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Résultat de la recherche
11 recherche sur le mot-clé 'Striatum'




Children with ADHD symptoms show decreased activity in ventral striatum during the anticipation of reward, irrespective of ADHD diagnosis / Branko M. VAN HULST in Journal of Child Psychology and Psychiatry, 58-2 (February 2017)
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Titre : Children with ADHD symptoms show decreased activity in ventral striatum during the anticipation of reward, irrespective of ADHD diagnosis Type de document : Texte imprimé et/ou numérique Auteurs : Branko M. VAN HULST, Auteur ; Patrick DE ZEEUW, Auteur ; Dienke J. BOS, Auteur ; Yvonne RIJKS, Auteur ; Sebastiaan F. W. NEGGERS, Auteur ; Sarah DURSTON, Auteur Année de publication : 2017 Article en page(s) : p.206-214 Langues : Anglais (eng) Mots-clés : Attention-deficit/hyperactivity disorder fMRI reward processing striatum trans-diagnostic mechanisms reward anticipation autism spectrum disorder Index. décimale : PER Périodiques Résumé : Background Changes in reward processing are thought to be involved in the etiology of attention-deficit/hyperactivity disorder (ADHD), as well as other developmental disorders. In addition, different forms of therapy for ADHD rely on reinforcement principles. As such, improved understanding of reward processing in ADHD could eventually lead to more effective treatment options. However, differences in reward processing may not be specific to ADHD, but may be a trans-diagnostic feature of disorders that involve ADHD-like symptoms. Methods In this event-related fMRI study, we used a child-friendly version of the monetary incentive delay task to assess performance and brain activity during reward anticipation. Also, we collected questionnaire data to assess reward sensitivity in daily life. For final analyses, data were available for 27 typically developing children, 24 children with ADHD, and 25 children with an autism spectrum disorder (ASD) and ADHD symptoms. Results We found decreased activity in ventral striatum during anticipation of reward in children with ADHD symptoms, both for children with ADHD as their primary diagnosis and in children with autism spectrum disorder and ADHD symptoms. We found that higher parent-rated sensitivity to reward was associated with greater anticipatory activity in ventral striatum for children with ADHD symptoms. In contrast, there was no relationship between the degree of ADHD symptoms and activity in ventral striatum. Conclusions We provide evidence of biological and behavioral differences in reward sensitivity in children with ADHD symptoms, regardless of their primary diagnosis. Ultimately, a dimensional brain-behavior model of reward sensitivity in children with symptoms of ADHD may be useful to refine treatment options dependent on reward processing. En ligne : http://dx.doi.org/10.1111/jcpp.12643 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=299
in Journal of Child Psychology and Psychiatry > 58-2 (February 2017) . - p.206-214[article] Children with ADHD symptoms show decreased activity in ventral striatum during the anticipation of reward, irrespective of ADHD diagnosis [Texte imprimé et/ou numérique] / Branko M. VAN HULST, Auteur ; Patrick DE ZEEUW, Auteur ; Dienke J. BOS, Auteur ; Yvonne RIJKS, Auteur ; Sebastiaan F. W. NEGGERS, Auteur ; Sarah DURSTON, Auteur . - 2017 . - p.206-214.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-2 (February 2017) . - p.206-214
Mots-clés : Attention-deficit/hyperactivity disorder fMRI reward processing striatum trans-diagnostic mechanisms reward anticipation autism spectrum disorder Index. décimale : PER Périodiques Résumé : Background Changes in reward processing are thought to be involved in the etiology of attention-deficit/hyperactivity disorder (ADHD), as well as other developmental disorders. In addition, different forms of therapy for ADHD rely on reinforcement principles. As such, improved understanding of reward processing in ADHD could eventually lead to more effective treatment options. However, differences in reward processing may not be specific to ADHD, but may be a trans-diagnostic feature of disorders that involve ADHD-like symptoms. Methods In this event-related fMRI study, we used a child-friendly version of the monetary incentive delay task to assess performance and brain activity during reward anticipation. Also, we collected questionnaire data to assess reward sensitivity in daily life. For final analyses, data were available for 27 typically developing children, 24 children with ADHD, and 25 children with an autism spectrum disorder (ASD) and ADHD symptoms. Results We found decreased activity in ventral striatum during anticipation of reward in children with ADHD symptoms, both for children with ADHD as their primary diagnosis and in children with autism spectrum disorder and ADHD symptoms. We found that higher parent-rated sensitivity to reward was associated with greater anticipatory activity in ventral striatum for children with ADHD symptoms. In contrast, there was no relationship between the degree of ADHD symptoms and activity in ventral striatum. Conclusions We provide evidence of biological and behavioral differences in reward sensitivity in children with ADHD symptoms, regardless of their primary diagnosis. Ultimately, a dimensional brain-behavior model of reward sensitivity in children with symptoms of ADHD may be useful to refine treatment options dependent on reward processing. En ligne : http://dx.doi.org/10.1111/jcpp.12643 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=299 A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum / Taesun YOO in Molecular Autism, 11 (2020)
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Titre : A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum Type de document : Texte imprimé et/ou numérique Auteurs : Taesun YOO, Auteur ; Sun-Gyun KIM, Auteur ; Soo Hyun YANG, Auteur ; Hyun KIM, Auteur ; Eunjoon KIM, Auteur ; Soo Young KIM, Auteur Article en page(s) : 19 p. Langues : Anglais (eng) Mots-clés : Autism Locomotion psd-93 Self-grooming Social interaction Spiny projection Neurons Striatum Index. décimale : PER Périodiques Résumé : BACKGROUND: DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface receptors and signaling molecules. A recent study has demonstrated that mutations in the DLG2 promoter region are significantly associated with autism spectrum disorder (ASD). Although DLG2 is well known as a schizophrenia-susceptibility gene, the mechanisms that link DLG2 gene disruption with ASD-like behaviors remain unclear. METHODS: Mice lacking exon 14 of the Dlg2 gene (Dlg2(-/-) mice) were used to investigate whether Dlg2 deletion leads to ASD-like behavioral abnormalities. To this end, we performed a battery of behavioral tests assessing locomotion, anxiety, sociability, and repetitive behaviors. In situ hybridization was performed to determine expression levels of Dlg2 mRNA in different mouse brain regions during embryonic and postnatal brain development. We also measured excitatory and inhibitory synaptic currents to determine the impacts of Dlg2 deletion on synaptic transmission in the dorsolateral striatum. RESULTS: Dlg2(-/-) mice showed hypoactivity in a novel environment. They also exhibited decreased social approach, but normal social novelty recognition, compared with wild-type animals. In addition, Dlg2(-/-) mice displayed strong self-grooming, both in home cages and novel environments. Dlg2 mRNA levels in the striatum were heightened until postnatal day 7 in mice, implying potential roles of DLG2 in the development of striatal connectivity. In addition, the frequency of excitatory, but not inhibitory, spontaneous postsynaptic currents in the Dlg2(-/-) dorsolateral striatum was significantly reduced. CONCLUSION: These results suggest that homozygous Dlg2 deletion in mice leads to ASD-like behavioral phenotypes, including social deficits and increased repetitive behaviors, as well as reductions in excitatory synaptic input onto dorsolateral spiny projection neurons, implying that the dorsal striatum is one of the brain regions vulnerable to the developmental dysregulation of DLG2. En ligne : http://dx.doi.org/10.1186/s13229-020-00324-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427
in Molecular Autism > 11 (2020) . - 19 p.[article] A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum [Texte imprimé et/ou numérique] / Taesun YOO, Auteur ; Sun-Gyun KIM, Auteur ; Soo Hyun YANG, Auteur ; Hyun KIM, Auteur ; Eunjoon KIM, Auteur ; Soo Young KIM, Auteur . - 19 p.
Langues : Anglais (eng)
in Molecular Autism > 11 (2020) . - 19 p.
Mots-clés : Autism Locomotion psd-93 Self-grooming Social interaction Spiny projection Neurons Striatum Index. décimale : PER Périodiques Résumé : BACKGROUND: DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface receptors and signaling molecules. A recent study has demonstrated that mutations in the DLG2 promoter region are significantly associated with autism spectrum disorder (ASD). Although DLG2 is well known as a schizophrenia-susceptibility gene, the mechanisms that link DLG2 gene disruption with ASD-like behaviors remain unclear. METHODS: Mice lacking exon 14 of the Dlg2 gene (Dlg2(-/-) mice) were used to investigate whether Dlg2 deletion leads to ASD-like behavioral abnormalities. To this end, we performed a battery of behavioral tests assessing locomotion, anxiety, sociability, and repetitive behaviors. In situ hybridization was performed to determine expression levels of Dlg2 mRNA in different mouse brain regions during embryonic and postnatal brain development. We also measured excitatory and inhibitory synaptic currents to determine the impacts of Dlg2 deletion on synaptic transmission in the dorsolateral striatum. RESULTS: Dlg2(-/-) mice showed hypoactivity in a novel environment. They also exhibited decreased social approach, but normal social novelty recognition, compared with wild-type animals. In addition, Dlg2(-/-) mice displayed strong self-grooming, both in home cages and novel environments. Dlg2 mRNA levels in the striatum were heightened until postnatal day 7 in mice, implying potential roles of DLG2 in the development of striatal connectivity. In addition, the frequency of excitatory, but not inhibitory, spontaneous postsynaptic currents in the Dlg2(-/-) dorsolateral striatum was significantly reduced. CONCLUSION: These results suggest that homozygous Dlg2 deletion in mice leads to ASD-like behavioral phenotypes, including social deficits and increased repetitive behaviors, as well as reductions in excitatory synaptic input onto dorsolateral spiny projection neurons, implying that the dorsal striatum is one of the brain regions vulnerable to the developmental dysregulation of DLG2. En ligne : http://dx.doi.org/10.1186/s13229-020-00324-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427 Annual Research Review: The neurobehavioral development of multiple memory systems – implications for childhood and adolescent psychiatric disorders / Jarid GOODMAN in Journal of Child Psychology and Psychiatry, 55-6 (June 2014)
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Titre : Annual Research Review: The neurobehavioral development of multiple memory systems – implications for childhood and adolescent psychiatric disorders Type de document : Texte imprimé et/ou numérique Auteurs : Jarid GOODMAN, Auteur ; Rachel MARSH, Auteur ; Bradley S. PETERSON, Auteur ; Mark G. PACKARD, Auteur Année de publication : 2014 Article en page(s) : p.582-610 Langues : Anglais (eng) Mots-clés : Learning memory neuropsychiatry psychopathologies hippocampus striatum basal ganglia anxiety stress Index. décimale : PER Périodiques Résumé : Extensive evidence indicates that mammalian memory is organized into multiple brains systems, including a ‘cognitive’ memory system that depends on the hippocampus and a stimulus-response ‘habit’ memory system that depends on the dorsolateral striatum. Dorsal striatal-dependent habit memory may in part influence the development and expression of some human psychopathologies, particularly those characterized by strong habit-like behavioral features. The present review considers this hypothesis as it pertains to psychopathologies that typically emerge during childhood and adolescence. These disorders include Tourette syndrome, attention-deficit/hyperactivity disorder, obsessive–compulsive disorder, eating disorders, and autism spectrum disorders. Human and nonhuman animal research shows that the typical development of memory systems comprises the early maturation of striatal-dependent habit memory and the relatively late maturation of hippocampal-dependent cognitive memory. We speculate that the differing rates of development of these memory systems may in part contribute to the early emergence of habit-like symptoms in childhood and adolescence. In addition, abnormalities in hippocampal and striatal brain regions have been observed consistently in youth with these disorders, suggesting that the aberrant development of memory systems may also contribute to the emergence of habit-like symptoms as core pathological features of these illnesses. Considering these disorders within the context of multiple memory systems may help elucidate the pathogenesis of habit-like symptoms in childhood and adolescence, and lead to novel treatments that lessen the habit-like behavioral features of these disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12169 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=234
in Journal of Child Psychology and Psychiatry > 55-6 (June 2014) . - p.582-610[article] Annual Research Review: The neurobehavioral development of multiple memory systems – implications for childhood and adolescent psychiatric disorders [Texte imprimé et/ou numérique] / Jarid GOODMAN, Auteur ; Rachel MARSH, Auteur ; Bradley S. PETERSON, Auteur ; Mark G. PACKARD, Auteur . - 2014 . - p.582-610.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-6 (June 2014) . - p.582-610
Mots-clés : Learning memory neuropsychiatry psychopathologies hippocampus striatum basal ganglia anxiety stress Index. décimale : PER Périodiques Résumé : Extensive evidence indicates that mammalian memory is organized into multiple brains systems, including a ‘cognitive’ memory system that depends on the hippocampus and a stimulus-response ‘habit’ memory system that depends on the dorsolateral striatum. Dorsal striatal-dependent habit memory may in part influence the development and expression of some human psychopathologies, particularly those characterized by strong habit-like behavioral features. The present review considers this hypothesis as it pertains to psychopathologies that typically emerge during childhood and adolescence. These disorders include Tourette syndrome, attention-deficit/hyperactivity disorder, obsessive–compulsive disorder, eating disorders, and autism spectrum disorders. Human and nonhuman animal research shows that the typical development of memory systems comprises the early maturation of striatal-dependent habit memory and the relatively late maturation of hippocampal-dependent cognitive memory. We speculate that the differing rates of development of these memory systems may in part contribute to the early emergence of habit-like symptoms in childhood and adolescence. In addition, abnormalities in hippocampal and striatal brain regions have been observed consistently in youth with these disorders, suggesting that the aberrant development of memory systems may also contribute to the emergence of habit-like symptoms as core pathological features of these illnesses. Considering these disorders within the context of multiple memory systems may help elucidate the pathogenesis of habit-like symptoms in childhood and adolescence, and lead to novel treatments that lessen the habit-like behavioral features of these disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12169 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=234 Hippocampus specific iron deficiency alters competition and cooperation between developing memory systems / E. S. CARLSON in Journal of Neurodevelopmental Disorders, 2-3 (September 2010)
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Titre : Hippocampus specific iron deficiency alters competition and cooperation between developing memory systems Type de document : Texte imprimé et/ou numérique Auteurs : E. S. CARLSON, Auteur ; S. J. FRETHAM, Auteur ; E. UNGER, Auteur ; M. O'CONNOR, Auteur ; A. PETRYK, Auteur ; T. SCHALLERT, Auteur ; R. RAO, Auteur ; I. TKAC, Auteur ; Michael K. GEORGIEFF, Auteur Article en page(s) : p.133-43 Langues : Anglais (eng) Mots-clés : DMT1, Slc11a2, Nuclear magnetic resonance spectroscopy Hippocampus Iron deficiency Memory systems Morris water maze Procedural memory Spatial memory Striatum Index. décimale : PER Périodiques Résumé : UNLABELLED: Iron deficiency (ID) is the most common gestational micronutrient deficiency in the world, targets the fetal hippocampus and striatum and results in long-term behavioral abnormalities. These structures primarily mediate spatial and procedural memory, respectively, in the rodent but have interconnections that result in competition or cooperation during cognitive tasks. We determined whether ID-induced impairment of one alters the function of the other by genetically inducing a 40% reduction of hippocampus iron content in late fetal life in mice and measuring dorsal striatal gene expression and metabolism and the behavioral balance between the two memory systems in adulthood. Slc11a2(hipp/hipp) mice had similar striatum iron content, but 18% lower glucose and 44% lower lactate levels, a 30% higher phosphocreatine:creatine ratio, and reduced iron transporter gene expression compared to wild type (WT) littermates, implying reduced striatal metabolic function. Slc11a2(hipp/hipp) mice had longer mean escape times on a cued task paradigm implying impaired procedural memory. Nevertheless, when hippocampal and striatal memory systems were placed in competition using a Morris Water Maze task that alternates spatial navigation and visual cued responses during training, and forces a choice between hippocampal and striatal strategies during probe trials, Slc11a2(hipp/hipp) mice used the hippocampus-dependent response less often (25%) and the visual cued response more often (75%) compared to WT littermates that used both strategies approximately equally. Hippocampal ID not only reduces spatial recognition memory performance but also affects systems that support procedural memory, suggesting an altered balance between memory systems. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s11689-010-9049-0) contains supplementary material, which is available to authorized users. En ligne : http://dx.doi.org/10.1007/s11689-010-9049-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=342
in Journal of Neurodevelopmental Disorders > 2-3 (September 2010) . - p.133-43[article] Hippocampus specific iron deficiency alters competition and cooperation between developing memory systems [Texte imprimé et/ou numérique] / E. S. CARLSON, Auteur ; S. J. FRETHAM, Auteur ; E. UNGER, Auteur ; M. O'CONNOR, Auteur ; A. PETRYK, Auteur ; T. SCHALLERT, Auteur ; R. RAO, Auteur ; I. TKAC, Auteur ; Michael K. GEORGIEFF, Auteur . - p.133-43.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 2-3 (September 2010) . - p.133-43
Mots-clés : DMT1, Slc11a2, Nuclear magnetic resonance spectroscopy Hippocampus Iron deficiency Memory systems Morris water maze Procedural memory Spatial memory Striatum Index. décimale : PER Périodiques Résumé : UNLABELLED: Iron deficiency (ID) is the most common gestational micronutrient deficiency in the world, targets the fetal hippocampus and striatum and results in long-term behavioral abnormalities. These structures primarily mediate spatial and procedural memory, respectively, in the rodent but have interconnections that result in competition or cooperation during cognitive tasks. We determined whether ID-induced impairment of one alters the function of the other by genetically inducing a 40% reduction of hippocampus iron content in late fetal life in mice and measuring dorsal striatal gene expression and metabolism and the behavioral balance between the two memory systems in adulthood. Slc11a2(hipp/hipp) mice had similar striatum iron content, but 18% lower glucose and 44% lower lactate levels, a 30% higher phosphocreatine:creatine ratio, and reduced iron transporter gene expression compared to wild type (WT) littermates, implying reduced striatal metabolic function. Slc11a2(hipp/hipp) mice had longer mean escape times on a cued task paradigm implying impaired procedural memory. Nevertheless, when hippocampal and striatal memory systems were placed in competition using a Morris Water Maze task that alternates spatial navigation and visual cued responses during training, and forces a choice between hippocampal and striatal strategies during probe trials, Slc11a2(hipp/hipp) mice used the hippocampus-dependent response less often (25%) and the visual cued response more often (75%) compared to WT littermates that used both strategies approximately equally. Hippocampal ID not only reduces spatial recognition memory performance but also affects systems that support procedural memory, suggesting an altered balance between memory systems. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s11689-010-9049-0) contains supplementary material, which is available to authorized users. En ligne : http://dx.doi.org/10.1007/s11689-010-9049-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=342 Internalizing–externalizing comorbidity and regional brain volumes in the ABCD study / Elana SCHETTINI in Development and Psychopathology, 33-5 (December 2021)
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Titre : Internalizing–externalizing comorbidity and regional brain volumes in the ABCD study Type de document : Texte imprimé et/ou numérique Auteurs : Elana SCHETTINI, Auteur ; Sylia WILSON, Auteur ; Theodore P. BEAUCHAINE, Auteur Article en page(s) : p.1620-1633 Langues : Anglais (eng) Mots-clés : amygdala anterior cingulate RDoC heterotypic comorbidity striatum Index. décimale : PER Périodiques Résumé : Despite nonoverlapping diagnostic criteria, internalizing and externalizing disorders show substantial comorbidity. This comorbidity is attributable, at least in part, to transdiagnostic neuroaffective mechanisms. Both unipolar depression and externalizing disorders are characterized by structural and functional compromises in the striatum and its projections to the anterior cingulate cortex (ACC) and other frontal regions. Smaller volumes and dampened reward responding in these regions are associated with anhedonia and irritability – mood states that cut across the internalizing and externalizing spectra. In contrast, smaller amygdala volumes and dampened amygdala function differentiate externalizing disorders from internalizing disorders. Little is known, however, about associations between internalizing–externalizing comorbidity and brain volumes in these regions, or whether such patterns differ by sex. Using a transdiagnostic, research domain criteria (RDoC)-informed approach, we evaluate associations between heterotypic (Internalizing × Externalizing) symptom interactions and striatal, amygdalar, and ACC volumes among participants in the Adolescent Brain Cognitive Development study (N = 6,971, mean age 9.9 years, 51.6% female). Heterotypic symptoms were associated with ACC volumes for both sexes, over and above the main effects of internalizing and externalizing alone. However, heterotypic comorbidity was associated with larger ACC volumes for girls, but with smaller ACC volumes for boys. These findings suggest a need for further studies and transdiagnostic assessment by sex. En ligne : http://dx.doi.org/10.1017/S0954579421000560 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457
in Development and Psychopathology > 33-5 (December 2021) . - p.1620-1633[article] Internalizing–externalizing comorbidity and regional brain volumes in the ABCD study [Texte imprimé et/ou numérique] / Elana SCHETTINI, Auteur ; Sylia WILSON, Auteur ; Theodore P. BEAUCHAINE, Auteur . - p.1620-1633.
Langues : Anglais (eng)
in Development and Psychopathology > 33-5 (December 2021) . - p.1620-1633
Mots-clés : amygdala anterior cingulate RDoC heterotypic comorbidity striatum Index. décimale : PER Périodiques Résumé : Despite nonoverlapping diagnostic criteria, internalizing and externalizing disorders show substantial comorbidity. This comorbidity is attributable, at least in part, to transdiagnostic neuroaffective mechanisms. Both unipolar depression and externalizing disorders are characterized by structural and functional compromises in the striatum and its projections to the anterior cingulate cortex (ACC) and other frontal regions. Smaller volumes and dampened reward responding in these regions are associated with anhedonia and irritability – mood states that cut across the internalizing and externalizing spectra. In contrast, smaller amygdala volumes and dampened amygdala function differentiate externalizing disorders from internalizing disorders. Little is known, however, about associations between internalizing–externalizing comorbidity and brain volumes in these regions, or whether such patterns differ by sex. Using a transdiagnostic, research domain criteria (RDoC)-informed approach, we evaluate associations between heterotypic (Internalizing × Externalizing) symptom interactions and striatal, amygdalar, and ACC volumes among participants in the Adolescent Brain Cognitive Development study (N = 6,971, mean age 9.9 years, 51.6% female). Heterotypic symptoms were associated with ACC volumes for both sexes, over and above the main effects of internalizing and externalizing alone. However, heterotypic comorbidity was associated with larger ACC volumes for girls, but with smaller ACC volumes for boys. These findings suggest a need for further studies and transdiagnostic assessment by sex. En ligne : http://dx.doi.org/10.1017/S0954579421000560 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 Modulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin / C. M. PRETZSCH in Molecular Autism, 12 (2021)
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PermalinkSocial and monetary reward processing in autism spectrum disorders / Sonja DELMONTE in Molecular Autism, (September 2012)
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PermalinkAberrant local striatal functional connectivity in attention-deficit/hyperactivity disorder / Daniel VON RHEIN in Journal of Child Psychology and Psychiatry, 57-6 (June 2016)
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PermalinkAcamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety / T. L. SCHAEFER in Journal of Neurodevelopmental Disorders, 9-1 (December 2017)
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PermalinkAltered reward system reactivity for personalized circumscribed interests in autism / G. KOHLS in Molecular Autism, 9 (2018)
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