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Auteur Tom A. MCADAMS |
Documents disponibles écrits par cet auteur (9)



Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence / Giorgia MICHELINI in Journal of Child Psychology and Psychiatry, 56-4 (April 2015)
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Titre : Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Giorgia MICHELINI, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Tom A. MCADAMS, Auteur Article en page(s) : p.423-431 Langues : Anglais (eng) Mots-clés : Anxiety ADH problems genetics twins adolescence Index. décimale : PER Périodiques Résumé : Background Anxiety and attention-deficit/hyperactivity (ADH) problems are common in adolescence, often co-occur, and are characterised by high heterogeneity in their phenotypic expressions. Although it is known that anxiety and ADH problems correlate, the relationships between subtypes of anxiety and ADH problems have been scarcely investigated. Methods Using a large population sample of adolescent twins and siblings we explored the phenotypic and aetiological association between anxiety subtypes (panic/agoraphobia, separation anxiety, social anxiety, physical injury fears, obsessive-compulsive symptoms and generalised anxiety) and the two ADH dimensions (attention problems and hyperactivity/impulsivity). Both phenotypes were assessed using self-report questionnaires. Results The association between ADH problems and anxiety could be entirely attributed to attention problems, not hyperactivity/impulsivity. Most of the correlations between anxiety subtypes and attention problems showed an approximately equal role of genetic and nonshared environmental factors. Conclusions The high heterogeneity within anxiety and ADH problems should be taken into account in order to better understand comorbidity between them. En ligne : http://dx.doi.org/10.1111/jcpp.12318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.423-431[article] Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence [Texte imprimé et/ou numérique] / Giorgia MICHELINI, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Tom A. MCADAMS, Auteur . - p.423-431.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.423-431
Mots-clés : Anxiety ADH problems genetics twins adolescence Index. décimale : PER Périodiques Résumé : Background Anxiety and attention-deficit/hyperactivity (ADH) problems are common in adolescence, often co-occur, and are characterised by high heterogeneity in their phenotypic expressions. Although it is known that anxiety and ADH problems correlate, the relationships between subtypes of anxiety and ADH problems have been scarcely investigated. Methods Using a large population sample of adolescent twins and siblings we explored the phenotypic and aetiological association between anxiety subtypes (panic/agoraphobia, separation anxiety, social anxiety, physical injury fears, obsessive-compulsive symptoms and generalised anxiety) and the two ADH dimensions (attention problems and hyperactivity/impulsivity). Both phenotypes were assessed using self-report questionnaires. Results The association between ADH problems and anxiety could be entirely attributed to attention problems, not hyperactivity/impulsivity. Most of the correlations between anxiety subtypes and attention problems showed an approximately equal role of genetic and nonshared environmental factors. Conclusions The high heterogeneity within anxiety and ADH problems should be taken into account in order to better understand comorbidity between them. En ligne : http://dx.doi.org/10.1111/jcpp.12318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 Annual Research Review: Towards a deeper understanding of nature and nurture: combining family-based quasi-experimental methods with genomic data / Tom A. MCADAMS in Journal of Child Psychology and Psychiatry, 64-4 (April 2023)
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Titre : Annual Research Review: Towards a deeper understanding of nature and nurture: combining family-based quasi-experimental methods with genomic data Type de document : Texte imprimé et/ou numérique Auteurs : Tom A. MCADAMS, Auteur ; Rosa CHEESMAN, Auteur ; Yasmin I. AHMADZADEH, Auteur Article en page(s) : p.693-707 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Distinguishing between the effects of nature and nurture constitutes a major research goal for those interested in understanding human development. It is known, for example, that many parent traits predict mental health outcomes in children, but the causal processes underlying such associations are often unclear. Family-based quasi-experimental designs such as sibling comparison, adoption and extended family studies have been used for decades to distinguish the genetic transmission of risk from the environmental effects family members potentially have on one another. Recently, these designs have been combined with genomic data, and this combination is fuelling a range of exciting methodological advances. In this review we explore these advances - highlighting the ways in which they have been applied to date and considering what they are likely to teach us in the coming years about the aetiology and intergenerational transmission of psychopathology. En ligne : https://doi.org/10.1111/jcpp.13720 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501
in Journal of Child Psychology and Psychiatry > 64-4 (April 2023) . - p.693-707[article] Annual Research Review: Towards a deeper understanding of nature and nurture: combining family-based quasi-experimental methods with genomic data [Texte imprimé et/ou numérique] / Tom A. MCADAMS, Auteur ; Rosa CHEESMAN, Auteur ; Yasmin I. AHMADZADEH, Auteur . - p.693-707.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 64-4 (April 2023) . - p.693-707
Index. décimale : PER Périodiques Résumé : Distinguishing between the effects of nature and nurture constitutes a major research goal for those interested in understanding human development. It is known, for example, that many parent traits predict mental health outcomes in children, but the causal processes underlying such associations are often unclear. Family-based quasi-experimental designs such as sibling comparison, adoption and extended family studies have been used for decades to distinguish the genetic transmission of risk from the environmental effects family members potentially have on one another. Recently, these designs have been combined with genomic data, and this combination is fuelling a range of exciting methodological advances. In this review we explore these advances - highlighting the ways in which they have been applied to date and considering what they are likely to teach us in the coming years about the aetiology and intergenerational transmission of psychopathology. En ligne : https://doi.org/10.1111/jcpp.13720 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children / Tom A. MCADAMS in Journal of Child Psychology and Psychiatry, 58-1 (January 2017)
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Titre : Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children Type de document : Texte imprimé et/ou numérique Auteurs : Tom A. MCADAMS, Auteur ; Frühling V. RIJSDIJK, Auteur ; Jurgita NARUSYTE, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur ; Erica SPOTTS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Paul LICHTENSTEIN, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.46-54 Langues : Anglais (eng) Mots-clés : Adolescence parenting parent–child relationships children-of-twins self-esteem Index. décimale : PER Périodiques Résumé : Background Low self-worth during adolescence predicts a range of emotional and behavioural problems. As such, identifying potential sources of influence on self-worth is important. Aspects of the parent–child relationship are often associated with adolescent self-worth but to date it is unclear whether such associations may be attributable to familial confounding (e.g. genetic relatedness). We set out to clarify the nature of relationships between parental expressed affection and adolescent self-worth, and parent–child closeness and adolescent self-worth. Methods We used data from the Twin and Offspring Study in Sweden, a children-of-twins sample comprising 909 adult twin pairs with adolescent children. Using these data we were able to apply structural equation models with which we could examine whether associations remained after accounting for genetic transmission. Results Results demonstrated that parent–child closeness and parental-expressed affection were both phenotypically associated with adolescent self-worth. Associations could not be attributed to genetic relatedness between parent and child. Conclusions Parent–child closeness and parental affection are associated with adolescent self-worth above and beyond effects attributable to genetic relatedness. Data were cross-sectional, so the direction of effects cannot be confirmed but findings support the notion that positive parent–child relationships increase adolescent self-worth. En ligne : http://dx.doi.org/10.1111/jcpp.12600 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298
in Journal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.46-54[article] Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children [Texte imprimé et/ou numérique] / Tom A. MCADAMS, Auteur ; Frühling V. RIJSDIJK, Auteur ; Jurgita NARUSYTE, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur ; Erica SPOTTS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Paul LICHTENSTEIN, Auteur ; Thalia C. ELEY, Auteur . - p.46-54.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.46-54
Mots-clés : Adolescence parenting parent–child relationships children-of-twins self-esteem Index. décimale : PER Périodiques Résumé : Background Low self-worth during adolescence predicts a range of emotional and behavioural problems. As such, identifying potential sources of influence on self-worth is important. Aspects of the parent–child relationship are often associated with adolescent self-worth but to date it is unclear whether such associations may be attributable to familial confounding (e.g. genetic relatedness). We set out to clarify the nature of relationships between parental expressed affection and adolescent self-worth, and parent–child closeness and adolescent self-worth. Methods We used data from the Twin and Offspring Study in Sweden, a children-of-twins sample comprising 909 adult twin pairs with adolescent children. Using these data we were able to apply structural equation models with which we could examine whether associations remained after accounting for genetic transmission. Results Results demonstrated that parent–child closeness and parental-expressed affection were both phenotypically associated with adolescent self-worth. Associations could not be attributed to genetic relatedness between parent and child. Conclusions Parent–child closeness and parental affection are associated with adolescent self-worth above and beyond effects attributable to genetic relatedness. Data were cross-sectional, so the direction of effects cannot be confirmed but findings support the notion that positive parent–child relationships increase adolescent self-worth. En ligne : http://dx.doi.org/10.1111/jcpp.12600 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders / Hannah M. BROWN in Journal of Child Psychology and Psychiatry, 54-6 (June 2013)
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Titre : Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hannah M. BROWN, Auteur ; Tom A. MCADAMS, Auteur ; Kathryn J. LESTER, Auteur ; Robert GOODMAN, Auteur ; David M. CLARK, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.678-685 Langues : Anglais (eng) Mots-clés : Anxiety attention children familial risk Index. décimale : PER Périodiques Résumé : Background: Twin studies in children reveal that familial aggregation of anxiety disorders is due to both genetic and environmental factors. Cognitive biases for threat information are considered a robust characteristic of childhood anxiety. However, little is known regarding the underlying aetiology of such biases and their role in anxiety disorders. Method: A face version of the dot-probe task measuring attentional biases for negative (anger, fear, sad, disgust) and positive (happy) facial expressions was completed by 600, 8-year-old twins; the largest study of its kind. Twin correlations for attentional bias scores were compared to estimate genetic and environmental effects. Parent-report diagnostic interviews identified children with an anxiety disorder. Indices of inferred genetic and familial risk for anxiety disorders were created for each child. Data were analysed using a series of logistic regressions. Results: Anxious children showed greater attentional avoidance of negative faces than nonanxious children; t (548) = 2.55, p .05. Attentional avoidance was not under genetic or shared environmental influence. Risk for anxiety disorders was predicted by familial factors. Both attentional avoidance and inferred familial risk were significant but independent predictors of anxiety disorders (ORs = .65 and 3.64, respectively). Conclusions: Anxiety-related attentional biases and familial risk play important but independent roles in childhood anxiety disorders. If replicated, these findings indicate that links between genetic risk and anxiety disorders lie outside the domain of attentional processes. En ligne : http://dx.doi.org/10.1111/jcpp.12024 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=200
in Journal of Child Psychology and Psychiatry > 54-6 (June 2013) . - p.678-685[article] Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders [Texte imprimé et/ou numérique] / Hannah M. BROWN, Auteur ; Tom A. MCADAMS, Auteur ; Kathryn J. LESTER, Auteur ; Robert GOODMAN, Auteur ; David M. CLARK, Auteur ; Thalia C. ELEY, Auteur . - p.678-685.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 54-6 (June 2013) . - p.678-685
Mots-clés : Anxiety attention children familial risk Index. décimale : PER Périodiques Résumé : Background: Twin studies in children reveal that familial aggregation of anxiety disorders is due to both genetic and environmental factors. Cognitive biases for threat information are considered a robust characteristic of childhood anxiety. However, little is known regarding the underlying aetiology of such biases and their role in anxiety disorders. Method: A face version of the dot-probe task measuring attentional biases for negative (anger, fear, sad, disgust) and positive (happy) facial expressions was completed by 600, 8-year-old twins; the largest study of its kind. Twin correlations for attentional bias scores were compared to estimate genetic and environmental effects. Parent-report diagnostic interviews identified children with an anxiety disorder. Indices of inferred genetic and familial risk for anxiety disorders were created for each child. Data were analysed using a series of logistic regressions. Results: Anxious children showed greater attentional avoidance of negative faces than nonanxious children; t (548) = 2.55, p .05. Attentional avoidance was not under genetic or shared environmental influence. Risk for anxiety disorders was predicted by familial factors. Both attentional avoidance and inferred familial risk were significant but independent predictors of anxiety disorders (ORs = .65 and 3.64, respectively). Conclusions: Anxiety-related attentional biases and familial risk play important but independent roles in childhood anxiety disorders. If replicated, these findings indicate that links between genetic risk and anxiety disorders lie outside the domain of attentional processes. En ligne : http://dx.doi.org/10.1111/jcpp.12024 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=200 Developmental change in the association between adolescent depressive symptoms and the home environment: results from a longitudinal, genetically informative investigation / Laurie J. HANNIGAN in Journal of Child Psychology and Psychiatry, 58-7 (July 2017)
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Titre : Developmental change in the association between adolescent depressive symptoms and the home environment: results from a longitudinal, genetically informative investigation Type de document : Texte imprimé et/ou numérique Auteurs : Laurie J. HANNIGAN, Auteur ; Tom A. MCADAMS, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.787-797 Langues : Anglais (eng) Mots-clés : Depression adolescence home environment parenting gene–environment correlation Index. décimale : PER Périodiques Résumé : Background Depression is already highly prevalent by late adolescence, indicating that research into its developmental emergence should consider earlier risk factors and environmental contexts. The home environment is a key context for children and adolescents throughout development. However, the nature of relationships that exist between aspects of the home environment and the development of depressive symptoms cannot be assumed. Genetically informative studies have been used to provide insights about the aetiology of such relationships, often finding them to be partly confounded by the influence of children's genes. Here, we investigate developmental change in the aetiology of the association between aspects of the home environment and depressive symptoms at the onset of adolescence. Methods We used longitudinal child- and parent-report data from >5,000 twin pairs enrolled in the UK-representative Twins Early Development Study. Multivariate, genetically sensitive structural equation models were used to decompose latent variance and covariance in depressive symptoms (measured at 12 and 16 years) and aspects of the home environment (at 9 and 14 years) into genetic and environmental influences. Results Going from childhood to adolescence, genetic influences accounted for an increasing proportion of the association [30% (16–42) of r = .44 in childhood; 40% (25–61) of r = .43 in adolescence], at the expense of shared environmental influences, which decreased from 70% (58–83) to 48% (29–62). Unique environmental influences accounted for a significant proportion of the association in adolescence only [12% (06–18)]. Developmental changes could largely be attributed to subtle shifts in the relative importance of stable aetiological factors, rather than the emergence of influences unique to adolescence. Conclusions These findings emphasise the importance of developmental and aetiological context in interpreting associations between aspects of the home environment and child emotional outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.12689 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316
in Journal of Child Psychology and Psychiatry > 58-7 (July 2017) . - p.787-797[article] Developmental change in the association between adolescent depressive symptoms and the home environment: results from a longitudinal, genetically informative investigation [Texte imprimé et/ou numérique] / Laurie J. HANNIGAN, Auteur ; Tom A. MCADAMS, Auteur ; Thalia C. ELEY, Auteur . - p.787-797.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-7 (July 2017) . - p.787-797
Mots-clés : Depression adolescence home environment parenting gene–environment correlation Index. décimale : PER Périodiques Résumé : Background Depression is already highly prevalent by late adolescence, indicating that research into its developmental emergence should consider earlier risk factors and environmental contexts. The home environment is a key context for children and adolescents throughout development. However, the nature of relationships that exist between aspects of the home environment and the development of depressive symptoms cannot be assumed. Genetically informative studies have been used to provide insights about the aetiology of such relationships, often finding them to be partly confounded by the influence of children's genes. Here, we investigate developmental change in the aetiology of the association between aspects of the home environment and depressive symptoms at the onset of adolescence. Methods We used longitudinal child- and parent-report data from >5,000 twin pairs enrolled in the UK-representative Twins Early Development Study. Multivariate, genetically sensitive structural equation models were used to decompose latent variance and covariance in depressive symptoms (measured at 12 and 16 years) and aspects of the home environment (at 9 and 14 years) into genetic and environmental influences. Results Going from childhood to adolescence, genetic influences accounted for an increasing proportion of the association [30% (16–42) of r = .44 in childhood; 40% (25–61) of r = .43 in adolescence], at the expense of shared environmental influences, which decreased from 70% (58–83) to 48% (29–62). Unique environmental influences accounted for a significant proportion of the association in adolescence only [12% (06–18)]. Developmental changes could largely be attributed to subtle shifts in the relative importance of stable aetiological factors, rather than the emergence of influences unique to adolescence. Conclusions These findings emphasise the importance of developmental and aetiological context in interpreting associations between aspects of the home environment and child emotional outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.12689 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316 Maternal perinatal and concurrent depressive symptoms and child behavior problems: a sibling comparison study / Line C. GJERDE in Journal of Child Psychology and Psychiatry, 58-7 (July 2017)
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PermalinkOn the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families / Espen M. EILERTSEN in Journal of Child Psychology and Psychiatry, 63-10 (October 2022)
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PermalinkParental criticism and adolescent internalising symptoms: using a Children-of-Twins design with power calculations to account for genetic influence / Yasmin I. AHMADZADEH in Journal of Child Psychology and Psychiatry, 63-5 (May 2022)
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PermalinkSocioeconomic status and risk for child psychopathology: exploring gene?environment interaction in the presence of gene?environment correlation using extended families in the Norwegian Mother, Father and Child Birth Cohort Study / Yasmin AHMADZADEH ; Daniel L. WECHSLER ; Torkild H. LYNGSTAD ; Christopher RAYNER ; Espen M. EILERTSEN ; Helena M.S. ZAVOS ; Eivind YSTROM ; Tom A. MCADAMS in Journal of Child Psychology and Psychiatry, 65-2 (February 2024)
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