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9 recherche sur le mot-clé 'MoBa'




Functional Outcomes of Children Identified Early in the Developmental Period as at Risk for ASD Utilizing the The Norwegian Mother, Father and Child Cohort Study (MoBa) / Nina STENBERG in Journal of Autism and Developmental Disorders, 51-3 (March 2021)
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Titre : Functional Outcomes of Children Identified Early in the Developmental Period as at Risk for ASD Utilizing the The Norwegian Mother, Father and Child Cohort Study (MoBa) Type de document : Texte imprimé et/ou numérique Auteurs : Nina STENBERG, Auteur ; Synnve SCHJØLBERG, Auteur ; Frederick SHIC, Auteur ; Fred R. VOLKMAR, Auteur ; Anne-Siri ØYEN, Auteur ; Michaeline BRESNAHAN, Auteur ; Britt Kveim SVENDSEN, Auteur ; Stephen VON TETZCHNER, Auteur ; Nina Torheim THRONÆS, Auteur ; Suzanne MACARI, Auteur ; Domenic V. CICCHETTI, Auteur ; Katarzyna CHAWARSKA, Auteur ; Pål SUREN, Auteur ; Roald A. ØIEN, Auteur Article en page(s) : p.922-932 Langues : Anglais (eng) Mots-clés : Ados Autism spectrum disorders Cognition Early identification Father and child cohort study Language MoBa Norwegian mother Screening Vineland Index. décimale : PER Périodiques Résumé : Early identification of autism spectrum disorder (ASD) is regarded as crucial for swift access to early intervention and, subsequently, better outcomes later in life. However, current instruments miss large proportions of children who later go on to be diagnosed with ASD, raising a question of what these instruments measure. The present study utilized data from the Norwegian Mother, Father, and Child Cohort Study and the Autism Birth Cohort study to explore the subsequent developmental and diagnostic characteristics of children raising developmental concern on the six-critical discriminative item criterion of the M-CHAT (DFA6) at 18 months of age (N = 834). The DFA6 identified 28.8% of children diagnosed with ASD (N = 163), but 4.4% with language disorder (N = 188) and 81.3% with intellectual disability (N = 32) without ASD. Scoring in the «at-risk» range was associated with lower IQ, impaired functional language, and greater severity of autism symptoms whether children had ASD or not. En ligne : http://dx.doi.org/10.1007/s10803-020-04539-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443
in Journal of Autism and Developmental Disorders > 51-3 (March 2021) . - p.922-932[article] Functional Outcomes of Children Identified Early in the Developmental Period as at Risk for ASD Utilizing the The Norwegian Mother, Father and Child Cohort Study (MoBa) [Texte imprimé et/ou numérique] / Nina STENBERG, Auteur ; Synnve SCHJØLBERG, Auteur ; Frederick SHIC, Auteur ; Fred R. VOLKMAR, Auteur ; Anne-Siri ØYEN, Auteur ; Michaeline BRESNAHAN, Auteur ; Britt Kveim SVENDSEN, Auteur ; Stephen VON TETZCHNER, Auteur ; Nina Torheim THRONÆS, Auteur ; Suzanne MACARI, Auteur ; Domenic V. CICCHETTI, Auteur ; Katarzyna CHAWARSKA, Auteur ; Pål SUREN, Auteur ; Roald A. ØIEN, Auteur . - p.922-932.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-3 (March 2021) . - p.922-932
Mots-clés : Ados Autism spectrum disorders Cognition Early identification Father and child cohort study Language MoBa Norwegian mother Screening Vineland Index. décimale : PER Périodiques Résumé : Early identification of autism spectrum disorder (ASD) is regarded as crucial for swift access to early intervention and, subsequently, better outcomes later in life. However, current instruments miss large proportions of children who later go on to be diagnosed with ASD, raising a question of what these instruments measure. The present study utilized data from the Norwegian Mother, Father, and Child Cohort Study and the Autism Birth Cohort study to explore the subsequent developmental and diagnostic characteristics of children raising developmental concern on the six-critical discriminative item criterion of the M-CHAT (DFA6) at 18 months of age (N = 834). The DFA6 identified 28.8% of children diagnosed with ASD (N = 163), but 4.4% with language disorder (N = 188) and 81.3% with intellectual disability (N = 32) without ASD. Scoring in the «at-risk» range was associated with lower IQ, impaired functional language, and greater severity of autism symptoms whether children had ASD or not. En ligne : http://dx.doi.org/10.1007/s10803-020-04539-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443 Age of walking and intellectual ability in autism spectrum disorder and other neurodevelopmental disorders: a population-based study / A. HAVDAHL in Journal of Child Psychology and Psychiatry, 62-9 (September 2021)
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Titre : Age of walking and intellectual ability in autism spectrum disorder and other neurodevelopmental disorders: a population-based study Type de document : Texte imprimé et/ou numérique Auteurs : A. HAVDAHL, Auteur ; C. FARMER, Auteur ; Synnve SCHJØLBERG, Auteur ; A. S. ØYEN, Auteur ; P. SURÉN, Auteur ; T. REICHBORN-KJENNERUD, Auteur ; P. MAGNUS, Auteur ; Michaeline BRESNAHAN, Auteur ; M. HORNIG, Auteur ; E. SUSSER, Auteur ; W. I. LIPKIN, Auteur ; C. LORD, Auteur ; C. STOLTENBERG, Auteur ; A. THURM, Auteur ; Somer L. BISHOP, Auteur Article en page(s) : p.1070-1078 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/epidemiology Child Cohort Studies Humans Intellectual Disability/epidemiology Neurodevelopmental Disorders/epidemiology Walking Intellectual disability MoBa epidemiology gross motor milestones late walking All profits from their research are donated to charity. The other authors report no conflicts of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Delayed walking is common in intellectual disability (ID) but may be less common when ID occurs with autism spectrum disorder (ASD). Previous studies examining this were limited by reliance on clinical samples and exclusion of children with severe motor deficits. OBJECTIVE: To examine in a population-based sample if age of walking is differentially related to intellectual ability in children with ASD versus other neurodevelopmental disorders (NDD). METHODS: Participants were from the nested Autism Birth Cohort Study of the Norwegian Mother, Father and Child Cohort Study (MoBa). Cox proportional hazards regression assessed if diagnosis (ASD n = 212 vs. NDD n = 354), continuous nonverbal IQ, and their interaction, were associated with continuous age of walking. RESULTS: The relationship between nonverbal IQ and age of walking was stronger for NDD than for ASD (Group × nonverbal IQ interaction, ?(2) = 13.93, p = .0002). This interaction was characterized by a 21% decrease in the likelihood of walking onset at any given time during the observation period per 10-point decrease in nonverbal IQ (hazard ratio = 0.79, 95% CI: 0.78-0.85) in the NDD group compared to 8% (hazard ratio = 0.92, 95% CI: 0.86-0.98) in the ASD group. CONCLUSIONS: The finding that age of walking is less strongly related to low intellectual ability in children with ASD than in children without other NDDs supports the hypothesis that ID in ASD may result from heterogeneous developmental pathways. Late walking may be a useful stratification variable in etiological research focused on ASD and other NDDs. En ligne : http://dx.doi.org/10.1111/jcpp.13369 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-9 (September 2021) . - p.1070-1078[article] Age of walking and intellectual ability in autism spectrum disorder and other neurodevelopmental disorders: a population-based study [Texte imprimé et/ou numérique] / A. HAVDAHL, Auteur ; C. FARMER, Auteur ; Synnve SCHJØLBERG, Auteur ; A. S. ØYEN, Auteur ; P. SURÉN, Auteur ; T. REICHBORN-KJENNERUD, Auteur ; P. MAGNUS, Auteur ; Michaeline BRESNAHAN, Auteur ; M. HORNIG, Auteur ; E. SUSSER, Auteur ; W. I. LIPKIN, Auteur ; C. LORD, Auteur ; C. STOLTENBERG, Auteur ; A. THURM, Auteur ; Somer L. BISHOP, Auteur . - p.1070-1078.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-9 (September 2021) . - p.1070-1078
Mots-clés : Autism Spectrum Disorder/epidemiology Child Cohort Studies Humans Intellectual Disability/epidemiology Neurodevelopmental Disorders/epidemiology Walking Intellectual disability MoBa epidemiology gross motor milestones late walking All profits from their research are donated to charity. The other authors report no conflicts of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Delayed walking is common in intellectual disability (ID) but may be less common when ID occurs with autism spectrum disorder (ASD). Previous studies examining this were limited by reliance on clinical samples and exclusion of children with severe motor deficits. OBJECTIVE: To examine in a population-based sample if age of walking is differentially related to intellectual ability in children with ASD versus other neurodevelopmental disorders (NDD). METHODS: Participants were from the nested Autism Birth Cohort Study of the Norwegian Mother, Father and Child Cohort Study (MoBa). Cox proportional hazards regression assessed if diagnosis (ASD n = 212 vs. NDD n = 354), continuous nonverbal IQ, and their interaction, were associated with continuous age of walking. RESULTS: The relationship between nonverbal IQ and age of walking was stronger for NDD than for ASD (Group × nonverbal IQ interaction, ?(2) = 13.93, p = .0002). This interaction was characterized by a 21% decrease in the likelihood of walking onset at any given time during the observation period per 10-point decrease in nonverbal IQ (hazard ratio = 0.79, 95% CI: 0.78-0.85) in the NDD group compared to 8% (hazard ratio = 0.92, 95% CI: 0.86-0.98) in the ASD group. CONCLUSIONS: The finding that age of walking is less strongly related to low intellectual ability in children with ASD than in children without other NDDs supports the hypothesis that ID in ASD may result from heterogeneous developmental pathways. Late walking may be a useful stratification variable in etiological research focused on ASD and other NDDs. En ligne : http://dx.doi.org/10.1111/jcpp.13369 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 Early manifestations of genetic risk for neurodevelopmental disorders / Ragna Bugge ASKELAND in Journal of Child Psychology and Psychiatry, 63-7 (July 2022)
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Titre : Early manifestations of genetic risk for neurodevelopmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : Ragna Bugge ASKELAND, Auteur ; Laurie J. HANNIGAN, Auteur ; Helga ASK, Auteur ; Ziada AYORECH, Auteur ; Martin TESLI, Auteur ; Elizabeth CORFIELD, Auteur ; Per MAGNUS, Auteur ; Pål Rasmus NJØLSTAD, Auteur ; Ole A. ANDREASSEN, Auteur ; George DAVEY SMITH, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Alexandra HAVDAHL, Auteur Article en page(s) : p.810-819 Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/complications/epidemiology/genetics Autism Spectrum Disorder/complications/epidemiology/genetics Child Child, Preschool Cohort Studies Female Humans Male Mothers Neurodevelopmental Disorders/complications/epidemiology/genetics Risk Factors Adhd MoBa Polygenic risk score autism hyperactivity inattention language and motor difficulties neurodevelopmental disorders repetitive behavior schizophrenia social communication Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (autism) and schizophrenia are highly heritable neurodevelopmental disorders, affecting the lives of many individuals. It is important to increase our understanding of how the polygenic risk for neurodevelopmental disorders manifests during childhood in boys and girls. METHODS: Polygenic risk scores (PRS) for ADHD, autism and schizophrenia were calculated in a subsample of 15?205 children from the Norwegian Mother, Father and Child Cohort Study (MoBa). Mother-reported traits of repetitive behavior, social communication, language and motor difficulties, hyperactivity and inattention were measured in children at 6 and 18?months, 3, 5 and 8?years. Linear regression models in a multigroup framework were used to investigate associations between the three PRS and dimensional trait measures in MoBa, using sex as a grouping variable. RESULTS: Before the age of 2, the ADHD PRS was robustly associated with hyperactivity and inattention, with increasing strength up to 8?years, and with language difficulties at age 5 and 8. The autism PRS was robustly associated with language difficulties at 18?months, motor difficulties at 36?months, and hyperactivity and inattention at 8?years. We did not identify robust associations for the schizophrenia PRS. In general, the PRS associations were similar in boys and girls. The association between ADHD PRS and hyperactivity at 18?months was, however, stronger in boys. CONCLUSIONS: Polygenic risk for autism and ADHD in the general population manifests early in childhood and broadly across behavioral measures of neurodevelopmental traits. En ligne : http://dx.doi.org/10.1111/jcpp.13528 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477
in Journal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.810-819[article] Early manifestations of genetic risk for neurodevelopmental disorders [Texte imprimé et/ou numérique] / Ragna Bugge ASKELAND, Auteur ; Laurie J. HANNIGAN, Auteur ; Helga ASK, Auteur ; Ziada AYORECH, Auteur ; Martin TESLI, Auteur ; Elizabeth CORFIELD, Auteur ; Per MAGNUS, Auteur ; Pål Rasmus NJØLSTAD, Auteur ; Ole A. ANDREASSEN, Auteur ; George DAVEY SMITH, Auteur ; Ted REICHBORN-KJENNERUD, Auteur ; Alexandra HAVDAHL, Auteur . - p.810-819.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-7 (July 2022) . - p.810-819
Mots-clés : Attention Deficit Disorder with Hyperactivity/complications/epidemiology/genetics Autism Spectrum Disorder/complications/epidemiology/genetics Child Child, Preschool Cohort Studies Female Humans Male Mothers Neurodevelopmental Disorders/complications/epidemiology/genetics Risk Factors Adhd MoBa Polygenic risk score autism hyperactivity inattention language and motor difficulties neurodevelopmental disorders repetitive behavior schizophrenia social communication Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (autism) and schizophrenia are highly heritable neurodevelopmental disorders, affecting the lives of many individuals. It is important to increase our understanding of how the polygenic risk for neurodevelopmental disorders manifests during childhood in boys and girls. METHODS: Polygenic risk scores (PRS) for ADHD, autism and schizophrenia were calculated in a subsample of 15?205 children from the Norwegian Mother, Father and Child Cohort Study (MoBa). Mother-reported traits of repetitive behavior, social communication, language and motor difficulties, hyperactivity and inattention were measured in children at 6 and 18?months, 3, 5 and 8?years. Linear regression models in a multigroup framework were used to investigate associations between the three PRS and dimensional trait measures in MoBa, using sex as a grouping variable. RESULTS: Before the age of 2, the ADHD PRS was robustly associated with hyperactivity and inattention, with increasing strength up to 8?years, and with language difficulties at age 5 and 8. The autism PRS was robustly associated with language difficulties at 18?months, motor difficulties at 36?months, and hyperactivity and inattention at 8?years. We did not identify robust associations for the schizophrenia PRS. In general, the PRS associations were similar in boys and girls. The association between ADHD PRS and hyperactivity at 18?months was, however, stronger in boys. CONCLUSIONS: Polygenic risk for autism and ADHD in the general population manifests early in childhood and broadly across behavioral measures of neurodevelopmental traits. En ligne : http://dx.doi.org/10.1111/jcpp.13528 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 Measuring autism-associated traits in the general population: Factor structure and measurement invariance across sex and diagnosis status of the Social Communication Questionnaire / Ragna BUGGE ASKELAND ; Stian BARBO VALAND ; Anne-Siri ØYEN ; Synnve SCHJØLBERG ; Vanessa H. BAL ; Somer L. BISHOP ; Camilla STOLTENBERG ; Tilmann VON SOEST ; Laurie J. HANNIGAN ; Alexandra HAVDAHL in Autism, 28-8 (August 2024)
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Titre : Measuring autism-associated traits in the general population: Factor structure and measurement invariance across sex and diagnosis status of the Social Communication Questionnaire Type de document : Texte imprimé et/ou numérique Auteurs : Ragna BUGGE ASKELAND, Auteur ; Stian BARBO VALAND, Auteur ; Anne-Siri ØYEN, Auteur ; Synnve SCHJØLBERG, Auteur ; Vanessa H. BAL, Auteur ; Somer L. BISHOP, Auteur ; Camilla STOLTENBERG, Auteur ; Tilmann VON SOEST, Auteur ; Laurie J. HANNIGAN, Auteur ; Alexandra HAVDAHL, Auteur Article en page(s) : p.2105-2119 Langues : Anglais (eng) Mots-clés : cohort studies factor analysis MBRN measurement invariance MoBa psychometrics statistical surveys and questionnaires Index. décimale : PER Périodiques Résumé : Autism screening questionnaires are sometimes used as a measure of "autism-associated traits" in samples drawn from the general population, even though such tools are primarily developed and designed for use in samples of children diagnosed with or being assessed for autism. Here, we explore the psychometric properties of the Social Communication Questionnaire (SCQ) current version reported at age 8 in a large population-based sample. Using data from the Norwegian Mother, Father and Child Cohort study (MoBa), we perform exploratory (N = 21,775) and confirmatory (N = 21,674) factor analyses on items and compare our results with previously suggested factor structure models of the SCQ. Furthermore, we test for measurement invariance across sex and registry-ascertained autism diagnostic status (Ndiagnosed = 636). A 5-factor model provided best fit to the data in both children with and without autism diagnoses, though with some qualitative differences in what the factors represent across these groups. This model performed largely consistently across boys and girls in the general population. Taken together, the SCQ?s measurement properties must be carefully considered when it is used in population-based samples and measurement invariance testing of other autism screening tools used in similar contexts is warranted. Lay abstract Using questionnaires in research relies on the expectation that they measure the same things across different groups of individuals. If this is not true, then interpretations of results can be misleading when researchers compare responses across different groups of individuals or use in it a group that differs from that in which the questionnaire was developed. For the questionnaire we investigated, the Social Communication Questionnaire (SCQ), we found that parents of boys and girls responded to questionnaire items in largely the same way but that the SCQ measured traits and behaviors slightly differently depending on whether the children had autism. Based on these results, we concluded that researchers using this questionnaire should carefully consider these differences when deciding how to interpret findings. SCQ scores as a reflection of "autism-associated traits" in samples that are mostly or entirely made up of individuals without an autism diagnosis may be misleading and we encourage a more precise interpretation of scores as a broader indication of social-communicative and behavioral traits. En ligne : https://dx.doi.org/10.1177/13623613231219306 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=533
in Autism > 28-8 (August 2024) . - p.2105-2119[article] Measuring autism-associated traits in the general population: Factor structure and measurement invariance across sex and diagnosis status of the Social Communication Questionnaire [Texte imprimé et/ou numérique] / Ragna BUGGE ASKELAND, Auteur ; Stian BARBO VALAND, Auteur ; Anne-Siri ØYEN, Auteur ; Synnve SCHJØLBERG, Auteur ; Vanessa H. BAL, Auteur ; Somer L. BISHOP, Auteur ; Camilla STOLTENBERG, Auteur ; Tilmann VON SOEST, Auteur ; Laurie J. HANNIGAN, Auteur ; Alexandra HAVDAHL, Auteur . - p.2105-2119.
Langues : Anglais (eng)
in Autism > 28-8 (August 2024) . - p.2105-2119
Mots-clés : cohort studies factor analysis MBRN measurement invariance MoBa psychometrics statistical surveys and questionnaires Index. décimale : PER Périodiques Résumé : Autism screening questionnaires are sometimes used as a measure of "autism-associated traits" in samples drawn from the general population, even though such tools are primarily developed and designed for use in samples of children diagnosed with or being assessed for autism. Here, we explore the psychometric properties of the Social Communication Questionnaire (SCQ) current version reported at age 8 in a large population-based sample. Using data from the Norwegian Mother, Father and Child Cohort study (MoBa), we perform exploratory (N = 21,775) and confirmatory (N = 21,674) factor analyses on items and compare our results with previously suggested factor structure models of the SCQ. Furthermore, we test for measurement invariance across sex and registry-ascertained autism diagnostic status (Ndiagnosed = 636). A 5-factor model provided best fit to the data in both children with and without autism diagnoses, though with some qualitative differences in what the factors represent across these groups. This model performed largely consistently across boys and girls in the general population. Taken together, the SCQ?s measurement properties must be carefully considered when it is used in population-based samples and measurement invariance testing of other autism screening tools used in similar contexts is warranted. Lay abstract Using questionnaires in research relies on the expectation that they measure the same things across different groups of individuals. If this is not true, then interpretations of results can be misleading when researchers compare responses across different groups of individuals or use in it a group that differs from that in which the questionnaire was developed. For the questionnaire we investigated, the Social Communication Questionnaire (SCQ), we found that parents of boys and girls responded to questionnaire items in largely the same way but that the SCQ measured traits and behaviors slightly differently depending on whether the children had autism. Based on these results, we concluded that researchers using this questionnaire should carefully consider these differences when deciding how to interpret findings. SCQ scores as a reflection of "autism-associated traits" in samples that are mostly or entirely made up of individuals without an autism diagnosis may be misleading and we encourage a more precise interpretation of scores as a broader indication of social-communicative and behavioral traits. En ligne : https://dx.doi.org/10.1177/13623613231219306 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=533 Mechanisms linking parental educational attainment with child ADHD, depression, and academic problems: a study of extended families in The Norwegian Mother, Father and Child Cohort Study / Fartein Ask TORVIK in Journal of Child Psychology and Psychiatry, 61-9 (September 2020)
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Titre : Mechanisms linking parental educational attainment with child ADHD, depression, and academic problems: a study of extended families in The Norwegian Mother, Father and Child Cohort Study Type de document : Texte imprimé et/ou numérique Auteurs : Fartein Ask TORVIK, Auteur ; Espen Moen EILERTSEN, Auteur ; Tom A. MCADAMS, Auteur ; Kristin GUSTAVSON, Auteur ; Henrik Daae ZACHRISSON, Auteur ; Ragnhild BRANDLISTUEN, Auteur ; Line C. GJERDE, Auteur ; Alexandra HAVDAHL, Auteur ; Camilla STOLTENBERG, Auteur ; Helga ASK, Auteur ; Eivind YSTROM, Auteur Article en page(s) : p.1009-1018 Langues : Anglais (eng) Mots-clés : Attention deficit hyperactivity disorder MoBa academic problems depression educational attainment Index. décimale : PER Périodiques Résumé : BACKGROUND: Low educational attainment in parents is associated with child psychopathology. It is not clear whether the associations are due to risk factors that family members share or due to effects of maternal or paternal education on the offspring. We investigate whether associations between maternal and paternal educational attainment and child symptoms of attention deficit/hyperactivity disorder (ADHD), depression, and academic problems are due to shared genetic factors, shared family environmental factors, or effects of the parental phenotype educational attainment itself. METHODS: This study is based on the Norwegian Mother, Father and Child Cohort Study (MoBa). The sample comprised 34,958 children (17,128 girls) in 28,372 extended-family units. We used data from related nuclear families linked by siblings in the parent generation. We applied a quasi-experimental extended children-of-twins design that included siblings in both generations and took account of nonrandom mating by including partners. Educational attainment was self-reported by mothers and fathers. Mothers reported children's symptoms of ADHD, symptoms of depression, and academic problems by questionnaire when the children were 8 years old. RESULTS: Children of lowly educated parents scored higher on all outcomes and had an approximate doubling of the risk of high symptom levels. The association between maternal and paternal educational attainment and child symptoms of ADHD and academic problems persisted after controlling for shared genetic and family environmental factors. Phenotypic transmission to depression was weaker and in the best fitting model fully explained by genetic factors shared by the two generations. CONCLUSIONS: Associations between educational attainment of mothers and fathers and child symptoms of ADHD and academic problems could not be ascribed to shared familial risk factors, whereas associations with symptoms of depression could. Parental education or resources and behaviors resulting from low education might be targets of interventions aimed at reducing symptoms of ADHD and academic problems. En ligne : http://dx.doi.org/10.1111/jcpp.13197 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430
in Journal of Child Psychology and Psychiatry > 61-9 (September 2020) . - p.1009-1018[article] Mechanisms linking parental educational attainment with child ADHD, depression, and academic problems: a study of extended families in The Norwegian Mother, Father and Child Cohort Study [Texte imprimé et/ou numérique] / Fartein Ask TORVIK, Auteur ; Espen Moen EILERTSEN, Auteur ; Tom A. MCADAMS, Auteur ; Kristin GUSTAVSON, Auteur ; Henrik Daae ZACHRISSON, Auteur ; Ragnhild BRANDLISTUEN, Auteur ; Line C. GJERDE, Auteur ; Alexandra HAVDAHL, Auteur ; Camilla STOLTENBERG, Auteur ; Helga ASK, Auteur ; Eivind YSTROM, Auteur . - p.1009-1018.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-9 (September 2020) . - p.1009-1018
Mots-clés : Attention deficit hyperactivity disorder MoBa academic problems depression educational attainment Index. décimale : PER Périodiques Résumé : BACKGROUND: Low educational attainment in parents is associated with child psychopathology. It is not clear whether the associations are due to risk factors that family members share or due to effects of maternal or paternal education on the offspring. We investigate whether associations between maternal and paternal educational attainment and child symptoms of attention deficit/hyperactivity disorder (ADHD), depression, and academic problems are due to shared genetic factors, shared family environmental factors, or effects of the parental phenotype educational attainment itself. METHODS: This study is based on the Norwegian Mother, Father and Child Cohort Study (MoBa). The sample comprised 34,958 children (17,128 girls) in 28,372 extended-family units. We used data from related nuclear families linked by siblings in the parent generation. We applied a quasi-experimental extended children-of-twins design that included siblings in both generations and took account of nonrandom mating by including partners. Educational attainment was self-reported by mothers and fathers. Mothers reported children's symptoms of ADHD, symptoms of depression, and academic problems by questionnaire when the children were 8 years old. RESULTS: Children of lowly educated parents scored higher on all outcomes and had an approximate doubling of the risk of high symptom levels. The association between maternal and paternal educational attainment and child symptoms of ADHD and academic problems persisted after controlling for shared genetic and family environmental factors. Phenotypic transmission to depression was weaker and in the best fitting model fully explained by genetic factors shared by the two generations. CONCLUSIONS: Associations between educational attainment of mothers and fathers and child symptoms of ADHD and academic problems could not be ascribed to shared familial risk factors, whereas associations with symptoms of depression could. Parental education or resources and behaviors resulting from low education might be targets of interventions aimed at reducing symptoms of ADHD and academic problems. En ligne : http://dx.doi.org/10.1111/jcpp.13197 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430 Adverse family life events during pregnancy and ADHD symptoms in five-year-old offspring / M. A. ROSENQVIST in Journal of Child Psychology and Psychiatry, 60-6 (June 2019)
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PermalinkMaternal perinatal and concurrent depressive symptoms and child behavior problems: a sibling comparison study / Line C. GJERDE in Journal of Child Psychology and Psychiatry, 58-7 (July 2017)
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PermalinkOn the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families / Espen M. EILERTSEN in Journal of Child Psychology and Psychiatry, 63-10 (October 2022)
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PermalinkThe Structure of Autism Spectrum Disorder Symptoms in the General Population at 18 Months / Karin T. BEUKER in Journal of Autism and Developmental Disorders, 43-1 (January 2013)
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