Empirically Based Phenotypic Profiles of Children with Pervasive Developmental Disorders: Interpretation in the Light of the DSM-5 / Kirstin GREAVES-LORD in Journal of Autism and Developmental Disorders, 43-8 (August 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-8 (August 2013) . - p.1784-1797 Titre : Empirically Based Phenotypic Profiles of Children with Pervasive Developmental Disorders: Interpretation in the Light of the DSM-5 Type de document : texte imprimé Auteurs : Kirstin GREAVES-LORD, Auteur ; Mart L.J.M. EUSSEN, Auteur ; Frank C. VERHULST, Auteur ; Ruud B. MINDERAA, Auteur ; William MANDY, Auteur ; James J. HUDZIAK, Auteur ; Mark Peter STEENHUIS, Auteur ; Pieter F.A. DE NIJS, Auteur ; Catharina A. HARTMAN, Auteur Article en page(s) : p.1784-1797 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  DSM-5  Phenotypic profiles  Comorbidity Index. décimale : PER Périodiques Résumé : This study aimed to contribute to the Diagnostic and Statistical Manual (DSM) debates on the conceptualization of autism by investigating (1) whether empirically based distinct phenotypic profiles could be distinguished within a sample of mainly cognitively able children with pervasive developmental disorder (PDD), and (2) how profiles related to diagnoses and co-occurring behavioral and emotional problems. Six classes with distinct profiles were discerned. Three classes showed profiles not completely in line with the proposed DSM-5 conceptualization of autism. These classes included relatively many cognitively able individuals with PDD-not otherwise specified. However, profiles seemed to suit other diagnostic categories, such as social communication disorder. These alternative diagnoses could retain eligibility for services, and might adequately fit more specifically targeted interventions. En ligne : http://dx.doi.org/10.1007/s10803-012-1724-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=205 [article] Empirically Based Phenotypic Profiles of Children with Pervasive Developmental Disorders: Interpretation in the Light of the DSM-5 [texte imprimé] / Kirstin GREAVES-LORD, Auteur ; Mart L.J.M. EUSSEN, Auteur ; Frank C. VERHULST, Auteur ; Ruud B. MINDERAA, Auteur ; William MANDY, Auteur ; James J. HUDZIAK, Auteur ; Mark Peter STEENHUIS, Auteur ; Pieter F.A. DE NIJS, Auteur ; Catharina A. HARTMAN, Auteur . - p.1784-1797. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-8 (August 2013) . - p.1784-1797 Mots-clés : Autism spectrum disorders  DSM-5  Phenotypic profiles  Comorbidity Index. décimale : PER Périodiques Résumé : This study aimed to contribute to the Diagnostic and Statistical Manual (DSM) debates on the conceptualization of autism by investigating (1) whether empirically based distinct phenotypic profiles could be distinguished within a sample of mainly cognitively able children with pervasive developmental disorder (PDD), and (2) how profiles related to diagnoses and co-occurring behavioral and emotional problems. Six classes with distinct profiles were discerned. Three classes showed profiles not completely in line with the proposed DSM-5 conceptualization of autism. These classes included relatively many cognitively able individuals with PDD-not otherwise specified. However, profiles seemed to suit other diagnostic categories, such as social communication disorder. These alternative diagnoses could retain eligibility for services, and might adequately fit more specifically targeted interventions. En ligne : http://dx.doi.org/10.1007/s10803-012-1724-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=205

The association of quality of social relations, symptom severity and intelligence with anxiety in children with autism spectrum disorders / Mart L.J.M. EUSSEN in Autism, 17-6 (November 2013)  

Public ISBD [article]  inAutism > 17-6 (November 2013) . - p.723-735 Titre : The association of quality of social relations, symptom severity and intelligence with anxiety in children with autism spectrum disorders Type de document : texte imprimé Auteurs : Mart L.J.M. EUSSEN, Auteur ; Arthur R. VAN GOOL, Auteur ; Fop VERHEIJ, Auteur ; Pieter F.A. DE NIJS, Auteur ; Frank C. VERHULST, Auteur ; Kirstin GREAVES-LORD, Auteur Année de publication : 2013 Article en page(s) : p.723-735 Langues : Anglais (eng) Mots-clés : anxiety  autism spectrum disorders  intelligence  social relations  symptom severity Index. décimale : PER Périodiques Résumé : Limited quality of social relations, milder symptom severity and higher intelligence were shown to account for higher anxiety levels in autism spectrum disorders. The current study replicated and extended earlier findings by combining these three determinants of anxiety in autism spectrum disorders in one study. The sample consisted of 134 school-aged children with autism spectrum disorders, of whom 58 (43%) had a co-morbid anxiety disorder according to the Diagnostic Interview Schedule for Children–Parent version. In this sample, we tested associations between these determinants and anxiety univariately and multivariately to clarify the unique contribution of all determinants. Since we hypothesized that the association between limited quality of social relations and anxiety would be amplified by low symptom severity and/or high intelligence, we additionally tested for moderating effects. We found that higher anxiety levels were associated with a lower quality of social relations and lower symptom severity. In this mainly high-functioning sample, intelligence was not related to anxiety levels. No moderation effects were found. Since lower quality of social relations and lower symptom severity are associated with higher anxiety levels in children with autism spectrum disorders, therapeutic interventions aimed at reducing anxiety in autism spectrum disorders should pay attention to improving social relations, and presumably children with a lower symptom severity could benefit most from such interventions. En ligne : http://dx.doi.org/10.1177/1362361312453882 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218 [article] The association of quality of social relations, symptom severity and intelligence with anxiety in children with autism spectrum disorders [texte imprimé] / Mart L.J.M. EUSSEN, Auteur ; Arthur R. VAN GOOL, Auteur ; Fop VERHEIJ, Auteur ; Pieter F.A. DE NIJS, Auteur ; Frank C. VERHULST, Auteur ; Kirstin GREAVES-LORD, Auteur . - 2013 . - p.723-735. Langues : Anglais (eng) in Autism > 17-6 (November 2013) . - p.723-735 Mots-clés : anxiety  autism spectrum disorders  intelligence  social relations  symptom severity Index. décimale : PER Périodiques Résumé : Limited quality of social relations, milder symptom severity and higher intelligence were shown to account for higher anxiety levels in autism spectrum disorders. The current study replicated and extended earlier findings by combining these three determinants of anxiety in autism spectrum disorders in one study. The sample consisted of 134 school-aged children with autism spectrum disorders, of whom 58 (43%) had a co-morbid anxiety disorder according to the Diagnostic Interview Schedule for Children–Parent version. In this sample, we tested associations between these determinants and anxiety univariately and multivariately to clarify the unique contribution of all determinants. Since we hypothesized that the association between limited quality of social relations and anxiety would be amplified by low symptom severity and/or high intelligence, we additionally tested for moderating effects. We found that higher anxiety levels were associated with a lower quality of social relations and lower symptom severity. In this mainly high-functioning sample, intelligence was not related to anxiety levels. No moderation effects were found. Since lower quality of social relations and lower symptom severity are associated with higher anxiety levels in children with autism spectrum disorders, therapeutic interventions aimed at reducing anxiety in autism spectrum disorders should pay attention to improving social relations, and presumably children with a lower symptom severity could benefit most from such interventions. En ligne : http://dx.doi.org/10.1177/1362361312453882 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218

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