Dépouillements

The effect of contingent imitation intervention on children with autism spectrum disorder and co-occurring intellectual disabilities / Yuka ISHIZUKA in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101783 Titre : The effect of contingent imitation intervention on children with autism spectrum disorder and co-occurring intellectual disabilities Type de document : Texte imprimé et/ou numérique Auteurs : Yuka ISHIZUKA, Auteur ; Junichi YAMAMOTO, Auteur Article en page(s) : 101783 Langues : Anglais (eng) Mots-clés : Imitation  Contingent imitation  Reciprocal imitation training  Prompting  Children with autism spectrum disorder and co-occurring intellectual disabilities Index. décimale : PER Périodiques Résumé : Background Imitation plays a crucial role in the development of social communication, and it is a skill that is often missing in children with autism spectrum disorder and co-occurring intellectual disabilities. Contingent imitation (CI) results in increased social eye gaze, an imitation cue for children with ASD. A series of studies on Reciprocal Imitation Training (RIT) intervention that included CI has demonstrated an increase in imitation frequency. However, little is known about CI intervention’s effects on motor, object, and vocal imitation accuracy in children with ASD-ID. Method The participants in this study were six 4-year-old children with ASD-ID. A single case experimental design with multiple probes across target behaviors was used to identify CI intervention's efficacy on the motor, object, and vocal imitation. Moreover, pre-and post-assessment analysis evaluated socially engaged imitation and imitation turn-taking. Results Most motor, object, and vocal imitation accuracy increased through the CI intervention. However, individual adaptations such as prompting for looking behaviors and motor responses were required to increase specific target behaviors. Moreover, all children increased socially engaged imitation and imitation turn-taking through CI intervention and CI + prompting intervention. Conclusions En ligne : https://doi.org/10.1016/j.rasd.2021.101783 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] The effect of contingent imitation intervention on children with autism spectrum disorder and co-occurring intellectual disabilities [Texte imprimé et/ou numérique] / Yuka ISHIZUKA, Auteur ; Junichi YAMAMOTO, Auteur . - 101783. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101783 Mots-clés : Imitation  Contingent imitation  Reciprocal imitation training  Prompting  Children with autism spectrum disorder and co-occurring intellectual disabilities Index. décimale : PER Périodiques Résumé : Background Imitation plays a crucial role in the development of social communication, and it is a skill that is often missing in children with autism spectrum disorder and co-occurring intellectual disabilities. Contingent imitation (CI) results in increased social eye gaze, an imitation cue for children with ASD. A series of studies on Reciprocal Imitation Training (RIT) intervention that included CI has demonstrated an increase in imitation frequency. However, little is known about CI intervention’s effects on motor, object, and vocal imitation accuracy in children with ASD-ID. Method The participants in this study were six 4-year-old children with ASD-ID. A single case experimental design with multiple probes across target behaviors was used to identify CI intervention's efficacy on the motor, object, and vocal imitation. Moreover, pre-and post-assessment analysis evaluated socially engaged imitation and imitation turn-taking. Results Most motor, object, and vocal imitation accuracy increased through the CI intervention. However, individual adaptations such as prompting for looking behaviors and motor responses were required to increase specific target behaviors. Moreover, all children increased socially engaged imitation and imitation turn-taking through CI intervention and CI + prompting intervention. Conclusions En ligne : https://doi.org/10.1016/j.rasd.2021.101783 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review / Matthijs MOERKERKE in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101785 Titre : Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Matthijs MOERKERKE, Auteur ; Marie-Laure BONTE, Auteur ; Nicky DANIELS, Auteur ; Viktoria CHUBAR, Auteur ; Kaat ALAERTS, Auteur ; Jean STEYAERT, Auteur ; Bart BOETS, Auteur Article en page(s) : 101785 Langues : Anglais (eng) Mots-clés : Oxytocin receptor gene  Epigenetics  DNA methylation  Autism  Social behaviour Index. décimale : PER Périodiques Résumé : There is emerging evidence implicating oxytocin receptor gene (OXTR) DNA methylation (DNAm) in social behaviour. This review investigated its association with autism spectrum disorder (ASD) characteristics and related social dimensions, both in individuals with and without ASD. Twelve articles investigating OXTR DNAm in relation to ASD, social perception/cognition and social anxiety were included. We found that hypermethylation is associated with (i) higher quantitative autism traits in adults, reflecting a higher incidence of autism characteristics, (ii) increased brain activity while performing social tasks (indicating a higher need for resources) and (iii) decreased functional connectivity. (iv) Contradictory, hypomethylation was found to be present in children (especially boys) with ASD and was also associated with more social anxiety. While the included studies displayed a large variability, for example in terms of population characteristics, analysed OXTR DNAm regions, and adopted scales/questionnaires, an initial developmental pattern of results emerged, suggesting an association between hypermethylation of OXTR and autism traits in adults. Nonetheless, future studies are warranted to corroborate these initial conclusions. En ligne : https://doi.org/10.1016/j.rasd.2021.101785 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review [Texte imprimé et/ou numérique] / Matthijs MOERKERKE, Auteur ; Marie-Laure BONTE, Auteur ; Nicky DANIELS, Auteur ; Viktoria CHUBAR, Auteur ; Kaat ALAERTS, Auteur ; Jean STEYAERT, Auteur ; Bart BOETS, Auteur . - 101785. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101785 Mots-clés : Oxytocin receptor gene  Epigenetics  DNA methylation  Autism  Social behaviour Index. décimale : PER Périodiques Résumé : There is emerging evidence implicating oxytocin receptor gene (OXTR) DNA methylation (DNAm) in social behaviour. This review investigated its association with autism spectrum disorder (ASD) characteristics and related social dimensions, both in individuals with and without ASD. Twelve articles investigating OXTR DNAm in relation to ASD, social perception/cognition and social anxiety were included. We found that hypermethylation is associated with (i) higher quantitative autism traits in adults, reflecting a higher incidence of autism characteristics, (ii) increased brain activity while performing social tasks (indicating a higher need for resources) and (iii) decreased functional connectivity. (iv) Contradictory, hypomethylation was found to be present in children (especially boys) with ASD and was also associated with more social anxiety. While the included studies displayed a large variability, for example in terms of population characteristics, analysed OXTR DNAm regions, and adopted scales/questionnaires, an initial developmental pattern of results emerged, suggesting an association between hypermethylation of OXTR and autism traits in adults. Nonetheless, future studies are warranted to corroborate these initial conclusions. En ligne : https://doi.org/10.1016/j.rasd.2021.101785 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Longitudinal stability of salivary microRNA biomarkers in children and adolescents with autism spectrum disorder / David LEVITSKIY in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101788 Titre : Longitudinal stability of salivary microRNA biomarkers in children and adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : David LEVITSKIY, Auteur ; Alexandra CONFAIR, Auteur ; Kayla E. WAGNER, Auteur ; Samantha DEVITA, Auteur ; Nicole SHEA, Auteur ; Elizabeth P. MCKERNAN, Auteur ; Justin KOPEC, Auteur ; Natalie RUSSO, Auteur ; Frank A. MIDDLETON, Auteur ; Steven D. HICKS, Auteur Article en page(s) : 101788 Langues : Anglais (eng) Mots-clés : Prognosis  Biomarkers  Saliva  RNA  microRNA  Autism Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a complex neurological condition with increasing prevalence. Few tools accurately predict the developmental trajectory of children with ASD. Such tools would allow clinicians to provide accurate prognoses and track the efficacy of therapeutic interventions. Salivary RNAs that reflect the genetic-environmental interactions underlying ASD may provide objective measures of symptom severity and developmental outcomes. This study investigated whether salivary RNAs previously identified in childhood ASD remain perturbed in older children. We also explored whether RNA candidates changed with therapeutic intervention. Method A case-control design was used to characterize levels of 78 saliva RNA candidates among 96 children (48 ASD, 48 non-ASD, mean age: 11 years). Thirty-one children (22 ASD, 9 non-ASD developmental delay, mean age: 4 years) were followed longitudinally to explore changes of RNA candidates during early intervention. Saliva RNA and standardized behavioral assessments were collected for each participant. Associations between candidate RNAs and behavioral scores were determined in both groups via Spearman Correlation. Changes in candidate RNAs across two time-points were assessed in the younger cohort via Wilcoxon rank-sum test. Results Seven RNAs were associated with VABS-II and BASC scores in the older group ([R] >0.25, FDR? En ligne : https://doi.org/10.1016/j.rasd.2021.101788 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Longitudinal stability of salivary microRNA biomarkers in children and adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / David LEVITSKIY, Auteur ; Alexandra CONFAIR, Auteur ; Kayla E. WAGNER, Auteur ; Samantha DEVITA, Auteur ; Nicole SHEA, Auteur ; Elizabeth P. MCKERNAN, Auteur ; Justin KOPEC, Auteur ; Natalie RUSSO, Auteur ; Frank A. MIDDLETON, Auteur ; Steven D. HICKS, Auteur . - 101788. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101788 Mots-clés : Prognosis  Biomarkers  Saliva  RNA  microRNA  Autism Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a complex neurological condition with increasing prevalence. Few tools accurately predict the developmental trajectory of children with ASD. Such tools would allow clinicians to provide accurate prognoses and track the efficacy of therapeutic interventions. Salivary RNAs that reflect the genetic-environmental interactions underlying ASD may provide objective measures of symptom severity and developmental outcomes. This study investigated whether salivary RNAs previously identified in childhood ASD remain perturbed in older children. We also explored whether RNA candidates changed with therapeutic intervention. Method A case-control design was used to characterize levels of 78 saliva RNA candidates among 96 children (48 ASD, 48 non-ASD, mean age: 11 years). Thirty-one children (22 ASD, 9 non-ASD developmental delay, mean age: 4 years) were followed longitudinally to explore changes of RNA candidates during early intervention. Saliva RNA and standardized behavioral assessments were collected for each participant. Associations between candidate RNAs and behavioral scores were determined in both groups via Spearman Correlation. Changes in candidate RNAs across two time-points were assessed in the younger cohort via Wilcoxon rank-sum test. Results Seven RNAs were associated with VABS-II and BASC scores in the older group ([R] >0.25, FDR? En ligne : https://doi.org/10.1016/j.rasd.2021.101788 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Association between early androgens and autistic traits: A systematic review and meta-analysis / Nadia COSCINI in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101789 Titre : Association between early androgens and autistic traits: A systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Nadia COSCINI, Auteur ; Katrina WILLIAMS, Auteur ; Denise CHEW, Auteur ; Kenneth C. PANG, Auteur ; Michele A. O’CONNELL, Auteur ; Tamara MAY, Auteur Article en page(s) : 101789 Langues : Anglais (eng) Mots-clés : Autism  Androgen  Testosterone  Extreme male brain  Systematic review Index. décimale : PER Périodiques Résumé : Background We systematically reviewed evidence for the androgen theory which proposes exposure to elevated levels of androgens in early development predisposes to autistic behaviour. Method MEDLINE, EMBASE and Pubmed were searched for studies measuring androgens in mother or child during pregnancy or the first year of life and examined autistic behaviours (including social ability and repetitive behaviour) and language measured up to age 24 years. Results Twenty-five of 3,041 publications met inclusion criteria, exploring 11 unique cohorts. Overall quality of evidence was very low as studies were non-experimental and most had high risk of bias. Only one research group found significant associations between autistic behaviour and androgens in amniotic fluid. There were mixed findings across the studies reviewed. Meta-analysis indicated a small significant pooled association between autistic behaviour and androgens in amniotic fluid (males and females combined; 3 studies), 0.28 [95 % CI 0.14, 0.41], also significant in males and females separately. Conclusions Despite interest in this topic, of studies exploring direct measures of early androgens and later autistic traits, there is only a small amount of low-quality evidence from independent cohorts. The androgen theory of autism is neither confirmed nor refuted by the existing association studies included in this review. En ligne : https://doi.org/10.1016/j.rasd.2021.101789 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Association between early androgens and autistic traits: A systematic review and meta-analysis [Texte imprimé et/ou numérique] / Nadia COSCINI, Auteur ; Katrina WILLIAMS, Auteur ; Denise CHEW, Auteur ; Kenneth C. PANG, Auteur ; Michele A. O’CONNELL, Auteur ; Tamara MAY, Auteur . - 101789. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101789 Mots-clés : Autism  Androgen  Testosterone  Extreme male brain  Systematic review Index. décimale : PER Périodiques Résumé : Background We systematically reviewed evidence for the androgen theory which proposes exposure to elevated levels of androgens in early development predisposes to autistic behaviour. Method MEDLINE, EMBASE and Pubmed were searched for studies measuring androgens in mother or child during pregnancy or the first year of life and examined autistic behaviours (including social ability and repetitive behaviour) and language measured up to age 24 years. Results Twenty-five of 3,041 publications met inclusion criteria, exploring 11 unique cohorts. Overall quality of evidence was very low as studies were non-experimental and most had high risk of bias. Only one research group found significant associations between autistic behaviour and androgens in amniotic fluid. There were mixed findings across the studies reviewed. Meta-analysis indicated a small significant pooled association between autistic behaviour and androgens in amniotic fluid (males and females combined; 3 studies), 0.28 [95 % CI 0.14, 0.41], also significant in males and females separately. Conclusions Despite interest in this topic, of studies exploring direct measures of early androgens and later autistic traits, there is only a small amount of low-quality evidence from independent cohorts. The androgen theory of autism is neither confirmed nor refuted by the existing association studies included in this review. En ligne : https://doi.org/10.1016/j.rasd.2021.101789 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Development of a cell-based metabolic test for the identification of individuals with autism spectrum disorder / Rini PAULY in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101790 Titre : Development of a cell-based metabolic test for the identification of individuals with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Rini PAULY, Auteur ; Lauren CASCIO, Auteur ; Sujata SRIKANTH, Auteur ; Kelly JONES, Auteur ; Skylar SORROW, Auteur ; Rossana CUBILLAN, Auteur ; Chin-Fu CHEN, Auteur ; Cindy SKINNER, Auteur ; Kevin CHAMPAIGNE, Auteur ; Roger E. STEVENSON, Auteur ; Charles E. SCHWARTZ, Auteur ; Luigi BOCCUTO, Auteur Article en page(s) : 101790 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder (ASD)  Tryptophan  Metabolism  Diagnostic test  Screening test Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a common neurodevelopmental condition with a tremendous impact on society and families. The biological basis of ASD has yet to be completely understood and there are no laboratory tests for this condition. Phenotype Mammalian Microarrays (PM-Ms) can distinguish patients with ASD from typically developing (TD) individuals by differential utilization of the amino acid tryptophan. By assessing several parameters of the assay utilizing customized tryptophan-containing PM-M plates, we improved the discrimination of the test, optimized test parameters, and minimized background noise by normalization while controlling for false discoveries. This improved platform can provide the first cell-based metabolic test to validate the clinical diagnosis of ASD and possibly identify individuals at risk even before the occurrence of neuro-behavioral symptoms. En ligne : https://doi.org/10.1016/j.rasd.2021.101790 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Development of a cell-based metabolic test for the identification of individuals with autism spectrum disorder [Texte imprimé et/ou numérique] / Rini PAULY, Auteur ; Lauren CASCIO, Auteur ; Sujata SRIKANTH, Auteur ; Kelly JONES, Auteur ; Skylar SORROW, Auteur ; Rossana CUBILLAN, Auteur ; Chin-Fu CHEN, Auteur ; Cindy SKINNER, Auteur ; Kevin CHAMPAIGNE, Auteur ; Roger E. STEVENSON, Auteur ; Charles E. SCHWARTZ, Auteur ; Luigi BOCCUTO, Auteur . - 101790. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101790 Mots-clés : Autism spectrum disorder (ASD)  Tryptophan  Metabolism  Diagnostic test  Screening test Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a common neurodevelopmental condition with a tremendous impact on society and families. The biological basis of ASD has yet to be completely understood and there are no laboratory tests for this condition. Phenotype Mammalian Microarrays (PM-Ms) can distinguish patients with ASD from typically developing (TD) individuals by differential utilization of the amino acid tryptophan. By assessing several parameters of the assay utilizing customized tryptophan-containing PM-M plates, we improved the discrimination of the test, optimized test parameters, and minimized background noise by normalization while controlling for false discoveries. This improved platform can provide the first cell-based metabolic test to validate the clinical diagnosis of ASD and possibly identify individuals at risk even before the occurrence of neuro-behavioral symptoms. En ligne : https://doi.org/10.1016/j.rasd.2021.101790 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Exploring differences and disparities in school-based services received by students with autism: A systematic review / Jessica SUHRHEINRICH in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101791 Titre : Exploring differences and disparities in school-based services received by students with autism: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Jessica SUHRHEINRICH, Auteur ; Brittney V. ROOT, Auteur ; Melina MELGAREJO, Auteur ; Kelsey S. DICKSON, Auteur ; Sarah VEJNOSKA, Auteur ; Sarah R. REITH, Auteur Article en page(s) : 101791 Langues : Anglais (eng) Mots-clés : Educational services  Service disparities Index. décimale : PER Périodiques Résumé : Background While disparities in general Autism Spectrum Disorder (ASD) diagnoses and services for the population broadly are often documented, the presence and determinants of differences in the services that students with ASD receive specifically in (or funded by) schools are less studied and understood. Method This systematic review sought to characterize the range of services received by students with ASD in school settings; identify individual, family, and program factors associated with receipt of specific services; and identify relationships between services and individual, family or program factors to reveal potential systematic differences and disparities. Article identification involved Keyword searches in ERIC and PsycINFO, abstract. and full text review. Data extraction included basic publication details, school-based services, factors measured across the services examined, type of analysis, service-related results, and study demographics. Results In total, 487 articles were screened and reviewed, resulting in 36 eligible articles. Only one study (3 %) used mixed methodology, while all others used quantitative methodology (97 %, n = 35). Youth clinical characteristics by service type was the most frequently examined factor by service characteristic (58 %, n = 21), followed by youth demographics with service type (36 %, n = 13), family demographics by service type (33 %, n = 12), and youth clinical characteristics by service attributes (33 %, n = 12). The majority of reviewed studies explored differences by student race/ethnicity. Conclusions This systematic review identifies determinants of disparities for school-based services for ASD. Findings from this review serve as a first step in developing targeted implementation efforts to reduce disparities in school-based ASD services. En ligne : https://doi.org/10.1016/j.rasd.2021.101791 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Exploring differences and disparities in school-based services received by students with autism: A systematic review [Texte imprimé et/ou numérique] / Jessica SUHRHEINRICH, Auteur ; Brittney V. ROOT, Auteur ; Melina MELGAREJO, Auteur ; Kelsey S. DICKSON, Auteur ; Sarah VEJNOSKA, Auteur ; Sarah R. REITH, Auteur . - 101791. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101791 Mots-clés : Educational services  Service disparities Index. décimale : PER Périodiques Résumé : Background While disparities in general Autism Spectrum Disorder (ASD) diagnoses and services for the population broadly are often documented, the presence and determinants of differences in the services that students with ASD receive specifically in (or funded by) schools are less studied and understood. Method This systematic review sought to characterize the range of services received by students with ASD in school settings; identify individual, family, and program factors associated with receipt of specific services; and identify relationships between services and individual, family or program factors to reveal potential systematic differences and disparities. Article identification involved Keyword searches in ERIC and PsycINFO, abstract. and full text review. Data extraction included basic publication details, school-based services, factors measured across the services examined, type of analysis, service-related results, and study demographics. Results In total, 487 articles were screened and reviewed, resulting in 36 eligible articles. Only one study (3 %) used mixed methodology, while all others used quantitative methodology (97 %, n = 35). Youth clinical characteristics by service type was the most frequently examined factor by service characteristic (58 %, n = 21), followed by youth demographics with service type (36 %, n = 13), family demographics by service type (33 %, n = 12), and youth clinical characteristics by service attributes (33 %, n = 12). The majority of reviewed studies explored differences by student race/ethnicity. Conclusions This systematic review identifies determinants of disparities for school-based services for ASD. Findings from this review serve as a first step in developing targeted implementation efforts to reduce disparities in school-based ASD services. En ligne : https://doi.org/10.1016/j.rasd.2021.101791 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Get it right, make it easy, see it all: Viewpoints of autistic individuals and parents of autistic individuals about the autism diagnostic process in Australia / Emily D’ARCY in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101792 Titre : Get it right, make it easy, see it all: Viewpoints of autistic individuals and parents of autistic individuals about the autism diagnostic process in Australia Type de document : Texte imprimé et/ou numérique Auteurs : Emily D’ARCY, Auteur ; Sonya GIRDLER, Auteur ; Marita FALKMER, Auteur ; Torbjörn FALKMER, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; John WRAY, Auteur ; Valsamma EAPEN, Auteur ; Kiah EVANS, Auteur Article en page(s) : 101792 Langues : Anglais (eng) Mots-clés : ASD  Diagnosis  Consumer perspective  Assessment Index. décimale : PER Périodiques Résumé : Background The clinical process for being evaluated for an autism diagnosis is often time consuming and stressful for individuals and their caregivers. While experience of and satisfaction with the diagnostic process has been reviewed in the literature, few studies have directly investigated the viewpoints of individuals diagnosed with autism and caregivers of autistic individuals about what is important in the autism diagnostic process. Method A Q methodological design was employed to capture the subjective viewpoints about the diagnostic process of individuals on the autism spectrum and caregivers of autistic individuals. Thirty-eight participants responded to a set of 66 statements representing different aspects of the autism diagnostic process. Results The analysis identified three significant viewpoints: Get it Right, Make it Easy, and See it All. Participants reflected upon the importance of a comprehensive diagnostic assessment process, ease of diagnostic processes, and a holistic approach to autism diagnosis for autistic individuals and caregivers of autistic individuals. Conclusions The findings provide a consumer perspective that encourages reform of the current process for diagnosing autism in Australia, and an insight into what consumers are wanting from diagnostic services. This information is useful for policy-makers and service providers to create a more supportive and client-centred diagnostic process at all levels of service delivery. En ligne : https://doi.org/10.1016/j.rasd.2021.101792 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Get it right, make it easy, see it all: Viewpoints of autistic individuals and parents of autistic individuals about the autism diagnostic process in Australia [Texte imprimé et/ou numérique] / Emily D’ARCY, Auteur ; Sonya GIRDLER, Auteur ; Marita FALKMER, Auteur ; Torbjörn FALKMER, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; John WRAY, Auteur ; Valsamma EAPEN, Auteur ; Kiah EVANS, Auteur . - 101792. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101792 Mots-clés : ASD  Diagnosis  Consumer perspective  Assessment Index. décimale : PER Périodiques Résumé : Background The clinical process for being evaluated for an autism diagnosis is often time consuming and stressful for individuals and their caregivers. While experience of and satisfaction with the diagnostic process has been reviewed in the literature, few studies have directly investigated the viewpoints of individuals diagnosed with autism and caregivers of autistic individuals about what is important in the autism diagnostic process. Method A Q methodological design was employed to capture the subjective viewpoints about the diagnostic process of individuals on the autism spectrum and caregivers of autistic individuals. Thirty-eight participants responded to a set of 66 statements representing different aspects of the autism diagnostic process. Results The analysis identified three significant viewpoints: Get it Right, Make it Easy, and See it All. Participants reflected upon the importance of a comprehensive diagnostic assessment process, ease of diagnostic processes, and a holistic approach to autism diagnosis for autistic individuals and caregivers of autistic individuals. Conclusions The findings provide a consumer perspective that encourages reform of the current process for diagnosing autism in Australia, and an insight into what consumers are wanting from diagnostic services. This information is useful for policy-makers and service providers to create a more supportive and client-centred diagnostic process at all levels of service delivery. En ligne : https://doi.org/10.1016/j.rasd.2021.101792 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Vulnerabilities associated with physical health conditions for emergency department utilization in adolescents with autism spectrum disorder / Guodong LIU in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101800 Titre : Vulnerabilities associated with physical health conditions for emergency department utilization in adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Guodong LIU, Auteur ; Amanda M. PEARL, Auteur ; Lan KONG, Auteur ; Sierra L. BROWN, Auteur ; Djibril M. BA, Auteur ; Doug L. LESLIE, Auteur ; Michael J. MURRAY, Auteur Article en page(s) : 101800 Langues : Anglais (eng) Mots-clés : Autism  Adolescence  Risk factors  Emergency department  Physical and mental health  Service utilization Index. décimale : PER Périodiques Résumé : Background Adolescents with Autism Spectrum Disorder (ASD) have been found to have higher emergency department (ED) utilization due to psychiatric crisis compared to adolescents without ASD. However, little attention has been given to identification of physical health risk factors specifically associated with ED utilization in this population. Method This was a retrospective longitudinal study using the 2005–2014 MarketScan® claims database. We extracted a cohort of subjects with ASD, aged 12–21 and having a minimum of two full consecutive calendar years of enrollment. The outcome variable was a binary indictor of ED utilization during a calendar year. In addition to the univariate association analysis, we performed a multivariable logistic regression analysis to evaluate the independent effects of prior physical health conditions while adjusting for mental health conditions and other potential confounders. Results Our study included 181,686 person-years of data from 63,886 subjects with ASD. The multivariable regression analysis showed that prior physical health conditions were associated with elevated risk for ED visit. In particular, prior injuries posted the highest risk of ED utilization (adjusted odds ratio [aOR]: 2.54; 95 % confidence interval [CI]: 2.35–2.75). Epilepsy and gastrointestinal (GI) problems were also found to be strongly associated with the increased ED utilization (epilepsy: 2.34; 2.10–2.60; GI problems: 2.16; 1.97–2.37). Conclusions This study indicated that individuals with co-occurring physical health conditions appear to be at a high risk for ED visit in adolescents with ASD. These identified risk factors may serve as effective intervention points to refine current standards of care for this historically under-served population. En ligne : https://doi.org/10.1016/j.rasd.2021.101800 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Vulnerabilities associated with physical health conditions for emergency department utilization in adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / Guodong LIU, Auteur ; Amanda M. PEARL, Auteur ; Lan KONG, Auteur ; Sierra L. BROWN, Auteur ; Djibril M. BA, Auteur ; Doug L. LESLIE, Auteur ; Michael J. MURRAY, Auteur . - 101800. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101800 Mots-clés : Autism  Adolescence  Risk factors  Emergency department  Physical and mental health  Service utilization Index. décimale : PER Périodiques Résumé : Background Adolescents with Autism Spectrum Disorder (ASD) have been found to have higher emergency department (ED) utilization due to psychiatric crisis compared to adolescents without ASD. However, little attention has been given to identification of physical health risk factors specifically associated with ED utilization in this population. Method This was a retrospective longitudinal study using the 2005–2014 MarketScan® claims database. We extracted a cohort of subjects with ASD, aged 12–21 and having a minimum of two full consecutive calendar years of enrollment. The outcome variable was a binary indictor of ED utilization during a calendar year. In addition to the univariate association analysis, we performed a multivariable logistic regression analysis to evaluate the independent effects of prior physical health conditions while adjusting for mental health conditions and other potential confounders. Results Our study included 181,686 person-years of data from 63,886 subjects with ASD. The multivariable regression analysis showed that prior physical health conditions were associated with elevated risk for ED visit. In particular, prior injuries posted the highest risk of ED utilization (adjusted odds ratio [aOR]: 2.54; 95 % confidence interval [CI]: 2.35–2.75). Epilepsy and gastrointestinal (GI) problems were also found to be strongly associated with the increased ED utilization (epilepsy: 2.34; 2.10–2.60; GI problems: 2.16; 1.97–2.37). Conclusions This study indicated that individuals with co-occurring physical health conditions appear to be at a high risk for ED visit in adolescents with ASD. These identified risk factors may serve as effective intervention points to refine current standards of care for this historically under-served population. En ligne : https://doi.org/10.1016/j.rasd.2021.101800 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Investigating health-related knowledge and independence for physical and mental health conditions in young adults with autism spectrum disorder / Nancy C. CHEAK-ZAMORA in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101801 Titre : Investigating health-related knowledge and independence for physical and mental health conditions in young adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Nancy C. CHEAK-ZAMORA, Auteur ; Kerri P. NOWELL, Auteur ; Emily HELTERBRAND, Auteur ; Andrew TAIT, Auteur Article en page(s) : 101801 Langues : Anglais (eng) Mots-clés : Young adults  Autism  Physical health  Mental health  Transition  Independence Index. décimale : PER Périodiques Résumé : Background Young adults with autism spectrum disorder’s (YA-ASD) ability to manage their healthcare needs is imperative as they transition to adult care. Method This study evaluated YA-ASD’s knowledge and care-seeking behavior for Physical and Mental Health (PH/MH) conditions. Caregivers (n?=?501), of YA-ASD 16–25 years completed surveys. This study examined the extent to which YA-ASD could describe and seek care for their physical and mental health conditions (i.e. describing and care-seeking behaviors). Multivariate analyses further evaluated YA-ASD’s ability to and predictors of describing and care-seeking behaviors. Results En ligne : https://doi.org/10.1016/j.rasd.2021.101801 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Investigating health-related knowledge and independence for physical and mental health conditions in young adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Nancy C. CHEAK-ZAMORA, Auteur ; Kerri P. NOWELL, Auteur ; Emily HELTERBRAND, Auteur ; Andrew TAIT, Auteur . - 101801. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101801 Mots-clés : Young adults  Autism  Physical health  Mental health  Transition  Independence Index. décimale : PER Périodiques Résumé : Background Young adults with autism spectrum disorder’s (YA-ASD) ability to manage their healthcare needs is imperative as they transition to adult care. Method This study evaluated YA-ASD’s knowledge and care-seeking behavior for Physical and Mental Health (PH/MH) conditions. Caregivers (n?=?501), of YA-ASD 16–25 years completed surveys. This study examined the extent to which YA-ASD could describe and seek care for their physical and mental health conditions (i.e. describing and care-seeking behaviors). Multivariate analyses further evaluated YA-ASD’s ability to and predictors of describing and care-seeking behaviors. Results En ligne : https://doi.org/10.1016/j.rasd.2021.101801 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

Relations among co-occurring psychopathology in youth with autism spectrum disorder, family resilience, and caregiver coping / Michelle MENEZES in Research in Autism Spectrum Disorders, 85 (July 2021)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 85 (July 2021) . - 101803 Titre : Relations among co-occurring psychopathology in youth with autism spectrum disorder, family resilience, and caregiver coping Type de document : Texte imprimé et/ou numérique Auteurs : Michelle MENEZES, Auteur ; Melissa F. ROBINSON, Auteur ; Sydney C. SIMMONS, Auteur ; Kathryn R. SMITH, Auteur ; Nicole ZHONG, Auteur ; Micah O. MAZUREK, Auteur Article en page(s) : 101803 Langues : Anglais (eng) Mots-clés : Autism  ASD  Caregiver  Family  Comorbid  Psychopathology  Resilience  Coping Index. décimale : PER Périodiques Résumé : Background Co-occurring mental health problems are common in youth with autism spectrum disorder (ASD) and are associated with greater caregiver stress; however, it is not known whether such challenges overwhelm caregivers’ ability to cope. Research has demonstrated that families of children with ASD are able to demonstrate resilience; yet, whether family resilience functions as a compensatory or protective factor in ASD families has not been investigated. This study aimed to examine the relations among family resilience, co-occurring psychopathology in youth with ASD, and caregiver coping. Method Data from this study were obtained from the 2016–2018 National Survey of Children’s Health (NSCH). Multiple binary logistic regression was run to examine the associations among commonly co-occurring psychiatric disorders in youth with ASD (i.e., anxiety, depression, attention-deficit/hyperactivity disorder, and behavioral/conduct problems) and caregiver coping. Another multiple binary logistic regression was run to examine whether family resilience moderates the aforementioned relationships. Results Youth with ASD and co-occurring conduct problems or depression were significantly more likely to be cared for by adults who were not coping well. High family resilience was directly associated with lower odds of poor parental coping; nonetheless, co-occurring conduct problems and depression were still associated with worse coping of caregivers after accounting for family resilience. Conclusions Findings indicate that co-occurring depression and conduct problems in ASD youth may overwhelm their caregivers’ coping resources. Results also suggest that interventions targeting family resilience may improve the coping of adults caring for children and adolescents with ASD. En ligne : https://doi.org/10.1016/j.rasd.2021.101803 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Relations among co-occurring psychopathology in youth with autism spectrum disorder, family resilience, and caregiver coping [Texte imprimé et/ou numérique] / Michelle MENEZES, Auteur ; Melissa F. ROBINSON, Auteur ; Sydney C. SIMMONS, Auteur ; Kathryn R. SMITH, Auteur ; Nicole ZHONG, Auteur ; Micah O. MAZUREK, Auteur . - 101803. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 85 (July 2021) . - 101803 Mots-clés : Autism  ASD  Caregiver  Family  Comorbid  Psychopathology  Resilience  Coping Index. décimale : PER Périodiques Résumé : Background Co-occurring mental health problems are common in youth with autism spectrum disorder (ASD) and are associated with greater caregiver stress; however, it is not known whether such challenges overwhelm caregivers’ ability to cope. Research has demonstrated that families of children with ASD are able to demonstrate resilience; yet, whether family resilience functions as a compensatory or protective factor in ASD families has not been investigated. This study aimed to examine the relations among family resilience, co-occurring psychopathology in youth with ASD, and caregiver coping. Method Data from this study were obtained from the 2016–2018 National Survey of Children’s Health (NSCH). Multiple binary logistic regression was run to examine the associations among commonly co-occurring psychiatric disorders in youth with ASD (i.e., anxiety, depression, attention-deficit/hyperactivity disorder, and behavioral/conduct problems) and caregiver coping. Another multiple binary logistic regression was run to examine whether family resilience moderates the aforementioned relationships. Results Youth with ASD and co-occurring conduct problems or depression were significantly more likely to be cared for by adults who were not coping well. High family resilience was directly associated with lower odds of poor parental coping; nonetheless, co-occurring conduct problems and depression were still associated with worse coping of caregivers after accounting for family resilience. Conclusions Findings indicate that co-occurring depression and conduct problems in ASD youth may overwhelm their caregivers’ coping resources. Results also suggest that interventions targeting family resilience may improve the coping of adults caring for children and adolescents with ASD. En ligne : https://doi.org/10.1016/j.rasd.2021.101803 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458