased with child age. Conclusions Our findings do not support the notion that perinatal maternal depression is particularly detrimental to children's psychological development, as the most robust effects were found for maternal depression occurring during preschool years. En ligne : http://dx.doi.org/10.1111/jcpp.12704 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316

A pediatric twin study of brain morphometry / Gregory L. WALLACE in Journal of Child Psychology and Psychiatry, 47-10 (October 2006)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.987–993 Titre : A pediatric twin study of brain morphometry Type de document : Texte imprimé et/ou numérique Auteurs : Gregory L. WALLACE, Auteur ; Michael A. ROSENTHAL, Auteur ; Michael C. NEALE, Auteur ; Kenneth S. KENDLER, Auteur ; Liv S. CLASEN, Auteur ; Elizabeth A. MOLLOY, Auteur ; Sarah ORDAZ, Auteur ; Essi VIDING, Auteur ; Rhoshel LENROOT, Auteur ; J. Eric SCHMITT, Auteur ; Jay N. GIEDD, Auteur Année de publication : 2007 Article en page(s) : p.987–993 Langues : Anglais (eng) Mots-clés : Brain-development brain-imaging pediatric twin behavioral-genetics Index. décimale : PER Périodiques Résumé : Background: Longitudinal pediatric neuroimaging studies have demonstrated increasing volumes of white matter and regionally-specific inverted U shaped developmental trajectories of gray matter volumes during childhood and adolescence. Studies of monozygotic and dyzygotic twins during this developmental period allow exploration of genetic and non-genetic influences on these developmental trajectories. Method: Magnetic resonance imaging brain scans were acquired on a pediatric sample of 90 monozygotic twin pairs, 38 same-sex dyzygotic twin pairs, and 158 unrelated typically developing singletons. Structural equation modeling was used to estimate the additive genetic, common environment, and unique environment effects, as well as age by heritability interactions, on measures of brain volumes from these images. Results: Consistent with previous adult studies, additive genetic effects accounted for a substantial portion of variability in nearly all brain regions with the notable exception of the cerebellum. Significant age by heritability interactions were observed with gray matter volumes showing a reduction in heritability with increasing age, while white matter volume heritability increased with greater age. Conclusion: Understanding the relative contributions of genetic and nongenetic factors on developmental brain trajectories may have implications for better understanding brain-based disorders and typical cognitive development. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01676.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=788 [article] A pediatric twin study of brain morphometry [Texte imprimé et/ou numérique] / Gregory L. WALLACE, Auteur ; Michael A. ROSENTHAL, Auteur ; Michael C. NEALE, Auteur ; Kenneth S. KENDLER, Auteur ; Liv S. CLASEN, Auteur ; Elizabeth A. MOLLOY, Auteur ; Sarah ORDAZ, Auteur ; Essi VIDING, Auteur ; Rhoshel LENROOT, Auteur ; J. Eric SCHMITT, Auteur ; Jay N. GIEDD, Auteur . - 2007 . - p.987–993. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.987–993 Mots-clés : Brain-development brain-imaging pediatric twin behavioral-genetics Index. décimale : PER Périodiques Résumé : Background: Longitudinal pediatric neuroimaging studies have demonstrated increasing volumes of white matter and regionally-specific inverted U shaped developmental trajectories of gray matter volumes during childhood and adolescence. Studies of monozygotic and dyzygotic twins during this developmental period allow exploration of genetic and non-genetic influences on these developmental trajectories. Method: Magnetic resonance imaging brain scans were acquired on a pediatric sample of 90 monozygotic twin pairs, 38 same-sex dyzygotic twin pairs, and 158 unrelated typically developing singletons. Structural equation modeling was used to estimate the additive genetic, common environment, and unique environment effects, as well as age by heritability interactions, on measures of brain volumes from these images. Results: Consistent with previous adult studies, additive genetic effects accounted for a substantial portion of variability in nearly all brain regions with the notable exception of the cerebellum. Significant age by heritability interactions were observed with gray matter volumes showing a reduction in heritability with increasing age, while white matter volume heritability increased with greater age. Conclusion: Understanding the relative contributions of genetic and nongenetic factors on developmental brain trajectories may have implications for better understanding brain-based disorders and typical cognitive development. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01676.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=788

Young men's behavioral competencies and risk of alcohol use disorder in emerging adulthood: Early protective effects of parental education / Katherine J. KARRIKER-JAFFE in Development and Psychopathology, 33-1 (February 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-1 (February 2021) . - p.135-148 Titre : Young men's behavioral competencies and risk of alcohol use disorder in emerging adulthood: Early protective effects of parental education Type de document : Texte imprimé et/ou numérique Auteurs : Katherine J. KARRIKER-JAFFE, Auteur ; Sara L. LÖNN, Auteur ; Won K. COOK, Auteur ; Kenneth S. KENDLER, Auteur ; Kristina SUNDQUIST, Auteur Article en page(s) : p.135-148 Langues : Anglais (eng) Mots-clés : academic competence  alcohol use disorder  criminal behavior  externalizing behavior  socioeconomic status Index. décimale : PER Périodiques Résumé : We investigate how early exposure to parental externalizing behaviors (EB) may contribute to development of alcohol use disorders (AUD) in young adulthood, testing a developmental cascade model focused on competencies in three domains (academic, conduct, and work) in adolescence and emerging adulthood, and examining whether high parental education can buffer negative effects of parental EB and other early risk factors. We use data from 451,054 Swedish-born men included in the national conscript register. Structural equation models showed parental EB was associated with academic and behavioral problems during adolescence, as well as with lower resilience, more criminal behavior, and reduced social integration during emerging adulthood. These pathways led to elevated rates of AUD in emerging and young adulthood. Multiple groups analysis showed most of the indirect pathways from parental EB to AUD were present but buffered by higher parental education, suggesting early life experiences and competencies matter more for young men from lower socioeconomic status (SES) families than from higher SES families. Developmental competencies in school, conduct, and work are important precursors to the development of AUD by young adulthood that are predicted by parental EB. Occupational success may be an overlooked source of resilience for young men from low-SES families. En ligne : http://dx.doi.org/10.1017/s0954579419001640 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442 [article] Young men's behavioral competencies and risk of alcohol use disorder in emerging adulthood: Early protective effects of parental education [Texte imprimé et/ou numérique] / Katherine J. KARRIKER-JAFFE, Auteur ; Sara L. LÖNN, Auteur ; Won K. COOK, Auteur ; Kenneth S. KENDLER, Auteur ; Kristina SUNDQUIST, Auteur . - p.135-148. Langues : Anglais (eng) in Development and Psychopathology > 33-1 (February 2021) . - p.135-148 Mots-clés : academic competence  alcohol use disorder  criminal behavior  externalizing behavior  socioeconomic status Index. décimale : PER Périodiques Résumé : We investigate how early exposure to parental externalizing behaviors (EB) may contribute to development of alcohol use disorders (AUD) in young adulthood, testing a developmental cascade model focused on competencies in three domains (academic, conduct, and work) in adolescence and emerging adulthood, and examining whether high parental education can buffer negative effects of parental EB and other early risk factors. We use data from 451,054 Swedish-born men included in the national conscript register. Structural equation models showed parental EB was associated with academic and behavioral problems during adolescence, as well as with lower resilience, more criminal behavior, and reduced social integration during emerging adulthood. These pathways led to elevated rates of AUD in emerging and young adulthood. Multiple groups analysis showed most of the indirect pathways from parental EB to AUD were present but buffered by higher parental education, suggesting early life experiences and competencies matter more for young men from lower socioeconomic status (SES) families than from higher SES families. Developmental competencies in school, conduct, and work are important precursors to the development of AUD by young adulthood that are predicted by parental EB. Occupational success may be an overlooked source of resilience for young men from low-SES families. En ligne : http://dx.doi.org/10.1017/s0954579419001640 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442

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