Dépouillements

Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority / Alycia K. HALLADAY in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-5 Titre : Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority Type de document : Texte imprimé et/ou numérique Auteurs : Alycia K. HALLADAY, Auteur ; Somer L. BISHOP, Auteur ; John N. CONSTANTINO, Auteur ; Amy M. DANIELS, Auteur ; Kathleen KOENIG, Auteur ; Kate PALMER, Auteur ; Daniel MESSINGER, Auteur ; Kevin A. PELPHREY, Auteur ; Stephan J. SANDERS, Auteur ; Alison Tepper SINGER, Auteur ; Julie LOUNDS TAYLOR, Auteur ; Peter SZATMARI, Auteur Article en page(s) : p.1-5 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : One of the most consistent findings in autism spectrum disorder (ASD) research is a higher rate of ASD diagnosis in males than females. Despite this, remarkably little research has focused on the reasons for this disparity. Better understanding of this sex difference could lead to major advancements in the prevention or treatment of ASD in both males and females. In October of 2014, Autism Speaks and the Autism Science Foundation co-organized a meeting that brought together almost 60 clinicians, researchers, parents, and self-identified autistic individuals. Discussion at the meeting is summarized here with recommendations on directions of future research endeavors. En ligne : http://dx.doi.org/10.1186/s13229-015-0019-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority [Texte imprimé et/ou numérique] / Alycia K. HALLADAY, Auteur ; Somer L. BISHOP, Auteur ; John N. CONSTANTINO, Auteur ; Amy M. DANIELS, Auteur ; Kathleen KOENIG, Auteur ; Kate PALMER, Auteur ; Daniel MESSINGER, Auteur ; Kevin A. PELPHREY, Auteur ; Stephan J. SANDERS, Auteur ; Alison Tepper SINGER, Auteur ; Julie LOUNDS TAYLOR, Auteur ; Peter SZATMARI, Auteur . - p.1-5. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-5 Index. décimale : PER Périodiques Résumé : One of the most consistent findings in autism spectrum disorder (ASD) research is a higher rate of ASD diagnosis in males than females. Despite this, remarkably little research has focused on the reasons for this disparity. Better understanding of this sex difference could lead to major advancements in the prevention or treatment of ASD in both males and females. In October of 2014, Autism Speaks and the Autism Science Foundation co-organized a meeting that brought together almost 60 clinicians, researchers, parents, and self-identified autistic individuals. Discussion at the meeting is summarized here with recommendations on directions of future research endeavors. En ligne : http://dx.doi.org/10.1186/s13229-015-0019-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Sex differences in brain plasticity: a new hypothesis for sex ratio bias in autism / Laurent MOTTRON in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-19 Titre : Sex differences in brain plasticity: a new hypothesis for sex ratio bias in autism Type de document : Texte imprimé et/ou numérique Auteurs : Laurent MOTTRON, Auteur ; Pauline DURET, Auteur ; Sophia MUELLER, Auteur ; Robert D. MOORE, Auteur ; Baudouin FORGEOT D'ARC, Auteur ; Sebastien JACQUEMONT, Auteur ; Lan XIONG, Auteur Article en page(s) : p.1-19 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Several observations support the hypothesis that differences in synaptic and regional cerebral plasticity between the sexes account for the high ratio of males to females in autism. First, males are more susceptible than females to perturbations in genes involved in synaptic plasticity. Second, sex-related differences in non-autistic brain structure and function are observed in highly variable regions, namely, the heteromodal associative cortices, and overlap with structural particularities and enhanced activity of perceptual associative regions in autistic individuals. Finally, functional cortical reallocations following brain lesions in non-autistic adults (for example, traumatic brain injury, multiple sclerosis) are sex-dependent. Interactions between genetic sex and hormones may therefore result in higher synaptic and consecutively regional plasticity in perceptual brain areas in males than in females. The onset of autism may largely involve mutations altering synaptic plasticity that create a plastic reaction affecting the most variable and sexually dimorphic brain regions. The sex ratio bias in autism may arise because males have a lower threshold than females for the development of this plastic reaction following a genetic or environmental event. En ligne : http://dx.doi.org/10.1186/s13229-015-0024-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Sex differences in brain plasticity: a new hypothesis for sex ratio bias in autism [Texte imprimé et/ou numérique] / Laurent MOTTRON, Auteur ; Pauline DURET, Auteur ; Sophia MUELLER, Auteur ; Robert D. MOORE, Auteur ; Baudouin FORGEOT D'ARC, Auteur ; Sebastien JACQUEMONT, Auteur ; Lan XIONG, Auteur . - p.1-19. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-19 Index. décimale : PER Périodiques Résumé : Several observations support the hypothesis that differences in synaptic and regional cerebral plasticity between the sexes account for the high ratio of males to females in autism. First, males are more susceptible than females to perturbations in genes involved in synaptic plasticity. Second, sex-related differences in non-autistic brain structure and function are observed in highly variable regions, namely, the heteromodal associative cortices, and overlap with structural particularities and enhanced activity of perceptual associative regions in autistic individuals. Finally, functional cortical reallocations following brain lesions in non-autistic adults (for example, traumatic brain injury, multiple sclerosis) are sex-dependent. Interactions between genetic sex and hormones may therefore result in higher synaptic and consecutively regional plasticity in perceptual brain areas in males than in females. The onset of autism may largely involve mutations altering synaptic plasticity that create a plastic reaction affecting the most variable and sexually dimorphic brain regions. The sex ratio bias in autism may arise because males have a lower threshold than females for the development of this plastic reaction following a genetic or environmental event. En ligne : http://dx.doi.org/10.1186/s13229-015-0024-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Erratum: A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome / Alexander KOLEVZON in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-1 Titre : Erratum: A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Alexander KOLEVZON, Auteur ; Lauren BUSH, Auteur ; A. Ting WANG, Auteur ; Danielle B. HALPERN, Auteur ; Yitzchak FRANK, Auteur ; David GRODBERG, Auteur ; Robert RAPAPORT, Auteur ; Teresa TAVASSOLI, Auteur ; William CHAPLIN, Auteur ; Latha SOORYA, Auteur ; Joseph D. BUXBAUM, Auteur Article en page(s) : p.1-1 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-015-0025-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Erratum: A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome [Texte imprimé et/ou numérique] / Alexander KOLEVZON, Auteur ; Lauren BUSH, Auteur ; A. Ting WANG, Auteur ; Danielle B. HALPERN, Auteur ; Yitzchak FRANK, Auteur ; David GRODBERG, Auteur ; Robert RAPAPORT, Auteur ; Teresa TAVASSOLI, Auteur ; William CHAPLIN, Auteur ; Latha SOORYA, Auteur ; Joseph D. BUXBAUM, Auteur . - p.1-1. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-1 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-015-0025-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study / Daniel S. MESSINGER in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-12 Titre : Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study Type de document : Texte imprimé et/ou numérique Auteurs : Daniel S. MESSINGER, Auteur ; Gregory S. YOUNG, Auteur ; Sara Jane WEBB, Auteur ; Sally OZONOFF, Auteur ; Susan E. BRYSON, Auteur ; Alice S. CARTER, Auteur ; Leslie J. CARVER, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Suzanne CURTIN, Auteur ; Karen DOBKINS, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Ted HUTMAN, Auteur ; Jana M. IVERSON, Auteur ; Rebecca LANDA, Auteur ; Charles A. NELSON, Auteur ; Wendy L. STONE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Lonnie ZWAIGENBAUM, Auteur Article en page(s) : p.1-12 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The increased male prevalence of autism spectrum disorder (ASD) may be mirrored by the early emergence of sex differences in ASD symptoms and cognitive functioning. The female protective effect hypothesis posits that ASD recurrence and symptoms will be higher among relatives of female probands. This study examined sex differences and sex of proband differences in ASD outcome and in the development of ASD symptoms and cognitive functioning among the high-risk younger siblings of ASD probands and low-risk children. En ligne : http://dx.doi.org/10.1186/s13229-015-0027-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study [Texte imprimé et/ou numérique] / Daniel S. MESSINGER, Auteur ; Gregory S. YOUNG, Auteur ; Sara Jane WEBB, Auteur ; Sally OZONOFF, Auteur ; Susan E. BRYSON, Auteur ; Alice S. CARTER, Auteur ; Leslie J. CARVER, Auteur ; Tony CHARMAN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Suzanne CURTIN, Auteur ; Karen DOBKINS, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Ted HUTMAN, Auteur ; Jana M. IVERSON, Auteur ; Rebecca LANDA, Auteur ; Charles A. NELSON, Auteur ; Wendy L. STONE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Lonnie ZWAIGENBAUM, Auteur . - p.1-12. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-12 Index. décimale : PER Périodiques Résumé : The increased male prevalence of autism spectrum disorder (ASD) may be mirrored by the early emergence of sex differences in ASD symptoms and cognitive functioning. The female protective effect hypothesis posits that ASD recurrence and symptoms will be higher among relatives of female probands. This study examined sex differences and sex of proband differences in ASD outcome and in the development of ASD symptoms and cognitive functioning among the high-risk younger siblings of ASD probands and low-risk children. En ligne : http://dx.doi.org/10.1186/s13229-015-0027-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Sex-different abnormalities in the right second to fourth digit ratio in Japanese individuals with autism spectrum disorders / Yasuhiro MASUYA in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-10 Titre : Sex-different abnormalities in the right second to fourth digit ratio in Japanese individuals with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Yasuhiro MASUYA, Auteur ; Yuko OKAMOTO, Auteur ; Keisuke INOHARA, Auteur ; Yukiko MATSUMURA, Auteur ; Toru FUJIOKA, Auteur ; Yuji WADA, Auteur ; Hirotaka KOSAKA, Auteur Article en page(s) : p.1-10 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The prevalence of autism spectrum disorders (ASDs) is higher in men than in women. The extreme male brain theory proposes that excessive prenatal testosterone activity could be a risk factor for ASDs. However, it is unclear whether prenatal sex hormone activity is a risk factor for women. The ratio of the length of the second to fourth digits (2D:4D) is considered to be a biomarker of the prenatal ratio of testosterone to estrogen. Therefore, this study compared the 2D:4D ratios of women with and without ASDs to determine if prenatal sex hormone activity could be a risk factor for ASDs in women. En ligne : http://dx.doi.org/10.1186/s13229-015-0028-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Sex-different abnormalities in the right second to fourth digit ratio in Japanese individuals with autism spectrum disorders [Texte imprimé et/ou numérique] / Yasuhiro MASUYA, Auteur ; Yuko OKAMOTO, Auteur ; Keisuke INOHARA, Auteur ; Yukiko MATSUMURA, Auteur ; Toru FUJIOKA, Auteur ; Yuji WADA, Auteur ; Hirotaka KOSAKA, Auteur . - p.1-10. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-10 Index. décimale : PER Périodiques Résumé : The prevalence of autism spectrum disorders (ASDs) is higher in men than in women. The extreme male brain theory proposes that excessive prenatal testosterone activity could be a risk factor for ASDs. However, it is unclear whether prenatal sex hormone activity is a risk factor for women. The ratio of the length of the second to fourth digits (2D:4D) is considered to be a biomarker of the prenatal ratio of testosterone to estrogen. Therefore, this study compared the 2D:4D ratios of women with and without ASDs to determine if prenatal sex hormone activity could be a risk factor for ASDs in women. En ligne : http://dx.doi.org/10.1186/s13229-015-0028-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders / Bradley P. ANDER in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-13 Titre : Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Bradley P. ANDER, Auteur ; Nicole BARGER, Auteur ; Boryana STAMOVA, Auteur ; Frank R. SHARP, Auteur ; Cynthia M. SCHUMANN, Auteur Article en page(s) : p.1-13 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) likely involve dysregulation of multiple genes related to brain function and development. Abnormalities in individual regulatory small non-coding RNA (sncRNA), including microRNA (miRNA), could have profound effects upon multiple functional pathways. We assessed whether a brain region associated with core social impairments in ASD, the superior temporal sulcus (STS), would evidence greater transcriptional dysregulation of sncRNA than adjacent, yet functionally distinct, primary auditory cortex (PAC). En ligne : http://dx.doi.org/10.1186/s13229-015-0029-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders [Texte imprimé et/ou numérique] / Bradley P. ANDER, Auteur ; Nicole BARGER, Auteur ; Boryana STAMOVA, Auteur ; Frank R. SHARP, Auteur ; Cynthia M. SCHUMANN, Auteur . - p.1-13. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-13 Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) likely involve dysregulation of multiple genes related to brain function and development. Abnormalities in individual regulatory small non-coding RNA (sncRNA), including microRNA (miRNA), could have profound effects upon multiple functional pathways. We assessed whether a brain region associated with core social impairments in ASD, the superior temporal sulcus (STS), would evidence greater transcriptional dysregulation of sncRNA than adjacent, yet functionally distinct, primary auditory cortex (PAC). En ligne : http://dx.doi.org/10.1186/s13229-015-0029-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Erratum: Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder / Christine W. NORDAHL in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-1 Titre : Erratum: Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Christine W. NORDAHL, Auteur ; Ana-Maria IOSIF, Auteur ; Gregory S. YOUNG, Auteur ; Lee Michael PERRY, Auteur ; Robert DOUGHERTY, Auteur ; Aaron LEE, Auteur ; Deana LI, Auteur ; Michael H. BUONOCORE, Auteur ; Tony SIMON, Auteur ; Sally J ROGERS, Auteur ; Brian WANDELL, Auteur ; David G. AMARAL, Auteur Article en page(s) : p.1-1 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-015-0030-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Erratum: Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder [Texte imprimé et/ou numérique] / Christine W. NORDAHL, Auteur ; Ana-Maria IOSIF, Auteur ; Gregory S. YOUNG, Auteur ; Lee Michael PERRY, Auteur ; Robert DOUGHERTY, Auteur ; Aaron LEE, Auteur ; Deana LI, Auteur ; Michael H. BUONOCORE, Auteur ; Tony SIMON, Auteur ; Sally J ROGERS, Auteur ; Brian WANDELL, Auteur ; David G. AMARAL, Auteur . - p.1-1. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-1 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-015-0030-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Measuring the value of social engagement in adults with and without autism / Indu DUBEY in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-9 Titre : Measuring the value of social engagement in adults with and without autism Type de document : Texte imprimé et/ou numérique Auteurs : Indu DUBEY, Auteur ; Danielle ROPAR, Auteur ; Antonia HAMILTON, Auteur Article en page(s) : p.1-9 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Differences in social communication are commonly reported in autism spectrum condition (ASC). A recent theory attributes this to a reduced motivation to engage with others, that is, deficits in social motivation. However, there are currently few simple, direct, behavioural ways to test this claim. This study uses a new behavioural measure of social motivation to test if preferences for direct gaze and face stimuli are linked to autistic traits or an ASC diagnosis. Our novel choose-a-movie (CAM) paradigm measures the effort participants invest to see particular stimuli. This aspect of social motivation is also known as social seeking. En ligne : http://dx.doi.org/10.1186/s13229-015-0031-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Measuring the value of social engagement in adults with and without autism [Texte imprimé et/ou numérique] / Indu DUBEY, Auteur ; Danielle ROPAR, Auteur ; Antonia HAMILTON, Auteur . - p.1-9. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-9 Index. décimale : PER Périodiques Résumé : Differences in social communication are commonly reported in autism spectrum condition (ASC). A recent theory attributes this to a reduced motivation to engage with others, that is, deficits in social motivation. However, there are currently few simple, direct, behavioural ways to test this claim. This study uses a new behavioural measure of social motivation to test if preferences for direct gaze and face stimuli are linked to autistic traits or an ASC diagnosis. Our novel choose-a-movie (CAM) paradigm measures the effort participants invest to see particular stimuli. This aspect of social motivation is also known as social seeking. En ligne : http://dx.doi.org/10.1186/s13229-015-0031-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

The psychometric properties of the Quantitative-Checklist for Autism in Toddlers (Q-CHAT) as a measure of autistic traits in a community sample of Singaporean infants and toddlers / I. MAGIATI in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-14 Titre : The psychometric properties of the Quantitative-Checklist for Autism in Toddlers (Q-CHAT) as a measure of autistic traits in a community sample of Singaporean infants and toddlers Type de document : Texte imprimé et/ou numérique Auteurs : I. MAGIATI, Auteur ; D. A. GOH, Auteur ; S. J. LIM, Auteur ; D. Z. Q. GAN, Auteur ; J. C. L. LEONG, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur ; A. RIFKIN-GRABOI, Auteur ; Birit F. P. BROEKMAN, Auteur ; Seang Mei SAW, Auteur ; Yap Seng CHONG, Auteur ; K. KWEK, Auteur ; P. D. GLUCKMAN, Auteur ; S. B. LIM, Auteur ; M. J. MEANEY, Auteur Article en page(s) : p.1-14 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : There is growing research evidence that subclinical autistic traits are elevated in relatives of individuals with autism spectrum disorder (ASD), continuously distributed in the general population and likely to share common etiology with ASD. A number of measures have been developed to assess autistic traits quantitatively in unselected samples. So far, the Quantitative-Checklist for Autism in Toddlers (Q-CHAT) is one of very few measures developed for use with toddlers as young as 18 months, but little is known about its measurement properties and factor structure. En ligne : http://dx.doi.org/10.1186/s13229-015-0032-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] The psychometric properties of the Quantitative-Checklist for Autism in Toddlers (Q-CHAT) as a measure of autistic traits in a community sample of Singaporean infants and toddlers [Texte imprimé et/ou numérique] / I. MAGIATI, Auteur ; D. A. GOH, Auteur ; S. J. LIM, Auteur ; D. Z. Q. GAN, Auteur ; J. C. L. LEONG, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur ; A. RIFKIN-GRABOI, Auteur ; Birit F. P. BROEKMAN, Auteur ; Seang Mei SAW, Auteur ; Yap Seng CHONG, Auteur ; K. KWEK, Auteur ; P. D. GLUCKMAN, Auteur ; S. B. LIM, Auteur ; M. J. MEANEY, Auteur . - p.1-14. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-14 Index. décimale : PER Périodiques Résumé : There is growing research evidence that subclinical autistic traits are elevated in relatives of individuals with autism spectrum disorder (ASD), continuously distributed in the general population and likely to share common etiology with ASD. A number of measures have been developed to assess autistic traits quantitatively in unselected samples. So far, the Quantitative-Checklist for Autism in Toddlers (Q-CHAT) is one of very few measures developed for use with toddlers as young as 18 months, but little is known about its measurement properties and factor structure. En ligne : http://dx.doi.org/10.1186/s13229-015-0032-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Erratum to: NTRK2 expression levels are reduced in laser captured pyramidal neurons from the anterior cingulate cortex in males with autism spectrum disorder / Michelle J. CHANDLEY in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-1 Titre : Erratum to: NTRK2 expression levels are reduced in laser captured pyramidal neurons from the anterior cingulate cortex in males with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Michelle J. CHANDLEY, Auteur ; Jessica D. CRAWFORD, Auteur ; Attila SZEBENI, Auteur ; Katalin SZEBENI, Auteur ; Gregory A. ORDWAY, Auteur Article en page(s) : p.1-1 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-015-0033-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Erratum to: NTRK2 expression levels are reduced in laser captured pyramidal neurons from the anterior cingulate cortex in males with autism spectrum disorder [Texte imprimé et/ou numérique] / Michelle J. CHANDLEY, Auteur ; Jessica D. CRAWFORD, Auteur ; Attila SZEBENI, Auteur ; Katalin SZEBENI, Auteur ; Gregory A. ORDWAY, Auteur . - p.1-1. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-1 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-015-0033-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice / Neha UPPAL in Molecular Autism, (June 2015)  

Public ISBD [article]  inMolecular Autism > (June 2015) . - p.1-10 Titre : Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice Type de document : Texte imprimé et/ou numérique Auteurs : Neha UPPAL, Auteur ; Rishi PURI, Auteur ; Frank YUK, Auteur ; William G. M. JANSSEN, Auteur ; Ozlem BOZDAGI-GUNAL, Auteur ; Hala HARONY-NICOLAS, Auteur ; Dara L. DICKSTEIN, Auteur ; Joseph D. BUXBAUM, Auteur ; Patrick R. HOF, Auteur Article en page(s) : p.1-10 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The genetics of autism spectrum disorder (hereafter referred to as “autism”) are rapidly unfolding, with a significant increase in the identification of genes implicated in the disorder. Many of these genes are part of a complex landscape of genetic variants that are thought to act together to cause the behavioral phenotype associated with autism. One of the few single-locus causes of autism involves a mutation in the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene. Previous electrophysiological studies in mice with Shank3 mutations demonstrated impairment in synaptic long-term potentiation, suggesting a potential disruption at the synapse. En ligne : http://dx.doi.org/10.1186/s13229-015-0036-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice [Texte imprimé et/ou numérique] / Neha UPPAL, Auteur ; Rishi PURI, Auteur ; Frank YUK, Auteur ; William G. M. JANSSEN, Auteur ; Ozlem BOZDAGI-GUNAL, Auteur ; Hala HARONY-NICOLAS, Auteur ; Dara L. DICKSTEIN, Auteur ; Joseph D. BUXBAUM, Auteur ; Patrick R. HOF, Auteur . - p.1-10. Langues : Anglais (eng) in Molecular Autism > (June 2015) . - p.1-10 Index. décimale : PER Périodiques Résumé : The genetics of autism spectrum disorder (hereafter referred to as “autism”) are rapidly unfolding, with a significant increase in the identification of genes implicated in the disorder. Many of these genes are part of a complex landscape of genetic variants that are thought to act together to cause the behavioral phenotype associated with autism. One of the few single-locus causes of autism involves a mutation in the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene. Previous electrophysiological studies in mice with Shank3 mutations demonstrated impairment in synaptic long-term potentiation, suggesting a potential disruption at the synapse. En ligne : http://dx.doi.org/10.1186/s13229-015-0036-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277