Autism Spectrum Disorders in Gender Dysphoric Children and Adolescents / Annelou L. C. DE VRIES in Journal of Autism and Developmental Disorders, 40-8 (August 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-8 (August 2010) . - p.930-936 Titre : Autism Spectrum Disorders in Gender Dysphoric Children and Adolescents Type de document : texte imprimé Auteurs : Annelou L. C. DE VRIES, Auteur ; Ina A. VAN BERCKELAER-ONNES, Auteur ; Ilse L.J. NOENS, Auteur ; Peggy T. COHEN-KETTENIS, Auteur ; Theo A. DORELEIJERS, Auteur Année de publication : 2010 Article en page(s) : p.930-936 Note générale : Article Open Access Langues : Anglais (eng) Mots-clés : Autism-spectrum-disorder Gender-identity-disorder Co-occurrence Incidence Index. décimale : PER Périodiques Résumé : Only case reports have described the co-occurrence of gender identity disorder (GID) and autism spectrum disorders (ASD). This study examined this co-occurrence using a systematic approach. Children and adolescents (115 boys and 89 girls, mean age 10.8, SD = 3.58) referred to a gender identity clinic received a standardized assessment during which a GID diagnosis was made and ASD suspected cases were identified. The Dutch version of the Diagnostic Interview for Social and Communication Disorders (10th rev., DISCO-10) was administered to ascertain ASD classifications. The incidence of ASD in this sample of children and adolescents was 7.8% (n = 16). Clinicians should be aware of co-occurring ASD and GID and the challenges it generates in clinical management. En ligne : http://dx.doi.org/10.1007/s10803-010-0935-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108 [article] Autism Spectrum Disorders in Gender Dysphoric Children and Adolescents [texte imprimé] / Annelou L. C. DE VRIES, Auteur ; Ina A. VAN BERCKELAER-ONNES, Auteur ; Ilse L.J. NOENS, Auteur ; Peggy T. COHEN-KETTENIS, Auteur ; Theo A. DORELEIJERS, Auteur . - 2010 . - p.930-936. Article Open Access Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-8 (August 2010) . - p.930-936 Mots-clés : Autism-spectrum-disorder Gender-identity-disorder Co-occurrence Incidence Index. décimale : PER Périodiques Résumé : Only case reports have described the co-occurrence of gender identity disorder (GID) and autism spectrum disorders (ASD). This study examined this co-occurrence using a systematic approach. Children and adolescents (115 boys and 89 girls, mean age 10.8, SD = 3.58) referred to a gender identity clinic received a standardized assessment during which a GID diagnosis was made and ASD suspected cases were identified. The Dutch version of the Diagnostic Interview for Social and Communication Disorders (10th rev., DISCO-10) was administered to ascertain ASD classifications. The incidence of ASD in this sample of children and adolescents was 7.8% (n = 16). Clinicians should be aware of co-occurring ASD and GID and the challenges it generates in clinical management. En ligne : http://dx.doi.org/10.1007/s10803-010-0935-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108

Autistic Symptoms in Children and Adolescents with Gender Dysphoria / A. I. R. VAN DER MIESEN in Journal of Autism and Developmental Disorders, 48-5 (May 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1537-1548 Titre : Autistic Symptoms in Children and Adolescents with Gender Dysphoria Type de document : texte imprimé Auteurs : A. I. R. VAN DER MIESEN, Auteur ; Annelou L. C. DE VRIES, Auteur ; T. D. STEENSMA, Auteur ; Catharina A. HARTMAN, Auteur Article en page(s) : p.1537-1548 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Co-occurrence  Comorbidity  Gender dysphoria  Gender identity disorder Index. décimale : PER Périodiques Résumé : Studies have shown an increase of symptoms of autism spectrum disorder (ASD) in gender dysphoria (GD). Various hypotheses try to explain this possible co-occurrence (e.g., a role of resistance to change, stereotyped behaviors or prenatal testosterone exposure). This study examined ASD symptoms with the Children's Social Behavior Questionnaire (CSBQ) in 490 children with GD compared to 2507 typically developing (TD) and 196 children with ASD. CSBQ total scores of the GD sample were in between scores from the TD and ASD sample. The GD sample showed elevated levels of autistic symptomatology on all subdomains, not only on stereotyped and resistance to change. Further, no gender differences and interaction effects were found on the total CSBQ, making a sole role for prenatal testosterone unlikely. En ligne : http://dx.doi.org/10.1007/s10803-017-3417-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355 [article] Autistic Symptoms in Children and Adolescents with Gender Dysphoria [texte imprimé] / A. I. R. VAN DER MIESEN, Auteur ; Annelou L. C. DE VRIES, Auteur ; T. D. STEENSMA, Auteur ; Catharina A. HARTMAN, Auteur . - p.1537-1548. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1537-1548 Mots-clés : Autism spectrum disorder  Co-occurrence  Comorbidity  Gender dysphoria  Gender identity disorder Index. décimale : PER Périodiques Résumé : Studies have shown an increase of symptoms of autism spectrum disorder (ASD) in gender dysphoria (GD). Various hypotheses try to explain this possible co-occurrence (e.g., a role of resistance to change, stereotyped behaviors or prenatal testosterone exposure). This study examined ASD symptoms with the Children's Social Behavior Questionnaire (CSBQ) in 490 children with GD compared to 2507 typically developing (TD) and 196 children with ASD. CSBQ total scores of the GD sample were in between scores from the TD and ASD sample. The GD sample showed elevated levels of autistic symptomatology on all subdomains, not only on stereotyped and resistance to change. Further, no gender differences and interaction effects were found on the total CSBQ, making a sole role for prenatal testosterone unlikely. En ligne : http://dx.doi.org/10.1007/s10803-017-3417-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355

Course of disinhibited social engagement behavior in clinically referred home-reared preschool children / F. Y. SCHEPER in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.555-565 Titre : Course of disinhibited social engagement behavior in clinically referred home-reared preschool children Type de document : texte imprimé Auteurs : F. Y. SCHEPER, Auteur ; C. R. M. GROOT, Auteur ; Annelou L. C. DE VRIES, Auteur ; Theo A. DORELEIJERS, Auteur ; L. M. C. JANSEN, Auteur ; C. SCHUENGEL, Auteur Article en page(s) : p.555-565 Langues : Anglais (eng) Mots-clés : Disinhibited social engagement  attachment  home-reared  longitudinal  preschool Index. décimale : PER Périodiques Résumé : BACKGROUND: Evidence supporting clinical relevance and persistence of disinhibited social engagement behavior (DSEB) pertains mostly to children reared in institutions and foster care. This study examined the course of DSEB in clinically referred home-reared children from early into middle childhood, and associations with neglect/emotional maltreatment, effortful control, Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Autism Spectrum Disorder. METHODS: Disinhibited social engagement behavior was examined in 124 children (82% boys, M = 4.06 years, SD = 0.89), referred for treatment of emotional and behavioral problems, by use of the Disturbances of Attachment Interview (DAI) with biological parents. Neglect and emotional maltreatment were assessed from case records and effortful control by use of the Child Behavior Questionnaire. At follow-up, on average 4 years later, DSEB was examined by use of DAI as well as two observational ratings: the Stranger at the Door procedure (SatD) and a structured home observation of stranger approach. Psychiatric disorders were assessed by means of the Kiddie-Schedule for Affective Disorders and Schizophrenia. RESULTS: Persistence of parent-reported DSEB was found in 57% (n = 27) of the children with DSEB at baseline (n = 47). Parent-reported DSEB at follow-up was significantly related to DSEB observed in the SatD (rpb = .31, p = .001) and to observed stranger approach (rs = .41, p < .001), but only stranger approach was associated with baseline DSEB. The course of DSEB was not related to neglect/emotional maltreatment, nor to the level of effortful control. There was no association between DSEB and Autism Spectrum Disorder, but course of DSEB was associated with Attention Deficit/Hyperactivity Disorder/Oppositional Defiant Disorder at follow-up (chi(2) = 13.08, p = .004). CONCLUSIONS: Although explanations for the onset and course of DSEB in home-reared children remain elusive, findings suggest that DSEB is part of a complex of clinically significant problem behaviors in referred home-reared preschool children. En ligne : http://dx.doi.org/10.1111/jcpp.12994 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 [article] Course of disinhibited social engagement behavior in clinically referred home-reared preschool children [texte imprimé] / F. Y. SCHEPER, Auteur ; C. R. M. GROOT, Auteur ; Annelou L. C. DE VRIES, Auteur ; Theo A. DORELEIJERS, Auteur ; L. M. C. JANSEN, Auteur ; C. SCHUENGEL, Auteur . - p.555-565. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.555-565 Mots-clés : Disinhibited social engagement  attachment  home-reared  longitudinal  preschool Index. décimale : PER Périodiques Résumé : BACKGROUND: Evidence supporting clinical relevance and persistence of disinhibited social engagement behavior (DSEB) pertains mostly to children reared in institutions and foster care. This study examined the course of DSEB in clinically referred home-reared children from early into middle childhood, and associations with neglect/emotional maltreatment, effortful control, Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Autism Spectrum Disorder. METHODS: Disinhibited social engagement behavior was examined in 124 children (82% boys, M = 4.06 years, SD = 0.89), referred for treatment of emotional and behavioral problems, by use of the Disturbances of Attachment Interview (DAI) with biological parents. Neglect and emotional maltreatment were assessed from case records and effortful control by use of the Child Behavior Questionnaire. At follow-up, on average 4 years later, DSEB was examined by use of DAI as well as two observational ratings: the Stranger at the Door procedure (SatD) and a structured home observation of stranger approach. Psychiatric disorders were assessed by means of the Kiddie-Schedule for Affective Disorders and Schizophrenia. RESULTS: Persistence of parent-reported DSEB was found in 57% (n = 27) of the children with DSEB at baseline (n = 47). Parent-reported DSEB at follow-up was significantly related to DSEB observed in the SatD (rpb = .31, p = .001) and to observed stranger approach (rs = .41, p < .001), but only stranger approach was associated with baseline DSEB. The course of DSEB was not related to neglect/emotional maltreatment, nor to the level of effortful control. There was no association between DSEB and Autism Spectrum Disorder, but course of DSEB was associated with Attention Deficit/Hyperactivity Disorder/Oppositional Defiant Disorder at follow-up (chi(2) = 13.08, p = .004). CONCLUSIONS: Although explanations for the onset and course of DSEB in home-reared children remain elusive, findings suggest that DSEB is part of a complex of clinically significant problem behaviors in referred home-reared preschool children. En ligne : http://dx.doi.org/10.1111/jcpp.12994 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392

Gender Variance and the Autism Spectrum: An Examination of Children Ages 6-12 Years / A. N. NABBIJOHN in Journal of Autism and Developmental Disorders, 49-4 (April 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1570-1585 Titre : Gender Variance and the Autism Spectrum: An Examination of Children Ages 6-12 Years Type de document : texte imprimé Auteurs : A. N. NABBIJOHN, Auteur ; A. I. R. VAN DER MIESEN, Auteur ; A. SANTAROSSA, Auteur ; D. PERAGINE, Auteur ; Annelou L. C. DE VRIES, Auteur ; A. POPMA, Auteur ; Meng-Chuan LAI, Auteur ; D. P. VANDERLAAN, Auteur Article en page(s) : p.1570-1585 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Gender dysphoria  Gender variance  Oppositional defiant disorder  Sensory processing disorder Index. décimale : PER Périodiques Résumé : Gender variance (GV) and autism spectrum disorder (ASD) frequently co-occur in clinical populations. We investigated GV in association with ASD characteristics in nonclinical children and in children with developmental/mental health diagnoses. In 6-12-year-olds (N = 2445; 51% birth-assigned boys), the Gender Identity Questionnaire for Children measured GV and the Children's Social Behavior Questionnaire measured six subdomains of ASD characteristics. Among nonclinical children, GV was associated with parent-reported difficulties orienting socially and stereotyped behaviors. GV was also associated with parent-reported clinical diagnoses of ASD, sensory processing disorder, and oppositional defiant disorder. These findings suggest associations between specific ASD characteristics and GV in nonclinical children. Also, childhood GV should be further examined in a range of clinical populations, including ASD individuals. En ligne : https://dx.doi.org/10.1007/s10803-018-3843-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 [article] Gender Variance and the Autism Spectrum: An Examination of Children Ages 6-12 Years [texte imprimé] / A. N. NABBIJOHN, Auteur ; A. I. R. VAN DER MIESEN, Auteur ; A. SANTAROSSA, Auteur ; D. PERAGINE, Auteur ; Annelou L. C. DE VRIES, Auteur ; A. POPMA, Auteur ; Meng-Chuan LAI, Auteur ; D. P. VANDERLAAN, Auteur . - p.1570-1585. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1570-1585 Mots-clés : Autism spectrum disorder  Gender dysphoria  Gender variance  Oppositional defiant disorder  Sensory processing disorder Index. décimale : PER Périodiques Résumé : Gender variance (GV) and autism spectrum disorder (ASD) frequently co-occur in clinical populations. We investigated GV in association with ASD characteristics in nonclinical children and in children with developmental/mental health diagnoses. In 6-12-year-olds (N = 2445; 51% birth-assigned boys), the Gender Identity Questionnaire for Children measured GV and the Children's Social Behavior Questionnaire measured six subdomains of ASD characteristics. Among nonclinical children, GV was associated with parent-reported difficulties orienting socially and stereotyped behaviors. GV was also associated with parent-reported clinical diagnoses of ASD, sensory processing disorder, and oppositional defiant disorder. These findings suggest associations between specific ASD characteristics and GV in nonclinical children. Also, childhood GV should be further examined in a range of clinical populations, including ASD individuals. En ligne : https://dx.doi.org/10.1007/s10803-018-3843-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388

Psychiatric comorbidity in gender dysphoric adolescents / Annelou L. C. DE VRIES in Journal of Child Psychology and Psychiatry, 52-11 (November 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-11 (November 2011) . - p.1195-1202 Titre : Psychiatric comorbidity in gender dysphoric adolescents Type de document : texte imprimé Auteurs : Annelou L. C. DE VRIES, Auteur ; Theo A. DORELEIJERS, Auteur ; Thomas D. STEENSMA, Auteur ; Peggy T. COHEN-KETTENIS, Auteur Année de publication : 2011 Article en page(s) : p.1195-1202 Langues : Anglais (eng) Mots-clés : Gender identity disorder  gender dysphoria  adolescents  psychiatric comorbidity  puberty suppression  cross-sex hormones Index. décimale : PER Périodiques Résumé : Background:  This study examined psychiatric comorbidity in adolescents with a gender identity disorder (GID). We focused on its relation to gender, type of GID diagnosis and eligibility for medical interventions (puberty suppression and cross-sex hormones). Methods:  To ascertain DSM-IV diagnoses, the Diagnostic Interview Schedule for Children (DISC) was administered to parents of 105 gender dysphoric adolescents. Results:  67.6% had no concurrent psychiatric disorder. Anxiety disorders occurred in 21%, mood disorders in 12.4% and disruptive disorders in 11.4% of the adolescents. Compared with natal females (n = 52), natal males (n = 53) suffered more often from two or more comorbid diagnoses (22.6% vs. 7.7%, p = .03), mood disorders (20.8% vs. 3.8%, p = .008) and social anxiety disorder (15.1% vs. 3.8%, p = .049). Adolescents with GID considered to be ‘delayed eligible’ for medical treatment were older [15.6 years (SD = 1.6) vs. 14.1 years (SD = 2.2), p = .001], their intelligence was lower [91.6 (SD = 12.4) vs. 99.1 (SD = 12.8), p = .011] and a lower percentage was living with both parents (23% vs. 64%, p < .001). Although the two groups did not differ in the prevalence of psychiatric comorbidity, the respective odds ratios (‘delayed eligible’ adolescents vs. ‘immediately eligible’ adolescents) were >1.0 for all psychiatric diagnoses except specific phobia. Conclusions:  Despite the suffering resulting from the incongruence between experienced and assigned gender at the start of puberty, the majority of gender dysphoric adolescents do not have co-occurring psychiatric problems. Delayed eligibility for medical interventions is associated with psychiatric comorbidity although other factors are of importance as well. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02426.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=145 [article] Psychiatric comorbidity in gender dysphoric adolescents [texte imprimé] / Annelou L. C. DE VRIES, Auteur ; Theo A. DORELEIJERS, Auteur ; Thomas D. STEENSMA, Auteur ; Peggy T. COHEN-KETTENIS, Auteur . - 2011 . - p.1195-1202. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-11 (November 2011) . - p.1195-1202 Mots-clés : Gender identity disorder  gender dysphoria  adolescents  psychiatric comorbidity  puberty suppression  cross-sex hormones Index. décimale : PER Périodiques Résumé : Background:  This study examined psychiatric comorbidity in adolescents with a gender identity disorder (GID). We focused on its relation to gender, type of GID diagnosis and eligibility for medical interventions (puberty suppression and cross-sex hormones). Methods:  To ascertain DSM-IV diagnoses, the Diagnostic Interview Schedule for Children (DISC) was administered to parents of 105 gender dysphoric adolescents. Results:  67.6% had no concurrent psychiatric disorder. Anxiety disorders occurred in 21%, mood disorders in 12.4% and disruptive disorders in 11.4% of the adolescents. Compared with natal females (n = 52), natal males (n = 53) suffered more often from two or more comorbid diagnoses (22.6% vs. 7.7%, p = .03), mood disorders (20.8% vs. 3.8%, p = .008) and social anxiety disorder (15.1% vs. 3.8%, p = .049). Adolescents with GID considered to be ‘delayed eligible’ for medical treatment were older [15.6 years (SD = 1.6) vs. 14.1 years (SD = 2.2), p = .001], their intelligence was lower [91.6 (SD = 12.4) vs. 99.1 (SD = 12.8), p = .011] and a lower percentage was living with both parents (23% vs. 64%, p < .001). Although the two groups did not differ in the prevalence of psychiatric comorbidity, the respective odds ratios (‘delayed eligible’ adolescents vs. ‘immediately eligible’ adolescents) were >1.0 for all psychiatric diagnoses except specific phobia. Conclusions:  Despite the suffering resulting from the incongruence between experienced and assigned gender at the start of puberty, the majority of gender dysphoric adolescents do not have co-occurring psychiatric problems. Delayed eligibility for medical interventions is associated with psychiatric comorbidity although other factors are of importance as well. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02426.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=145

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