Examining the bidirectional association between emotion recognition and social autistic traits using observational and genetic analyses / Z. E. REED in Journal of Child Psychology and Psychiatry, 62-11 (November 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-11 (November 2021) . - p.1330-1338 Titre : Examining the bidirectional association between emotion recognition and social autistic traits using observational and genetic analyses Type de document : Texte imprimé et/ou numérique Auteurs : Z. E. REED, Auteur ; L. MAHEDY, Auteur ; A. JACKSON, Auteur ; George DAVEY SMITH, Auteur ; I. PENTON-VOAK, Auteur ; A. S. ATTWOOD, Auteur ; M. R. MUNAFO, Auteur Article en page(s) : p.1330-1338 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder/genetics  Autistic Disorder  Child  Emotions  Humans  Longitudinal Studies  Parents  Young Adult  Alspac  Autism spectrum disorder  emotion recognition  polygenic risk score  social autistic traits Index. décimale : PER Périodiques Résumé : BACKGROUND: There is mixed evidence for an association between autism spectrum disorder (ASD) and emotion recognition deficits. We sought to assess the bidirectionality of this association using phenotypic and genetic data in a large community sample. METHODS: Analyses were conducted in three stages. First, we examined the bidirectional association between social autistic traits at age 8 years and emotion recognition task (ERT) responses at age 24 years (Study 1; N = 3,562); and between Diagnostic Analysis of Non-Verbal Accuracy (DANVA) emotion recognition responses at age 8 years and social autistic traits at age 10 years (Study 2; N = 9,071). Next, we used genetic analyses (Study 3) to examine the association between polygenic risk scores for ASD and outcomes for the ERT and DANVA. The genetic correlation between ASD and ERT responses at age 24 was also estimated. Analyses were conducted in the Avon Longitudinal Study of Parents and Children. RESULTS: Social autistic traits at age 8 years were negatively associated with later total correct responses on ERT in Study 1 (b = -0.18; 95% CI: -0.27 to -0.09). We also found evidence of an association in Study 2 (b = -0.04; 95% CI: -0.05 to -0.03). We found the opposite association, that is positive, between the ASD polygenic risk score and ERT (b = 0.40; 95% CI: 0.10 to 0.70); however, this association varied across different p-value thresholds and would not survive multiple testing, so should be interpreted with caution. We did not find evidence of a genetic correlation between ASD and ERT. CONCLUSION: We found an observational association between poorer emotion recognition and increased social autistic traits. Our genetic analyses may suggest a shared genetic aetiology between these or a potential causal pathway; however, future research would benefit from using better powered GWAS to examine this further. Our results may inform interventions targeting emotion recognition. En ligne : http://dx.doi.org/10.1111/jcpp.13395 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Examining the bidirectional association between emotion recognition and social autistic traits using observational and genetic analyses [Texte imprimé et/ou numérique] / Z. E. REED, Auteur ; L. MAHEDY, Auteur ; A. JACKSON, Auteur ; George DAVEY SMITH, Auteur ; I. PENTON-VOAK, Auteur ; A. S. ATTWOOD, Auteur ; M. R. MUNAFO, Auteur . - p.1330-1338. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-11 (November 2021) . - p.1330-1338 Mots-clés : Adult  Autism Spectrum Disorder/genetics  Autistic Disorder  Child  Emotions  Humans  Longitudinal Studies  Parents  Young Adult  Alspac  Autism spectrum disorder  emotion recognition  polygenic risk score  social autistic traits Index. décimale : PER Périodiques Résumé : BACKGROUND: There is mixed evidence for an association between autism spectrum disorder (ASD) and emotion recognition deficits. We sought to assess the bidirectionality of this association using phenotypic and genetic data in a large community sample. METHODS: Analyses were conducted in three stages. First, we examined the bidirectional association between social autistic traits at age 8 years and emotion recognition task (ERT) responses at age 24 years (Study 1; N = 3,562); and between Diagnostic Analysis of Non-Verbal Accuracy (DANVA) emotion recognition responses at age 8 years and social autistic traits at age 10 years (Study 2; N = 9,071). Next, we used genetic analyses (Study 3) to examine the association between polygenic risk scores for ASD and outcomes for the ERT and DANVA. The genetic correlation between ASD and ERT responses at age 24 was also estimated. Analyses were conducted in the Avon Longitudinal Study of Parents and Children. RESULTS: Social autistic traits at age 8 years were negatively associated with later total correct responses on ERT in Study 1 (b = -0.18; 95% CI: -0.27 to -0.09). We also found evidence of an association in Study 2 (b = -0.04; 95% CI: -0.05 to -0.03). We found the opposite association, that is positive, between the ASD polygenic risk score and ERT (b = 0.40; 95% CI: 0.10 to 0.70); however, this association varied across different p-value thresholds and would not survive multiple testing, so should be interpreted with caution. We did not find evidence of a genetic correlation between ASD and ERT. CONCLUSION: We found an observational association between poorer emotion recognition and increased social autistic traits. Our genetic analyses may suggest a shared genetic aetiology between these or a potential causal pathway; however, future research would benefit from using better powered GWAS to examine this further. Our results may inform interventions targeting emotion recognition. En ligne : http://dx.doi.org/10.1111/jcpp.13395 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Exposure to childhood adversity and deficits in emotion recognition: results from a large, population-based sample / E. C. DUNN in Journal of Child Psychology and Psychiatry, 59-8 (August 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-8 (August 2018) . - p.845-854 Titre : Exposure to childhood adversity and deficits in emotion recognition: results from a large, population-based sample Type de document : Texte imprimé et/ou numérique Auteurs : E. C. DUNN, Auteur ; Katherine M. CRAWFORD, Auteur ; T. W. SOARE, Auteur ; K. S. BUTTON, Auteur ; M. R. RAFFELD, Auteur ; Adac SMITH, Auteur ; I. S. PENTON-VOAK, Auteur ; M. R. MUNAFO, Auteur Article en page(s) : p.845-854 Langues : Anglais (eng) Mots-clés : Alspac  Sensitive periods  adversity  children  emotion recognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Emotion recognition skills are essential for social communication. Deficits in these skills have been implicated in mental disorders. Prior studies of clinical and high-risk samples have consistently shown that children exposed to adversity are more likely than their unexposed peers to have emotion recognition skills deficits. However, only one population-based study has examined this association. METHODS: We analyzed data from children participating in the Avon Longitudinal Study of Parents and Children, a prospective birth cohort (n = 6,506). We examined the association between eight adversities, assessed repeatedly from birth to age 8 (caregiver physical or emotional abuse; sexual or physical abuse; maternal psychopathology; one adult in the household; family instability; financial stress; parent legal problems; neighborhood disadvantage) and the ability to recognize facial displays of emotion measured using the faces subtest of the Diagnostic Assessment of Non-Verbal Accuracy (DANVA) at age 8.5 years. In addition to examining the role of exposure (vs. nonexposure) to each type of adversity, we also evaluated the role of the timing, duration, and recency of each adversity using a Least Angle Regression variable selection procedure. RESULTS: Over three-quarters of the sample experienced at least one adversity. We found no evidence to support an association between emotion recognition deficits and previous exposure to adversity, either in terms of total lifetime exposure, timing, duration, or recency, or when stratifying by sex. CONCLUSIONS: Results from the largest population-based sample suggest that even extreme forms of adversity are unrelated to emotion recognition deficits as measured by the DANVA, suggesting the possible immutability of emotion recognition in the general population. These findings emphasize the importance of population-based studies to generate generalizable results. En ligne : http://dx.doi.org/10.1111/jcpp.12881 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 [article] Exposure to childhood adversity and deficits in emotion recognition: results from a large, population-based sample [Texte imprimé et/ou numérique] / E. C. DUNN, Auteur ; Katherine M. CRAWFORD, Auteur ; T. W. SOARE, Auteur ; K. S. BUTTON, Auteur ; M. R. RAFFELD, Auteur ; Adac SMITH, Auteur ; I. S. PENTON-VOAK, Auteur ; M. R. MUNAFO, Auteur . - p.845-854. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-8 (August 2018) . - p.845-854 Mots-clés : Alspac  Sensitive periods  adversity  children  emotion recognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Emotion recognition skills are essential for social communication. Deficits in these skills have been implicated in mental disorders. Prior studies of clinical and high-risk samples have consistently shown that children exposed to adversity are more likely than their unexposed peers to have emotion recognition skills deficits. However, only one population-based study has examined this association. METHODS: We analyzed data from children participating in the Avon Longitudinal Study of Parents and Children, a prospective birth cohort (n = 6,506). We examined the association between eight adversities, assessed repeatedly from birth to age 8 (caregiver physical or emotional abuse; sexual or physical abuse; maternal psychopathology; one adult in the household; family instability; financial stress; parent legal problems; neighborhood disadvantage) and the ability to recognize facial displays of emotion measured using the faces subtest of the Diagnostic Assessment of Non-Verbal Accuracy (DANVA) at age 8.5 years. In addition to examining the role of exposure (vs. nonexposure) to each type of adversity, we also evaluated the role of the timing, duration, and recency of each adversity using a Least Angle Regression variable selection procedure. RESULTS: Over three-quarters of the sample experienced at least one adversity. We found no evidence to support an association between emotion recognition deficits and previous exposure to adversity, either in terms of total lifetime exposure, timing, duration, or recency, or when stratifying by sex. CONCLUSIONS: Results from the largest population-based sample suggest that even extreme forms of adversity are unrelated to emotion recognition deficits as measured by the DANVA, suggesting the possible immutability of emotion recognition in the general population. These findings emphasize the importance of population-based studies to generate generalizable results. En ligne : http://dx.doi.org/10.1111/jcpp.12881 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

Impaired Recognition of Basic Emotions from Facial Expressions in Young People with Autism Spectrum Disorder: Assessing the Importance of Expression Intensity / S. GRIFFITHS in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2768-2778 Titre : Impaired Recognition of Basic Emotions from Facial Expressions in Young People with Autism Spectrum Disorder: Assessing the Importance of Expression Intensity Type de document : Texte imprimé et/ou numérique Auteurs : S. GRIFFITHS, Auteur ; C. JARROLD, Auteur ; I. S. PENTON-VOAK, Auteur ; A. T. WOODS, Auteur ; A. L. SKINNER, Auteur ; M. R. MUNAFO, Auteur Article en page(s) : p.2768-2778 Langues : Anglais (eng) Mots-clés : Bias  Emotion recognition  Facial expression  Intensity  Online testing  Perception Index. décimale : PER Périodiques Résumé : It has been proposed that impairments in emotion recognition in ASD are greater for more subtle expressions of emotion. We measured recognition of 6 basic facial expressions at 8 intensity levels in young people (6-16 years) with ASD (N = 63) and controls (N = 64) via an Internet platform. Participants with ASD were less accurate than controls at labelling expressions across intensity levels, although differences at very low levels were not detected due to floor effects. Recognition accuracy did not correlate with parent-reported social functioning in either group. These findings provide further evidence for an impairment in recognition of basic emotion in ASD and do not support the idea that this impairment is limited solely to low intensity expressions. En ligne : http://dx.doi.org/10.1007/s10803-017-3091-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=401 [article] Impaired Recognition of Basic Emotions from Facial Expressions in Young People with Autism Spectrum Disorder: Assessing the Importance of Expression Intensity [Texte imprimé et/ou numérique] / S. GRIFFITHS, Auteur ; C. JARROLD, Auteur ; I. S. PENTON-VOAK, Auteur ; A. T. WOODS, Auteur ; A. L. SKINNER, Auteur ; M. R. MUNAFO, Auteur . - p.2768-2778. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2768-2778 Mots-clés : Bias  Emotion recognition  Facial expression  Intensity  Online testing  Perception Index. décimale : PER Périodiques Résumé : It has been proposed that impairments in emotion recognition in ASD are greater for more subtle expressions of emotion. We measured recognition of 6 basic facial expressions at 8 intensity levels in young people (6-16 years) with ASD (N = 63) and controls (N = 64) via an Internet platform. Participants with ASD were less accurate than controls at labelling expressions across intensity levels, although differences at very low levels were not detected due to floor effects. Recognition accuracy did not correlate with parent-reported social functioning in either group. These findings provide further evidence for an impairment in recognition of basic emotion in ASD and do not support the idea that this impairment is limited solely to low intensity expressions. En ligne : http://dx.doi.org/10.1007/s10803-017-3091-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=401

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