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Brief Report: Suspected Cannabis-Induced Mania and Psychosis in Young Adult Males with Autism Spectrum Disorder / Majd AL-SOLEITI in Journal of Autism and Developmental Disorders, 52-9 (September 2022)
[article]
Titre : Brief Report: Suspected Cannabis-Induced Mania and Psychosis in Young Adult Males with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Majd AL-SOLEITI, Auteur ; Kayla BALAJ, Auteur ; Robyn P. THOM, Auteur ; Christopher J. MCDOUGLE, Auteur ; Christopher J. KEARY, Auteur Article en page(s) : p.4164-4171 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/etiology Cannabis Humans Male Mania Psychotic Disorders/etiology Retrospective Studies Young Adult Autism Autism spectrum disorder Cannabidiol Clinical trials Delta-9-tetrahydrocannabinol Index. décimale : PER Périodiques Résumé : There is increasing interest in investigating cannabis for behavioral symptoms in individuals with autism spectrum disorder (ASD). The potential role of dysregulated cannabinoid signaling contributing to the pathophysiology of ASD is an area of active investigation. Results from retrospective and uncontrolled trials of cannabis in subjects with ASD have been published, reporting both potential benefits and adverse effects. Here, we describe the clinical course of three young adult males with ASD who developed mania or psychosis after the consistent use of cannabidiol and delta-9-tetrahydrocannabinol. Caution should be utilized with cannabis use in individuals with ASD until large-scale, replicated randomized controlled trials demonstrating efficacy, safety and tolerability have been published. En ligne : http://dx.doi.org/10.1007/s10803-021-05254-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486
in Journal of Autism and Developmental Disorders > 52-9 (September 2022) . - p.4164-4171[article] Brief Report: Suspected Cannabis-Induced Mania and Psychosis in Young Adult Males with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Majd AL-SOLEITI, Auteur ; Kayla BALAJ, Auteur ; Robyn P. THOM, Auteur ; Christopher J. MCDOUGLE, Auteur ; Christopher J. KEARY, Auteur . - p.4164-4171.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-9 (September 2022) . - p.4164-4171
Mots-clés : Autism Spectrum Disorder/diagnosis/etiology Cannabis Humans Male Mania Psychotic Disorders/etiology Retrospective Studies Young Adult Autism Autism spectrum disorder Cannabidiol Clinical trials Delta-9-tetrahydrocannabinol Index. décimale : PER Périodiques Résumé : There is increasing interest in investigating cannabis for behavioral symptoms in individuals with autism spectrum disorder (ASD). The potential role of dysregulated cannabinoid signaling contributing to the pathophysiology of ASD is an area of active investigation. Results from retrospective and uncontrolled trials of cannabis in subjects with ASD have been published, reporting both potential benefits and adverse effects. Here, we describe the clinical course of three young adult males with ASD who developed mania or psychosis after the consistent use of cannabidiol and delta-9-tetrahydrocannabinol. Caution should be utilized with cannabis use in individuals with ASD until large-scale, replicated randomized controlled trials demonstrating efficacy, safety and tolerability have been published. En ligne : http://dx.doi.org/10.1007/s10803-021-05254-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 Dimensions of manic symptoms in youth: psychosocial impairment and cognitive performance in the IMAGEN sample / Argyris STRINGARIS in Journal of Child Psychology and Psychiatry, 55-12 (December 2014)
[article]
Titre : Dimensions of manic symptoms in youth: psychosocial impairment and cognitive performance in the IMAGEN sample Type de document : Texte imprimé et/ou numérique Auteurs : Argyris STRINGARIS, Auteur ; Natalie CASTELLANOS-RYAN, Auteur ; Tobias BANASCHEWSKI, Auteur ; Gareth J. BARKER, Auteur ; Arun L. W. BOKDE, Auteur ; Uli BROMBERG, Auteur ; Christian BÜCHEL, Auteur ; Mira FAUTH-BÜHLER, Auteur ; Herta FLOR, Auteur ; Vincent FROUIN, Auteur ; Juergen GALLINAT, Auteur ; Hugh GARAVAN, Auteur ; Penny GOWLAND, Auteur ; Andreas HEINZ, Auteur ; Bernd ITTERMAN, Auteur ; Claire LAWRENCE, Auteur ; Frauke NEES, Auteur ; Marie-Laure PAILLERE-MARTINOT, Auteur ; Tomas PAUS, Auteur ; Zdenka PAUSOVA, Auteur ; Marcella RIETSCHEL, Auteur ; Michael N. SMOLKA, Auteur ; Gunter SCHUMANN, Auteur ; Robert GOODMAN, Auteur ; Patricia CONROD, Auteur ; THE IMAGEN CONSORTIUM,, Auteur Article en page(s) : p.1380-1389 Langues : Anglais (eng) Mots-clés : Mania bipolar intelligence adolescents creativity Index. décimale : PER Périodiques Résumé : Background It has been reported that mania may be associated with superior cognitive performance. In this study, we test the hypothesis that manic symptoms in youth separate along two correlated dimensions and that a symptom constellation of high energy and cheerfulness is associated with superior cognitive performance. Method We studied 1755 participants of the IMAGEN study, of average age 14.4 years (SD = 0.43), 50.7% girls. Manic symptoms were assessed using the Development and Wellbeing Assessment by interviewing parents and young people. Cognition was assessed using the Wechsler Intelligence Scale For Children (WISC-IV) and a response inhibition task. Results Manic symptoms in youth formed two correlated dimensions: one termed exuberance, characterized by high energy and cheerfulness and one of undercontrol with distractibility, irritability and risk-taking behavior. Only the undercontrol, but not the exuberant dimension, was independently associated with measures of psychosocial impairment. In multivariate regression models, the exuberant, but not the undercontrolled, dimension was positively and significantly associated with verbal IQ by both parent- and self-report; conversely, the undercontrolled, but not the exuberant, dimension was associated with poor performance in a response inhibition task. Conclusions Our findings suggest that manic symptoms in youth may form dimensions with distinct correlates. The results are in keeping with previous findings about superior performance associated with mania. Further research is required to study etiological differences between these symptom dimensions and their implications for clinical practice. En ligne : http://dx.doi.org/10.1111/jcpp.12255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243
in Journal of Child Psychology and Psychiatry > 55-12 (December 2014) . - p.1380-1389[article] Dimensions of manic symptoms in youth: psychosocial impairment and cognitive performance in the IMAGEN sample [Texte imprimé et/ou numérique] / Argyris STRINGARIS, Auteur ; Natalie CASTELLANOS-RYAN, Auteur ; Tobias BANASCHEWSKI, Auteur ; Gareth J. BARKER, Auteur ; Arun L. W. BOKDE, Auteur ; Uli BROMBERG, Auteur ; Christian BÜCHEL, Auteur ; Mira FAUTH-BÜHLER, Auteur ; Herta FLOR, Auteur ; Vincent FROUIN, Auteur ; Juergen GALLINAT, Auteur ; Hugh GARAVAN, Auteur ; Penny GOWLAND, Auteur ; Andreas HEINZ, Auteur ; Bernd ITTERMAN, Auteur ; Claire LAWRENCE, Auteur ; Frauke NEES, Auteur ; Marie-Laure PAILLERE-MARTINOT, Auteur ; Tomas PAUS, Auteur ; Zdenka PAUSOVA, Auteur ; Marcella RIETSCHEL, Auteur ; Michael N. SMOLKA, Auteur ; Gunter SCHUMANN, Auteur ; Robert GOODMAN, Auteur ; Patricia CONROD, Auteur ; THE IMAGEN CONSORTIUM,, Auteur . - p.1380-1389.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-12 (December 2014) . - p.1380-1389
Mots-clés : Mania bipolar intelligence adolescents creativity Index. décimale : PER Périodiques Résumé : Background It has been reported that mania may be associated with superior cognitive performance. In this study, we test the hypothesis that manic symptoms in youth separate along two correlated dimensions and that a symptom constellation of high energy and cheerfulness is associated with superior cognitive performance. Method We studied 1755 participants of the IMAGEN study, of average age 14.4 years (SD = 0.43), 50.7% girls. Manic symptoms were assessed using the Development and Wellbeing Assessment by interviewing parents and young people. Cognition was assessed using the Wechsler Intelligence Scale For Children (WISC-IV) and a response inhibition task. Results Manic symptoms in youth formed two correlated dimensions: one termed exuberance, characterized by high energy and cheerfulness and one of undercontrol with distractibility, irritability and risk-taking behavior. Only the undercontrol, but not the exuberant dimension, was independently associated with measures of psychosocial impairment. In multivariate regression models, the exuberant, but not the undercontrolled, dimension was positively and significantly associated with verbal IQ by both parent- and self-report; conversely, the undercontrolled, but not the exuberant, dimension was associated with poor performance in a response inhibition task. Conclusions Our findings suggest that manic symptoms in youth may form dimensions with distinct correlates. The results are in keeping with previous findings about superior performance associated with mania. Further research is required to study etiological differences between these symptom dimensions and their implications for clinical practice. En ligne : http://dx.doi.org/10.1111/jcpp.12255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 Extending the ‘cross-disorder’ relevance of executive functions to dimensional neuropsychiatric traits in youth / Lauren M. MCGRATH in Journal of Child Psychology and Psychiatry, 57-4 (April 2016)
[article]
Titre : Extending the ‘cross-disorder’ relevance of executive functions to dimensional neuropsychiatric traits in youth Type de document : Texte imprimé et/ou numérique Auteurs : Lauren M. MCGRATH, Auteur ; Ellen B. BRAATEN, Auteur ; Nathan D. DOTY, Auteur ; Brian L. WILLOUGHBY, Auteur ; H. Kent WILSON, Auteur ; Ellen H. O'DONNELL, Auteur ; Mary K. COLVIN, Auteur ; Hillary L. DITMARS, Auteur ; Jessica E. BLAIS, Auteur ; Erin N. HILL, Auteur ; Aaron METZGER, Auteur ; Roy H. PERLIS, Auteur ; Erik G. WILLCUTT, Auteur ; Jordan W. SMOLLER, Auteur ; Irwin D. WALDMAN, Auteur ; Stephen V. FARAONE, Auteur ; Larry J. SEIDMAN, Auteur ; Alysa E. DOYLE, Auteur Article en page(s) : p.462-471 Langues : Anglais (eng) Mots-clés : Executive functions mania psychosis social responsiveness cross-disorder dimensional traits Index. décimale : PER Périodiques Résumé : Background Evidence that different neuropsychiatric conditions share genetic liability has increased interest in phenotypes with ‘cross-disorder’ relevance, as they may contribute to revised models of psychopathology. Cognition is a promising construct for study; yet, evidence that the same cognitive functions are impaired across different forms of psychopathology comes primarily from separate studies of individual categorical diagnoses versus controls. Given growing support for dimensional models that cut across traditional diagnostic boundaries, we aimed to determine, within a single cohort, whether performance on measures of executive functions (EFs) predicted dimensions of different psychopathological conditions known to share genetic liability. Methods Data are from 393 participants, ages 8–17, consecutively enrolled in the Longitudinal Study of Genetic Influences on Cognition (LOGIC). This project is conducting deep phenotyping and genomic analyses in youth referred for neuropsychiatric evaluation. Using structural equation modeling, we examined whether EFs predicted variation in core dimensions of the autism spectrum disorder, bipolar illness, and schizophrenia (including social responsiveness, mania/emotion regulation, and positive symptoms of psychosis, respectively). Results We modeled three cognitive factors (working memory, shifting, and executive processing speed) that loaded on a second-order EF factor. The EF factor predicted variation in our three target traits, but not in a negative control (somatization). Moreover, this EF factor was primarily associated with the overlapping (rather than unique) variance across the three outcome measures, suggesting that it related to a general increase in psychopathology symptoms across those dimensions. Conclusions Findings extend support for the relevance of cognition to neuropsychiatric conditions that share underlying genetic risk. They suggest that higher-order cognition, including EFs, relates to the dimensional spectrum of each of these disorders and not just the clinical diagnoses. Moreover, results have implications for bottom-up models linking genes, cognition, and a general psychopathology liability. En ligne : http://dx.doi.org/10.1111/jcpp.12463 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285
in Journal of Child Psychology and Psychiatry > 57-4 (April 2016) . - p.462-471[article] Extending the ‘cross-disorder’ relevance of executive functions to dimensional neuropsychiatric traits in youth [Texte imprimé et/ou numérique] / Lauren M. MCGRATH, Auteur ; Ellen B. BRAATEN, Auteur ; Nathan D. DOTY, Auteur ; Brian L. WILLOUGHBY, Auteur ; H. Kent WILSON, Auteur ; Ellen H. O'DONNELL, Auteur ; Mary K. COLVIN, Auteur ; Hillary L. DITMARS, Auteur ; Jessica E. BLAIS, Auteur ; Erin N. HILL, Auteur ; Aaron METZGER, Auteur ; Roy H. PERLIS, Auteur ; Erik G. WILLCUTT, Auteur ; Jordan W. SMOLLER, Auteur ; Irwin D. WALDMAN, Auteur ; Stephen V. FARAONE, Auteur ; Larry J. SEIDMAN, Auteur ; Alysa E. DOYLE, Auteur . - p.462-471.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-4 (April 2016) . - p.462-471
Mots-clés : Executive functions mania psychosis social responsiveness cross-disorder dimensional traits Index. décimale : PER Périodiques Résumé : Background Evidence that different neuropsychiatric conditions share genetic liability has increased interest in phenotypes with ‘cross-disorder’ relevance, as they may contribute to revised models of psychopathology. Cognition is a promising construct for study; yet, evidence that the same cognitive functions are impaired across different forms of psychopathology comes primarily from separate studies of individual categorical diagnoses versus controls. Given growing support for dimensional models that cut across traditional diagnostic boundaries, we aimed to determine, within a single cohort, whether performance on measures of executive functions (EFs) predicted dimensions of different psychopathological conditions known to share genetic liability. Methods Data are from 393 participants, ages 8–17, consecutively enrolled in the Longitudinal Study of Genetic Influences on Cognition (LOGIC). This project is conducting deep phenotyping and genomic analyses in youth referred for neuropsychiatric evaluation. Using structural equation modeling, we examined whether EFs predicted variation in core dimensions of the autism spectrum disorder, bipolar illness, and schizophrenia (including social responsiveness, mania/emotion regulation, and positive symptoms of psychosis, respectively). Results We modeled three cognitive factors (working memory, shifting, and executive processing speed) that loaded on a second-order EF factor. The EF factor predicted variation in our three target traits, but not in a negative control (somatization). Moreover, this EF factor was primarily associated with the overlapping (rather than unique) variance across the three outcome measures, suggesting that it related to a general increase in psychopathology symptoms across those dimensions. Conclusions Findings extend support for the relevance of cognition to neuropsychiatric conditions that share underlying genetic risk. They suggest that higher-order cognition, including EFs, relates to the dimensional spectrum of each of these disorders and not just the clinical diagnoses. Moreover, results have implications for bottom-up models linking genes, cognition, and a general psychopathology liability. En ligne : http://dx.doi.org/10.1111/jcpp.12463 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285 Practitioner Review: Electroconvulsive Therapy in Adolescents / Garry WALTER in Journal of Child Psychology and Psychiatry, 40-3 (March 1999)
[article]
Titre : Practitioner Review: Electroconvulsive Therapy in Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Garry WALTER, Auteur ; Joseph M. REY, Auteur ; Philip B. MITCHELL, Auteur Année de publication : 1999 Article en page(s) : p.325-334 Langues : Anglais (eng) Mots-clés : Electroconvulsive therapy adolescents major depression mania Index. décimale : PER Périodiques Résumé : There is increasing interest regarding electroconvulsive therapy (ECT) in young persons but limited information about its optimal use. This paper reviews the indications, effectiveness, and side effects of the treatment in the teenage population and their implications for everyday clinical practice. There is particular reference to factors influencing the clinician to recommend or advise against convulsive therapy, steps in the assessment of patients, and consent issues. Practical aspects of ECT administration are also examined, including treatment locale, anaesthesia, electrode position, stimulus characteristics, EEG monitoring, and use of psychotropics during and after the ECT course. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124
in Journal of Child Psychology and Psychiatry > 40-3 (March 1999) . - p.325-334[article] Practitioner Review: Electroconvulsive Therapy in Adolescents [Texte imprimé et/ou numérique] / Garry WALTER, Auteur ; Joseph M. REY, Auteur ; Philip B. MITCHELL, Auteur . - 1999 . - p.325-334.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 40-3 (March 1999) . - p.325-334
Mots-clés : Electroconvulsive therapy adolescents major depression mania Index. décimale : PER Périodiques Résumé : There is increasing interest regarding electroconvulsive therapy (ECT) in young persons but limited information about its optimal use. This paper reviews the indications, effectiveness, and side effects of the treatment in the teenage population and their implications for everyday clinical practice. There is particular reference to factors influencing the clinician to recommend or advise against convulsive therapy, steps in the assessment of patients, and consent issues. Practical aspects of ECT administration are also examined, including treatment locale, anaesthesia, electrode position, stimulus characteristics, EEG monitoring, and use of psychotropics during and after the ECT course. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=124 Practitioner Review: Long-term pharmacological treatment of pediatric bipolar disorder / Covadonga M. DIAZ-CANEJA in Journal of Child Psychology and Psychiatry, 55-9 (September 2014)
[article]
Titre : Practitioner Review: Long-term pharmacological treatment of pediatric bipolar disorder Type de document : Texte imprimé et/ou numérique Auteurs : Covadonga M. DIAZ-CANEJA, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Ana ESPLIEGO, Auteur ; Celso ARANGO, Auteur ; Dolores MORENO, Auteur Article en page(s) : p.959-980 Langues : Anglais (eng) Mots-clés : Bipolar mania maintenance mood stabilizer antipsychotic child adolescent Index. décimale : PER Périodiques Résumé : Background Although long-term treatment is a core aspect of the management of children and adolescents with bipolar disorder (BD), most clinical recommendations are based on results from short-term studies or adult data. In order to guide clinical practice, we review the efficacy and safety profile of mood stabilizers, antipsychotics, and other pharmacological strategies for the long-term treatment of BD in pediatric patients. Methods A MEDLINE, EMBASE, Cochrane and PsycInfo search (inception through November 2013) was performed to identify prospective studies longer than 12 weeks assessing the use of pharmacological strategies for the long-term treatment of BD in pediatric patients (0–18 years of age). Results Four randomized controlled trials (RCT) [three placebo-controlled (assessing aripiprazole (2) and flax oil), and one head-to-head comparison of lithium vs. divalproex], and thirteen noncontrolled studies (six open-label studies assessing lithium or anticonvulsants, five assessing second-generation antipsychotics (SGAs) and four assessing combination strategies) were included in the review. Aripiprazole has shown efficacy for relapse prevention in children with pediatric bipolar disorder (PBD) 4–9 years of age in one placebo-controlled RCT. Positive results have been reported in noncontrolled studies with quetiapine and lithium for relapse prevention, as well as with lithium, quetiapine, ziprasidone, and the combination of risperidone and divalproex or lithium for long-term symptom reduction in PBD. The most frequently reported adverse events in children and adolescents treated with lithium and anticonvulsants are gastrointestinal and neurological, whereas use of SGAs is mainly related to weight gain and sedation. Conclusion According to the limited empirical evidence, aripiprazole can be useful for relapse prevention in children with PBD. Given the lack of consistent efficacy data, clinical decision making should be based on individual clinical aspects and safety concerns. En ligne : http://dx.doi.org/10.1111/jcpp.12271 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238
in Journal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.959-980[article] Practitioner Review: Long-term pharmacological treatment of pediatric bipolar disorder [Texte imprimé et/ou numérique] / Covadonga M. DIAZ-CANEJA, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Ana ESPLIEGO, Auteur ; Celso ARANGO, Auteur ; Dolores MORENO, Auteur . - p.959-980.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.959-980
Mots-clés : Bipolar mania maintenance mood stabilizer antipsychotic child adolescent Index. décimale : PER Périodiques Résumé : Background Although long-term treatment is a core aspect of the management of children and adolescents with bipolar disorder (BD), most clinical recommendations are based on results from short-term studies or adult data. In order to guide clinical practice, we review the efficacy and safety profile of mood stabilizers, antipsychotics, and other pharmacological strategies for the long-term treatment of BD in pediatric patients. Methods A MEDLINE, EMBASE, Cochrane and PsycInfo search (inception through November 2013) was performed to identify prospective studies longer than 12 weeks assessing the use of pharmacological strategies for the long-term treatment of BD in pediatric patients (0–18 years of age). Results Four randomized controlled trials (RCT) [three placebo-controlled (assessing aripiprazole (2) and flax oil), and one head-to-head comparison of lithium vs. divalproex], and thirteen noncontrolled studies (six open-label studies assessing lithium or anticonvulsants, five assessing second-generation antipsychotics (SGAs) and four assessing combination strategies) were included in the review. Aripiprazole has shown efficacy for relapse prevention in children with pediatric bipolar disorder (PBD) 4–9 years of age in one placebo-controlled RCT. Positive results have been reported in noncontrolled studies with quetiapine and lithium for relapse prevention, as well as with lithium, quetiapine, ziprasidone, and the combination of risperidone and divalproex or lithium for long-term symptom reduction in PBD. The most frequently reported adverse events in children and adolescents treated with lithium and anticonvulsants are gastrointestinal and neurological, whereas use of SGAs is mainly related to weight gain and sedation. Conclusion According to the limited empirical evidence, aripiprazole can be useful for relapse prevention in children with PBD. Given the lack of consistent efficacy data, clinical decision making should be based on individual clinical aspects and safety concerns. En ligne : http://dx.doi.org/10.1111/jcpp.12271 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238