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Auteur David H. SKUSE |
Documents disponibles écrits par cet auteur (20)
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Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents / William P.L. MANDY in Journal of Autism and Developmental Disorders, 42-7 (July 2012)
[article]
Titre : Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur Année de publication : 2012 Article en page(s) : p.1304-1313 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Pervasive developmental disorder Sex differences High-functioning Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313[article] Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents [Texte imprimé et/ou numérique] / William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur . - 2012 . - p.1304-1313.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313
Mots-clés : Autism spectrum disorder Pervasive developmental disorder Sex differences High-functioning Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165 Short Normal Children and Environmental Disadvantage: A Longitudinal Study of Growth and Cognitive Development from 4 to 11 Years / Linda DOWDNEY in Journal of Child Psychology and Psychiatry, 39-7 (October 1998)
[article]
Titre : Short Normal Children and Environmental Disadvantage: A Longitudinal Study of Growth and Cognitive Development from 4 to 11 Years Type de document : Texte imprimé et/ou numérique Auteurs : Linda DOWDNEY, Auteur ; David H. SKUSE, Auteur ; Kathleen MORRIS, Auteur ; Andrew PICKLES, Auteur Année de publication : 1998 Article en page(s) : p.1017-1029 Langues : Anglais (eng) Mots-clés : Short-normal child intelligence longitudinal growth social deprivation reading special education school children preschool children infancy Index. décimale : PER Périodiques Résumé : The aim of this investigation was to follow up a sample of exceptionally short but medically healthy children, and a normal comparison group, previously studied at 4 years of age. They lived in an inner-city area which was, on objective criteria, seriously disadvantaged in socioeconomic terms. When first seen at 4 years, cases were significantly impaired in cognitive abilities relative to comparisons, although firstborns were much less severely affected. Of the original 46 cases, 45 were assessed again at 11 years. Most continued to live in the same geographical area. Case children remained exceptionally short, even when parental stature was taken into account, although a degree of catch-up had occurred. One third had special educational needs, and a similar proportion had been referred for speech therapy. Verbal and nonverbal cognitive skills of both case and comparison children had, on the whole, changed little and group differences persisted. In conclusion, short normal children from socioeconomically disadvantaged backgrounds are at high risk of educational failure at elementary school. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=123
in Journal of Child Psychology and Psychiatry > 39-7 (October 1998) . - p.1017-1029[article] Short Normal Children and Environmental Disadvantage: A Longitudinal Study of Growth and Cognitive Development from 4 to 11 Years [Texte imprimé et/ou numérique] / Linda DOWDNEY, Auteur ; David H. SKUSE, Auteur ; Kathleen MORRIS, Auteur ; Andrew PICKLES, Auteur . - 1998 . - p.1017-1029.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 39-7 (October 1998) . - p.1017-1029
Mots-clés : Short-normal child intelligence longitudinal growth social deprivation reading special education school children preschool children infancy Index. décimale : PER Périodiques Résumé : The aim of this investigation was to follow up a sample of exceptionally short but medically healthy children, and a normal comparison group, previously studied at 4 years of age. They lived in an inner-city area which was, on objective criteria, seriously disadvantaged in socioeconomic terms. When first seen at 4 years, cases were significantly impaired in cognitive abilities relative to comparisons, although firstborns were much less severely affected. Of the original 46 cases, 45 were assessed again at 11 years. Most continued to live in the same geographical area. Case children remained exceptionally short, even when parental stature was taken into account, although a degree of catch-up had occurred. One third had special educational needs, and a similar proportion had been referred for speech therapy. Verbal and nonverbal cognitive skills of both case and comparison children had, on the whole, changed little and group differences persisted. In conclusion, short normal children from socioeconomically disadvantaged backgrounds are at high risk of educational failure at elementary school. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=123 The Developmental Sequelae of Nonorganic Failure to Thrive / Janet BODDY in Journal of Child Psychology and Psychiatry, 41-8 (November 2000)
[article]
Titre : The Developmental Sequelae of Nonorganic Failure to Thrive Type de document : Texte imprimé et/ou numérique Auteurs : Janet BODDY, Auteur ; David H. SKUSE, Auteur ; Bernice ANDREWS, Auteur Année de publication : 2000 Article en page(s) : p.1003-1014 Langues : Anglais (eng) Mots-clés : Child development failure to thrive follow-up studies growth retardation longitudinal studies school children Index. décimale : PER Périodiques Résumé : The developmental sequelae of infant failure to thrive (FTT) were examined in an unreferred group of 6-year-olds with a history of severe nonorganic growth retardation, sampled from a 1-year birth cohort in an inner-city area of South London. Children who failed to thrive in infancy (weight below the third centile for at least 3 months) and their pairwise matched comparisons were originally studied at 15 months, and 42 cases and 42 controls (89.5% of the sample) were followed up. At 6 years, previously growth-retarded children were considerably smaller than matched comparisons, in terms of body mass index (BMI), and height and weight for age z scores. History of FTT explained substantial variance in weight and BMI at 6 years, with maternal height also contributing to variation in height for age. Child cognitive functioning at 6 years was examined using the McCarthy Scales: cases had more limited quantitative and memory skills than comparisons, but there was no intergroup variation in general cognitive performance. In contrast to analyses of physical development, failure to thrive did not account for cognitive functioning; maternal IQ was the sole significant predictor of performance on all indices of child cognitive abilities. At 15 months, earlier growth faltering was linked to limitations in mental development, but these findings were not confirmed by the follow-up data: the timing of FTT was not related to cognitive abilities at 6 years. Results correspond to past research indicating that nonorganic failure to thrive is associated with persistent limitations in physical stature. There was little evidence of cognitive disadvantage for case group children at school age, suggesting that the adverse effects of early malnutrition on cognitive functioning appear to diminish over time. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=125
in Journal of Child Psychology and Psychiatry > 41-8 (November 2000) . - p.1003-1014[article] The Developmental Sequelae of Nonorganic Failure to Thrive [Texte imprimé et/ou numérique] / Janet BODDY, Auteur ; David H. SKUSE, Auteur ; Bernice ANDREWS, Auteur . - 2000 . - p.1003-1014.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 41-8 (November 2000) . - p.1003-1014
Mots-clés : Child development failure to thrive follow-up studies growth retardation longitudinal studies school children Index. décimale : PER Périodiques Résumé : The developmental sequelae of infant failure to thrive (FTT) were examined in an unreferred group of 6-year-olds with a history of severe nonorganic growth retardation, sampled from a 1-year birth cohort in an inner-city area of South London. Children who failed to thrive in infancy (weight below the third centile for at least 3 months) and their pairwise matched comparisons were originally studied at 15 months, and 42 cases and 42 controls (89.5% of the sample) were followed up. At 6 years, previously growth-retarded children were considerably smaller than matched comparisons, in terms of body mass index (BMI), and height and weight for age z scores. History of FTT explained substantial variance in weight and BMI at 6 years, with maternal height also contributing to variation in height for age. Child cognitive functioning at 6 years was examined using the McCarthy Scales: cases had more limited quantitative and memory skills than comparisons, but there was no intergroup variation in general cognitive performance. In contrast to analyses of physical development, failure to thrive did not account for cognitive functioning; maternal IQ was the sole significant predictor of performance on all indices of child cognitive abilities. At 15 months, earlier growth faltering was linked to limitations in mental development, but these findings were not confirmed by the follow-up data: the timing of FTT was not related to cognitive abilities at 6 years. Results correspond to past research indicating that nonorganic failure to thrive is associated with persistent limitations in physical stature. There was little evidence of cognitive disadvantage for case group children at school age, suggesting that the adverse effects of early malnutrition on cognitive functioning appear to diminish over time. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=125 Toward specifying pervasive developmental disorder—not otherwise specified / William P.L. MANDY in Autism Research, 4-2 (April 2011)
[article]
Titre : Toward specifying pervasive developmental disorder—not otherwise specified Type de document : Texte imprimé et/ou numérique Auteurs : William P.L. MANDY, Auteur ; Tony CHARMAN, Auteur ; Jane GILMOUR, Auteur ; David H. SKUSE, Auteur Année de publication : 2011 Article en page(s) : p.121-131 Langues : Anglais (eng) Mots-clés : pervasive developmental disorder—not otherwise specified (PDD-NOS) Autistic disorder Asperger's disorder autism spectrum disorder diagnostic and statistical manual (DSM) Index. décimale : PER Périodiques Résumé : Pervasive developmental disorder—not otherwise specified (PDD-NOS) is the most common and least satisfactory of the PDD diagnoses. It is not formally operationalized, which limits its reliability and has hampered attempts to assess its validity. We aimed, first, to improve the reliability and replicability of PDD-NOS by operationalizing its DSM-IV-TR description and, second, to test its validity through comparison with autistic disorder (AD) and Asperger's disorder (AsD). In a sample of 256 young people (mean age = 9.1 years) we used Developmental, Diagnostic and Dimensional (3Di) algorithmic analysis to classify DSM-IV-TR AD (n = 97), AsD (n = 93) and PDD-NOS (n = 66). Groups were compared on independent measures of core PDD symptomatology, associated autistic features, and intelligence. Contrary to the assumption that PDD-NOS is heterogeneous, almost all (97%) of those with PDD-NOS had one distinct symptom pattern, namely impairments in social reciprocity and communication, without significant repetitive and stereotyped behaviors (RSB). Compared to AD and AsD, they had comparably severe but more circumscribed social communication difficulties, with fewer non-social features of autism, such as sensory, feeding and visuo-spatial problems. These individuals appear to have a distinct variant of autism that does not merely sit at the less severe end of the same continuum of symptoms. The current draft guidelines for DSM-V, which mandate the presence of RSBs for any PDD diagnosis, would exclude such people from the autistic spectrum. En ligne : http://dx.doi.org/10.1002/aur.178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121
in Autism Research > 4-2 (April 2011) . - p.121-131[article] Toward specifying pervasive developmental disorder—not otherwise specified [Texte imprimé et/ou numérique] / William P.L. MANDY, Auteur ; Tony CHARMAN, Auteur ; Jane GILMOUR, Auteur ; David H. SKUSE, Auteur . - 2011 . - p.121-131.
Langues : Anglais (eng)
in Autism Research > 4-2 (April 2011) . - p.121-131
Mots-clés : pervasive developmental disorder—not otherwise specified (PDD-NOS) Autistic disorder Asperger's disorder autism spectrum disorder diagnostic and statistical manual (DSM) Index. décimale : PER Périodiques Résumé : Pervasive developmental disorder—not otherwise specified (PDD-NOS) is the most common and least satisfactory of the PDD diagnoses. It is not formally operationalized, which limits its reliability and has hampered attempts to assess its validity. We aimed, first, to improve the reliability and replicability of PDD-NOS by operationalizing its DSM-IV-TR description and, second, to test its validity through comparison with autistic disorder (AD) and Asperger's disorder (AsD). In a sample of 256 young people (mean age = 9.1 years) we used Developmental, Diagnostic and Dimensional (3Di) algorithmic analysis to classify DSM-IV-TR AD (n = 97), AsD (n = 93) and PDD-NOS (n = 66). Groups were compared on independent measures of core PDD symptomatology, associated autistic features, and intelligence. Contrary to the assumption that PDD-NOS is heterogeneous, almost all (97%) of those with PDD-NOS had one distinct symptom pattern, namely impairments in social reciprocity and communication, without significant repetitive and stereotyped behaviors (RSB). Compared to AD and AsD, they had comparably severe but more circumscribed social communication difficulties, with fewer non-social features of autism, such as sensory, feeding and visuo-spatial problems. These individuals appear to have a distinct variant of autism that does not merely sit at the less severe end of the same continuum of symptoms. The current draft guidelines for DSM-V, which mandate the presence of RSBs for any PDD diagnosis, would exclude such people from the autistic spectrum. En ligne : http://dx.doi.org/10.1002/aur.178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 Translation and validation of the developmental, dimensional and diagnostic interview (3Di) for diagnosis of autism spectrum disorder in Thai children / Jariya CHUTHAPISITH in Autism, 16-4 (July 2012)
[article]
Titre : Translation and validation of the developmental, dimensional and diagnostic interview (3Di) for diagnosis of autism spectrum disorder in Thai children Type de document : Texte imprimé et/ou numérique Auteurs : Jariya CHUTHAPISITH, Auteur ; Pasinee TAYCHARPIPRANAI, Auteur ; Nichara RUANGDARAGANON, Auteur ; Richard WARRINGTON, Auteur ; David H. SKUSE, Auteur Année de publication : 2012 Article en page(s) : p.350-356 Langues : Anglais (eng) Mots-clés : 3Di autism spectrum disorders ASDs autism diagnosis Index. décimale : PER Périodiques Résumé : This study aimed to examine the effectiveness of a translated version of the short version of the Developmental, Dimensional and Diagnostic Interview (3Di) in discriminating children with autism spectrum disorders (ASDs) from typically developing children. Two groups, comprising 63 children with clinically ascertained ASDs and 67 typically developing children, were interviewed with the short 3Di translated version. Mean 3Di scale scores in each domain of autistic symptoms (social reciprocity, communication, and repetitive/stereotyped behaviors) were significantly higher in the ASD group than in the typically developing group. The optimal receiver operating characteristics curve cut-off scores were found to be 10, 8, and 3 for social reciprocity domain, communication domain, and repetitive/stereotyped behaviors domain, respectively, which are identical to the original English standardization. Corresponding sensitivities and specificities were 76.2% and 80.9% for the social reciprocity domain; 85.7% and 73.5% for the communication domain; and 66.7% and 80.9% for the repetitive behaviors domain. The areas under the curve were 0.89 (95% CI = 0.84–0.94), 0.88 (95% CI = 0.82–0.94), and 0.79 (95% CI = 0.71–0.87), respectively. The short 3Di-Thai version is found to be a useful diagnostic instrument for differentiating between clinically diagnosed children with ASDs and typically developing children, although further replication is needed. En ligne : http://dx.doi.org/10.1177/1362361311433770 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178
in Autism > 16-4 (July 2012) . - p.350-356[article] Translation and validation of the developmental, dimensional and diagnostic interview (3Di) for diagnosis of autism spectrum disorder in Thai children [Texte imprimé et/ou numérique] / Jariya CHUTHAPISITH, Auteur ; Pasinee TAYCHARPIPRANAI, Auteur ; Nichara RUANGDARAGANON, Auteur ; Richard WARRINGTON, Auteur ; David H. SKUSE, Auteur . - 2012 . - p.350-356.
Langues : Anglais (eng)
in Autism > 16-4 (July 2012) . - p.350-356
Mots-clés : 3Di autism spectrum disorders ASDs autism diagnosis Index. décimale : PER Périodiques Résumé : This study aimed to examine the effectiveness of a translated version of the short version of the Developmental, Dimensional and Diagnostic Interview (3Di) in discriminating children with autism spectrum disorders (ASDs) from typically developing children. Two groups, comprising 63 children with clinically ascertained ASDs and 67 typically developing children, were interviewed with the short 3Di translated version. Mean 3Di scale scores in each domain of autistic symptoms (social reciprocity, communication, and repetitive/stereotyped behaviors) were significantly higher in the ASD group than in the typically developing group. The optimal receiver operating characteristics curve cut-off scores were found to be 10, 8, and 3 for social reciprocity domain, communication domain, and repetitive/stereotyped behaviors domain, respectively, which are identical to the original English standardization. Corresponding sensitivities and specificities were 76.2% and 80.9% for the social reciprocity domain; 85.7% and 73.5% for the communication domain; and 66.7% and 80.9% for the repetitive behaviors domain. The areas under the curve were 0.89 (95% CI = 0.84–0.94), 0.88 (95% CI = 0.82–0.94), and 0.79 (95% CI = 0.71–0.87), respectively. The short 3Di-Thai version is found to be a useful diagnostic instrument for differentiating between clinically diagnosed children with ASDs and typically developing children, although further replication is needed. En ligne : http://dx.doi.org/10.1177/1362361311433770 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178