Démarrer l’acquisition de la syntaxe / Elodie CAUVET in Rééducation Orthophonique, 244 (Décembre 2010)

Public ISBD [article]  inRééducation Orthophonique > 244 (Décembre 2010) . - p.95-109 Titre : Démarrer l’acquisition de la syntaxe Type de document : Texte imprimé et/ou numérique Auteurs : Elodie CAUVET, Auteur ; Perrine BRUSINI, Auteur ; Anne-Caroline FIEVET, Auteur ; Séverine MILLOTTE, Auteur ; Anne CHRISTOPHE, Auteur Année de publication : 2010 Article en page(s) : p.95-109 Langues : Français (fre) Mots-clés : acquisition du langage  nourrissons  prosodie de phrase  mots grammaticaux Index. décimale : PER Périodiques Résumé : Dans le domaine de l’acquisition du langage, on appelle ‘problème d’initialisation’ une situation où des connaissances d’un domaine sont nécessaires pour acquérir des connaissances dans un autre domaine (par exemple, l’accès aux mots et à leur signification devrait permettre l’apprentissage de la syntaxe, mais l’apprentissage du sens des mots serait facilité si les enfants avaient accès à certains aspects de la structure syntaxique des phrases, (Gleitman, 1990). L’hypothèse d’initialisation phonologique repose sur l’idée que les nourrissons pourraient démarrer leur acquisition du langage en exploitant de l’information qui peut être obtenue grâce à une analyse de surface du signal acoustique (Morgan & Demuth, 1996b). Dans cet article, nous allons nous centrer sur la manière dont la prosodie des phrases et les mots grammaticaux interagissent lors de l’acquisition précoce du langage. Ces deux sources d’informations, qui sont accessibles dans le signal de parole, pourraient permettre aux jeunes enfants de construire une ébauche de structure syntaxique, le ‘squelette syntaxique’, qui serait suffisant pour faciliter l’apprentissage du sens des mots et de la syntaxe. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=116 [article] Démarrer l’acquisition de la syntaxe [Texte imprimé et/ou numérique] / Elodie CAUVET, Auteur ; Perrine BRUSINI, Auteur ; Anne-Caroline FIEVET, Auteur ; Séverine MILLOTTE, Auteur ; Anne CHRISTOPHE, Auteur . - 2010 . - p.95-109. Langues : Français (fre) in Rééducation Orthophonique > 244 (Décembre 2010) . - p.95-109 Mots-clés : acquisition du langage  nourrissons  prosodie de phrase  mots grammaticaux Index. décimale : PER Périodiques Résumé : Dans le domaine de l’acquisition du langage, on appelle ‘problème d’initialisation’ une situation où des connaissances d’un domaine sont nécessaires pour acquérir des connaissances dans un autre domaine (par exemple, l’accès aux mots et à leur signification devrait permettre l’apprentissage de la syntaxe, mais l’apprentissage du sens des mots serait facilité si les enfants avaient accès à certains aspects de la structure syntaxique des phrases, (Gleitman, 1990). L’hypothèse d’initialisation phonologique repose sur l’idée que les nourrissons pourraient démarrer leur acquisition du langage en exploitant de l’information qui peut être obtenue grâce à une analyse de surface du signal acoustique (Morgan & Demuth, 1996b). Dans cet article, nous allons nous centrer sur la manière dont la prosodie des phrases et les mots grammaticaux interagissent lors de l’acquisition précoce du langage. Ces deux sources d’informations, qui sont accessibles dans le signal de parole, pourraient permettre aux jeunes enfants de construire une ébauche de structure syntaxique, le ‘squelette syntaxique’, qui serait suffisant pour faciliter l’apprentissage du sens des mots et de la syntaxe. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=116

EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort / J. ISAKSSON in Molecular Autism, 9 (2018)  

Public ISBD [article]  inMolecular Autism > 9 (2018) . - 26p. Titre : EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort Type de document : Texte imprimé et/ou numérique Auteurs : J. ISAKSSON, Auteur ; K. TAMMIMIES, Auteur ; J. NEUFELD, Auteur ; Elodie CAUVET, Auteur ; K. LUNDIN, Auteur ; Jan K. BUITELAAR, Auteur ; E. LOTH, Auteur ; D. G. M. MURPHY, Auteur ; W. SPOOREN, Auteur ; Sven BÖLTE, Auteur Article en page(s) : 26p. Langues : Anglais (eng) Mots-clés : Adolescent  Autistic Disorder/diagnosis/epidemiology/genetics  Child  Cohort Studies  Europe  Female  Humans  Longitudinal Studies  Male  Phenotype  Twins, Dizygotic/statistics & numerical data  Twins, Monozygotic/statistics & numerical data  adhd  Autism spectrum disorder  Biomarkers  Brain  Cognition  Genetics  Intervention  Twins Index. décimale : PER Périodiques Résumé : EU-AIMS is the largest European research program aiming to identify stratification biomarkers and novel interventions for autism spectrum disorder (ASD). Within the program, the Longitudinal European Autism Project (LEAP) has recruited and comprehensively phenotyped a rare sample of 76 monozygotic and dizygotic twins, discordant, or concordant for ASD plus 30 typically developing twins. The aim of this letter is to complete previous descriptions of the LEAP case-control sample, clinically characterize, and investigate the suitability of the sample for ASD twin-control analyses purposes and share some 'lessons learnt.' Among the twins, a diagnosis of ASD is associated with increased symptom levels of ADHD, higher rates of intellectual disability, and lower family income. For the future, we conclude that the LEAP twin cohort offers multiple options for analyses of genetic and shared and non-shared environmental factors to generate new hypotheses for the larger cohort of LEAP singletons, but particularly cross-validate and refine evidence from it. En ligne : https://dx.doi.org/10.1186/s13229-018-0212-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort [Texte imprimé et/ou numérique] / J. ISAKSSON, Auteur ; K. TAMMIMIES, Auteur ; J. NEUFELD, Auteur ; Elodie CAUVET, Auteur ; K. LUNDIN, Auteur ; Jan K. BUITELAAR, Auteur ; E. LOTH, Auteur ; D. G. M. MURPHY, Auteur ; W. SPOOREN, Auteur ; Sven BÖLTE, Auteur . - 26p. Langues : Anglais (eng) in Molecular Autism > 9 (2018) . - 26p. Mots-clés : Adolescent  Autistic Disorder/diagnosis/epidemiology/genetics  Child  Cohort Studies  Europe  Female  Humans  Longitudinal Studies  Male  Phenotype  Twins, Dizygotic/statistics & numerical data  Twins, Monozygotic/statistics & numerical data  adhd  Autism spectrum disorder  Biomarkers  Brain  Cognition  Genetics  Intervention  Twins Index. décimale : PER Périodiques Résumé : EU-AIMS is the largest European research program aiming to identify stratification biomarkers and novel interventions for autism spectrum disorder (ASD). Within the program, the Longitudinal European Autism Project (LEAP) has recruited and comprehensively phenotyped a rare sample of 76 monozygotic and dizygotic twins, discordant, or concordant for ASD plus 30 typically developing twins. The aim of this letter is to complete previous descriptions of the LEAP case-control sample, clinically characterize, and investigate the suitability of the sample for ASD twin-control analyses purposes and share some 'lessons learnt.' Among the twins, a diagnosis of ASD is associated with increased symptom levels of ADHD, higher rates of intellectual disability, and lower family income. For the future, we conclude that the LEAP twin cohort offers multiple options for analyses of genetic and shared and non-shared environmental factors to generate new hypotheses for the larger cohort of LEAP singletons, but particularly cross-validate and refine evidence from it. En ligne : https://dx.doi.org/10.1186/s13229-018-0212-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

Global and local visual processing in autism - a co-twin-control study / J. NEUFELD in Journal of Child Psychology and Psychiatry, 61-4 (April 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-4 (April 2020) . - p.470-479 Titre : Global and local visual processing in autism - a co-twin-control study Type de document : Texte imprimé et/ou numérique Auteurs : J. NEUFELD, Auteur ; A. HAGSTROM, Auteur ; A. VAN'T WESTEINDE, Auteur ; K. LUNDIN, Auteur ; Elodie CAUVET, Auteur ; C. WILLFORS, Auteur ; J. ISAKSSON, Auteur ; P. LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.470-479 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  central coherence  co-twin-control design  detail focus  global/local visual processing Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism Spectrum Disorder (ASD) is associated with altered global and local visual processing. However, the nature of these alterations remains controversial, with contradictory findings and notions ranging from a reduced drive to integrate information into a coherent 'gestalt' ("weak central coherence" = WCC) to an enhanced perceptual functioning (EPF) in local processing. METHODS: This study assessed the association between autism and global/local visual processing, using a large sample of monozygotic (MZ) and dizygotic (DZ) twins (N = 290, 48% females, age = 8-31 years). The Fragmented Pictures Test (FPT) assessed global processing, whereas local processing was estimated with the Embedded Figures Test (EFT) and the Block Design Test (BDT). Autism was assessed both categorically (clinical diagnosis), and dimensionally (autistic traits). Associations between visual tasks and autism were estimated both across the cohort and within-twin pairs where all factors shared between twins are implicitly controlled. RESULTS: Clinical diagnosis and autistic traits predicted a need for more visual information for gestalt processing in the FPT across the cohort. For clinical diagnosis, this association remained within-pairs and at trend-level even within MZ twin pairs alone. ASD and higher autistic traits predicted lower EFT and BDT performance across the cohort, but these associations were lost within-pairs. CONCLUSIONS: In line with the WCC account, our findings indicate an association between autism and reduced global visual processing in children, adolescents and young adults (but no evidence for EPF). Observing a similar association within MZ twins suggests a non-shared environmental contribution. En ligne : http://dx.doi.org/10.1111/jcpp.13120 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421 [article] Global and local visual processing in autism - a co-twin-control study [Texte imprimé et/ou numérique] / J. NEUFELD, Auteur ; A. HAGSTROM, Auteur ; A. VAN'T WESTEINDE, Auteur ; K. LUNDIN, Auteur ; Elodie CAUVET, Auteur ; C. WILLFORS, Auteur ; J. ISAKSSON, Auteur ; P. LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur . - p.470-479. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-4 (April 2020) . - p.470-479 Mots-clés : Autism Spectrum Disorder  central coherence  co-twin-control design  detail focus  global/local visual processing Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism Spectrum Disorder (ASD) is associated with altered global and local visual processing. However, the nature of these alterations remains controversial, with contradictory findings and notions ranging from a reduced drive to integrate information into a coherent 'gestalt' ("weak central coherence" = WCC) to an enhanced perceptual functioning (EPF) in local processing. METHODS: This study assessed the association between autism and global/local visual processing, using a large sample of monozygotic (MZ) and dizygotic (DZ) twins (N = 290, 48% females, age = 8-31 years). The Fragmented Pictures Test (FPT) assessed global processing, whereas local processing was estimated with the Embedded Figures Test (EFT) and the Block Design Test (BDT). Autism was assessed both categorically (clinical diagnosis), and dimensionally (autistic traits). Associations between visual tasks and autism were estimated both across the cohort and within-twin pairs where all factors shared between twins are implicitly controlled. RESULTS: Clinical diagnosis and autistic traits predicted a need for more visual information for gestalt processing in the FPT across the cohort. For clinical diagnosis, this association remained within-pairs and at trend-level even within MZ twin pairs alone. ASD and higher autistic traits predicted lower EFT and BDT performance across the cohort, but these associations were lost within-pairs. CONCLUSIONS: In line with the WCC account, our findings indicate an association between autism and reduced global visual processing in children, adolescents and young adults (but no evidence for EPF). Observing a similar association within MZ twins suggests a non-shared environmental contribution. En ligne : http://dx.doi.org/10.1111/jcpp.13120 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421

Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism / A. VAN'T WESTEINDE in Molecular Autism, 11 (2020)  

Public ISBD [article]  inMolecular Autism > 11 (2020) . - 1 p. Titre : Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism Type de document : Texte imprimé et/ou numérique Auteurs : A. VAN'T WESTEINDE, Auteur ; Elodie CAUVET, Auteur ; R. TORO, Auteur ; R. KUJA-HALKOLA, Auteur ; J. NEUFELD, Auteur ; K. MEVEL, Auteur ; Sven BÖLTE, Auteur Article en page(s) : 1 p. Langues : Anglais (eng) Mots-clés : Autism  Neuroanatomy  Repetitive behaviors  Sex differences  Twins Index. décimale : PER Périodiques Résumé : Background: Females with autism spectrum disorder have been reported to exhibit fewer and less severe restricted and repetitive behaviors and interests compared to males. This difference might indicate sex-specific alterations of brain networks involved in autism symptom domains, especially within cortico-striatal and sensory integration networks. This study used a well-controlled twin design to examine sex differences in brain anatomy in relation to repetitive behaviors. Methods: In 75 twin pairs (n = 150, 62 females, 88 males) enriched for autism spectrum disorder (n = 32), and other neurodevelopmental disorders (n = 32), we explored the association of restricted and repetitive behaviors and interests-operationalized by the Autism Diagnostic Interview-Revised (C domain) and the Social Responsiveness Scale-2 (Restricted Interests and Repetitive Behavior subscale)-with cortical volume, surface area and thickness of neocortical, sub-cortical, and cerebellar networks. Results: Co-twin control analyses revealed within-pair associations between RRBI symptoms and increased thickness of the right intraparietal sulcus and reduced volume of the right orbital gyrus in females only, even though the mean number of RRBIs did not differ between the sexes. In a sub-sample of ASD-discordant pairs, increased thickness in association with RRBIs was found exclusively in females in the orbitofrontal regions, superior frontal gyrus, and intraparietal sulcus, while in males RRBIs tended to be associated with increased volume of the bilateral pallidum. Limitations: However, due to a small sample size and the small difference in RRBI symptoms within pairs, the results of this exploratory study need to be interpreted with caution. Conclusions: Our findings suggest that structural alterations of fronto-parietal networks in association with RRBIs are found mostly in females, while striatal networks are more affected in males. These results endorse the importance of investigating sex differences in the neurobiology of autism symptoms, and indicate different etiological pathways underlying restricted and repetitive behaviors and interests in females and males. En ligne : http://dx.doi.org/10.1186/s13229-019-0309-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 [article] Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism [Texte imprimé et/ou numérique] / A. VAN'T WESTEINDE, Auteur ; Elodie CAUVET, Auteur ; R. TORO, Auteur ; R. KUJA-HALKOLA, Auteur ; J. NEUFELD, Auteur ; K. MEVEL, Auteur ; Sven BÖLTE, Auteur . - 1 p. Langues : Anglais (eng) in Molecular Autism > 11 (2020) . - 1 p. Mots-clés : Autism  Neuroanatomy  Repetitive behaviors  Sex differences  Twins Index. décimale : PER Périodiques Résumé : Background: Females with autism spectrum disorder have been reported to exhibit fewer and less severe restricted and repetitive behaviors and interests compared to males. This difference might indicate sex-specific alterations of brain networks involved in autism symptom domains, especially within cortico-striatal and sensory integration networks. This study used a well-controlled twin design to examine sex differences in brain anatomy in relation to repetitive behaviors. Methods: In 75 twin pairs (n = 150, 62 females, 88 males) enriched for autism spectrum disorder (n = 32), and other neurodevelopmental disorders (n = 32), we explored the association of restricted and repetitive behaviors and interests-operationalized by the Autism Diagnostic Interview-Revised (C domain) and the Social Responsiveness Scale-2 (Restricted Interests and Repetitive Behavior subscale)-with cortical volume, surface area and thickness of neocortical, sub-cortical, and cerebellar networks. Results: Co-twin control analyses revealed within-pair associations between RRBI symptoms and increased thickness of the right intraparietal sulcus and reduced volume of the right orbital gyrus in females only, even though the mean number of RRBIs did not differ between the sexes. In a sub-sample of ASD-discordant pairs, increased thickness in association with RRBIs was found exclusively in females in the orbitofrontal regions, superior frontal gyrus, and intraparietal sulcus, while in males RRBIs tended to be associated with increased volume of the bilateral pallidum. Limitations: However, due to a small sample size and the small difference in RRBI symptoms within pairs, the results of this exploratory study need to be interpreted with caution. Conclusions: Our findings suggest that structural alterations of fronto-parietal networks in association with RRBIs are found mostly in females, while striatal networks are more affected in males. These results endorse the importance of investigating sex differences in the neurobiology of autism symptoms, and indicate different etiological pathways underlying restricted and repetitive behaviors and interests in females and males. En ligne : http://dx.doi.org/10.1186/s13229-019-0309-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414

Social Cognition in Autism and Other Neurodevelopmental Disorders: A Co-twin Control Study / J. ISAKSSON in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2838-2848 Titre : Social Cognition in Autism and Other Neurodevelopmental Disorders: A Co-twin Control Study Type de document : Texte imprimé et/ou numérique Auteurs : J. ISAKSSON, Auteur ; A. VAN'T WESTEINDE, Auteur ; Elodie CAUVET, Auteur ; R. KUJA-HALKOLA, Auteur ; K. LUNDIN, Auteur ; J. NEUFELD, Auteur ; C. WILLFORS, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.2838-2848 Langues : Anglais (eng) Mots-clés : Adhd  Autism spectrum disorder  Movie for the assessment of social cognition  Ratss  Twins Index. décimale : PER Périodiques Résumé : Alterations in social cognition (SC) are hypothesized to underlie social communication and interaction challenges in autism spectrum disorder (ASD). The aetiological underpinnings driving this association remain unclear. We examined SC in 196 twins with ASD, other neurodevelopmental disorders or typical development using the naturalistic Movie for the Assessment of Social Cognition. Autism and its severity were assessed with the Autism Diagnostic Observation Schedule-2, and autistic traits with the Social Responsiveness Scale-2. Using within twin-pair regression models, controlling for age, sex, IQ, and unmeasured familial confounders such as genetic background and shared-environment, SC correlated with ASD diagnosis, autism severity, and autistic traits. Our findings highlight the importance of SC alterations in autism and suggest a non-shared environmental impact on the association. En ligne : http://dx.doi.org/10.1007/s10803-019-04001-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Social Cognition in Autism and Other Neurodevelopmental Disorders: A Co-twin Control Study [Texte imprimé et/ou numérique] / J. ISAKSSON, Auteur ; A. VAN'T WESTEINDE, Auteur ; Elodie CAUVET, Auteur ; R. KUJA-HALKOLA, Auteur ; K. LUNDIN, Auteur ; J. NEUFELD, Auteur ; C. WILLFORS, Auteur ; Sven BÖLTE, Auteur . - p.2838-2848. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2838-2848 Mots-clés : Adhd  Autism spectrum disorder  Movie for the assessment of social cognition  Ratss  Twins Index. décimale : PER Périodiques Résumé : Alterations in social cognition (SC) are hypothesized to underlie social communication and interaction challenges in autism spectrum disorder (ASD). The aetiological underpinnings driving this association remain unclear. We examined SC in 196 twins with ASD, other neurodevelopmental disorders or typical development using the naturalistic Movie for the Assessment of Social Cognition. Autism and its severity were assessed with the Autism Diagnostic Observation Schedule-2, and autistic traits with the Social Responsiveness Scale-2. Using within twin-pair regression models, controlling for age, sex, IQ, and unmeasured familial confounders such as genetic background and shared-environment, SC correlated with ASD diagnosis, autism severity, and autistic traits. Our findings highlight the importance of SC alterations in autism and suggest a non-shared environmental impact on the association. En ligne : http://dx.doi.org/10.1007/s10803-019-04001-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

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