Corpus callosum area in children and adults with autism / Molly B. D. PRIGGE in Research in Autism Spectrum Disorders, 7-2 (February 2013)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 7-2 (February 2013) . - p.221-234 Titre : Corpus callosum area in children and adults with autism Type de document : Texte imprimé et/ou numérique Auteurs : Molly B. D. PRIGGE, Auteur ; Nicholas LANGE, Auteur ; Erin D. BIGLER, Auteur ; Tricia L. MERKLEY, Auteur ; E. Shannon NEELEY, Auteur ; Tracy J. ABILDSKOV, Auteur ; Alyson L. FROEHLICH, Auteur ; Jared A. NIELSEN, Auteur ; Jason R. COOPERRIDER, Auteur ; Annahir N. CARIELLO, Auteur ; Caitlin RAVICHANDRAN, Auteur ; Andrew A. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur Année de publication : 2013 Article en page(s) : p.221-234 Langues : Anglais (eng) Mots-clés : Autism  Corpus callosum area  Development  MRI Index. décimale : PER Périodiques Résumé : Despite repeated findings of abnormal corpus callosum structure in autism, the developmental trajectories of corpus callosum growth in the disorder have not yet been reported. In this study, we examined corpus callosum size from a developmental perspective across a 30-year age range in a large cross-sectional sample of individuals with autism compared to a typically developing sample. Midsagittal corpus callosum area and the 7 Witelson subregions were examined in 68 males with autism (mean age 14.1 years; range 3'36 years) and 47 males with typical development (mean age 15.3 years; range 4'29 years). Controlling for total brain volume, increased variability in total corpus callosum area was found in autism. In autism, increased midsagittal areas were associated with reduced severity of autism behaviors, higher intelligence, and faster speed of processing (p = 0.003, p = 0.011, p = 0.013, respectively). A trend toward group differences in isthmus development was found (p = 0.029, uncorrected). These results suggest that individuals with autism benefit functionally from increased corpus callosum area. Our cross-sectional examination also shows potential maturational abnormalities in autism, a finding that should be examined further with longitudinal datasets. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.09.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186 [article] Corpus callosum area in children and adults with autism [Texte imprimé et/ou numérique] / Molly B. D. PRIGGE, Auteur ; Nicholas LANGE, Auteur ; Erin D. BIGLER, Auteur ; Tricia L. MERKLEY, Auteur ; E. Shannon NEELEY, Auteur ; Tracy J. ABILDSKOV, Auteur ; Alyson L. FROEHLICH, Auteur ; Jared A. NIELSEN, Auteur ; Jason R. COOPERRIDER, Auteur ; Annahir N. CARIELLO, Auteur ; Caitlin RAVICHANDRAN, Auteur ; Andrew A. ALEXANDER, Auteur ; Janet E. LAINHART, Auteur . - 2013 . - p.221-234. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 7-2 (February 2013) . - p.221-234 Mots-clés : Autism  Corpus callosum area  Development  MRI Index. décimale : PER Périodiques Résumé : Despite repeated findings of abnormal corpus callosum structure in autism, the developmental trajectories of corpus callosum growth in the disorder have not yet been reported. In this study, we examined corpus callosum size from a developmental perspective across a 30-year age range in a large cross-sectional sample of individuals with autism compared to a typically developing sample. Midsagittal corpus callosum area and the 7 Witelson subregions were examined in 68 males with autism (mean age 14.1 years; range 3'36 years) and 47 males with typical development (mean age 15.3 years; range 4'29 years). Controlling for total brain volume, increased variability in total corpus callosum area was found in autism. In autism, increased midsagittal areas were associated with reduced severity of autism behaviors, higher intelligence, and faster speed of processing (p = 0.003, p = 0.011, p = 0.013, respectively). A trend toward group differences in isthmus development was found (p = 0.029, uncorrected). These results suggest that individuals with autism benefit functionally from increased corpus callosum area. Our cross-sectional examination also shows potential maturational abnormalities in autism, a finding that should be examined further with longitudinal datasets. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.09.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186

Longitudinal Heschl's Gyrus Growth During Childhood and Adolescence in Typical Development and Autism / Molly B. D. PRIGGE in Autism Research, 6-2 (April 2013)  

Public ISBD [article]  inAutism Research > 6-2 (April 2013) . - p.78-90 Titre : Longitudinal Heschl's Gyrus Growth During Childhood and Adolescence in Typical Development and Autism Type de document : Texte imprimé et/ou numérique Auteurs : Molly B. D. PRIGGE, Auteur ; Erin D. BIGLER, Auteur ; P. Thomas FLETCHER, Auteur ; Brandon A. ZIELINSKI, Auteur ; Caitlin RAVICHANDRAN, Auteur ; Jeffrey S. ANDERSON, Auteur ; Alyson L. FROEHLICH, Auteur ; Tracy J. ABILDSKOV, Auteur ; Evangelia PAPADOPOLOUS, Auteur ; Kathryn MAASBERG, Auteur ; Jared A. NIELSEN, Auteur ; Andrew A. ALEXANDER, Auteur ; Nicholas LANGE, Auteur ; Janet E. LAINHART, Auteur Année de publication : 2013 Article en page(s) : p.78-90 Langues : Anglais (eng) Mots-clés : autism  Heschl's gyrus  longitudinal development  MRI Index. décimale : PER Périodiques Résumé : Heightened auditory sensitivity and atypical auditory processing are common in autism. Functional studies suggest abnormal neural response and hemispheric activation to auditory stimuli, yet the neurodevelopment underlying atypical auditory function in autism is unknown. In this study, we model longitudinal volumetric growth of Heschl's gyrus gray matter and white matter during childhood and adolescence in 40 individuals with autism and 17 typically developing participants. Up to three time points of magnetic resonance imaging data, collected on average every 2.5 years, were examined from individuals 3–12 years of age at the time of their first scan. Consistent with previous cross-sectional studies, no group differences were found in Heschl's gyrus gray matter volume or asymmetry. However, reduced longitudinal gray matter volumetric growth was found in the right Heschl's gyrus in autism. Reduced longitudinal white matter growth in the left hemisphere was found in the right-handed autism participants. Atypical Heschl's gyrus white matter volumetric growth was found bilaterally in the autism individuals with a history of delayed onset of spoken language. Heightened auditory sensitivity, obtained from the Sensory Profile, was associated with reduced volumetric gray matter growth in the right hemisphere. Our longitudinal analyses revealed dynamic gray and white matter changes in Heschl's gyrus throughout childhood and adolescence in both typical development and autism. En ligne : http://dx.doi.org/10.1002/aur.1265 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=199 [article] Longitudinal Heschl's Gyrus Growth During Childhood and Adolescence in Typical Development and Autism [Texte imprimé et/ou numérique] / Molly B. D. PRIGGE, Auteur ; Erin D. BIGLER, Auteur ; P. Thomas FLETCHER, Auteur ; Brandon A. ZIELINSKI, Auteur ; Caitlin RAVICHANDRAN, Auteur ; Jeffrey S. ANDERSON, Auteur ; Alyson L. FROEHLICH, Auteur ; Tracy J. ABILDSKOV, Auteur ; Evangelia PAPADOPOLOUS, Auteur ; Kathryn MAASBERG, Auteur ; Jared A. NIELSEN, Auteur ; Andrew A. ALEXANDER, Auteur ; Nicholas LANGE, Auteur ; Janet E. LAINHART, Auteur . - 2013 . - p.78-90. Langues : Anglais (eng) in Autism Research > 6-2 (April 2013) . - p.78-90 Mots-clés : autism  Heschl's gyrus  longitudinal development  MRI Index. décimale : PER Périodiques Résumé : Heightened auditory sensitivity and atypical auditory processing are common in autism. Functional studies suggest abnormal neural response and hemispheric activation to auditory stimuli, yet the neurodevelopment underlying atypical auditory function in autism is unknown. In this study, we model longitudinal volumetric growth of Heschl's gyrus gray matter and white matter during childhood and adolescence in 40 individuals with autism and 17 typically developing participants. Up to three time points of magnetic resonance imaging data, collected on average every 2.5 years, were examined from individuals 3–12 years of age at the time of their first scan. Consistent with previous cross-sectional studies, no group differences were found in Heschl's gyrus gray matter volume or asymmetry. However, reduced longitudinal gray matter volumetric growth was found in the right Heschl's gyrus in autism. Reduced longitudinal white matter growth in the left hemisphere was found in the right-handed autism participants. Atypical Heschl's gyrus white matter volumetric growth was found bilaterally in the autism individuals with a history of delayed onset of spoken language. Heightened auditory sensitivity, obtained from the Sensory Profile, was associated with reduced volumetric gray matter growth in the right hemisphere. Our longitudinal analyses revealed dynamic gray and white matter changes in Heschl's gyrus throughout childhood and adolescence in both typical development and autism. En ligne : http://dx.doi.org/10.1002/aur.1265 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=199

Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder / M. B. D. PRIGGE in Journal of Autism and Developmental Disorders, 48-10 (October 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-10 (October 2018) . - p.3319-3329 Titre : Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : M. B. D. PRIGGE, Auteur ; Erin D. BIGLER, Auteur ; B. G. TRAVERS, Auteur ; A. FROEHLICH, Auteur ; Tracy J. ABILDSKOV, Auteur ; Jeffrey S. ANDERSON, Auteur ; A. L. ALEXANDER, Auteur ; N. LANGE, Auteur ; J. E. LAINHART, Auteur ; B. A. ZIELINSKI, Auteur Article en page(s) : p.3319-3329 Langues : Anglais (eng) Mots-clés : Autism severity  Autism spectrum disorder (ASD)  Brain development  Cortical thickness  Longitudinal  Social Responsiveness Scale (SRS) Index. décimale : PER Périodiques Résumé : The relationship between brain development and clinical heterogeneity in autism (ASD) is unknown. This study examines the Social Responsiveness Scale (SRS) in relation to the longitudinal development of cortical thickness. Participants (N = 91 ASD, N = 56 TDC; 3-39 years at first scan) were scanned up to three times over a 7-year period. Mixed-effects models examined cortical thickness in relation to SRS score. ASD participants with higher SRS scores showed regionally increased age-related cortical thinning. Regional thickness differences and reduced age-related cortical thinning were found in predominantly right lateralized regions in ASD with decreasing SRS scores over time. Our findings emphasize the importance of examining clinical phenotypes in brain-based studies of ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3566-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 [article] Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / M. B. D. PRIGGE, Auteur ; Erin D. BIGLER, Auteur ; B. G. TRAVERS, Auteur ; A. FROEHLICH, Auteur ; Tracy J. ABILDSKOV, Auteur ; Jeffrey S. ANDERSON, Auteur ; A. L. ALEXANDER, Auteur ; N. LANGE, Auteur ; J. E. LAINHART, Auteur ; B. A. ZIELINSKI, Auteur . - p.3319-3329. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-10 (October 2018) . - p.3319-3329 Mots-clés : Autism severity  Autism spectrum disorder (ASD)  Brain development  Cortical thickness  Longitudinal  Social Responsiveness Scale (SRS) Index. décimale : PER Périodiques Résumé : The relationship between brain development and clinical heterogeneity in autism (ASD) is unknown. This study examines the Social Responsiveness Scale (SRS) in relation to the longitudinal development of cortical thickness. Participants (N = 91 ASD, N = 56 TDC; 3-39 years at first scan) were scanned up to three times over a 7-year period. Mixed-effects models examined cortical thickness in relation to SRS score. ASD participants with higher SRS scores showed regionally increased age-related cortical thinning. Regional thickness differences and reduced age-related cortical thinning were found in predominantly right lateralized regions in ASD with decreasing SRS scores over time. Our findings emphasize the importance of examining clinical phenotypes in brain-based studies of ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3566-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369

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