Autism spectrum disorder/Takiw?tanga: An Integrated Data Infrastructure-based approach to autism spectrum disorder research in New Zealand / Nicholas J. BOWDEN in Autism, 24-8 (November 2020)  

Public ISBD [article]  inAutism > 24-8 (November 2020) . - p.2213-2227 Titre : Autism spectrum disorder/Takiw?tanga: An Integrated Data Infrastructure-based approach to autism spectrum disorder research in New Zealand Type de document : Texte imprimé et/ou numérique Auteurs : Nicholas J. BOWDEN, Auteur ; Hiran THABREW, Auteur ; Jesse KOKAUA, Auteur ; Richard AUDAS, Auteur ; Barry MILNE, Auteur ; Kirsten SMILER, Auteur ; Hilary STACE, Auteur ; Barry TAYLOR, Auteur ; Sheree GIBB, Auteur Article en page(s) : p.2213-2227 Langues : Anglais (eng) Mots-clés : *Integrated Data Infrastructure  *autism spectrum disorder  *big data  *case identification  *mental health Index. décimale : PER Périodiques Résumé : New Zealand has few estimates of the prevalence autism spectrum disorder and no national registry or data set to identify and track cases. This hinders the ability to make informed, evidence-based decisions relating to autism spectrum disorder. In this study, we utilised linked health and non-health data to develop a method for identifying cases of autism spectrum disorder among children and young people in New Zealand. In addition, we examined rates of co-occurring mental health, neurodevelopmental and related conditions among this cohort and compared these to the general population. The method identified almost 10,000 children and young people with autism spectrum disorder in New Zealand. Co-occurring mental health or related problems were found in over 68% of this group (nearly seven times higher than the general population), and around half were identified with multiple co-occurring conditions. The most frequently identified conditions were intellectual disability, disruptive behaviours and emotional problems. We have developed a useful method for monitoring service and treatment-related trends, number and types of co-occurring conditions and examining social outcomes among individuals with autism spectrum disorder. While the method may underestimate the prevalence of autism spectrum disorder in New Zealand, it provides a significant step towards establishing a more comprehensive evidence base to inform autism spectrum disorder-related policy. En ligne : http://dx.doi.org/10.1177/1362361320939329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=431 [article] Autism spectrum disorder/Takiw?tanga: An Integrated Data Infrastructure-based approach to autism spectrum disorder research in New Zealand [Texte imprimé et/ou numérique] / Nicholas J. BOWDEN, Auteur ; Hiran THABREW, Auteur ; Jesse KOKAUA, Auteur ; Richard AUDAS, Auteur ; Barry MILNE, Auteur ; Kirsten SMILER, Auteur ; Hilary STACE, Auteur ; Barry TAYLOR, Auteur ; Sheree GIBB, Auteur . - p.2213-2227. Langues : Anglais (eng) in Autism > 24-8 (November 2020) . - p.2213-2227 Mots-clés : *Integrated Data Infrastructure  *autism spectrum disorder  *big data  *case identification  *mental health Index. décimale : PER Périodiques Résumé : New Zealand has few estimates of the prevalence autism spectrum disorder and no national registry or data set to identify and track cases. This hinders the ability to make informed, evidence-based decisions relating to autism spectrum disorder. In this study, we utilised linked health and non-health data to develop a method for identifying cases of autism spectrum disorder among children and young people in New Zealand. In addition, we examined rates of co-occurring mental health, neurodevelopmental and related conditions among this cohort and compared these to the general population. The method identified almost 10,000 children and young people with autism spectrum disorder in New Zealand. Co-occurring mental health or related problems were found in over 68% of this group (nearly seven times higher than the general population), and around half were identified with multiple co-occurring conditions. The most frequently identified conditions were intellectual disability, disruptive behaviours and emotional problems. We have developed a useful method for monitoring service and treatment-related trends, number and types of co-occurring conditions and examining social outcomes among individuals with autism spectrum disorder. While the method may underestimate the prevalence of autism spectrum disorder in New Zealand, it provides a significant step towards establishing a more comprehensive evidence base to inform autism spectrum disorder-related policy. En ligne : http://dx.doi.org/10.1177/1362361320939329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=431

Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study / Hayley GUINEY in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.219-235 Titre : Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study Type de document : Texte imprimé et/ou numérique Auteurs : Hayley GUINEY, Auteur ; Avshalom CASPI, Auteur ; Antony AMBLER, Auteur ; Jay BELSKY, Auteur ; Jesse KOKAUA, Auteur ; Jonathan BROADBENT, Auteur ; Kirsten CHEYNE, Auteur ; Nigel DICKSON, Auteur ; Robert J. HANCOX, Auteur ; Honalee HARRINGTON, Auteur ; Sean HOGAN, Auteur ; Sandhya RAMRAKHA, Auteur ; Antoinette RIGHARTS, Auteur ; W. Murray THOMSON, Auteur ; Terrie E. MOFFITT, Auteur ; Richie POULTON, Auteur Article en page(s) : p.219-235 Langues : Anglais (eng) Mots-clés : child sexual abuseconsequences  long-term outcomes  longitudinal  multi-morbidity Index. décimale : PER Périodiques Résumé : The aim of this study was to use longitudinal population-based data to examine the associations between childhood sexual abuse (CSA) and risk for adverse outcomes in multiple life domains across adulthood. In 937 individuals followed from birth to age 45y, we assessed associations between CSA (retrospectively reported at age 26y) and the experience of 22 adverse outcomes in seven domains (physical, mental, sexual, interpersonal, economic, antisocial, multi-domain) from young adulthood to midlife (26 to 45y). Analyses controlled for sex, socioeconomic status, prospectively reported child harm and household dysfunction adverse childhood experiences, and adult sexual assault, and considered different definitions of CSA. After adjusting for confounders, CSA survivors were more likely than their peers to experience internalizing, externalizing, and thought disorders, suicide attempts, health risk behaviors, systemic inflammation, poor oral health, sexually transmitted diseases, high-conflict relationships, benefit use, financial difficulties, antisocial behavior, and cumulative problems across multiple domains in adulthood. In sum, CSA was associated with multiple persistent problems across adulthood, even after adjusting for confounding life stressors, and the risk for particular problems incremented with CSA severity. The higher risk for most specific problems was small to moderate, but the cumulative long-term effects across multiple domains reflect considerable individual and societal burden. En ligne : https://dx.doi.org/10.1017/S0954579422001146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study [Texte imprimé et/ou numérique] / Hayley GUINEY, Auteur ; Avshalom CASPI, Auteur ; Antony AMBLER, Auteur ; Jay BELSKY, Auteur ; Jesse KOKAUA, Auteur ; Jonathan BROADBENT, Auteur ; Kirsten CHEYNE, Auteur ; Nigel DICKSON, Auteur ; Robert J. HANCOX, Auteur ; Honalee HARRINGTON, Auteur ; Sean HOGAN, Auteur ; Sandhya RAMRAKHA, Auteur ; Antoinette RIGHARTS, Auteur ; W. Murray THOMSON, Auteur ; Terrie E. MOFFITT, Auteur ; Richie POULTON, Auteur . - p.219-235. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.219-235 Mots-clés : child sexual abuseconsequences  long-term outcomes  longitudinal  multi-morbidity Index. décimale : PER Périodiques Résumé : The aim of this study was to use longitudinal population-based data to examine the associations between childhood sexual abuse (CSA) and risk for adverse outcomes in multiple life domains across adulthood. In 937 individuals followed from birth to age 45y, we assessed associations between CSA (retrospectively reported at age 26y) and the experience of 22 adverse outcomes in seven domains (physical, mental, sexual, interpersonal, economic, antisocial, multi-domain) from young adulthood to midlife (26 to 45y). Analyses controlled for sex, socioeconomic status, prospectively reported child harm and household dysfunction adverse childhood experiences, and adult sexual assault, and considered different definitions of CSA. After adjusting for confounders, CSA survivors were more likely than their peers to experience internalizing, externalizing, and thought disorders, suicide attempts, health risk behaviors, systemic inflammation, poor oral health, sexually transmitted diseases, high-conflict relationships, benefit use, financial difficulties, antisocial behavior, and cumulative problems across multiple domains in adulthood. In sum, CSA was associated with multiple persistent problems across adulthood, even after adjusting for confounding life stressors, and the risk for particular problems incremented with CSA severity. The higher risk for most specific problems was small to moderate, but the cumulative long-term effects across multiple domains reflect considerable individual and societal burden. En ligne : https://dx.doi.org/10.1017/S0954579422001146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

National prescribing rates and polypharmacy for children and young people in New Zealand with and without autism spectrum disorder / Nicholas J. BOWDEN in Research in Autism Spectrum Disorders, 78 (October 2020)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 78 (October 2020) . - 101642 Titre : National prescribing rates and polypharmacy for children and young people in New Zealand with and without autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Nicholas J. BOWDEN, Auteur ; Hiran THABREW, Auteur ; Jesse KOKAUA, Auteur ; Rhiannon BRAUND, Auteur Article en page(s) : 101642 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Children  Adolescents  Pharmacotherapy  Integrated Data Infrastructure  Polypharmacy Index. décimale : PER Périodiques Résumé : Background International data and guidance on prescribing for children and young people with autism spectrum disorder (ASD) are limited. National administrative datasets such as the New Zealand Integrated Data Infrastructure (IDI) may offer a cost-effective and sustainable way to monitor prescribing trends in the context of clinical and systemic change. Method Medication dispensing for New Zealand children and young people with ASD was explored using the IDI. Psychotropic and non-psychotropic medication dispensing rates, and rates of polypharmacy within a one-year period were examined. Comparisons of medication use were made to children and young people with another neurodevelopmental condition, attention deficit hyperactivity disorder (ADHD), and the general population. Results The vast majority (83 %) of children and young people with ASD were prescribed medication within a one-year period and they received a mean of four unique medications. High dispensing of antihistamine, asthma, gastrointestinal, and psychotropic medications was observed. Just over half (57 %) of those with ASD experienced polypharmacy of three or more medications, and 11 % of 10 or more. Medication dispensing rates were significantly higher among the ASD group compared to those with ADHD and the general population. Polypharmacy rates were higher among both the ASD and ADHD group compared to the general population. Conclusions It is clear that New Zealand children and young people with ASD experience a significant and disproportionate medication burden. Although further investigation is needed to fully understand underlying reasons and clinical implications, the IDI appears to be a valuable means of monitoring prescribing trends over time. En ligne : https://doi.org/10.1016/j.rasd.2020.101642 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] National prescribing rates and polypharmacy for children and young people in New Zealand with and without autism spectrum disorder [Texte imprimé et/ou numérique] / Nicholas J. BOWDEN, Auteur ; Hiran THABREW, Auteur ; Jesse KOKAUA, Auteur ; Rhiannon BRAUND, Auteur . - 101642. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 78 (October 2020) . - 101642 Mots-clés : Autism spectrum disorder  Children  Adolescents  Pharmacotherapy  Integrated Data Infrastructure  Polypharmacy Index. décimale : PER Périodiques Résumé : Background International data and guidance on prescribing for children and young people with autism spectrum disorder (ASD) are limited. National administrative datasets such as the New Zealand Integrated Data Infrastructure (IDI) may offer a cost-effective and sustainable way to monitor prescribing trends in the context of clinical and systemic change. Method Medication dispensing for New Zealand children and young people with ASD was explored using the IDI. Psychotropic and non-psychotropic medication dispensing rates, and rates of polypharmacy within a one-year period were examined. Comparisons of medication use were made to children and young people with another neurodevelopmental condition, attention deficit hyperactivity disorder (ADHD), and the general population. Results The vast majority (83 %) of children and young people with ASD were prescribed medication within a one-year period and they received a mean of four unique medications. High dispensing of antihistamine, asthma, gastrointestinal, and psychotropic medications was observed. Just over half (57 %) of those with ASD experienced polypharmacy of three or more medications, and 11 % of 10 or more. Medication dispensing rates were significantly higher among the ASD group compared to those with ADHD and the general population. Polypharmacy rates were higher among both the ASD and ADHD group compared to the general population. Conclusions It is clear that New Zealand children and young people with ASD experience a significant and disproportionate medication burden. Although further investigation is needed to fully understand underlying reasons and clinical implications, the IDI appears to be a valuable means of monitoring prescribing trends over time. En ligne : https://doi.org/10.1016/j.rasd.2020.101642 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

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