4 recherche sur le mot-clé 'DHEA'

Profiles of diurnal cortisol and DHEA regulation among children: Associations with maltreatment experiences, symptomatology, and positive adaptation / Fred A. ROGOSCH ; Erinn B. DUPREY ; Justin RUSSOTTI ; Dante CICCHETTI in Development and Psychopathology, 35-4 (October 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-4 (October 2023) . - p.1614-1626 Titre : Profiles of diurnal cortisol and DHEA regulation among children: Associations with maltreatment experiences, symptomatology, and positive adaptation Type de document : texte imprimé Auteurs : Fred A. ROGOSCH, Auteur ; Erinn B. DUPREY, Auteur ; Justin RUSSOTTI, Auteur ; Dante CICCHETTI, Auteur Article en page(s) : p.1614-1626 Langues : Anglais (eng) Mots-clés : child maltreatment  neuroendocrine  cortisol  DHEA  person-centered Index. décimale : PER Périodiques Résumé : Person-centered methods represent an important advance in the simultaneous examination of multiple indicators of neuroendocrine functioning and may facilitate a more nuanced understanding of the impact of child maltreatment on hypothalamic-pituitary-adrenal axis dysregulation. The aims of the present study were threefold: (a) identify naturally occurring patterns of diurnal cortisol and dehydroepiandrosterone (DHEA) regulation among a sample of N = 1,258 children with and without histories of maltreatment, (b) investigate which neuroendocrine profiles characterize children with exposure to maltreatment, and (c) examine which profiles are related to adaptive outcomes and symptomatology among children. Cortisol and DHEA were sampled three times per day (9 a.m., 12 p.m., and 4 p.m.) across 5 and 2 days, respectively. Four profiles of cortisol and DHEA regulation were identified. Among females, a pattern marked by high cortisol and low DHEA was associated with more pervasive maltreatment experiences. Furthermore, we found evidence of adaptive interpersonal resilience such that children with maltreatment exposure who evidenced this pattern of high cortisol and low DHEA were viewed as more likeable than maltreated children with other neuroendocrine patterns. Finally, results pointed to higher levels of internalizing symptoms among children who displayed a profile marked by average cortisol and high DHEA. En ligne : https://dx.doi.org/10.1017/S0954579422000335 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515 [article] Profiles of diurnal cortisol and DHEA regulation among children: Associations with maltreatment experiences, symptomatology, and positive adaptation [texte imprimé] / Fred A. ROGOSCH, Auteur ; Erinn B. DUPREY, Auteur ; Justin RUSSOTTI, Auteur ; Dante CICCHETTI, Auteur . - p.1614-1626. Langues : Anglais (eng) in Development and Psychopathology > 35-4 (October 2023) . - p.1614-1626 Mots-clés : child maltreatment  neuroendocrine  cortisol  DHEA  person-centered Index. décimale : PER Périodiques Résumé : Person-centered methods represent an important advance in the simultaneous examination of multiple indicators of neuroendocrine functioning and may facilitate a more nuanced understanding of the impact of child maltreatment on hypothalamic-pituitary-adrenal axis dysregulation. The aims of the present study were threefold: (a) identify naturally occurring patterns of diurnal cortisol and dehydroepiandrosterone (DHEA) regulation among a sample of N = 1,258 children with and without histories of maltreatment, (b) investigate which neuroendocrine profiles characterize children with exposure to maltreatment, and (c) examine which profiles are related to adaptive outcomes and symptomatology among children. Cortisol and DHEA were sampled three times per day (9 a.m., 12 p.m., and 4 p.m.) across 5 and 2 days, respectively. Four profiles of cortisol and DHEA regulation were identified. Among females, a pattern marked by high cortisol and low DHEA was associated with more pervasive maltreatment experiences. Furthermore, we found evidence of adaptive interpersonal resilience such that children with maltreatment exposure who evidenced this pattern of high cortisol and low DHEA were viewed as more likeable than maltreated children with other neuroendocrine patterns. Finally, results pointed to higher levels of internalizing symptoms among children who displayed a profile marked by average cortisol and high DHEA. En ligne : https://dx.doi.org/10.1017/S0954579422000335 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515

Caregiving quality modulates neuroendocrine and immunological markers in young children in foster care who have experienced early adversity / Vanessa REINDL in Journal of Child Psychology and Psychiatry, 63-5 (May 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.535-543 Titre : Caregiving quality modulates neuroendocrine and immunological markers in young children in foster care who have experienced early adversity Type de document : texte imprimé Auteurs : Vanessa REINDL, Auteur ; Anastasia SCHIPPERS, Auteur ; Klaus TENBROCK, Auteur ; Ann-Katrin JOB, Auteur ; Christian GERLOFF, Auteur ; Arnold LOHAUS, Auteur ; Nina HEINRICHS, Auteur ; Kerstin KONRAD, Auteur Article en page(s) : p.535-543 Langues : Anglais (eng) Mots-clés : Child, Preschool  Dehydroepiandrosterone  Foster Home Care  Humans  Hydrocortisone  Immunoglobulin A, Secretory  Longitudinal Studies  Progesterone  Saliva  Cortisol  Dhea  caregiving  children in foster care  hair steroids  longitudinal  maltreatment  sIgA Index. décimale : PER Périodiques Résumé : BACKGROUND: Early adversity is believed to alter the body's stress-response systems, putting children at increased risk for somatic and mental health problems. However, it remains unclear whether such alterations normalize under improved caregiving experiences. Thus, the goal of the present study was to investigate (a) whether children in foster care show endocrine and immunological alterations relative to children living with their biological families, (b) whether these alterations change over time spent with the foster family, and (c) whether the alterations are modulated by current caregiving experiences. METHODS: A total of 94 children in foster care and 157 biological children, aged two to seven years, took part in a longitudinal study with three assessments conducted over a 12-month study period. At the initial assessment, children lived for an average of 18 months with their current foster families. Children's cortisol, dehydroepiandrosterone (DHEA) and progesterone concentrations and cortisol/DHEA ratios were measured in scalp hair and children's secretory immunoglobulin A (sIgA) levels in saliva. Caregiving quality was assessed based on caregiver-reports and observational measures of caregiver-child interactions. RESULTS: Children in foster care had lower cortisol/DHEA ratios and higher progesterone concentrations than biological children, while no group differences were found for cortisol, DHEA or sIgA. Time spent with the current foster family did not significantly influence the child's endocrine or immunological markers. Importantly, caregiving quality modulated cortisol/DHEA ratios and sIgA concentrations: children in foster care of lower caregiving quality had lower cortisol/DHEA ratios than children in foster care of higher caregiving quality and showed decreasing, rather than increasing, sIgA concentrations across the study period. CONCLUSIONS: Our results indicate that caregiving quality in the foster family may have an important modulating effect on selected indicators of the child's stress response and could thereby mitigate the possible consequences of early childhood adversity. En ligne : http://dx.doi.org/10.1111/jcpp.13488 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 [article] Caregiving quality modulates neuroendocrine and immunological markers in young children in foster care who have experienced early adversity [texte imprimé] / Vanessa REINDL, Auteur ; Anastasia SCHIPPERS, Auteur ; Klaus TENBROCK, Auteur ; Ann-Katrin JOB, Auteur ; Christian GERLOFF, Auteur ; Arnold LOHAUS, Auteur ; Nina HEINRICHS, Auteur ; Kerstin KONRAD, Auteur . - p.535-543. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.535-543 Mots-clés : Child, Preschool  Dehydroepiandrosterone  Foster Home Care  Humans  Hydrocortisone  Immunoglobulin A, Secretory  Longitudinal Studies  Progesterone  Saliva  Cortisol  Dhea  caregiving  children in foster care  hair steroids  longitudinal  maltreatment  sIgA Index. décimale : PER Périodiques Résumé : BACKGROUND: Early adversity is believed to alter the body's stress-response systems, putting children at increased risk for somatic and mental health problems. However, it remains unclear whether such alterations normalize under improved caregiving experiences. Thus, the goal of the present study was to investigate (a) whether children in foster care show endocrine and immunological alterations relative to children living with their biological families, (b) whether these alterations change over time spent with the foster family, and (c) whether the alterations are modulated by current caregiving experiences. METHODS: A total of 94 children in foster care and 157 biological children, aged two to seven years, took part in a longitudinal study with three assessments conducted over a 12-month study period. At the initial assessment, children lived for an average of 18 months with their current foster families. Children's cortisol, dehydroepiandrosterone (DHEA) and progesterone concentrations and cortisol/DHEA ratios were measured in scalp hair and children's secretory immunoglobulin A (sIgA) levels in saliva. Caregiving quality was assessed based on caregiver-reports and observational measures of caregiver-child interactions. RESULTS: Children in foster care had lower cortisol/DHEA ratios and higher progesterone concentrations than biological children, while no group differences were found for cortisol, DHEA or sIgA. Time spent with the current foster family did not significantly influence the child's endocrine or immunological markers. Importantly, caregiving quality modulated cortisol/DHEA ratios and sIgA concentrations: children in foster care of lower caregiving quality had lower cortisol/DHEA ratios than children in foster care of higher caregiving quality and showed decreasing, rather than increasing, sIgA concentrations across the study period. CONCLUSIONS: Our results indicate that caregiving quality in the foster family may have an important modulating effect on selected indicators of the child's stress response and could thereby mitigate the possible consequences of early childhood adversity. En ligne : http://dx.doi.org/10.1111/jcpp.13488 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476

Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan / Ashley HAGAMAN ; Victoria BARANOV ; Esther O. CHUNG ; Sonia BHALOTRA ; Siham SIKANDER ; Joanna MASELKO in Development and Psychopathology, 35-4 (October 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-4 (October 2023) . - p.2086-2095 Titre : Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan Type de document : texte imprimé Auteurs : Ashley HAGAMAN, Auteur ; Victoria BARANOV, Auteur ; Esther O. CHUNG, Auteur ; Sonia BHALOTRA, Auteur ; Siham SIKANDER, Auteur ; Joanna MASELKO, Auteur Article en page(s) : p.2086-2095 Langues : Anglais (eng) Mots-clés : cortisol  DHEA  early childhood  HPA axis  mental health difficulties Index. décimale : PER Périodiques Résumé : Hypothalamic pituitary adrenal (HPA) axis activity may be a mechanism linking early adversity to child mental health difficulties. However, there is a dearth of longitudinal evidence for the association between HPA axis activity and mental health among children in low-resource contexts. The goal of this study is to examine linear and curvilinear associations between HPA axis activity during infancy and mental health difficulties in early childhood among children in rural Pakistan. Participants included 104 children (46% male) from the Bachpan study, a longitudinal cohort embedded within a maternal depression trial in Pakistan. We examined the associations between hair-derived cortisol and dehydroepiandosterone (DHEA) at 12 months old and mental health difficulties, measured with the Strengths and Difficulties Questionnaire (SDQ), at 36 months old. There was a significant quadratic association between hair cortisol and SDQ scores, with results showing a U-shaped relationship (i.e., having relatively high or low cortisol predicted increased mental health difficulties). DHEA showed a quadratic association with SDQ scores with an inverted U-shaped relationship (i.e., high and low DHEA was associated with decreased mental health difficulties). Results provide evidence of longitudinal and curvilinear effects of cortisol and DHEA during infancy on mental health difficulties in early childhood. En ligne : https://dx.doi.org/10.1017/S0954579422000773 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515 [article] Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan [texte imprimé] / Ashley HAGAMAN, Auteur ; Victoria BARANOV, Auteur ; Esther O. CHUNG, Auteur ; Sonia BHALOTRA, Auteur ; Siham SIKANDER, Auteur ; Joanna MASELKO, Auteur . - p.2086-2095. Langues : Anglais (eng) in Development and Psychopathology > 35-4 (October 2023) . - p.2086-2095 Mots-clés : cortisol  DHEA  early childhood  HPA axis  mental health difficulties Index. décimale : PER Périodiques Résumé : Hypothalamic pituitary adrenal (HPA) axis activity may be a mechanism linking early adversity to child mental health difficulties. However, there is a dearth of longitudinal evidence for the association between HPA axis activity and mental health among children in low-resource contexts. The goal of this study is to examine linear and curvilinear associations between HPA axis activity during infancy and mental health difficulties in early childhood among children in rural Pakistan. Participants included 104 children (46% male) from the Bachpan study, a longitudinal cohort embedded within a maternal depression trial in Pakistan. We examined the associations between hair-derived cortisol and dehydroepiandosterone (DHEA) at 12 months old and mental health difficulties, measured with the Strengths and Difficulties Questionnaire (SDQ), at 36 months old. There was a significant quadratic association between hair cortisol and SDQ scores, with results showing a U-shaped relationship (i.e., having relatively high or low cortisol predicted increased mental health difficulties). DHEA showed a quadratic association with SDQ scores with an inverted U-shaped relationship (i.e., high and low DHEA was associated with decreased mental health difficulties). Results provide evidence of longitudinal and curvilinear effects of cortisol and DHEA during infancy on mental health difficulties in early childhood. En ligne : https://dx.doi.org/10.1017/S0954579422000773 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515

Person-centered methods to advance developmental psychopathology / Elizabeth D. HANDLEY ; Erinn B. DUPREY ; Justin RUSSOTTI ; Rachel Y. LEVIN ; Jennifer M. WARMINGHAM in Development and Psychopathology, 36-5 (December 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-5 (December 2024) . - p.2285-2293 Titre : Person-centered methods to advance developmental psychopathology : Development and Psychopathology Type de document : texte imprimé Auteurs : Elizabeth D. HANDLEY, Auteur ; Erinn B. DUPREY, Auteur ; Justin RUSSOTTI, Auteur ; Rachel Y. LEVIN, Auteur ; Jennifer M. WARMINGHAM, Auteur Année de publication : 2024 Article en page(s) : p.2285-2293 Langues : Anglais (eng) Mots-clés : DHEA  cortisol  developmental psychopathology  maltreatment  person-centered methods Index. décimale : PER Périodiques Résumé : Dante Cicchetti?s remarkable contributions to the field of developmental psychopathology include the advancement of key principles such as the interplay of typical and atypical development, multifinality and equifinality, the dynamic processes of resilience, and the integration of multiple levels of analysis into developmental theories. In this paper we assert that person-centered data analytic methods are particularly well-suited to advancing these tenets of developmental psychopathology. We illustrate their utility with a brief novel empirical study focused on underlying patterns of childhood neuroendocrine regulation and prospective links with emerging adult functioning. Results indicate that a childhood neuroendocrine profile marked by high diurnal cortisol paired with low diurnal DHEA was uniquely associated with more adaptive functioning in emerging adulthood. We discuss these findings, and person-centered methods more broadly, within the future of developmental psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579424000282 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Person-centered methods to advance developmental psychopathology : Development and Psychopathology [texte imprimé] / Elizabeth D. HANDLEY, Auteur ; Erinn B. DUPREY, Auteur ; Justin RUSSOTTI, Auteur ; Rachel Y. LEVIN, Auteur ; Jennifer M. WARMINGHAM, Auteur . - 2024 . - p.2285-2293. Langues : Anglais (eng) in Development and Psychopathology > 36-5 (December 2024) . - p.2285-2293 Mots-clés : DHEA  cortisol  developmental psychopathology  maltreatment  person-centered methods Index. décimale : PER Périodiques Résumé : Dante Cicchetti?s remarkable contributions to the field of developmental psychopathology include the advancement of key principles such as the interplay of typical and atypical development, multifinality and equifinality, the dynamic processes of resilience, and the integration of multiple levels of analysis into developmental theories. In this paper we assert that person-centered data analytic methods are particularly well-suited to advancing these tenets of developmental psychopathology. We illustrate their utility with a brief novel empirical study focused on underlying patterns of childhood neuroendocrine regulation and prospective links with emerging adult functioning. Results indicate that a childhood neuroendocrine profile marked by high diurnal cortisol paired with low diurnal DHEA was uniquely associated with more adaptive functioning in emerging adulthood. We discuss these findings, and person-centered methods more broadly, within the future of developmental psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579424000282 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545