Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
6 recherche sur le mot-clé 'mediation analysis'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
The Role of Theory of Mind on Social Information Processing in Children With Autism Spectrum Disorders: A Mediation Analysis / Monica MAZZA in Journal of Autism and Developmental Disorders, 47-5 (May 2017)
[article]
Titre : The Role of Theory of Mind on Social Information Processing in Children With Autism Spectrum Disorders: A Mediation Analysis Type de document : Texte imprimé et/ou numérique Auteurs : Monica MAZZA, Auteur ; Melania MARIANO, Auteur ; Sara PERETTI, Auteur ; Francesco MASEDU, Auteur ; Maria Chiara PINO, Auteur ; Marco VALENTI, Auteur Article en page(s) : p.1369-1379 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD) Mediation analysis Theory of mind (ToM) Social cognition Social information processing Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorders (ASD) show significant impairments in social skills and theory of mind (ToM). The aim of this study was to evaluate ToM and social information processing abilities in 52 children with ASD compared to 55 typically developing (TD) children. A mediation analysis evaluated whether social information processing abilities can be mediated by ToM competences. In our results, children with autism showed a deficit in social skills and ToM components. The innovative results of our study applying mediation analysis demonstrate that ToM plays a key role in the development of social abilities, and the lack of ToM competences in children with autism impairs their competent social behavior. En ligne : http://dx.doi.org/10.1007/s10803-017-3069-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305
in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1369-1379[article] The Role of Theory of Mind on Social Information Processing in Children With Autism Spectrum Disorders: A Mediation Analysis [Texte imprimé et/ou numérique] / Monica MAZZA, Auteur ; Melania MARIANO, Auteur ; Sara PERETTI, Auteur ; Francesco MASEDU, Auteur ; Maria Chiara PINO, Auteur ; Marco VALENTI, Auteur . - p.1369-1379.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1369-1379
Mots-clés : Autism spectrum disorders (ASD) Mediation analysis Theory of mind (ToM) Social cognition Social information processing Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorders (ASD) show significant impairments in social skills and theory of mind (ToM). The aim of this study was to evaluate ToM and social information processing abilities in 52 children with ASD compared to 55 typically developing (TD) children. A mediation analysis evaluated whether social information processing abilities can be mediated by ToM competences. In our results, children with autism showed a deficit in social skills and ToM components. The innovative results of our study applying mediation analysis demonstrate that ToM plays a key role in the development of social abilities, and the lack of ToM competences in children with autism impairs their competent social behavior. En ligne : http://dx.doi.org/10.1007/s10803-017-3069-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 Mediators of focused psychosocial support interventions for children in low-resource humanitarian settings: analysis from an Individual Participant Dataset with 3,143 participants / Marianna PURGATO in Journal of Child Psychology and Psychiatry, 61-5 (May 2020)
[article]
Titre : Mediators of focused psychosocial support interventions for children in low-resource humanitarian settings: analysis from an Individual Participant Dataset with 3,143 participants Type de document : Texte imprimé et/ou numérique Auteurs : Marianna PURGATO, Auteur ; Federico TEDESCHI, Auteur ; Theresa S. BETANCOURT, Auteur ; Paul BOLTON, Auteur ; Chiara BONETTO, Auteur ; Chiara GASTALDON, Auteur ; James GORDON, Auteur ; Paul O'CALLAGHAN, Auteur ; Davide PAPOLA, Auteur ; Kirsi PELTONEN, Auteur ; Raija-Leena PUNAMAKI, Auteur ; Justin RICHARDS, Auteur ; Julie K. STAPLES, Auteur ; Johanna UNTERHITZENBERGER, Auteur ; Joop DE JONG, Auteur ; Mark J. D. JORDANS, Auteur ; Alden L. GROSS, Auteur ; Wietse A. TOL, Auteur ; Corrado BARBUI, Auteur Article en page(s) : p.584-593 Langues : Anglais (eng) Mots-clés : Mediation analysis children humanitarian setting individual participant data trauma Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on psychosocial interventions has been focused on the effectiveness of psychosocial interventions on mental health outcomes, without exploring how interventions achieve beneficial effects. Identifying the potential pathways through which interventions work would potentially allow further strengthening of interventions by emphasizing specific components connected with such pathways. METHODS: We conducted a preplanned mediation analysis using individual participant data from a dataset of 11 randomized controlled trials (RCTs) which compared focused psychosocial support interventions versus control conditions for children living in low- and middle-income countries (LMICs) affected by humanitarian crises. Based on an ecological resilience framework, we hypothesized that (a) coping, (b) hope, (c) social support, and (d) functional impairment mediate the relationship between intervention and outcome PTSD symptoms. A systematic search on the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PubMed, PyscARTICLES, Web of Science, and the main local LMICs databases was conducted up to August 2018. The hypotheses were tested by using individual participant data obtained from study authors of all the studies included in the systematic review. RESULTS: We included 3,143 children from 11 studies (100% of data from included studies), of which 1,877 from six studies contributed to the mediation analysis. Functional impairment was the strongest mediator for focused psychosocial interventions on PTSD (mediation coefficient -0.087, standard error 0.040). The estimated proportion of effect mediated by functional impairment, and adjusted for confounders, was 31%. CONCLUSIONS: Findings did not support the proposed mediation hypotheses for coping, hope, and social support. The mediation through functional impairment may represent unmeasured proxy measures or point to a broader mechanism that impacts self-efficacy and agency. En ligne : http://dx.doi.org/10.1111/jcpp.13151 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422
in Journal of Child Psychology and Psychiatry > 61-5 (May 2020) . - p.584-593[article] Mediators of focused psychosocial support interventions for children in low-resource humanitarian settings: analysis from an Individual Participant Dataset with 3,143 participants [Texte imprimé et/ou numérique] / Marianna PURGATO, Auteur ; Federico TEDESCHI, Auteur ; Theresa S. BETANCOURT, Auteur ; Paul BOLTON, Auteur ; Chiara BONETTO, Auteur ; Chiara GASTALDON, Auteur ; James GORDON, Auteur ; Paul O'CALLAGHAN, Auteur ; Davide PAPOLA, Auteur ; Kirsi PELTONEN, Auteur ; Raija-Leena PUNAMAKI, Auteur ; Justin RICHARDS, Auteur ; Julie K. STAPLES, Auteur ; Johanna UNTERHITZENBERGER, Auteur ; Joop DE JONG, Auteur ; Mark J. D. JORDANS, Auteur ; Alden L. GROSS, Auteur ; Wietse A. TOL, Auteur ; Corrado BARBUI, Auteur . - p.584-593.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-5 (May 2020) . - p.584-593
Mots-clés : Mediation analysis children humanitarian setting individual participant data trauma Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on psychosocial interventions has been focused on the effectiveness of psychosocial interventions on mental health outcomes, without exploring how interventions achieve beneficial effects. Identifying the potential pathways through which interventions work would potentially allow further strengthening of interventions by emphasizing specific components connected with such pathways. METHODS: We conducted a preplanned mediation analysis using individual participant data from a dataset of 11 randomized controlled trials (RCTs) which compared focused psychosocial support interventions versus control conditions for children living in low- and middle-income countries (LMICs) affected by humanitarian crises. Based on an ecological resilience framework, we hypothesized that (a) coping, (b) hope, (c) social support, and (d) functional impairment mediate the relationship between intervention and outcome PTSD symptoms. A systematic search on the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PubMed, PyscARTICLES, Web of Science, and the main local LMICs databases was conducted up to August 2018. The hypotheses were tested by using individual participant data obtained from study authors of all the studies included in the systematic review. RESULTS: We included 3,143 children from 11 studies (100% of data from included studies), of which 1,877 from six studies contributed to the mediation analysis. Functional impairment was the strongest mediator for focused psychosocial interventions on PTSD (mediation coefficient -0.087, standard error 0.040). The estimated proportion of effect mediated by functional impairment, and adjusted for confounders, was 31%. CONCLUSIONS: Findings did not support the proposed mediation hypotheses for coping, hope, and social support. The mediation through functional impairment may represent unmeasured proxy measures or point to a broader mechanism that impacts self-efficacy and agency. En ligne : http://dx.doi.org/10.1111/jcpp.13151 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422 Childhood psychopathology mediates associations between childhood adversities and multiple health risk behaviours in adolescence: analysis using the ALSPAC birth cohort / D. TROY in Journal of Child Psychology and Psychiatry, 62-9 (September 2021)
[article]
Titre : Childhood psychopathology mediates associations between childhood adversities and multiple health risk behaviours in adolescence: analysis using the ALSPAC birth cohort Type de document : Texte imprimé et/ou numérique Auteurs : D. TROY, Auteur ; A. RUSSELL, Auteur ; J. KIDGER, Auteur ; C. WRIGHT, Auteur Article en page(s) : p.1100-1109 Langues : Anglais (eng) Mots-clés : Adolescent Adult Child Health Risk Behaviors Humans Longitudinal Studies Mental Disorders/epidemiology/etiology Parents Risk Factors Self-Injurious Behavior Alspac Adverse childhood experiences UK birth cohort study adolescence mediation analysis multiple health risk behaviours psychosocial attributes structural equation modelling Index. décimale : PER Périodiques Résumé : BACKGROUND: Childhood adversity strongly predicts adolescent multiple health risk behaviours (MRBs) such as alcohol/tobacco use, self-harm and physical inactivity, and both adversities and MRBs are associated with premature mortality and several chronic health conditions that are among the leading causes of death in adults. It is therefore important to understand the relationship between adversities and MRBs and what could mediate any association. The aim of this study was to explore whether childhood psychopathology mediates associations between adversities and MRBs. METHODS: Participants were young people in the Avon Longitudinal Study of Parents and Children (ALSPAC) (N = 5,799). Using structural equation modelling, we explored the associations between adversities before 9 years and MRBs at age 16 years. We also explored potential mediating pathways through dimensional psychopathology measured by the Strength and Difficulties Questionnaire subscales at age 12 years. RESULTS: There were strong positive associations between adversities and MRBs (? .25, 95% CI 0.20, 0.31, p < .001) suggesting that each additional adversity is associated with a 0.25 increase in number of MRBs out of 13 total risk behaviours. We found robust evidence of mediating pathways from adversities through conduct problems (? .05, 95% CI 0.03, 0.06, p < .001), hyperactivity/inattention (? .02, 95% CI 0.01, 0.03, p < .001) and peer relationship problems (? -.02, 95% CI -0.03, -0.02, p < .001) to MRBs. CONCLUSIONS: Increased conduct problems and hyperactivity/inattention appear to partially explain the relationship between adversities and MRBs. Peer relationship problems also appear to reduce the association between adversities and MRBs, and further research is needed to understand how to encourage peer connectivity without increasing risk of MRBs. These results suggest that interventions aimed at reducing MRBs among those exposed to childhood adversities could focus on prevention of behavioural problems. En ligne : http://dx.doi.org/10.1111/jcpp.13379 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-9 (September 2021) . - p.1100-1109[article] Childhood psychopathology mediates associations between childhood adversities and multiple health risk behaviours in adolescence: analysis using the ALSPAC birth cohort [Texte imprimé et/ou numérique] / D. TROY, Auteur ; A. RUSSELL, Auteur ; J. KIDGER, Auteur ; C. WRIGHT, Auteur . - p.1100-1109.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-9 (September 2021) . - p.1100-1109
Mots-clés : Adolescent Adult Child Health Risk Behaviors Humans Longitudinal Studies Mental Disorders/epidemiology/etiology Parents Risk Factors Self-Injurious Behavior Alspac Adverse childhood experiences UK birth cohort study adolescence mediation analysis multiple health risk behaviours psychosocial attributes structural equation modelling Index. décimale : PER Périodiques Résumé : BACKGROUND: Childhood adversity strongly predicts adolescent multiple health risk behaviours (MRBs) such as alcohol/tobacco use, self-harm and physical inactivity, and both adversities and MRBs are associated with premature mortality and several chronic health conditions that are among the leading causes of death in adults. It is therefore important to understand the relationship between adversities and MRBs and what could mediate any association. The aim of this study was to explore whether childhood psychopathology mediates associations between adversities and MRBs. METHODS: Participants were young people in the Avon Longitudinal Study of Parents and Children (ALSPAC) (N = 5,799). Using structural equation modelling, we explored the associations between adversities before 9 years and MRBs at age 16 years. We also explored potential mediating pathways through dimensional psychopathology measured by the Strength and Difficulties Questionnaire subscales at age 12 years. RESULTS: There were strong positive associations between adversities and MRBs (? .25, 95% CI 0.20, 0.31, p < .001) suggesting that each additional adversity is associated with a 0.25 increase in number of MRBs out of 13 total risk behaviours. We found robust evidence of mediating pathways from adversities through conduct problems (? .05, 95% CI 0.03, 0.06, p < .001), hyperactivity/inattention (? .02, 95% CI 0.01, 0.03, p < .001) and peer relationship problems (? -.02, 95% CI -0.03, -0.02, p < .001) to MRBs. CONCLUSIONS: Increased conduct problems and hyperactivity/inattention appear to partially explain the relationship between adversities and MRBs. Peer relationship problems also appear to reduce the association between adversities and MRBs, and further research is needed to understand how to encourage peer connectivity without increasing risk of MRBs. These results suggest that interventions aimed at reducing MRBs among those exposed to childhood adversities could focus on prevention of behavioural problems. En ligne : http://dx.doi.org/10.1111/jcpp.13379 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 Longitudinal associations across vocabulary modalities in children with autism and typical development / Kristen BOTTEMA-BEUTEL in Autism, 23-2 (February 2019)
[article]
Titre : Longitudinal associations across vocabulary modalities in children with autism and typical development Type de document : Texte imprimé et/ou numérique Auteurs : Kristen BOTTEMA-BEUTEL, Auteur ; Tiffany G. WOYNAROSKI, Auteur ; R. LOUICK, Auteur ; E. STRINGER KEEFE, Auteur ; Linda R. WATSON, Auteur ; Paul J. YODER, Auteur Article en page(s) : p.424-435 Langues : Anglais (eng) Mots-clés : autism spectrum disorder early language joint engagement longitudinal data analysis mediation analysis vocabulary Index. décimale : PER Périodiques Résumé : We examined differences between children with autism spectrum disorder and typically developing children over an 8-month period in: (a) longitudinal associations between expressive and receptive vocabulary and (b) the extent to which caregiver utterances provided within an "optimal" engagement state mediated the pathway from early expressive to later receptive vocabulary. In total, 59 children (28-53 months at Time 1) comprised the autism spectrum disorder group and 46 children (8-24 months at Time 1) comprised the typically developing group. Groups were matched on initial vocabulary sizes. Results showed that the association between early expressive and later receptive vocabulary was moderated by group. A moderated mediation effect was also found, indicating linguistic input provided within an optimal engagement state only mediated associations for the autism spectrum disorder group. En ligne : http://dx.doi.org/10.1177/1362361317745856 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383
in Autism > 23-2 (February 2019) . - p.424-435[article] Longitudinal associations across vocabulary modalities in children with autism and typical development [Texte imprimé et/ou numérique] / Kristen BOTTEMA-BEUTEL, Auteur ; Tiffany G. WOYNAROSKI, Auteur ; R. LOUICK, Auteur ; E. STRINGER KEEFE, Auteur ; Linda R. WATSON, Auteur ; Paul J. YODER, Auteur . - p.424-435.
Langues : Anglais (eng)
in Autism > 23-2 (February 2019) . - p.424-435
Mots-clés : autism spectrum disorder early language joint engagement longitudinal data analysis mediation analysis vocabulary Index. décimale : PER Périodiques Résumé : We examined differences between children with autism spectrum disorder and typically developing children over an 8-month period in: (a) longitudinal associations between expressive and receptive vocabulary and (b) the extent to which caregiver utterances provided within an "optimal" engagement state mediated the pathway from early expressive to later receptive vocabulary. In total, 59 children (28-53 months at Time 1) comprised the autism spectrum disorder group and 46 children (8-24 months at Time 1) comprised the typically developing group. Groups were matched on initial vocabulary sizes. Results showed that the association between early expressive and later receptive vocabulary was moderated by group. A moderated mediation effect was also found, indicating linguistic input provided within an optimal engagement state only mediated associations for the autism spectrum disorder group. En ligne : http://dx.doi.org/10.1177/1362361317745856 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=383 Internalizing Symptoms Mediate the Relation Between Acute Pain and Autism in Adults / D. GARCIA-VILLAMISAR in Journal of Autism and Developmental Disorders, 49-1 (January 2019)
[article]
Titre : Internalizing Symptoms Mediate the Relation Between Acute Pain and Autism in Adults Type de document : Texte imprimé et/ou numérique Auteurs : D. GARCIA-VILLAMISAR, Auteur ; D. MOORE, Auteur ; M. GARCIA-MARTINEZ, Auteur Article en page(s) : p.270-278 Langues : Anglais (eng) Mots-clés : Asd Autism Clinical Mediation analysis Pain Index. décimale : PER Périodiques Résumé : Research on pain in autism spectrum disorder (ASD) is in its infancy, with almost nothing known about how individual differences may predicting pain response in ASD. In the present study, 45 adults (28 male, age 22-48 years) with diagnoses of autism and intellectual delay were observed during vaccination or dental cleaning and their pain behaviours coded and measures of autism symptom severity, anxiety, depression and obsessivity taken. Our findings showed that greater autism severity predicted greater pain response which was partially mediated by anxiety and depression. These data suggest that mental health symptoms are important when considering pain response in autism. Mood must therefore be considered in future research on pain in ASD as well as clinical pain management. En ligne : http://dx.doi.org/10.1007/s10803-018-3765-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377
in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.270-278[article] Internalizing Symptoms Mediate the Relation Between Acute Pain and Autism in Adults [Texte imprimé et/ou numérique] / D. GARCIA-VILLAMISAR, Auteur ; D. MOORE, Auteur ; M. GARCIA-MARTINEZ, Auteur . - p.270-278.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.270-278
Mots-clés : Asd Autism Clinical Mediation analysis Pain Index. décimale : PER Périodiques Résumé : Research on pain in autism spectrum disorder (ASD) is in its infancy, with almost nothing known about how individual differences may predicting pain response in ASD. In the present study, 45 adults (28 male, age 22-48 years) with diagnoses of autism and intellectual delay were observed during vaccination or dental cleaning and their pain behaviours coded and measures of autism symptom severity, anxiety, depression and obsessivity taken. Our findings showed that greater autism severity predicted greater pain response which was partially mediated by anxiety and depression. These data suggest that mental health symptoms are important when considering pain response in autism. Mood must therefore be considered in future research on pain in ASD as well as clinical pain management. En ligne : http://dx.doi.org/10.1007/s10803-018-3765-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377 The Role of Child Problem Behaviors in Autism Spectrum Symptoms and Parenting Stress: A Primary School-Based Study / Q. K. Y. SIU in Journal of Autism and Developmental Disorders, 49-3 (March 2019)
Permalink