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Détail de l'auteur
Auteur Diane L. WILLIAMS |
Documents disponibles écrits par cet auteur (15)



Aberrant functioning of the theory-of-mind network in children and adolescents with autism / Rajesh K. KANA in Molecular Autism, (October 2015)
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Titre : Aberrant functioning of the theory-of-mind network in children and adolescents with autism Type de document : Texte imprimé et/ou numérique Auteurs : Rajesh K. KANA, Auteur ; Jose O. MAXIMO, Auteur ; Diane L. WILLIAMS, Auteur ; Timothy A. KELLER, Auteur ; Sarah E. SCHIPUL, Auteur ; Vladimir L. CHERKASSKY, Auteur ; Nancy J. MINSHEW, Auteur ; Marcel Adam JUST, Auteur Article en page(s) : p.1-12 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Theory-of-mind (ToM), the ability to infer people’s thoughts and feelings, is a pivotal skill in effective social interactions. Individuals with autism spectrum disorders (ASD) have been found to have altered ToM skills, which significantly impacts the quality of their social interactions. Neuroimaging studies have reported altered activation of the ToM cortical network, especially in adults with autism, yet little is known about the brain responses underlying ToM in younger individuals with ASD. This functional magnetic resonance imaging (fMRI) study investigated the neural mechanisms underlying ToM in high-functioning children and adolescents with ASD and matched typically developing (TD) peers. En ligne : http://dx.doi.org/10.1186/s13229-015-0052-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277
in Molecular Autism > (October 2015) . - p.1-12[article] Aberrant functioning of the theory-of-mind network in children and adolescents with autism [Texte imprimé et/ou numérique] / Rajesh K. KANA, Auteur ; Jose O. MAXIMO, Auteur ; Diane L. WILLIAMS, Auteur ; Timothy A. KELLER, Auteur ; Sarah E. SCHIPUL, Auteur ; Vladimir L. CHERKASSKY, Auteur ; Nancy J. MINSHEW, Auteur ; Marcel Adam JUST, Auteur . - p.1-12.
Langues : Anglais (eng)
in Molecular Autism > (October 2015) . - p.1-12
Index. décimale : PER Périodiques Résumé : Theory-of-mind (ToM), the ability to infer people’s thoughts and feelings, is a pivotal skill in effective social interactions. Individuals with autism spectrum disorders (ASD) have been found to have altered ToM skills, which significantly impacts the quality of their social interactions. Neuroimaging studies have reported altered activation of the ToM cortical network, especially in adults with autism, yet little is known about the brain responses underlying ToM in younger individuals with ASD. This functional magnetic resonance imaging (fMRI) study investigated the neural mechanisms underlying ToM in high-functioning children and adolescents with ASD and matched typically developing (TD) peers. En ligne : http://dx.doi.org/10.1186/s13229-015-0052-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 Are Children with Autism More Responsive to Animated Characters? A Study of Interactions with Humans and Human-Controlled Avatars / Elizabeth J. CARTER in Journal of Autism and Developmental Disorders, 44-10 (October 2014)
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Titre : Are Children with Autism More Responsive to Animated Characters? A Study of Interactions with Humans and Human-Controlled Avatars Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth J. CARTER, Auteur ; Diane L. WILLIAMS, Auteur ; Jessica K. HODGINS, Auteur ; Jill F. LEHMAN, Auteur Article en page(s) : p.2475-2485 Langues : Anglais (eng) Mots-clés : Autism Animated characters Computer-assisted technology Computer-based interactions Communication Avatars Index. décimale : PER Périodiques Résumé : Few direct comparisons have been made between the responsiveness of children with autism to computer-generated or animated characters and their responsiveness to humans. Twelve 4- to 8-year-old children with autism interacted with a human therapist; a human-controlled, interactive avatar in a theme park; a human actor speaking like the avatar; and cartoon characters who sought social responses. We found superior gestural and verbal responses to the therapist; intermediate response levels to the avatar and the actor; and poorest responses to the cartoon characters, although attention was equivalent across conditions. These results suggest that even avatars that provide live, responsive interactions are not superior to human therapists in eliciting verbal and non-verbal communication from children with autism in this age range. En ligne : http://dx.doi.org/10.1007/s10803-014-2116-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2475-2485[article] Are Children with Autism More Responsive to Animated Characters? A Study of Interactions with Humans and Human-Controlled Avatars [Texte imprimé et/ou numérique] / Elizabeth J. CARTER, Auteur ; Diane L. WILLIAMS, Auteur ; Jessica K. HODGINS, Auteur ; Jill F. LEHMAN, Auteur . - p.2475-2485.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2475-2485
Mots-clés : Autism Animated characters Computer-assisted technology Computer-based interactions Communication Avatars Index. décimale : PER Périodiques Résumé : Few direct comparisons have been made between the responsiveness of children with autism to computer-generated or animated characters and their responsiveness to humans. Twelve 4- to 8-year-old children with autism interacted with a human therapist; a human-controlled, interactive avatar in a theme park; a human actor speaking like the avatar; and cartoon characters who sought social responses. We found superior gestural and verbal responses to the therapist; intermediate response levels to the avatar and the actor; and poorest responses to the cartoon characters, although attention was equivalent across conditions. These results suggest that even avatars that provide live, responsive interactions are not superior to human therapists in eliciting verbal and non-verbal communication from children with autism in this age range. En ligne : http://dx.doi.org/10.1007/s10803-014-2116-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240 Associations Between Conceptual Reasoning, Problem Solving, and Adaptive Ability in High-functioning Autism / Diane L. WILLIAMS in Journal of Autism and Developmental Disorders, 44-11 (November 2014)
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Titre : Associations Between Conceptual Reasoning, Problem Solving, and Adaptive Ability in High-functioning Autism Type de document : Texte imprimé et/ou numérique Auteurs : Diane L. WILLIAMS, Auteur ; Carla A. MAZEFSKY, Auteur ; Jon D. WALKER, Auteur ; Nancy J. MINSHEW, Auteur ; Gerald GOLDSTEIN, Auteur Article en page(s) : p.2908-2920 Langues : Anglais (eng) Mots-clés : Autism Conceptual reasoning Problem solving Adaptive behavior Cognitive Index. décimale : PER Périodiques Résumé : Abstract thinking is generally highly correlated with problem-solving ability which is predictive of better adaptive functioning. Measures of conceptual reasoning, an ecologically-valid laboratory measure of problem-solving, and a report measure of adaptive functioning in the natural environment, were administered to children and adults with and without autism. The individuals with autism had weaker conceptual reasoning ability than individuals with typical development of similar age and cognitive ability. For the autism group, their flexible thinking scores were significantly correlated with laboratory measures of strategy formation and rule shifting and with reported overall adaptive behavior but not socialization scores. Therefore, in autism, flexibility of thought is potentially more important for adaptive functioning in the natural environment than conceptual reasoning or problem-solving. En ligne : http://dx.doi.org/10.1007/s10803-014-2190-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241
in Journal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2908-2920[article] Associations Between Conceptual Reasoning, Problem Solving, and Adaptive Ability in High-functioning Autism [Texte imprimé et/ou numérique] / Diane L. WILLIAMS, Auteur ; Carla A. MAZEFSKY, Auteur ; Jon D. WALKER, Auteur ; Nancy J. MINSHEW, Auteur ; Gerald GOLDSTEIN, Auteur . - p.2908-2920.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2908-2920
Mots-clés : Autism Conceptual reasoning Problem solving Adaptive behavior Cognitive Index. décimale : PER Périodiques Résumé : Abstract thinking is generally highly correlated with problem-solving ability which is predictive of better adaptive functioning. Measures of conceptual reasoning, an ecologically-valid laboratory measure of problem-solving, and a report measure of adaptive functioning in the natural environment, were administered to children and adults with and without autism. The individuals with autism had weaker conceptual reasoning ability than individuals with typical development of similar age and cognitive ability. For the autism group, their flexible thinking scores were significantly correlated with laboratory measures of strategy formation and rule shifting and with reported overall adaptive behavior but not socialization scores. Therefore, in autism, flexibility of thought is potentially more important for adaptive functioning in the natural environment than conceptual reasoning or problem-solving. En ligne : http://dx.doi.org/10.1007/s10803-014-2190-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 Brain Function Differences in Language Processing in Children and Adults with Autism / Diane L. WILLIAMS in Autism Research, 6-4 (August 2013)
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Titre : Brain Function Differences in Language Processing in Children and Adults with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Diane L. WILLIAMS, Auteur ; Vladimir L. CHERKASSKY, Auteur ; Robert A. MASON, Auteur ; Timothy A. KELLER, Auteur ; Nancy J. MINSHEW, Auteur ; Marcel Adam JUST, Auteur Article en page(s) : p.288-302 Langues : Anglais (eng) Mots-clés : FMRI language processing development functional connectivity Index. décimale : PER Périodiques Résumé : Comparison of brain function between children and adults with autism provides an understanding of the effects of the disorder and associated maturational differences on language processing. Functional imaging (functional magnetic resonance imaging) was used to examine brain activation and cortical synchronization during the processing of literal and ironic texts in 15 children with autism, 14 children with typical development, 13 adults with autism, and 12 adult controls. Both the children and adults with autism had lower functional connectivity (synchronization of brain activity among activated areas) than their age and ability comparison group in the left hemisphere language network during irony processing, and neither autism group had an increase in functional connectivity in response to increased task demands. Activation differences for the literal and irony conditions occurred in key language-processing regions (left middle temporal, left pars triangularis, left pars opercularis, left medial frontal, and right middle temporal). The children and adults with autism differed from each other in the use of some brain regions during the irony task, with the adults with autism having activation levels similar to those of the control groups. Overall, the children and adults with autism differed from the adult and child controls in (a) the degree of network coordination, (b) the distribution of the workload among member nodes, and (3) the dynamic recruitment of regions in response to text content. Moreover, the differences between the two autism age groups may be indicative of positive changes in the neural function related to language processing associated with maturation and/or educational experience. En ligne : http://dx.doi.org/10.1002/aur.1291 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212
in Autism Research > 6-4 (August 2013) . - p.288-302[article] Brain Function Differences in Language Processing in Children and Adults with Autism [Texte imprimé et/ou numérique] / Diane L. WILLIAMS, Auteur ; Vladimir L. CHERKASSKY, Auteur ; Robert A. MASON, Auteur ; Timothy A. KELLER, Auteur ; Nancy J. MINSHEW, Auteur ; Marcel Adam JUST, Auteur . - p.288-302.
Langues : Anglais (eng)
in Autism Research > 6-4 (August 2013) . - p.288-302
Mots-clés : FMRI language processing development functional connectivity Index. décimale : PER Périodiques Résumé : Comparison of brain function between children and adults with autism provides an understanding of the effects of the disorder and associated maturational differences on language processing. Functional imaging (functional magnetic resonance imaging) was used to examine brain activation and cortical synchronization during the processing of literal and ironic texts in 15 children with autism, 14 children with typical development, 13 adults with autism, and 12 adult controls. Both the children and adults with autism had lower functional connectivity (synchronization of brain activity among activated areas) than their age and ability comparison group in the left hemisphere language network during irony processing, and neither autism group had an increase in functional connectivity in response to increased task demands. Activation differences for the literal and irony conditions occurred in key language-processing regions (left middle temporal, left pars triangularis, left pars opercularis, left medial frontal, and right middle temporal). The children and adults with autism differed from each other in the use of some brain regions during the irony task, with the adults with autism having activation levels similar to those of the control groups. Overall, the children and adults with autism differed from the adult and child controls in (a) the degree of network coordination, (b) the distribution of the workload among member nodes, and (3) the dynamic recruitment of regions in response to text content. Moreover, the differences between the two autism age groups may be indicative of positive changes in the neural function related to language processing associated with maturation and/or educational experience. En ligne : http://dx.doi.org/10.1002/aur.1291 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 Brief Report: Visuospatial and Spoken Language Recall in Autism: Preliminary Findings / Kelly L. COBURN in Journal of Autism and Developmental Disorders, 52-6 (June 2022)
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Titre : Brief Report: Visuospatial and Spoken Language Recall in Autism: Preliminary Findings Type de document : Texte imprimé et/ou numérique Auteurs : Kelly L. COBURN, Auteur ; Diane L. WILLIAMS, Auteur Article en page(s) : p.2831-2837 Langues : Anglais (eng) Mots-clés : Autism Communication Multimodal Recall Spoken language Visuospatial Index. décimale : PER Périodiques Résumé : Challenges to verbal encoding may affect the ability of autistic individuals to express their ideas. Therefore, visuospatial expression may represent a person's knowledge and skills more accurately than spoken language. To test this hypothesis, we asked seven autistic adults to linguistically retell and visuospatially reenact several animated clips. On average, visuospatial responses contained more correct elements than spoken responses. The level of intention of the three stimulus categories did not systematically affect response accuracy. Participants who produced visuospatial responses before spoken responses and those who had watched a greater number of stimuli assigned higher intentionality to shapes in the animations that were designed to elicit mentalizing. The modality used for expression may affect accuracy of responses by autistic individuals. En ligne : http://dx.doi.org/10.1007/s10803-021-05143-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474
in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2831-2837[article] Brief Report: Visuospatial and Spoken Language Recall in Autism: Preliminary Findings [Texte imprimé et/ou numérique] / Kelly L. COBURN, Auteur ; Diane L. WILLIAMS, Auteur . - p.2831-2837.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2831-2837
Mots-clés : Autism Communication Multimodal Recall Spoken language Visuospatial Index. décimale : PER Périodiques Résumé : Challenges to verbal encoding may affect the ability of autistic individuals to express their ideas. Therefore, visuospatial expression may represent a person's knowledge and skills more accurately than spoken language. To test this hypothesis, we asked seven autistic adults to linguistically retell and visuospatially reenact several animated clips. On average, visuospatial responses contained more correct elements than spoken responses. The level of intention of the three stimulus categories did not systematically affect response accuracy. Participants who produced visuospatial responses before spoken responses and those who had watched a greater number of stimuli assigned higher intentionality to shapes in the animations that were designed to elicit mentalizing. The modality used for expression may affect accuracy of responses by autistic individuals. En ligne : http://dx.doi.org/10.1007/s10803-021-05143-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 A comparison of measures for assessing the level and nature of intelligence in verbal children and adults with autism spectrum disorder / Kimberly E. BODNER in Research in Autism Spectrum Disorders, 8-11 (November 2014)
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PermalinkCortical underconnectivity coupled with preserved visuospatial cognition in autism: Evidence from an fMRI study of an embedded figures task / Saudamini Roy DAMARLA in Autism Research, 3-5 (October 2010)
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PermalinkDo individuals with high functioning autism have the IQ profile associated with nonverbal learning disability? / Diane L. WILLIAMS in Research in Autism Spectrum Disorders, 2-2 (April-June 2008)
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PermalinkFurther understanding of complex information processing in verbal adolescents and adults with autism spectrum disorders / Diane L. WILLIAMS in Autism, 19-7 (October 2015)
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PermalinkPermalinkMaking Inferences: Comprehension of Physical Causality, Intentionality, and Emotions in Discourse by High-Functioning Older Children, Adolescents, and Adults with Autism / Kimberly E. BODNER in Journal of Autism and Developmental Disorders, 45-9 (September 2015)
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PermalinkPermalinkQuantitative analysis of the shape of the corpus callosum in patients with autism and comparison individuals / Manuel F. CASANOVA in Autism, 15-2 (March 2011)
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PermalinkPermalinkThe Modality Shift Experiment in Adults and Children with High Functioning Autism / Diane L. WILLIAMS in Journal of Autism and Developmental Disorders, 43-4 (April 2013)
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