Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome: A Case Series / F. VALDES in Journal of Autism and Developmental Disorders, 48-3 (March 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-3 (March 2018) . - p.947-952 Titre : Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome: A Case Series Type de document : Texte imprimé et/ou numérique Auteurs : F. VALDES, Auteur ; Christopher J. KEARY, Auteur ; J. E. MULLETT, Auteur ; M. L. PALUMBO, Auteur ; Jessica L. WAXLER, Auteur ; B. R. POBER, Auteur ; C. J. MCDOUGLE, Auteur Année de publication : 2018 Article en page(s) : p.947-952 Langues : Anglais (eng) Mots-clés : Co-morbidity  Major depressive disorder  Psychopharmacology  Psychosis  Williams syndrome Index. décimale : PER Périodiques Résumé : Descriptions of individuals with Williams syndrome (WS) and co-morbid major depressive disorder (MDD) with psychotic features have not appeared in the literature. In addition to reviewing previous reports of psychotic symptoms in persons with WS, this paper introduces clinical histories and therapeutic management strategies for three previously unreported adults with WS diagnosed with co-morbid MDD with psychotic features. Co-morbid medical disorders common in WS are highlighted with regard to safe and appropriate pharmacological treatment. The importance of assessment for co-morbid MDD with psychotic features in individuals with WS is emphasized. En ligne : https://doi.org/10.1007/s10803-017-3384-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=339 [article] Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome: A Case Series [Texte imprimé et/ou numérique] / F. VALDES, Auteur ; Christopher J. KEARY, Auteur ; J. E. MULLETT, Auteur ; M. L. PALUMBO, Auteur ; Jessica L. WAXLER, Auteur ; B. R. POBER, Auteur ; C. J. MCDOUGLE, Auteur . - 2018 . - p.947-952. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-3 (March 2018) . - p.947-952 Mots-clés : Co-morbidity  Major depressive disorder  Psychopharmacology  Psychosis  Williams syndrome Index. décimale : PER Périodiques Résumé : Descriptions of individuals with Williams syndrome (WS) and co-morbid major depressive disorder (MDD) with psychotic features have not appeared in the literature. In addition to reviewing previous reports of psychotic symptoms in persons with WS, this paper introduces clinical histories and therapeutic management strategies for three previously unreported adults with WS diagnosed with co-morbid MDD with psychotic features. Co-morbid medical disorders common in WS are highlighted with regard to safe and appropriate pharmacological treatment. The importance of assessment for co-morbid MDD with psychotic features in individuals with WS is emphasized. En ligne : https://doi.org/10.1007/s10803-017-3384-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=339

Brief Report: Suspected Cannabis-Induced Mania and Psychosis in Young Adult Males with Autism Spectrum Disorder / Majd AL-SOLEITI in Journal of Autism and Developmental Disorders, 52-9 (September 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-9 (September 2022) . - p.4164-4171 Titre : Brief Report: Suspected Cannabis-Induced Mania and Psychosis in Young Adult Males with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Majd AL-SOLEITI, Auteur ; Kayla BALAJ, Auteur ; Robyn P. THOM, Auteur ; Christopher J. MCDOUGLE, Auteur ; Christopher J. KEARY, Auteur Article en page(s) : p.4164-4171 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/etiology  Cannabis  Humans  Male  Mania  Psychotic Disorders/etiology  Retrospective Studies  Young Adult  Autism  Autism spectrum disorder  Cannabidiol  Clinical trials  Delta-9-tetrahydrocannabinol Index. décimale : PER Périodiques Résumé : There is increasing interest in investigating cannabis for behavioral symptoms in individuals with autism spectrum disorder (ASD). The potential role of dysregulated cannabinoid signaling contributing to the pathophysiology of ASD is an area of active investigation. Results from retrospective and uncontrolled trials of cannabis in subjects with ASD have been published, reporting both potential benefits and adverse effects. Here, we describe the clinical course of three young adult males with ASD who developed mania or psychosis after the consistent use of cannabidiol and delta-9-tetrahydrocannabinol. Caution should be utilized with cannabis use in individuals with ASD until large-scale, replicated randomized controlled trials demonstrating efficacy, safety and tolerability have been published. En ligne : http://dx.doi.org/10.1007/s10803-021-05254-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Brief Report: Suspected Cannabis-Induced Mania and Psychosis in Young Adult Males with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Majd AL-SOLEITI, Auteur ; Kayla BALAJ, Auteur ; Robyn P. THOM, Auteur ; Christopher J. MCDOUGLE, Auteur ; Christopher J. KEARY, Auteur . - p.4164-4171. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-9 (September 2022) . - p.4164-4171 Mots-clés : Autism Spectrum Disorder/diagnosis/etiology  Cannabis  Humans  Male  Mania  Psychotic Disorders/etiology  Retrospective Studies  Young Adult  Autism  Autism spectrum disorder  Cannabidiol  Clinical trials  Delta-9-tetrahydrocannabinol Index. décimale : PER Périodiques Résumé : There is increasing interest in investigating cannabis for behavioral symptoms in individuals with autism spectrum disorder (ASD). The potential role of dysregulated cannabinoid signaling contributing to the pathophysiology of ASD is an area of active investigation. Results from retrospective and uncontrolled trials of cannabis in subjects with ASD have been published, reporting both potential benefits and adverse effects. Here, we describe the clinical course of three young adult males with ASD who developed mania or psychosis after the consistent use of cannabidiol and delta-9-tetrahydrocannabinol. Caution should be utilized with cannabis use in individuals with ASD until large-scale, replicated randomized controlled trials demonstrating efficacy, safety and tolerability have been published. En ligne : http://dx.doi.org/10.1007/s10803-021-05254-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Buspirone for the Treatment of Generalized Anxiety Disorder in Williams Syndrome: A Case Series / Robyn P. THOM in Journal of Autism and Developmental Disorders, 50-2 (February 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-2 (February 2020) . - p.676-682 Titre : Buspirone for the Treatment of Generalized Anxiety Disorder in Williams Syndrome: A Case Series Type de document : Texte imprimé et/ou numérique Auteurs : Robyn P. THOM, Auteur ; Christopher J. KEARY, Auteur ; Jessica L. WAXLER, Auteur ; Barbara R. POBER, Auteur ; Christopher J MCDOUGLE, Auteur Article en page(s) : p.676-682 Langues : Anglais (eng) Mots-clés : Anxiety  Buspirone  Williams syndrome Index. décimale : PER Périodiques Résumé : Co-morbid anxiety disorders, including generalized anxiety disorder (GAD), are highly prevalent among individuals with Williams syndrome (WS). However, reports of the pharmacologic treatment of only a limited number of previous anxiety disorders in WS have appeared in the literature. Here, we review the case histories of three adolescents/young adults with WS and the treatment course of co-morbid GAD with buspirone. Treatment with buspirone was well-tolerated and resulted in sustained response in all three cases. Common medical disorders in WS are highlighted with regards to safe and appropriate pharmacologic treatment of GAD. Buspirone's generally benign side effect profile is a major benefit of its use for treating GAD in individuals with WS. En ligne : http://dx.doi.org/10.1007/s10803-019-04301-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416 [article] Buspirone for the Treatment of Generalized Anxiety Disorder in Williams Syndrome: A Case Series [Texte imprimé et/ou numérique] / Robyn P. THOM, Auteur ; Christopher J. KEARY, Auteur ; Jessica L. WAXLER, Auteur ; Barbara R. POBER, Auteur ; Christopher J MCDOUGLE, Auteur . - p.676-682. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-2 (February 2020) . - p.676-682 Mots-clés : Anxiety  Buspirone  Williams syndrome Index. décimale : PER Périodiques Résumé : Co-morbid anxiety disorders, including generalized anxiety disorder (GAD), are highly prevalent among individuals with Williams syndrome (WS). However, reports of the pharmacologic treatment of only a limited number of previous anxiety disorders in WS have appeared in the literature. Here, we review the case histories of three adolescents/young adults with WS and the treatment course of co-morbid GAD with buspirone. Treatment with buspirone was well-tolerated and resulted in sustained response in all three cases. Common medical disorders in WS are highlighted with regards to safe and appropriate pharmacologic treatment of GAD. Buspirone's generally benign side effect profile is a major benefit of its use for treating GAD in individuals with WS. En ligne : http://dx.doi.org/10.1007/s10803-019-04301-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416

Corpus Callosum Volume and Neurocognition in Autism / Christopher J. KEARY in Journal of Autism and Developmental Disorders, 39-6 (June 2009)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 39-6 (June 2009) . - p.834-841 Titre : Corpus Callosum Volume and Neurocognition in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Christopher J. KEARY, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur ; Matcheri S. KESHAVAN, Auteur ; Rahul BANSAL, Auteur ; Dhruman GORADIA, Auteur ; Serguei FEDOROV, Auteur Année de publication : 2009 Article en page(s) : p.834-841 Langues : Anglais (eng) Mots-clés : Autism Corpus-callosum Volume MRI Connectivity Neuropsychological-tests Index. décimale : PER Périodiques Résumé : The corpus callosum has recently been considered as an index of interhemispheric connectivity. This study applied a novel volumetric method to examine the size of the corpus callosum in 32 individuals with autism and 34 age-, gender- and IQ-matched controls and to investigate the relationship between this structure and cognitive measures linked to interhemispheric functioning. Participants with autism displayed reductions in total corpus callosum volume and in several of its subdivisions. Relationships were also observed between volumetric alterations and performance on several cognitive tests including the Tower of Hanoi test. These findings provide further evidence for anatomical alterations in the corpus callosum in autism, but warrant additional studies examining the relationship of this structure and specific measures of interhemispheric connectivity. En ligne : http://dx.doi.org/10.1007/s10803-009-0689-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=758 [article] Corpus Callosum Volume and Neurocognition in Autism [Texte imprimé et/ou numérique] / Christopher J. KEARY, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur ; Matcheri S. KESHAVAN, Auteur ; Rahul BANSAL, Auteur ; Dhruman GORADIA, Auteur ; Serguei FEDOROV, Auteur . - 2009 . - p.834-841. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 39-6 (June 2009) . - p.834-841 Mots-clés : Autism Corpus-callosum Volume MRI Connectivity Neuropsychological-tests Index. décimale : PER Périodiques Résumé : The corpus callosum has recently been considered as an index of interhemispheric connectivity. This study applied a novel volumetric method to examine the size of the corpus callosum in 32 individuals with autism and 34 age-, gender- and IQ-matched controls and to investigate the relationship between this structure and cognitive measures linked to interhemispheric functioning. Participants with autism displayed reductions in total corpus callosum volume and in several of its subdivisions. Relationships were also observed between volumetric alterations and performance on several cognitive tests including the Tower of Hanoi test. These findings provide further evidence for anatomical alterations in the corpus callosum in autism, but warrant additional studies examining the relationship of this structure and specific measures of interhemispheric connectivity. En ligne : http://dx.doi.org/10.1007/s10803-009-0689-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=758

Parent Description of Anxiety in Angelman Syndrome / Christopher J. KEARY in Journal of Autism and Developmental Disorders, 52-8 (August 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-8 (August 2022) . - p.3612-3625 Titre : Parent Description of Anxiety in Angelman Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Christopher J. KEARY, Auteur ; Jennifer E. MULLETT, Auteur ; Lisa NOWINSKI, Auteur ; Karyn WAGNER, Auteur ; Briana WALSH, Auteur ; Hannah K. SARO, Auteur ; Gillian ERHABOR, Auteur ; Ronald L. THIBERT, Auteur ; Christopher J. MCDOUGLE, Auteur ; Caitlin T. RAVICHANDRAN, Auteur Article en page(s) : p.3612-3625 Langues : Anglais (eng) Mots-clés : Angelman Syndrome/diagnosis  Anxiety  Autism Spectrum Disorder  Caregivers  Child  Humans  Parents  Psychiatric Status Rating Scales  Angelman syndrome  Hyperactivity  Irritability  Rating scale Index. décimale : PER Périodiques Résumé : Anxiety is being increasingly identified in Angelman syndrome (AS). Qualitative questions and quantitative assessments were used to evaluate for anxiety in 50 subjects with AS. In-person evaluations assessed behaviors concerning for anxiety and circumstances wherein they occurred. Caregivers completed anxiety and other behavioral rating scales. Caregiver responses were categorized and compared to items from anxiety rating scales. The most common behavioral manifestation of anxiety was "aggression." The most common circumstance was "separation from caregiver/parent." Subjects had elevated scores on anxiety, irritability and hyperactivity scales with lower mean scores among subjects with a maternal deletion. The Pediatric Anxiety Rating Scale best captured behaviors described by caregivers. Existing anxiety scales should be adapted for use in AS. En ligne : http://dx.doi.org/10.1007/s10803-021-05238-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 [article] Parent Description of Anxiety in Angelman Syndrome [Texte imprimé et/ou numérique] / Christopher J. KEARY, Auteur ; Jennifer E. MULLETT, Auteur ; Lisa NOWINSKI, Auteur ; Karyn WAGNER, Auteur ; Briana WALSH, Auteur ; Hannah K. SARO, Auteur ; Gillian ERHABOR, Auteur ; Ronald L. THIBERT, Auteur ; Christopher J. MCDOUGLE, Auteur ; Caitlin T. RAVICHANDRAN, Auteur . - p.3612-3625. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-8 (August 2022) . - p.3612-3625 Mots-clés : Angelman Syndrome/diagnosis  Anxiety  Autism Spectrum Disorder  Caregivers  Child  Humans  Parents  Psychiatric Status Rating Scales  Angelman syndrome  Hyperactivity  Irritability  Rating scale Index. décimale : PER Périodiques Résumé : Anxiety is being increasingly identified in Angelman syndrome (AS). Qualitative questions and quantitative assessments were used to evaluate for anxiety in 50 subjects with AS. In-person evaluations assessed behaviors concerning for anxiety and circumstances wherein they occurred. Caregivers completed anxiety and other behavioral rating scales. Caregiver responses were categorized and compared to items from anxiety rating scales. The most common behavioral manifestation of anxiety was "aggression." The most common circumstance was "separation from caregiver/parent." Subjects had elevated scores on anxiety, irritability and hyperactivity scales with lower mean scores among subjects with a maternal deletion. The Pediatric Anxiety Rating Scale best captured behaviors described by caregivers. Existing anxiety scales should be adapted for use in AS. En ligne : http://dx.doi.org/10.1007/s10803-021-05238-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485

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