Altered reward system reactivity for personalized circumscribed interests in autism / G. KOHLS in Molecular Autism, 9 (2018)  

Public ISBD [article]  inMolecular Autism > 9 (2018) . - 9p. Titre : Altered reward system reactivity for personalized circumscribed interests in autism Type de document : Texte imprimé et/ou numérique Auteurs : G. KOHLS, Auteur ; Ligia ANTEZANA, Auteur ; M. G. MOSNER, Auteur ; Robert T. SCHULTZ, Auteur ; B. E. YERYS, Auteur Article en page(s) : 9p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Caudate nucleus  Circumscribed interests  Functional magnetic resonance imaging  Motivation  Restricted and repetitive behaviors and interests  Reward  Reward system  Striatum Index. décimale : PER Périodiques Résumé : Background: Neurobiological research in autism spectrum disorders (ASD) has paid little attention on brain mechanisms that cause and maintain restricted and repetitive behaviors and interests (RRBIs). Evidence indicates an imbalance in the brain's reward system responsiveness to social and non-social stimuli may contribute to both social deficits and RRBIs. Thus, this study's central aim was to compare brain responsiveness to individual RRBI (i.e., circumscribed interests), with social rewards (i.e., social approval), in youth with ASD relative to typically developing controls (TDCs). Methods: We conducted a 3T functional magnetic resonance imaging (fMRI) study to investigate the blood-oxygenation-level-dependent effect of personalized circumscribed interest rewards versus social rewards in 39 youth with ASD relative to 22 TDC. To probe the reward system, we employed short video clips as reinforcement in an instrumental incentive delay task. This optimization increased the task's ecological validity compared to still pictures that are often used in this line of research. Results: Compared to TDCs, youth with ASD had stronger reward system responses for CIs mostly within the non-social realm (e.g., video games) than social rewards (e.g., approval). Additionally, this imbalance within the caudate nucleus' responsiveness was related to greater social impairment. Conclusions: The current data support the idea of reward system dysfunction that may contribute to enhanced motivation for RRBIs in ASD, accompanied by diminished motivation for social engagement. If a dysregulated reward system indeed supports the emergence and maintenance of social and non-social symptoms of ASD, then strategically targeting the reward system in future treatment endeavors may allow for more efficacious treatment practices that help improve outcomes for individuals with ASD and their families. En ligne : http://dx.doi.org/10.1186/s13229-018-0195-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354 [article] Altered reward system reactivity for personalized circumscribed interests in autism [Texte imprimé et/ou numérique] / G. KOHLS, Auteur ; Ligia ANTEZANA, Auteur ; M. G. MOSNER, Auteur ; Robert T. SCHULTZ, Auteur ; B. E. YERYS, Auteur . - 9p. Langues : Anglais (eng) in Molecular Autism > 9 (2018) . - 9p. Mots-clés : Autism spectrum disorders  Caudate nucleus  Circumscribed interests  Functional magnetic resonance imaging  Motivation  Restricted and repetitive behaviors and interests  Reward  Reward system  Striatum Index. décimale : PER Périodiques Résumé : Background: Neurobiological research in autism spectrum disorders (ASD) has paid little attention on brain mechanisms that cause and maintain restricted and repetitive behaviors and interests (RRBIs). Evidence indicates an imbalance in the brain's reward system responsiveness to social and non-social stimuli may contribute to both social deficits and RRBIs. Thus, this study's central aim was to compare brain responsiveness to individual RRBI (i.e., circumscribed interests), with social rewards (i.e., social approval), in youth with ASD relative to typically developing controls (TDCs). Methods: We conducted a 3T functional magnetic resonance imaging (fMRI) study to investigate the blood-oxygenation-level-dependent effect of personalized circumscribed interest rewards versus social rewards in 39 youth with ASD relative to 22 TDC. To probe the reward system, we employed short video clips as reinforcement in an instrumental incentive delay task. This optimization increased the task's ecological validity compared to still pictures that are often used in this line of research. Results: Compared to TDCs, youth with ASD had stronger reward system responses for CIs mostly within the non-social realm (e.g., video games) than social rewards (e.g., approval). Additionally, this imbalance within the caudate nucleus' responsiveness was related to greater social impairment. Conclusions: The current data support the idea of reward system dysfunction that may contribute to enhanced motivation for RRBIs in ASD, accompanied by diminished motivation for social engagement. If a dysregulated reward system indeed supports the emergence and maintenance of social and non-social symptoms of ASD, then strategically targeting the reward system in future treatment endeavors may allow for more efficacious treatment practices that help improve outcomes for individuals with ASD and their families. En ligne : http://dx.doi.org/10.1186/s13229-018-0195-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354

Detecting and Classifying Self-injurious Behavior in Autism Spectrum Disorder Using Machine Learning Techniques / Kristine D. CANTIN-GARSIDE in Journal of Autism and Developmental Disorders, 50-11 (November 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.4039-4052 Titre : Detecting and Classifying Self-injurious Behavior in Autism Spectrum Disorder Using Machine Learning Techniques Type de document : Texte imprimé et/ou numérique Auteurs : Kristine D. CANTIN-GARSIDE, Auteur ; Zhenyu KONG, Auteur ; Susan W. WHITE, Auteur ; Ligia ANTEZANA, Auteur ; Sunwook KIM, Auteur ; Maury A. NUSSBAUM, Auteur Article en page(s) : p.4039-4052 Langues : Anglais (eng) Mots-clés : Activity recognition  Autism  Machine learning  Wearable sensors Index. décimale : PER Périodiques Résumé : Traditional self-injurious behavior (SIB) management can place compliance demands on the caregiver and have low ecological validity and accuracy. To support an SIB monitoring system for autism spectrum disorder (ASD), we evaluated machine learning methods for detecting and distinguishing diverse SIB types. SIB episodes were captured with body-worn accelerometers from children with ASD and SIB. The highest detection accuracy was found with k-nearest neighbors and support vector machines (up to 99.1% for individuals and 94.6% for grouped participants), and classification efficiency was quite high (offline processing at?~?0.1 ms/observation). Our results provide an initial step toward creating a continuous and objective smart SIB monitoring system, which could in turn facilitate the future care of a pervasive concern in ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04463-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Detecting and Classifying Self-injurious Behavior in Autism Spectrum Disorder Using Machine Learning Techniques [Texte imprimé et/ou numérique] / Kristine D. CANTIN-GARSIDE, Auteur ; Zhenyu KONG, Auteur ; Susan W. WHITE, Auteur ; Ligia ANTEZANA, Auteur ; Sunwook KIM, Auteur ; Maury A. NUSSBAUM, Auteur . - p.4039-4052. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-11 (November 2020) . - p.4039-4052 Mots-clés : Activity recognition  Autism  Machine learning  Wearable sensors Index. décimale : PER Périodiques Résumé : Traditional self-injurious behavior (SIB) management can place compliance demands on the caregiver and have low ecological validity and accuracy. To support an SIB monitoring system for autism spectrum disorder (ASD), we evaluated machine learning methods for detecting and distinguishing diverse SIB types. SIB episodes were captured with body-worn accelerometers from children with ASD and SIB. The highest detection accuracy was found with k-nearest neighbors and support vector machines (up to 99.1% for individuals and 94.6% for grouped participants), and classification efficiency was quite high (offline processing at?~?0.1 ms/observation). Our results provide an initial step toward creating a continuous and objective smart SIB monitoring system, which could in turn facilitate the future care of a pervasive concern in ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04463-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

Evaluation of the ADHD Rating Scale in Youth with Autism / Benjamin E. YERYS in Journal of Autism and Developmental Disorders, 47-1 (January 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.90-100 Titre : Evaluation of the ADHD Rating Scale in Youth with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Benjamin E. YERYS, Auteur ; Jenelle NISSLEY-TSIOPINIS, Auteur ; Ashley DE MARCHENA, Auteur ; Marley W. WATKINS, Auteur ; Ligia ANTEZANA, Auteur ; Thomas J. POWER, Auteur ; Robert T. SCHULTZ, Auteur Article en page(s) : p.90-100 Langues : Anglais (eng) Mots-clés : Autism  Attention deficit/hyperactivity disorder  Comorbidity  Screening  Factor analysis Index. décimale : PER Périodiques Résumé : Scientists and clinicians regularly use clinical screening tools for attention deficit/hyperactivity disorder (ADHD) to assess comorbidity without empirical evidence that these measures are valid in youth with autism spectrum disorder (ASD). We examined the prevalence of youth meeting ADHD criteria on the ADHD rating scale fourth edition (ADHD-RS-IV), the relationship of ADHD-RS-IV ratings with participant characteristics and behaviors, and its underlying factor structure in 386, 7–17 year olds with ASD without intellectual disability. Expected parent prevalence rates, relationships with age and externalizing behaviors were observed, but confirmatory factor analyses revealed unsatisfactory fits for one-, two-, three-factor models. Exploratory analyses revealed several items cross-loading on multiple factors. Implications of screening ADHD in youth with ASD using current diagnostic criteria are discussed. En ligne : http://dx.doi.org/10.1007/s10803-016-2933-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 [article] Evaluation of the ADHD Rating Scale in Youth with Autism [Texte imprimé et/ou numérique] / Benjamin E. YERYS, Auteur ; Jenelle NISSLEY-TSIOPINIS, Auteur ; Ashley DE MARCHENA, Auteur ; Marley W. WATKINS, Auteur ; Ligia ANTEZANA, Auteur ; Thomas J. POWER, Auteur ; Robert T. SCHULTZ, Auteur . - p.90-100. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.90-100 Mots-clés : Autism  Attention deficit/hyperactivity disorder  Comorbidity  Screening  Factor analysis Index. décimale : PER Périodiques Résumé : Scientists and clinicians regularly use clinical screening tools for attention deficit/hyperactivity disorder (ADHD) to assess comorbidity without empirical evidence that these measures are valid in youth with autism spectrum disorder (ASD). We examined the prevalence of youth meeting ADHD criteria on the ADHD rating scale fourth edition (ADHD-RS-IV), the relationship of ADHD-RS-IV ratings with participant characteristics and behaviors, and its underlying factor structure in 386, 7–17 year olds with ASD without intellectual disability. Expected parent prevalence rates, relationships with age and externalizing behaviors were observed, but confirmatory factor analyses revealed unsatisfactory fits for one-, two-, three-factor models. Exploratory analyses revealed several items cross-loading on multiple factors. Implications of screening ADHD in youth with ASD using current diagnostic criteria are discussed. En ligne : http://dx.doi.org/10.1007/s10803-016-2933-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

Gender differences in restricted and repetitive behaviors and interests in youth with autism / Ligia ANTEZANA in Autism Research, 12-2 (February 2019)  

Public ISBD [article]  inAutism Research > 12-2 (February 2019) . - p.274-283 Titre : Gender differences in restricted and repetitive behaviors and interests in youth with autism Type de document : Texte imprimé et/ou numérique Auteurs : Ligia ANTEZANA, Auteur ; R. S. FACTOR, Auteur ; E. E. CONDY, Auteur ; M. V. STREGE, Auteur ; A. SCARPA, Auteur ; J. A. RICHEY, Auteur Article en page(s) : p.274-283 Langues : Anglais (eng) Mots-clés : gender/female ASD  restricted/repetitive behavior  sex differences Index. décimale : PER Périodiques Résumé : Previous work has found gender differences in restricted and repetitive behaviors and interests (RRBI) for autism spectrum disorder (ASD). Compared to girls, affected boys have increased stereotyped and restricted behaviors; however much less is known about gender differences in other areas of RRBI. This study aims to identify whether specific RRBI (i.e., stereotyped, self-injurious, compulsive, insistence on sameness, ritualistic, and restricted), as measured by item-level data on the Repetitive Behavior Scale-Revised (RBS-R), can distinguish girls from boys with ASD. Participants included 615 individuals with ASD (507 boys; 82.4%), ages 3-18 years of age (M = 10.26, SD = 4.20), who agreed to share data with the National Database for Autism Research (NDAR). Multivariate analysis of variance and discriminant function analysis (DFA) were used to determine whether item-level RBS-R data could correctly classify cases by gender. DFA results suggest that RBS-R items significantly differentiate gender. Strongly differentiating RBS-R items had greater success in correctly classifying affected boys (67.90%) than girls (61.00%). Items that best-discriminated gender were heightened stereotyped behaviors and restricted interests items in boys and compulsive, sameness, restricted, and self-injurious behavior items in girls. This study is the first to find that girls with ASD may have increased compulsive, sameness, and restricted RRBI compared to boys. Additionally, findings support heightened self-injurious behaviors in affected girls. Future research should disentangle whether elevated rates of RRBI in girls are central to the presentation of ASD in girls or an epiphenomenon of the high rates of co-occurring disorders (e.g., anxiety) noted in girls. Autism Res 2019, 12: 274-283 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study is the first to examine a comprehensive measure of repetitive behavior in children with autism, with findings of increased compulsive, insistence on sameness, and self-injurious behavior characterizing girls and increased stereotyped and restricted behavior characterizing boys. Future research should determine whether these elevated behaviors in girls are directly part of the autism presentation in girls or symptoms of co-occurring psychopathology. It is important for autism diagnostic measures to best capture the types of repetitive behavior girls may demonstrate. En ligne : http://dx.doi.org/10.1002/aur.2049 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383 [article] Gender differences in restricted and repetitive behaviors and interests in youth with autism [Texte imprimé et/ou numérique] / Ligia ANTEZANA, Auteur ; R. S. FACTOR, Auteur ; E. E. CONDY, Auteur ; M. V. STREGE, Auteur ; A. SCARPA, Auteur ; J. A. RICHEY, Auteur . - p.274-283. Langues : Anglais (eng) in Autism Research > 12-2 (February 2019) . - p.274-283 Mots-clés : gender/female ASD  restricted/repetitive behavior  sex differences Index. décimale : PER Périodiques Résumé : Previous work has found gender differences in restricted and repetitive behaviors and interests (RRBI) for autism spectrum disorder (ASD). Compared to girls, affected boys have increased stereotyped and restricted behaviors; however much less is known about gender differences in other areas of RRBI. This study aims to identify whether specific RRBI (i.e., stereotyped, self-injurious, compulsive, insistence on sameness, ritualistic, and restricted), as measured by item-level data on the Repetitive Behavior Scale-Revised (RBS-R), can distinguish girls from boys with ASD. Participants included 615 individuals with ASD (507 boys; 82.4%), ages 3-18 years of age (M = 10.26, SD = 4.20), who agreed to share data with the National Database for Autism Research (NDAR). Multivariate analysis of variance and discriminant function analysis (DFA) were used to determine whether item-level RBS-R data could correctly classify cases by gender. DFA results suggest that RBS-R items significantly differentiate gender. Strongly differentiating RBS-R items had greater success in correctly classifying affected boys (67.90%) than girls (61.00%). Items that best-discriminated gender were heightened stereotyped behaviors and restricted interests items in boys and compulsive, sameness, restricted, and self-injurious behavior items in girls. This study is the first to find that girls with ASD may have increased compulsive, sameness, and restricted RRBI compared to boys. Additionally, findings support heightened self-injurious behaviors in affected girls. Future research should disentangle whether elevated rates of RRBI in girls are central to the presentation of ASD in girls or an epiphenomenon of the high rates of co-occurring disorders (e.g., anxiety) noted in girls. Autism Res 2019, 12: 274-283 (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study is the first to examine a comprehensive measure of repetitive behavior in children with autism, with findings of increased compulsive, insistence on sameness, and self-injurious behavior characterizing girls and increased stereotyped and restricted behavior characterizing boys. Future research should determine whether these elevated behaviors in girls are directly part of the autism presentation in girls or symptoms of co-occurring psychopathology. It is important for autism diagnostic measures to best capture the types of repetitive behavior girls may demonstrate. En ligne : http://dx.doi.org/10.1002/aur.2049 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383

Integrating Measurement-Based Care into Treatment for Autism Spectrum Disorder: Insights from a Community Clinic / T. C. MCFAYDEN in Journal of Autism and Developmental Disorders, 51-10 (October 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3651-3661 Titre : Integrating Measurement-Based Care into Treatment for Autism Spectrum Disorder: Insights from a Community Clinic Type de document : Texte imprimé et/ou numérique Auteurs : T. C. MCFAYDEN, Auteur ; A. J. GATTO, Auteur ; A. V. DAHIYA, Auteur ; Ligia ANTEZANA, Auteur ; Y. MIYAZAKI, Auteur ; L. D. COOPER, Auteur Article en page(s) : p.3651-3661 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/therapy  Autistic Disorder  Humans  Problem Solving  Autism spectrum disorder  Community clinic  Evidence-based practice  Hierarchical linear modeling  Measurement-based care Index. décimale : PER Périodiques Résumé : Measurement-based care (MBC), an evidence-based approach that has demonstrated efficacy for improving treatment outcomes, has yet to be investigated in clients with Autism Spectrum Disorder. The current paper investigates the use of MBC in autistic (n?=?20) and non-autistic (n?=?20) clients matched on age, sex, and presenting problem. Results of change score analysis indicated that utilizing routine symptom monitoring can enhance treatment evaluation. Autistic clients participated in significantly more sessions, made significantly less progress, and were less compliant with MBC than non-autistic clients. Though hierarchical linear modeling demonstrated no significant differences in treatment slope, results indicated moderate effect size. These results inform the use of MBC in community clinics, highlighting policy implications and need for targeted measurement. En ligne : http://dx.doi.org/10.1007/s10803-020-04824-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] Integrating Measurement-Based Care into Treatment for Autism Spectrum Disorder: Insights from a Community Clinic [Texte imprimé et/ou numérique] / T. C. MCFAYDEN, Auteur ; A. J. GATTO, Auteur ; A. V. DAHIYA, Auteur ; Ligia ANTEZANA, Auteur ; Y. MIYAZAKI, Auteur ; L. D. COOPER, Auteur . - p.3651-3661. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3651-3661 Mots-clés : Autism Spectrum Disorder/diagnosis/therapy  Autistic Disorder  Humans  Problem Solving  Autism spectrum disorder  Community clinic  Evidence-based practice  Hierarchical linear modeling  Measurement-based care Index. décimale : PER Périodiques Résumé : Measurement-based care (MBC), an evidence-based approach that has demonstrated efficacy for improving treatment outcomes, has yet to be investigated in clients with Autism Spectrum Disorder. The current paper investigates the use of MBC in autistic (n?=?20) and non-autistic (n?=?20) clients matched on age, sex, and presenting problem. Results of change score analysis indicated that utilizing routine symptom monitoring can enhance treatment evaluation. Autistic clients participated in significantly more sessions, made significantly less progress, and were less compliant with MBC than non-autistic clients. Though hierarchical linear modeling demonstrated no significant differences in treatment slope, results indicated moderate effect size. These results inform the use of MBC in community clinics, highlighting policy implications and need for targeted measurement. En ligne : http://dx.doi.org/10.1007/s10803-020-04824-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

Neural Correlates of Set-Shifting in Children With Autism / Benjamin E. YERYS in Autism Research, 8-4 (August 2015)  

Permalink

A Preliminary Psychometric Analysis of the Difficulties with Emotion Regulation Scale (DERS) Among Autistic Adolescents and Adults: Factor Structure, Reliability, and Validity / A. J. MCVEY in Journal of Autism and Developmental Disorders, 52-3 (March 2022)  

Permalink

Social analogical reasoning in school-aged children with autism spectrum disorder and typically developing peers / Adam E. GREEN in Autism, 21-4 (May 2017)  

Permalink

Social-Emotional Inhibition of Return in Children with Autism Spectrum Disorder Versus Typical Development / Ligia ANTEZANA in Journal of Autism and Developmental Disorders, 46-4 (April 2016)  

Permalink

---

1 (1 - 9 / 9)