Anxiety moderates the influence of ASD severity on quality of life in adults with ASD / Isaac C. SMITH in Research in Autism Spectrum Disorders, 62 (June 2019)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 62 (June 2019) . - p.39-47 Titre : Anxiety moderates the influence of ASD severity on quality of life in adults with ASD Type de document : Texte imprimé et/ou numérique Auteurs : Isaac C. SMITH, Auteur ; Thomas H. OLLENDICK, Auteur ; Susan W. WHITE, Auteur Article en page(s) : p.39-47 Langues : Anglais (eng) Mots-clés : Autism  Anxiety  Adult  Quality of life  Comorbidity Index. décimale : PER Périodiques Résumé : Background Comorbidity of anxiety and autism spectrum disorder (ASD) in children and adolescents is well-documented. Preliminary evidence suggests rates of comorbidity in adults with ASD may be comparable. Little is known about the manifestation of anxiety symptoms in adults with ASD or the potential for these symptoms to impact quality of life in this population. The current study aimed to examine the role of anxiety symptoms in quality of life among young adults with ASD. Method We collected online survey data from a large sample (N = 224) of parents of young adults with ASD and a subsample of adults with ASD. We examined prevalence of anxiety symptoms based on reported prior diagnoses and proportion of individuals exceeding clinical cutoffs on anxiety measures. Regression models were used to evaluate anxiety as a moderator of the relationship between ASD symptoms and quality of life. Results Based on parent- and self-report data, 48% of adults with ASD exceeded clinical cutoffs for anxiety. Anxiety moderated the relationship between ASD severity and the social relations domain of quality of life such that ASD severity predicted quality of life only among individuals with low levels of anxiety. Conclusions Results provide preliminary evidence that anxiety symptoms relate to quality of life in adults with ASD independently of core ASD symptomatology. Future research should further characterize anxiety symptoms among adults with ASD, as well as evaluate the impact of anxiety symptoms on quality of life and overall outcome through the use of prospective longitudinal studies. En ligne : https://doi.org/10.1016/j.rasd.2019.03.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=389 [article] Anxiety moderates the influence of ASD severity on quality of life in adults with ASD [Texte imprimé et/ou numérique] / Isaac C. SMITH, Auteur ; Thomas H. OLLENDICK, Auteur ; Susan W. WHITE, Auteur . - p.39-47. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 62 (June 2019) . - p.39-47 Mots-clés : Autism  Anxiety  Adult  Quality of life  Comorbidity Index. décimale : PER Périodiques Résumé : Background Comorbidity of anxiety and autism spectrum disorder (ASD) in children and adolescents is well-documented. Preliminary evidence suggests rates of comorbidity in adults with ASD may be comparable. Little is known about the manifestation of anxiety symptoms in adults with ASD or the potential for these symptoms to impact quality of life in this population. The current study aimed to examine the role of anxiety symptoms in quality of life among young adults with ASD. Method We collected online survey data from a large sample (N = 224) of parents of young adults with ASD and a subsample of adults with ASD. We examined prevalence of anxiety symptoms based on reported prior diagnoses and proportion of individuals exceeding clinical cutoffs on anxiety measures. Regression models were used to evaluate anxiety as a moderator of the relationship between ASD symptoms and quality of life. Results Based on parent- and self-report data, 48% of adults with ASD exceeded clinical cutoffs for anxiety. Anxiety moderated the relationship between ASD severity and the social relations domain of quality of life such that ASD severity predicted quality of life only among individuals with low levels of anxiety. Conclusions Results provide preliminary evidence that anxiety symptoms relate to quality of life in adults with ASD independently of core ASD symptomatology. Future research should further characterize anxiety symptoms among adults with ASD, as well as evaluate the impact of anxiety symptoms on quality of life and overall outcome through the use of prospective longitudinal studies. En ligne : https://doi.org/10.1016/j.rasd.2019.03.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=389

Brief Report: Systematic Review of Rett Syndrome in Males / Brian REICHOW in Journal of Autism and Developmental Disorders, 45-10 (October 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-10 (October 2015) . - p.3377-3383 Titre : Brief Report: Systematic Review of Rett Syndrome in Males Type de document : Texte imprimé et/ou numérique Auteurs : Brian REICHOW, Auteur ; Annie GEORGE-PUSKAR, Auteur ; Tara LUTZ, Auteur ; Isaac C. SMITH, Auteur ; Fred R. VOLKMAR, Auteur Article en page(s) : p.3377-3383 Langues : Anglais (eng) Mots-clés : Rett syndrome  Rett’s syndrome  RTT  Male  Boy Index. décimale : PER Périodiques Résumé : Rett syndrome (RTT) is a neurogenetic disorder in which a period of typical development is followed by loss of previously acquired skills. Once thought to occur exclusively in females, increasing numbers of male cases of RTT have been reported. This systematic review included 36 articles describing 57 cases of RTT in males. Mutations of the MECP2 gene were present in 56 % of cases, and 68 % of cases reported other genetic abnormalities. This is the first review of published reports of RTT in male patients. En ligne : http://dx.doi.org/10.1007/s10803-015-2519-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268 [article] Brief Report: Systematic Review of Rett Syndrome in Males [Texte imprimé et/ou numérique] / Brian REICHOW, Auteur ; Annie GEORGE-PUSKAR, Auteur ; Tara LUTZ, Auteur ; Isaac C. SMITH, Auteur ; Fred R. VOLKMAR, Auteur . - p.3377-3383. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-10 (October 2015) . - p.3377-3383 Mots-clés : Rett syndrome  Rett’s syndrome  RTT  Male  Boy Index. décimale : PER Périodiques Résumé : Rett syndrome (RTT) is a neurogenetic disorder in which a period of typical development is followed by loss of previously acquired skills. Once thought to occur exclusively in females, increasing numbers of male cases of RTT have been reported. This systematic review included 36 articles describing 57 cases of RTT in males. Mutations of the MECP2 gene were present in 56 % of cases, and 68 % of cases reported other genetic abnormalities. This is the first review of published reports of RTT in male patients. En ligne : http://dx.doi.org/10.1007/s10803-015-2519-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268

Development of a College Transition and Support Program for Students with Autism Spectrum Disorder / Susan W. WHITE in Journal of Autism and Developmental Disorders, 47-10 (October 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-10 (October 2017) . - p.3072-3078 Titre : Development of a College Transition and Support Program for Students with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Susan W. WHITE, Auteur ; Rebecca ELIAS, Auteur ; Nicole N. CAPRIOLA-HALL, Auteur ; Isaac C. SMITH, Auteur ; Caitlin M. CONNER, Auteur ; Susan B. ASSELIN, Auteur ; Patricia HOWLIN, Auteur ; Elizabeth E. GETZEL, Auteur ; Carla A. MAZEFSKY, Auteur Article en page(s) : p.3072-3078 Langues : Anglais (eng) Mots-clés : Autism  College  Transition  Adult Index. décimale : PER Périodiques Résumé : Empirically based, consumer-informed programming to support students with Autism Spectrum Disorder (ASD) transitioning to college is needed. Informed by theory and research, the Stepped Transition in Education Program for Students with ASD (STEPS) was developed to address this need. The first level (Step 1) supports high school students and the second level (Step 2) is for postsecondary students with ASD. Herein, we review the extant research on transition supports for emerging adults with ASD and describe the development of STEPS, including its theoretical basis and how it was informed by consumer input. The impact of STEPS on promotion of successful transition into college and positive outcomes for students during higher education is currently being evaluated in a randomized controlled trial. En ligne : https://doi.org/10.1007/s10803-017-3236-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=319 [article] Development of a College Transition and Support Program for Students with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Susan W. WHITE, Auteur ; Rebecca ELIAS, Auteur ; Nicole N. CAPRIOLA-HALL, Auteur ; Isaac C. SMITH, Auteur ; Caitlin M. CONNER, Auteur ; Susan B. ASSELIN, Auteur ; Patricia HOWLIN, Auteur ; Elizabeth E. GETZEL, Auteur ; Carla A. MAZEFSKY, Auteur . - p.3072-3078. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-10 (October 2017) . - p.3072-3078 Mots-clés : Autism  College  Transition  Adult Index. décimale : PER Périodiques Résumé : Empirically based, consumer-informed programming to support students with Autism Spectrum Disorder (ASD) transitioning to college is needed. Informed by theory and research, the Stepped Transition in Education Program for Students with ASD (STEPS) was developed to address this need. The first level (Step 1) supports high school students and the second level (Step 2) is for postsecondary students with ASD. Herein, we review the extant research on transition supports for emerging adults with ASD and describe the development of STEPS, including its theoretical basis and how it was informed by consumer input. The impact of STEPS on promotion of successful transition into college and positive outcomes for students during higher education is currently being evaluated in a randomized controlled trial. En ligne : https://doi.org/10.1007/s10803-017-3236-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=319

Emotion regulation and executive function: Associations with depression and anxiety in autism / Caitlin M. CONNER in Research in Autism Spectrum Disorders, 101 (March 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 101 (March 2023) . - 102103 Titre : Emotion regulation and executive function: Associations with depression and anxiety in autism Type de document : Texte imprimé et/ou numérique Auteurs : Caitlin M. CONNER, Auteur ; Rebecca ELIAS, Auteur ; Isaac C. SMITH, Auteur ; Susan W. WHITE, Auteur Article en page(s) : 102103 Langues : Anglais (eng) Mots-clés : Emotion regulation  Executive functioning  Depression  Anxiety  Cognitive flexibility  Inhibition Index. décimale : PER Périodiques Résumé : Background Adolescents and young adults with autism spectrum disorder (ASD) are prone to experience co-occurring mental health conditions such as mood or anxiety disorders, as well as impairments in emotion regulation and executive functioning. However, little research has examined inter-relationships among these constructs, despite evidence of additional stressors and increased risk of internalizing disorders at this age, relative to non-autistic individuals. If either emotion regulation or executive functioning are shown to have patterns of association with mental health, this can inform mechanism-based intervention. Method Fifty-seven autistic adolescents and adults (16 “25 years) with ASD in a transition intervention completed questionnaires and clinician-administered measures at baseline. Analyses assessed whether executive functioning impairment, above and beyond emotion regulation impairment, were associated with depression and anxiety symptoms. Results ASD characteristics, emotion regulation, anxiety, and depression were significantly correlated. ASD characteristics was a significant contributor to depression and emotion regulation impairments were significant contributors to anxiety and depression. Findings indicated that inhibition difficulties did not uniquely contribute to depression or anxiety above emotion regulation impairment. Difficulties in cognitive flexibility were associated with depression above and beyond ASD characteristics, IQ, and emotion regulation, but not associated with anxiety. Conclusions Although preliminary, findings suggest that inflexibility and regulatory impairment should be considered in depression remediation approaches. Improving ER, on the other hand, may have broader transdiagnostic impact across both mood and anxiety symptoms in ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102103 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 [article] Emotion regulation and executive function: Associations with depression and anxiety in autism [Texte imprimé et/ou numérique] / Caitlin M. CONNER, Auteur ; Rebecca ELIAS, Auteur ; Isaac C. SMITH, Auteur ; Susan W. WHITE, Auteur . - 102103. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 101 (March 2023) . - 102103 Mots-clés : Emotion regulation  Executive functioning  Depression  Anxiety  Cognitive flexibility  Inhibition Index. décimale : PER Périodiques Résumé : Background Adolescents and young adults with autism spectrum disorder (ASD) are prone to experience co-occurring mental health conditions such as mood or anxiety disorders, as well as impairments in emotion regulation and executive functioning. However, little research has examined inter-relationships among these constructs, despite evidence of additional stressors and increased risk of internalizing disorders at this age, relative to non-autistic individuals. If either emotion regulation or executive functioning are shown to have patterns of association with mental health, this can inform mechanism-based intervention. Method Fifty-seven autistic adolescents and adults (16 “25 years) with ASD in a transition intervention completed questionnaires and clinician-administered measures at baseline. Analyses assessed whether executive functioning impairment, above and beyond emotion regulation impairment, were associated with depression and anxiety symptoms. Results ASD characteristics, emotion regulation, anxiety, and depression were significantly correlated. ASD characteristics was a significant contributor to depression and emotion regulation impairments were significant contributors to anxiety and depression. Findings indicated that inhibition difficulties did not uniquely contribute to depression or anxiety above emotion regulation impairment. Difficulties in cognitive flexibility were associated with depression above and beyond ASD characteristics, IQ, and emotion regulation, but not associated with anxiety. Conclusions Although preliminary, findings suggest that inflexibility and regulatory impairment should be considered in depression remediation approaches. Improving ER, on the other hand, may have broader transdiagnostic impact across both mood and anxiety symptoms in ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102103 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492

Perspectives d’avenir dans l’évaluation et le traitement des troubles du spectre de l’autisme / Isaac C. SMITH

Public ISBD in Evaluer les troubles du spectre de l'autisme / Sam GOLDSTEIN Titre : Perspectives d’avenir dans l’évaluation et le traitement des troubles du spectre de l’autisme Type de document : Texte imprimé et/ou numérique Auteurs : Isaac C. SMITH, Auteur ; Cara E. PUGLIESE, Auteur ; Blythe A. CORBETT, Auteur ; Susan W. WHITE, Auteur Année de publication : 2020 Importance : p.319-343 Langues : Français (fre) Index. décimale : AUT-D AUT-D - L'Autisme - Dépistage et Diagnostic Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435 in Evaluer les troubles du spectre de l'autisme / Sam GOLDSTEIN Perspectives d’avenir dans l’évaluation et le traitement des troubles du spectre de l’autisme [Texte imprimé et/ou numérique] / Isaac C. SMITH, Auteur ; Cara E. PUGLIESE, Auteur ; Blythe A. CORBETT, Auteur ; Susan W. WHITE, Auteur . - 2020 . - p.319-343. Langues : Français (fre) Index. décimale : AUT-D AUT-D - L'Autisme - Dépistage et Diagnostic Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435

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The Effects of DSM-5 Criteria on Number of Individuals Diagnosed with Autism Spectrum Disorder: A Systematic Review / Isaac C. SMITH in Journal of Autism and Developmental Disorders, 45-8 (August 2015)  

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