Alexithymia in Parents of Children with Autism Spectrum Disorder / Peter SZATMARI in Journal of Autism and Developmental Disorders, 38-10 (November 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-10 (November 2008) . - p.1859-1865 Titre : Alexithymia in Parents of Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Peter SZATMARI, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Stelios GEORGIADES, Auteur ; Jeremy GOLDBERG, Auteur ; Terry BENNETT, Auteur ; Eric DUKU, Auteur Année de publication : 2008 Article en page(s) : p.1859-1865 Langues : Anglais (eng) Mots-clés : Autism Broader-autism-phenotype Emotion-processing Alexithymia Intermediate-phenotype Index. décimale : PER Périodiques Résumé : Given the recent findings regarding the association between alexithymia and Autism Spectrum Disorder (ASD) and the accumulating evidence for the presence of the Broader Autism Phenotype (BAP) in relatives of individuals with ASD, we further explored the construct of alexithymia in parents of children with ASD as a potential part of the BAP. We hypothesized that (a) parents of children with ASD will demonstrate higher impairment in their emotion processing when compared to controls, and (b) high impairment in emotion processing in parents will be associated with severity of symptoms in children with ASD. Psychometric and diagnostic data were collected on 188 children with a diagnosis of ASD. The Toronto Alexithymia Scale (TAS-20) was completed by 439 parents of children with ASD and a control group of 45 parents of children with Prader Willi syndrome (PW). Results show that ASD parents score higher than controls on the TAS-20 total score. Within the ASD group, children of fathers with high alexithymia score higher on repetitive behaviour symptoms compared to children of fathers with low alexithymia. The alexithymia trait appears to be one of the many building blocks that make up the BAP. En ligne : http://dx.doi.org/10.1007/s10803-008-0576-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=641 [article] Alexithymia in Parents of Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Peter SZATMARI, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Stelios GEORGIADES, Auteur ; Jeremy GOLDBERG, Auteur ; Terry BENNETT, Auteur ; Eric DUKU, Auteur . - 2008 . - p.1859-1865. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-10 (November 2008) . - p.1859-1865 Mots-clés : Autism Broader-autism-phenotype Emotion-processing Alexithymia Intermediate-phenotype Index. décimale : PER Périodiques Résumé : Given the recent findings regarding the association between alexithymia and Autism Spectrum Disorder (ASD) and the accumulating evidence for the presence of the Broader Autism Phenotype (BAP) in relatives of individuals with ASD, we further explored the construct of alexithymia in parents of children with ASD as a potential part of the BAP. We hypothesized that (a) parents of children with ASD will demonstrate higher impairment in their emotion processing when compared to controls, and (b) high impairment in emotion processing in parents will be associated with severity of symptoms in children with ASD. Psychometric and diagnostic data were collected on 188 children with a diagnosis of ASD. The Toronto Alexithymia Scale (TAS-20) was completed by 439 parents of children with ASD and a control group of 45 parents of children with Prader Willi syndrome (PW). Results show that ASD parents score higher than controls on the TAS-20 total score. Within the ASD group, children of fathers with high alexithymia score higher on repetitive behaviour symptoms compared to children of fathers with low alexithymia. The alexithymia trait appears to be one of the many building blocks that make up the BAP. En ligne : http://dx.doi.org/10.1007/s10803-008-0576-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=641

Differentiating Autism and Asperger Syndrome on the Basis of Language Delay or Impairment / Terry BENNETT in Journal of Autism and Developmental Disorders, 38-4 (April 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-4 (April 2008) . - p.616-625 Titre : Differentiating Autism and Asperger Syndrome on the Basis of Language Delay or Impairment Type de document : Texte imprimé et/ou numérique Auteurs : Terry BENNETT, Auteur ; Susan E. BRYSON, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Peter SZATMARI, Auteur ; Michael H. BOYLE, Auteur ; Joanne VOLDEN, Auteur ; Liezanne VACCARELLA, Auteur ; Eric DUKU, Auteur Année de publication : 2008 Article en page(s) : p.616-625 Langues : Anglais (eng) Mots-clés : Autism Asperger-syndrome Language-impairment Outcomes Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) is differentiated from high-functioning autism (HFA) largely on a history of “language delay.” This study examined “specific language impairment” as a predictor of outcome. Language skills of 19 children with AS and 45 with HFA were assessed at 4–6 years of age (Time 1) and 2 years later (Time 2). Children’s symptoms and functional outcome scores were assessed every 2 years (Times 3, 4, and 5) until ages 15–17 years old. Regression analysis revealed that specific language impairment at time 2 more often accounted for the greatest variation in outcome scores in adolescence than the standard diagnosis of AS versus HFA based on history of language delay. Diagnostic implications are discussed. En ligne : http://dx.doi.org/10.1007/s10803-007-0428-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=340 [article] Differentiating Autism and Asperger Syndrome on the Basis of Language Delay or Impairment [Texte imprimé et/ou numérique] / Terry BENNETT, Auteur ; Susan E. BRYSON, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Peter SZATMARI, Auteur ; Michael H. BOYLE, Auteur ; Joanne VOLDEN, Auteur ; Liezanne VACCARELLA, Auteur ; Eric DUKU, Auteur . - 2008 . - p.616-625. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-4 (April 2008) . - p.616-625 Mots-clés : Autism Asperger-syndrome Language-impairment Outcomes Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) is differentiated from high-functioning autism (HFA) largely on a history of “language delay.” This study examined “specific language impairment” as a predictor of outcome. Language skills of 19 children with AS and 45 with HFA were assessed at 4–6 years of age (Time 1) and 2 years later (Time 2). Children’s symptoms and functional outcome scores were assessed every 2 years (Times 3, 4, and 5) until ages 15–17 years old. Regression analysis revealed that specific language impairment at time 2 more often accounted for the greatest variation in outcome scores in adolescence than the standard diagnosis of AS versus HFA based on history of language delay. Diagnostic implications are discussed. En ligne : http://dx.doi.org/10.1007/s10803-007-0428-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=340

Measurement equivalence of the autism symptom phenotype in children and youth / Eric DUKU in Journal of Child Psychology and Psychiatry, 54-12 (December 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1346-1355 Titre : Measurement equivalence of the autism symptom phenotype in children and youth Type de document : Texte imprimé et/ou numérique Auteurs : Eric DUKU, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Stelios GEORGIADES, Auteur ; Ann THOMPSON, Auteur ; Xiao-Qing LIU, Auteur ; Andrew D. PATERSON, Auteur ; Terry BENNETT, Auteur Article en page(s) : p.1346-1355 Langues : Anglais (eng) Mots-clés : Autism Diagnostic Interview-Revised  measurement equivalence  autism spectrum disorder  confirmatory factor analysis  structural equation modelling Index. décimale : PER Périodiques Résumé : Background The Autism Diagnostic Interview-Revised (ADI-R) is a gold standard assessment of Autism Spectrum Disorder (ASD) symptoms and behaviours. A key underlying assumption of studies using the ADI-R is that it measures the same phenotypic constructs across different populations (i.e. males/females, younger/older, verbal/nonverbal). The objectives of this study were to evaluate alternative measurement models for the autism symptom phenotype based on the ADI-R algorithm items and to examine the measurement equivalence of the most parsimonious and best fitting model across subgroups of interest. Methods Data came from the Autism Genome Project consortium and consisted of 3,628 children aged 4–18 years (84.2% boys and 75% verbal). Twenty-eight algorithm items applicable to both verbal and nonverbal participants were used in the analysis. Measurement equivalence of the autism phenotype was examined using categorical confirmatory factor analysis. Results A second-order model resembling the proposed DSM-5 two-factor structure of the phenotype showed good overall fit, but not for all the subgroups. The autism symptom phenotype was best indexed by the first-order, six-factor measurement model proposed by Liu et al. (2011). This model was well fitting and measurement equivalent across subgroups of participants (age, verbal ability and sex). Conclusions The autism symptom phenotype is adequately characterized by a six-factor measurement model; this model appears to be measurement equivalent across subgroups of children and youth with ASD that differ in age, sex and verbal ability. The two-factor model provides equally good fit for the sample as a whole, but comparison of these two dimensions between subgroups that might differ in terms of age, sex or verbal ability is challenged by lack of measurement equivalence. En ligne : http://dx.doi.org/10.1111/jcpp.12103 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219 [article] Measurement equivalence of the autism symptom phenotype in children and youth [Texte imprimé et/ou numérique] / Eric DUKU, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Stelios GEORGIADES, Auteur ; Ann THOMPSON, Auteur ; Xiao-Qing LIU, Auteur ; Andrew D. PATERSON, Auteur ; Terry BENNETT, Auteur . - p.1346-1355. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1346-1355 Mots-clés : Autism Diagnostic Interview-Revised  measurement equivalence  autism spectrum disorder  confirmatory factor analysis  structural equation modelling Index. décimale : PER Périodiques Résumé : Background The Autism Diagnostic Interview-Revised (ADI-R) is a gold standard assessment of Autism Spectrum Disorder (ASD) symptoms and behaviours. A key underlying assumption of studies using the ADI-R is that it measures the same phenotypic constructs across different populations (i.e. males/females, younger/older, verbal/nonverbal). The objectives of this study were to evaluate alternative measurement models for the autism symptom phenotype based on the ADI-R algorithm items and to examine the measurement equivalence of the most parsimonious and best fitting model across subgroups of interest. Methods Data came from the Autism Genome Project consortium and consisted of 3,628 children aged 4–18 years (84.2% boys and 75% verbal). Twenty-eight algorithm items applicable to both verbal and nonverbal participants were used in the analysis. Measurement equivalence of the autism phenotype was examined using categorical confirmatory factor analysis. Results A second-order model resembling the proposed DSM-5 two-factor structure of the phenotype showed good overall fit, but not for all the subgroups. The autism symptom phenotype was best indexed by the first-order, six-factor measurement model proposed by Liu et al. (2011). This model was well fitting and measurement equivalent across subgroups of participants (age, verbal ability and sex). Conclusions The autism symptom phenotype is adequately characterized by a six-factor measurement model; this model appears to be measurement equivalent across subgroups of children and youth with ASD that differ in age, sex and verbal ability. The two-factor model provides equally good fit for the sample as a whole, but comparison of these two dimensions between subgroups that might differ in terms of age, sex or verbal ability is challenged by lack of measurement equivalence. En ligne : http://dx.doi.org/10.1111/jcpp.12103 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219

Predictors of longer-term development of expressive language in two independent longitudinal cohorts of language-delayed preschoolers with Autism Spectrum Disorder / Vanessa H. BAL in Journal of Child Psychology and Psychiatry, 61-7 (July 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-7 (July 2020) . - p.826-835 Titre : Predictors of longer-term development of expressive language in two independent longitudinal cohorts of language-delayed preschoolers with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Vanessa H. BAL, Auteur ; Megan FOK, Auteur ; Catherine LORD, Auteur ; Isabel M SMITH, Auteur ; Pat MIRENDA, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Terry BENNETT, Auteur ; Eric DUKU, Auteur ; Mayada ELSABBAGH, Auteur ; Stelios GEORGIADES, Auteur ; Wendy J. UNGAR, Auteur ; Anat ZAIDMAN-ZAIT, Auteur Article en page(s) : p.826-835 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  language  longitudinal studies  motor skills  conflicts of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Studies estimate that 30% of individuals with autism are minimally verbal. Understanding what factors predict longer-term expressive development in children with language delays is critical to inform identification and treatment of those at-risk for persistent language impairments. The present study examined predictors of expressive language development in language-delayed preschoolers followed through later school-age and young adulthood. METHODS: Children using single words or less on the Autism Diagnostic Observation Schedule (ADOS) at approximately 3 years old were drawn from the Early Diagnosis (EDX) and Pathways in ASD longitudinal cohorts. Age-3 predictors of Age-19 ADOS language level were identified using Classification and Regression Trees (CART) in the EDX sample. Linear mixed models examined the effects of CART-identified predictors on Vineland expressive communication (VExp) trajectories from Age-3 to Age-19. The same linear mixed models were examined in the Pathways sample, identifying predictors of VExp from ages 3 to 10.5 years. RESULTS: Significantly delayed fine motor skills (T-score < 20) was the strongest CART predictor of Age-19 language. In the linear mixed models, time, Age-3 fine motor skills and initiation of joint attention (IJA) predicted VExp trajectories in the EDX sample, even when controlling for Age-3 visual receptive abilities. In the Pathways sample, time and Age-3 fine motor skills were significant predictors of VExp trajectories; IJA and cognitive skills were not significant predictors. CONCLUSIONS: Marked deficits in fine motor skills may be a salient proxy marker for identifying language-delayed children with ASD who are at risk for persistent language impairments. This finding adds to the literature demonstrating a relation between motor and language development in ASD. Investigating individual skill areas (e.g., fine motor and nonverbal problem-solving skills), rather than broader indices of developmental level (e.g., nonverbal IQ) may provide important cues to understanding longer-term language outcomes that can be targeted in early intervention. En ligne : http://dx.doi.org/10.1111/jcpp.13117 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429 [article] Predictors of longer-term development of expressive language in two independent longitudinal cohorts of language-delayed preschoolers with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Vanessa H. BAL, Auteur ; Megan FOK, Auteur ; Catherine LORD, Auteur ; Isabel M SMITH, Auteur ; Pat MIRENDA, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Joanne VOLDEN, Auteur ; Charlotte WADDELL, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Terry BENNETT, Auteur ; Eric DUKU, Auteur ; Mayada ELSABBAGH, Auteur ; Stelios GEORGIADES, Auteur ; Wendy J. UNGAR, Auteur ; Anat ZAIDMAN-ZAIT, Auteur . - p.826-835. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-7 (July 2020) . - p.826-835 Mots-clés : Autism spectrum disorder  language  longitudinal studies  motor skills  conflicts of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Studies estimate that 30% of individuals with autism are minimally verbal. Understanding what factors predict longer-term expressive development in children with language delays is critical to inform identification and treatment of those at-risk for persistent language impairments. The present study examined predictors of expressive language development in language-delayed preschoolers followed through later school-age and young adulthood. METHODS: Children using single words or less on the Autism Diagnostic Observation Schedule (ADOS) at approximately 3 years old were drawn from the Early Diagnosis (EDX) and Pathways in ASD longitudinal cohorts. Age-3 predictors of Age-19 ADOS language level were identified using Classification and Regression Trees (CART) in the EDX sample. Linear mixed models examined the effects of CART-identified predictors on Vineland expressive communication (VExp) trajectories from Age-3 to Age-19. The same linear mixed models were examined in the Pathways sample, identifying predictors of VExp from ages 3 to 10.5 years. RESULTS: Significantly delayed fine motor skills (T-score < 20) was the strongest CART predictor of Age-19 language. In the linear mixed models, time, Age-3 fine motor skills and initiation of joint attention (IJA) predicted VExp trajectories in the EDX sample, even when controlling for Age-3 visual receptive abilities. In the Pathways sample, time and Age-3 fine motor skills were significant predictors of VExp trajectories; IJA and cognitive skills were not significant predictors. CONCLUSIONS: Marked deficits in fine motor skills may be a salient proxy marker for identifying language-delayed children with ASD who are at risk for persistent language impairments. This finding adds to the literature demonstrating a relation between motor and language development in ASD. Investigating individual skill areas (e.g., fine motor and nonverbal problem-solving skills), rather than broader indices of developmental level (e.g., nonverbal IQ) may provide important cues to understanding longer-term language outcomes that can be targeted in early intervention. En ligne : http://dx.doi.org/10.1111/jcpp.13117 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=429

The Influence of Bilingual Language Exposure on the Narrative, Social and Pragmatic Abilities of School-Aged Children on the Autism Spectrum / Stefano REZZONICO ; Terry BENNETT ; Eric DUKU ; Stelios GEORGIADES ; Connor KERNS ; Pat MIRENDA ; Annie RICHARD ; Isabel M. SMITH ; Peter SZATMARI ; Tracy VAILLANCOURT ; Charlotte WADDELL ; Anat ZAIDMAN-ZAIT ; Lonnie ZWAIGENBAUM ; Mayada ELSABBAGH in Journal of Autism and Developmental Disorders, 53-12 (December 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-12 (December 2023) . - p.4577-4590 Titre : The Influence of Bilingual Language Exposure on the Narrative, Social and Pragmatic Abilities of School-Aged Children on the Autism Spectrum Type de document : Texte imprimé et/ou numérique Auteurs : Stefano REZZONICO, Auteur ; Terry BENNETT, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Connor KERNS, Auteur ; Pat MIRENDA, Auteur ; Annie RICHARD, Auteur ; Isabel M. SMITH, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Charlotte WADDELL, Auteur ; Anat ZAIDMAN-ZAIT, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Mayada ELSABBAGH, Auteur Article en page(s) : p.4577-4590 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : We examined the narrative abilities of bilingual and monolingual children on the autism spectrum (AS), whether bilinguals presented stronger social and pragmatic language abilities compared to monolinguals, and the link between narrative, social, and pragmatic language abilities. En ligne : https://doi.org/10.1007/s10803-022-05678-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515 [article] The Influence of Bilingual Language Exposure on the Narrative, Social and Pragmatic Abilities of School-Aged Children on the Autism Spectrum [Texte imprimé et/ou numérique] / Stefano REZZONICO, Auteur ; Terry BENNETT, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Connor KERNS, Auteur ; Pat MIRENDA, Auteur ; Annie RICHARD, Auteur ; Isabel M. SMITH, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Charlotte WADDELL, Auteur ; Anat ZAIDMAN-ZAIT, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Mayada ELSABBAGH, Auteur . - p.4577-4590. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-12 (December 2023) . - p.4577-4590 Index. décimale : PER Périodiques Résumé : We examined the narrative abilities of bilingual and monolingual children on the autism spectrum (AS), whether bilinguals presented stronger social and pragmatic language abilities compared to monolinguals, and the link between narrative, social, and pragmatic language abilities. En ligne : https://doi.org/10.1007/s10803-022-05678-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515

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