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Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners / R. STURNER in Molecular Autism, 13 (2022)
[article]
Titre : Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners Type de document : Texte imprimé et/ou numérique Auteurs : R. STURNER, Auteur ; B. HOWARD, Auteur ; P. BERGMANN, Auteur ; S. ATTAR, Auteur ; L. STEWART-ARTZ, Auteur ; K. BET, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur Article en page(s) : 2p. Langues : Anglais (eng) Mots-clés : Autism screening Developmental screening M-chat Q-CHAT Primary Care and its for-profit subsidiary, CHADIS, Inc. CHADIS, the web-tool used in the study was developed by Dr. Sturner and his spouse, Dr. Howard. Dr. Sturner is Director of the Center and Dr. Howard is President of CHADIS, Inc. Both are members of the Board of Directors of Center and are paid employees or consultants to both entities. The other authors have indicated they have no financial relationships relevant to this article to disclose. Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism screening is recommended at 18- and 24-month pediatric well visits. The Modified Checklist for Autism in Toddlers-Revised (M-CHAT-R) authors recommend a follow-up interview (M-CHAT-R/F) when positive. M-CHAT-R/F may be less accurate for 18-month-olds than 24-month-olds and accuracy for identification prior to two years is not known in samples that include children screening negative. Since autism symptoms may emerge gradually, ordinally scoring items based on the full range of response options, such as in the 10-item version of the Quantitative Checklist for Autism in Toddlers (Q-CHAT-10), might better capture autism signs than the dichotomous (i.e., yes/no) items in M-CHAT-R or the pass/fail scoring of Q-CHAT-10 items. The aims of this study were to determine and compare the accuracy of the M-CHAT-R/F and the Q-CHAT-10 and to describe the accuracy of the ordinally scored Q-CHAT-10 (Q-CHAT-10-O) for predicting autism in a sample of children who were screened at 18 months. METHODS: This is a community pediatrics validation study with screen positive (n?=?167) and age- and practice-matched screen negative children (n?=?241) recruited for diagnostic evaluations completed prior to 2 years old. Clinical diagnosis of autism was based on results of in-person diagnostic autism evaluations by research reliable testers blind to screening results and using the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) Toddler Module and Mullen Scales of Early Learning (MSEL) per standard guidelines. RESULTS: While the M-CHAT-R/F had higher specificity and PPV compared to M-CHAT-R, Q-CHAT-10-O showed higher sensitivity than M-CHAT-R/F and Q-CHAT-10. LIMITATIONS: Many parents declined participation and the sample is over-represented by higher educated parents. Results cannot be extended to older ages. CONCLUSIONS: Limitations of the currently recommended two-stage M-CHAT-R/F at the 18-month visit include low sensitivity with minimal balancing benefit of improved PPV from the follow-up interview. Ordinal, rather than dichotomous, scoring of autism screening items appears to be beneficial at this age. The Q-CHAT-10-O with ordinal scoring shows advantages to M-CHAT-R/F with half the number of items, no requirement for a follow-up interview, and improved sensitivity. Yet, Q-CHAT-10-O sensitivity is less than M-CHAT-R (without follow-up) and specificity is less than the two-stage procedure. Such limitations are consistent with recognition that screening needs to recur beyond this age. En ligne : http://dx.doi.org/10.1186/s13229-021-00480-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459
in Molecular Autism > 13 (2022) . - 2p.[article] Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners [Texte imprimé et/ou numérique] / R. STURNER, Auteur ; B. HOWARD, Auteur ; P. BERGMANN, Auteur ; S. ATTAR, Auteur ; L. STEWART-ARTZ, Auteur ; K. BET, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur . - 2p.
Langues : Anglais (eng)
in Molecular Autism > 13 (2022) . - 2p.
Mots-clés : Autism screening Developmental screening M-chat Q-CHAT Primary Care and its for-profit subsidiary, CHADIS, Inc. CHADIS, the web-tool used in the study was developed by Dr. Sturner and his spouse, Dr. Howard. Dr. Sturner is Director of the Center and Dr. Howard is President of CHADIS, Inc. Both are members of the Board of Directors of Center and are paid employees or consultants to both entities. The other authors have indicated they have no financial relationships relevant to this article to disclose. Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism screening is recommended at 18- and 24-month pediatric well visits. The Modified Checklist for Autism in Toddlers-Revised (M-CHAT-R) authors recommend a follow-up interview (M-CHAT-R/F) when positive. M-CHAT-R/F may be less accurate for 18-month-olds than 24-month-olds and accuracy for identification prior to two years is not known in samples that include children screening negative. Since autism symptoms may emerge gradually, ordinally scoring items based on the full range of response options, such as in the 10-item version of the Quantitative Checklist for Autism in Toddlers (Q-CHAT-10), might better capture autism signs than the dichotomous (i.e., yes/no) items in M-CHAT-R or the pass/fail scoring of Q-CHAT-10 items. The aims of this study were to determine and compare the accuracy of the M-CHAT-R/F and the Q-CHAT-10 and to describe the accuracy of the ordinally scored Q-CHAT-10 (Q-CHAT-10-O) for predicting autism in a sample of children who were screened at 18 months. METHODS: This is a community pediatrics validation study with screen positive (n?=?167) and age- and practice-matched screen negative children (n?=?241) recruited for diagnostic evaluations completed prior to 2 years old. Clinical diagnosis of autism was based on results of in-person diagnostic autism evaluations by research reliable testers blind to screening results and using the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) Toddler Module and Mullen Scales of Early Learning (MSEL) per standard guidelines. RESULTS: While the M-CHAT-R/F had higher specificity and PPV compared to M-CHAT-R, Q-CHAT-10-O showed higher sensitivity than M-CHAT-R/F and Q-CHAT-10. LIMITATIONS: Many parents declined participation and the sample is over-represented by higher educated parents. Results cannot be extended to older ages. CONCLUSIONS: Limitations of the currently recommended two-stage M-CHAT-R/F at the 18-month visit include low sensitivity with minimal balancing benefit of improved PPV from the follow-up interview. Ordinal, rather than dichotomous, scoring of autism screening items appears to be beneficial at this age. The Q-CHAT-10-O with ordinal scoring shows advantages to M-CHAT-R/F with half the number of items, no requirement for a follow-up interview, and improved sensitivity. Yet, Q-CHAT-10-O sensitivity is less than M-CHAT-R (without follow-up) and specificity is less than the two-stage procedure. Such limitations are consistent with recognition that screening needs to recur beyond this age. En ligne : http://dx.doi.org/10.1186/s13229-021-00480-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459 Accurate Autism Screening at the 18-Month Well-Child Visit Requires Different Strategies than at 24 Months / Raymond STURNER in Journal of Autism and Developmental Disorders, 47-10 (October 2017)
[article]
Titre : Accurate Autism Screening at the 18-Month Well-Child Visit Requires Different Strategies than at 24 Months Type de document : Texte imprimé et/ou numérique Auteurs : Raymond STURNER, Auteur ; Barbara HOWARD, Auteur ; Paul BERGMANN, Auteur ; Tanya MORREL, Auteur ; Rebecca LANDA, Auteur ; Kejuana WALTON, Auteur ; Danielle MARKS, Auteur Article en page(s) : p.3296-3310 Langues : Anglais (eng) Mots-clés : Autism screening Developmental screening M-CHAT Toddler development Index. décimale : PER Périodiques Résumé : Accuracy of autism screening using M-CHAT plus the follow-up interview (M-CHAT/F) for children screened positive at 18-months was compared to screening at 24-months. Formal ASD testing was criterion for a community sample of M-CHAT positive children (n?=?98), positive predictive value (PPV) was 0.40 for the M-CHAT and 0.58 for the M-CHAT/F. MCHAT/F PPV was 0.69 among children 20+ months compared to 0.36 for <20 months. Multivariate analyses incorporating data from the Ages and Stages Questionnaire, MacArthur-Bates Communicative Development Inventory, M-CHAT and M-CHAT/F results, and M-CHAT items suggest language variables carry greatest relative importance in contributing to an age-based algorithm with potential to improve PPV for toddlers <20 months to the same level as observed in older toddlers. En ligne : https://doi.org/10.1007/s10803-017-3231-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=320
in Journal of Autism and Developmental Disorders > 47-10 (October 2017) . - p.3296-3310[article] Accurate Autism Screening at the 18-Month Well-Child Visit Requires Different Strategies than at 24 Months [Texte imprimé et/ou numérique] / Raymond STURNER, Auteur ; Barbara HOWARD, Auteur ; Paul BERGMANN, Auteur ; Tanya MORREL, Auteur ; Rebecca LANDA, Auteur ; Kejuana WALTON, Auteur ; Danielle MARKS, Auteur . - p.3296-3310.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-10 (October 2017) . - p.3296-3310
Mots-clés : Autism screening Developmental screening M-CHAT Toddler development Index. décimale : PER Périodiques Résumé : Accuracy of autism screening using M-CHAT plus the follow-up interview (M-CHAT/F) for children screened positive at 18-months was compared to screening at 24-months. Formal ASD testing was criterion for a community sample of M-CHAT positive children (n?=?98), positive predictive value (PPV) was 0.40 for the M-CHAT and 0.58 for the M-CHAT/F. MCHAT/F PPV was 0.69 among children 20+ months compared to 0.36 for <20 months. Multivariate analyses incorporating data from the Ages and Stages Questionnaire, MacArthur-Bates Communicative Development Inventory, M-CHAT and M-CHAT/F results, and M-CHAT items suggest language variables carry greatest relative importance in contributing to an age-based algorithm with potential to improve PPV for toddlers <20 months to the same level as observed in older toddlers. En ligne : https://doi.org/10.1007/s10803-017-3231-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=320 Comparison of Autism Screening in Younger and Older Toddlers / Raymond STURNER in Journal of Autism and Developmental Disorders, 47-10 (October 2017)
[article]
Titre : Comparison of Autism Screening in Younger and Older Toddlers Type de document : Texte imprimé et/ou numérique Auteurs : Raymond STURNER, Auteur ; Barbara HOWARD, Auteur ; Paul BERGMANN, Auteur ; Lydia STEWART, Auteur ; Talin E. AFARIAN, Auteur Article en page(s) : p.3180-3188 Langues : Anglais (eng) Mots-clés : Autism screening M-CHAT Developmental screening Test development Index. décimale : PER Périodiques Résumé : This study examined the effect of age at completion of an autism screening test on item failure rates contrasting older (>20 months) with younger (<20 months) toddlers in a community primary care sample of 73,564 children. Items related to social development were categorized into one of three age sets per criteria from Inada et al. (Research in Autism Spectrum Disorders 4(4):605–611, 2010). Younger toddlers produced higher rates of item failure than older toddlers and items in both of the later acquired item sets had higher probability rates for failure than the earliest acquired item set (prior to 8 months). Use of the same items and the same scoring throughout the target age range for autism screening may not be the best strategy for identifying the youngest toddlers at risk for autism. En ligne : https://doi.org/10.1007/s10803-017-3230-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=319
in Journal of Autism and Developmental Disorders > 47-10 (October 2017) . - p.3180-3188[article] Comparison of Autism Screening in Younger and Older Toddlers [Texte imprimé et/ou numérique] / Raymond STURNER, Auteur ; Barbara HOWARD, Auteur ; Paul BERGMANN, Auteur ; Lydia STEWART, Auteur ; Talin E. AFARIAN, Auteur . - p.3180-3188.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-10 (October 2017) . - p.3180-3188
Mots-clés : Autism screening M-CHAT Developmental screening Test development Index. décimale : PER Périodiques Résumé : This study examined the effect of age at completion of an autism screening test on item failure rates contrasting older (>20 months) with younger (<20 months) toddlers in a community primary care sample of 73,564 children. Items related to social development were categorized into one of three age sets per criteria from Inada et al. (Research in Autism Spectrum Disorders 4(4):605–611, 2010). Younger toddlers produced higher rates of item failure than older toddlers and items in both of the later acquired item sets had higher probability rates for failure than the earliest acquired item set (prior to 8 months). Use of the same items and the same scoring throughout the target age range for autism screening may not be the best strategy for identifying the youngest toddlers at risk for autism. En ligne : https://doi.org/10.1007/s10803-017-3230-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=319 Efficacy of the ADEC in Identifying Autism Spectrum Disorder in Clinically Referred Toddlers in the US / Darren HEDLEY in Journal of Autism and Developmental Disorders, 45-8 (August 2015)
[article]
Titre : Efficacy of the ADEC in Identifying Autism Spectrum Disorder in Clinically Referred Toddlers in the US Type de document : Texte imprimé et/ou numérique Auteurs : Darren HEDLEY, Auteur ; Rose E. NEVILL, Auteur ; Yessica MONROY-MORENO, Auteur ; Natalie FIELDS, Auteur ; Jonathan WILKINS, Auteur ; Eric BUTTER, Auteur ; James A. MULICK, Auteur Année de publication : 2015 Article en page(s) : p.2337-2348 Langues : Anglais (eng) Mots-clés : ADEC Autism screening Autism Detection in Early Childhood Early detection Preschool children Reliability Validity Index. décimale : PER Périodiques Résumé : The Autism Detection in Early Childhood (ADEC) is a brief, play-based screening tool for the assessment of autism spectrum disorder (ASD) in children aged 12–36 months. We examined the psychometric properties of the ADEC in a clinical sample of toddlers (n = 114) referred to a US pediatric hospital for assessment due to concerns of developmental delay or ASD. The ADEC (cutoff = 11) returned good sensitivity (.93–.94) but poorer specificity (.62–.64) for best estimate clinical diagnosis of ASD, and compared favorably with the ADOS-2. Internal consistency was acceptable, ? = .80, and inter-rater reliability was high, ICC = .95. Results support the use of the ADEC as a clinical screen for ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2398-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263
in Journal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2337-2348[article] Efficacy of the ADEC in Identifying Autism Spectrum Disorder in Clinically Referred Toddlers in the US [Texte imprimé et/ou numérique] / Darren HEDLEY, Auteur ; Rose E. NEVILL, Auteur ; Yessica MONROY-MORENO, Auteur ; Natalie FIELDS, Auteur ; Jonathan WILKINS, Auteur ; Eric BUTTER, Auteur ; James A. MULICK, Auteur . - 2015 . - p.2337-2348.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-8 (August 2015) . - p.2337-2348
Mots-clés : ADEC Autism screening Autism Detection in Early Childhood Early detection Preschool children Reliability Validity Index. décimale : PER Périodiques Résumé : The Autism Detection in Early Childhood (ADEC) is a brief, play-based screening tool for the assessment of autism spectrum disorder (ASD) in children aged 12–36 months. We examined the psychometric properties of the ADEC in a clinical sample of toddlers (n = 114) referred to a US pediatric hospital for assessment due to concerns of developmental delay or ASD. The ADEC (cutoff = 11) returned good sensitivity (.93–.94) but poorer specificity (.62–.64) for best estimate clinical diagnosis of ASD, and compared favorably with the ADOS-2. Internal consistency was acceptable, ? = .80, and inter-rater reliability was high, ICC = .95. Results support the use of the ADEC as a clinical screen for ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2398-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=263 Engaging Pediatricians in Developmental Screening: The Effectiveness of Academic Detailing / Lisa HONIGFELD in Journal of Autism and Developmental Disorders, 42-6 (June 2012)
[article]
Titre : Engaging Pediatricians in Developmental Screening: The Effectiveness of Academic Detailing Type de document : Texte imprimé et/ou numérique Auteurs : Lisa HONIGFELD, Auteur ; Laura CHANDHOK, Auteur ; Kenneth SPIEGELMAN, Auteur Année de publication : 2012 Article en page(s) : p.1175-1182 Langues : Anglais (eng) Mots-clés : Developmental screening Autism screening Primary care Physician education Early detection of developmental disorders Index. décimale : PER Périodiques Résumé : Use of formal developmental screening tools in the pediatric medical home improves early identification of children with developmental delays and disorders, including Autism Spectrum Disorders. A pilot study evaluated the impact of an academic detailing module in which trainers visited 43 pediatric primary care practices to provide education about implementing developmental screening tools in well-child services. Attendees responded to a post presentation survey stating that they planned to implement screening in their practices. Medicaid billing data showed an increase in the state’s overall rate of screening. An audit of medical charts in five practices that received the training and five that did not showed higher screening rates in practices that received the training as well as higher rates after the training than before. These pilot study results indicate the potential of academic detailing as an effective strategy for improving rates of developmental screening. En ligne : http://dx.doi.org/10.1007/s10803-011-1344-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=157
in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1175-1182[article] Engaging Pediatricians in Developmental Screening: The Effectiveness of Academic Detailing [Texte imprimé et/ou numérique] / Lisa HONIGFELD, Auteur ; Laura CHANDHOK, Auteur ; Kenneth SPIEGELMAN, Auteur . - 2012 . - p.1175-1182.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1175-1182
Mots-clés : Developmental screening Autism screening Primary care Physician education Early detection of developmental disorders Index. décimale : PER Périodiques Résumé : Use of formal developmental screening tools in the pediatric medical home improves early identification of children with developmental delays and disorders, including Autism Spectrum Disorders. A pilot study evaluated the impact of an academic detailing module in which trainers visited 43 pediatric primary care practices to provide education about implementing developmental screening tools in well-child services. Attendees responded to a post presentation survey stating that they planned to implement screening in their practices. Medicaid billing data showed an increase in the state’s overall rate of screening. An audit of medical charts in five practices that received the training and five that did not showed higher screening rates in practices that received the training as well as higher rates after the training than before. These pilot study results indicate the potential of academic detailing as an effective strategy for improving rates of developmental screening. En ligne : http://dx.doi.org/10.1007/s10803-011-1344-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=157 Sparsifying machine learning models identify stable subsets of predictive features for behavioral detection of autism / S. LEVY in Molecular Autism, 8 (2017)
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