Developing a Diagnostic Algorithm for the Music-Based Scale for Autism Diagnostics (MUSAD) Assessing Adults with Intellectual Disability / T. BERGMANN in Journal of Autism and Developmental Disorders, 49-9 (September 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-9 (September 2019) . - p.3732-3752 Titre : Developing a Diagnostic Algorithm for the Music-Based Scale for Autism Diagnostics (MUSAD) Assessing Adults with Intellectual Disability Type de document : Texte imprimé et/ou numérique Auteurs : T. BERGMANN, Auteur ; M. HEINRICH, Auteur ; M. ZIEGLER, Auteur ; I. DZIOBEK, Auteur ; A. DIEFENBACHER, Auteur ; T. SAPPOK, Auteur Article en page(s) : p.3732-3752 Langues : Anglais (eng) Mots-clés : Adults  Autism spectrum disorder  Diagnostic  Intellectual disability  Music Index. décimale : PER Périodiques Résumé : Initial studies have presented the Music-based Scale for Autism Diagnostics (MUSAD) as a promising DSM-5-based observational tool to identify autism spectrum disorder (ASD) in adults with intellectual disability (ID). The current study is the first to address its clinical utility in a new sample of 124 adults with ID (60.5% diagnosed with ASD). The derived diagnostic algorithm differentiated well between individuals with and without ASD (sensitivity 79%, specificity 74%, area under the curve = 0.81). Inter-rater reliability, assessed by the scorings of four independent experts in 22 consensus cases, was excellent (ICC = 0.92). Substantial correlations with scores from other ASD-specific measures indicated convergent validity. The MUSAD yields accurate and reliable scores, supporting comprehensive ASD diagnostics in adults with ID. En ligne : http://dx.doi.org/10.1007/s10803-019-04069-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405 [article] Developing a Diagnostic Algorithm for the Music-Based Scale for Autism Diagnostics (MUSAD) Assessing Adults with Intellectual Disability [Texte imprimé et/ou numérique] / T. BERGMANN, Auteur ; M. HEINRICH, Auteur ; M. ZIEGLER, Auteur ; I. DZIOBEK, Auteur ; A. DIEFENBACHER, Auteur ; T. SAPPOK, Auteur . - p.3732-3752. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-9 (September 2019) . - p.3732-3752 Mots-clés : Adults  Autism spectrum disorder  Diagnostic  Intellectual disability  Music Index. décimale : PER Périodiques Résumé : Initial studies have presented the Music-based Scale for Autism Diagnostics (MUSAD) as a promising DSM-5-based observational tool to identify autism spectrum disorder (ASD) in adults with intellectual disability (ID). The current study is the first to address its clinical utility in a new sample of 124 adults with ID (60.5% diagnosed with ASD). The derived diagnostic algorithm differentiated well between individuals with and without ASD (sensitivity 79%, specificity 74%, area under the curve = 0.81). Inter-rater reliability, assessed by the scorings of four independent experts in 22 consensus cases, was excellent (ICC = 0.92). Substantial correlations with scores from other ASD-specific measures indicated convergent validity. The MUSAD yields accurate and reliable scores, supporting comprehensive ASD diagnostics in adults with ID. En ligne : http://dx.doi.org/10.1007/s10803-019-04069-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405

Imitation and recognition of facial emotions in autism: a computer vision approach / H. DRIMALLA in Molecular Autism, 12 (2021)  

Public ISBD [article]  inMolecular Autism > 12 (2021) . - 27 p. Titre : Imitation and recognition of facial emotions in autism: a computer vision approach Type de document : Texte imprimé et/ou numérique Auteurs : H. DRIMALLA, Auteur ; Irina BASKOW, Auteur ; B. BEHNIA, Auteur ; S. ROEPKE, Auteur ; I. DZIOBEK, Auteur Article en page(s) : 27 p. Langues : Anglais (eng) Mots-clés : Adult  Autistic Disorder/psychology  Emotions  Facial Expression  Female  Humans  Imitative Behavior  Male  Middle Aged  Recognition, Psychology  Signal Processing, Computer-Assisted  Young Adult  Autism  Automated analysis  Emotion recognition  Imitation Index. décimale : PER Périodiques Résumé : BACKGROUND: Imitation of facial expressions plays an important role in social functioning. However, little is known about the quality of facial imitation in individuals with autism and its relationship with defining difficulties in emotion recognition. METHODS: We investigated imitation and recognition of facial expressions in 37 individuals with autism spectrum conditions and 43 neurotypical controls. Using a novel computer-based face analysis, we measured instructed imitation of facial emotional expressions and related it to emotion recognition abilities. RESULTS: Individuals with autism imitated facial expressions if instructed to do so, but their imitation was both slower and less precise than that of neurotypical individuals. In both groups, a more precise imitation scaled positively with participants' accuracy of emotion recognition. LIMITATIONS: Given the study's focus on adults with autism without intellectual impairment, it is unclear whether the results generalize to children with autism or individuals with intellectual disability. Further, the new automated facial analysis, despite being less intrusive than electromyography, might be less sensitive. CONCLUSIONS: Group differences in emotion recognition, imitation and their interrelationships highlight potential for treatment of social interaction problems in individuals with autism. En ligne : http://dx.doi.org/10.1186/s13229-021-00430-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459 [article] Imitation and recognition of facial emotions in autism: a computer vision approach [Texte imprimé et/ou numérique] / H. DRIMALLA, Auteur ; Irina BASKOW, Auteur ; B. BEHNIA, Auteur ; S. ROEPKE, Auteur ; I. DZIOBEK, Auteur . - 27 p. Langues : Anglais (eng) in Molecular Autism > 12 (2021) . - 27 p. Mots-clés : Adult  Autistic Disorder/psychology  Emotions  Facial Expression  Female  Humans  Imitative Behavior  Male  Middle Aged  Recognition, Psychology  Signal Processing, Computer-Assisted  Young Adult  Autism  Automated analysis  Emotion recognition  Imitation Index. décimale : PER Périodiques Résumé : BACKGROUND: Imitation of facial expressions plays an important role in social functioning. However, little is known about the quality of facial imitation in individuals with autism and its relationship with defining difficulties in emotion recognition. METHODS: We investigated imitation and recognition of facial expressions in 37 individuals with autism spectrum conditions and 43 neurotypical controls. Using a novel computer-based face analysis, we measured instructed imitation of facial emotional expressions and related it to emotion recognition abilities. RESULTS: Individuals with autism imitated facial expressions if instructed to do so, but their imitation was both slower and less precise than that of neurotypical individuals. In both groups, a more precise imitation scaled positively with participants' accuracy of emotion recognition. LIMITATIONS: Given the study's focus on adults with autism without intellectual impairment, it is unclear whether the results generalize to children with autism or individuals with intellectual disability. Further, the new automated facial analysis, despite being less intrusive than electromyography, might be less sensitive. CONCLUSIONS: Group differences in emotion recognition, imitation and their interrelationships highlight potential for treatment of social interaction problems in individuals with autism. En ligne : http://dx.doi.org/10.1186/s13229-021-00430-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459

Outpatient Psychotherapy for Adults with High-Functioning Autism Spectrum Condition: Utilization, Treatment Satisfaction, and Preferred Modifications / S. LIPINSKI in Journal of Autism and Developmental Disorders, 49-3 (March 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-3 (March 2019) . - p.1154-1168 Titre : Outpatient Psychotherapy for Adults with High-Functioning Autism Spectrum Condition: Utilization, Treatment Satisfaction, and Preferred Modifications Type de document : Texte imprimé et/ou numérique Auteurs : S. LIPINSKI, Auteur ; E. S. BLANKE, Auteur ; U. SUENKEL, Auteur ; I. DZIOBEK, Auteur Article en page(s) : p.1154-1168 Langues : Anglais (eng) Mots-clés : Adult psychotherapy  Asperger syndrome  Autism  Autism spectrum disorder  Mental health  Participatory research Index. décimale : PER Périodiques Résumé : Many adults with autism spectrum condition (ASC) desire outpatient psychotherapy (PT). This study compared reasons for seeking PT, experiences with PT, and modifications preferred with respect to PT of individuals with ASC to non-autistic individuals with depression (MDD). Furthermore, factors predictive for treatment satisfaction were identified in individuals with ASC. A total of 262 adults with ASC without intellectual impairment and 304 non-autistic controls with MDD were surveyed. In this pilot study both groups predominantly sought treatment for depressiveness. A low level of expertise with autism was the main reason for being declined by therapists and a contributing factor to the overall treatment dissatisfaction of patients with ASC. ASC patients desire adjustments such as written communication, and clearly structured sessions. En ligne : http://dx.doi.org/10.1007/s10803-018-3797-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 [article] Outpatient Psychotherapy for Adults with High-Functioning Autism Spectrum Condition: Utilization, Treatment Satisfaction, and Preferred Modifications [Texte imprimé et/ou numérique] / S. LIPINSKI, Auteur ; E. S. BLANKE, Auteur ; U. SUENKEL, Auteur ; I. DZIOBEK, Auteur . - p.1154-1168. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-3 (March 2019) . - p.1154-1168 Mots-clés : Adult psychotherapy  Asperger syndrome  Autism  Autism spectrum disorder  Mental health  Participatory research Index. décimale : PER Périodiques Résumé : Many adults with autism spectrum condition (ASC) desire outpatient psychotherapy (PT). This study compared reasons for seeking PT, experiences with PT, and modifications preferred with respect to PT of individuals with ASC to non-autistic individuals with depression (MDD). Furthermore, factors predictive for treatment satisfaction were identified in individuals with ASC. A total of 262 adults with ASC without intellectual impairment and 304 non-autistic controls with MDD were surveyed. In this pilot study both groups predominantly sought treatment for depressiveness. A low level of expertise with autism was the main reason for being declined by therapists and a contributing factor to the overall treatment dissatisfaction of patients with ASC. ASC patients desire adjustments such as written communication, and clearly structured sessions. En ligne : http://dx.doi.org/10.1007/s10803-018-3797-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386

Pupil Dilation Progression Modulates Aberrant Social Cognition in Autism Spectrum Disorder / Nico BAST in Autism Research, 12-11 (November 2019)  

Public ISBD [article]  inAutism Research > 12-11 (November 2019) . - p.1680-1692 Titre : Pupil Dilation Progression Modulates Aberrant Social Cognition in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Nico BAST, Auteur ; Tobias BANASCHEWSKI, Auteur ; I. DZIOBEK, Auteur ; Daniel BRANDEIS, Auteur ; L. POUSTKA, Auteur ; C. M. FREITAG, Auteur Article en page(s) : p.1680-1692 Langues : Anglais (eng) Mots-clés : attention modulation  biomarker  eye tracking  pupillary reactivity  sensory processing Index. décimale : PER Périodiques Résumé : Progression of pupil dilation (PD) in response to visual stimuli may indicate distinct internal processes. No study has been performed on PD progression during a social cognition task. Here, we describe PD progression during the Movie for the Assessment of Social Cognition (MASC) test in n = 23 adolescents with Autism Spectrum Disorder (ASD) and n = 24 age, IQ and sex-matched neurotypical controls (NTC). The MASC consists of 43 video sequences depicting human social interactions, each followed by a multiple-choice question concerning characters' mental states. PD progression data were extracted by eye tracking and controlled for fixation behavior. Segmenting PD progression during video sequences by principal component analysis, three sequential PD components were unveiled. In ASD compared with NTC, a distinct PD progression was observed with increased constriction amplitude, increased dilation latency, and increased dilation amplitude that correlated with PD progression components. These components predicted social cognition performance. The first and second PD components correlated positively with MASC behavioral performance in ASD but negatively in NTC. These PD components may be interpreted as indicators of sensory-perceptual processing and attention function. In ASD, aberrant sensory-perceptual processing and attention function could contribute to attenuated social cognition performance. This needs to be tested by additional studies combining the respective cognitive tests and the outlined PD progression analysis. Phasic activity of the locus coeruleus-norepinephrine system is discussed as putatively shared underlying mechanism. Autism Res2019. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: In adolescents with autism, we found an altered pupil dilation during watching scenes of human interactions. Early pupil dilation correlated positively with the number of correct answers to questions about the shown human interactions. Our findings suggest that aberrant sensory processing and attention function may contribute to altered social cognition in autism. En ligne : http://dx.doi.org/10.1002/aur.2178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412 [article] Pupil Dilation Progression Modulates Aberrant Social Cognition in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Nico BAST, Auteur ; Tobias BANASCHEWSKI, Auteur ; I. DZIOBEK, Auteur ; Daniel BRANDEIS, Auteur ; L. POUSTKA, Auteur ; C. M. FREITAG, Auteur . - p.1680-1692. Langues : Anglais (eng) in Autism Research > 12-11 (November 2019) . - p.1680-1692 Mots-clés : attention modulation  biomarker  eye tracking  pupillary reactivity  sensory processing Index. décimale : PER Périodiques Résumé : Progression of pupil dilation (PD) in response to visual stimuli may indicate distinct internal processes. No study has been performed on PD progression during a social cognition task. Here, we describe PD progression during the Movie for the Assessment of Social Cognition (MASC) test in n = 23 adolescents with Autism Spectrum Disorder (ASD) and n = 24 age, IQ and sex-matched neurotypical controls (NTC). The MASC consists of 43 video sequences depicting human social interactions, each followed by a multiple-choice question concerning characters' mental states. PD progression data were extracted by eye tracking and controlled for fixation behavior. Segmenting PD progression during video sequences by principal component analysis, three sequential PD components were unveiled. In ASD compared with NTC, a distinct PD progression was observed with increased constriction amplitude, increased dilation latency, and increased dilation amplitude that correlated with PD progression components. These components predicted social cognition performance. The first and second PD components correlated positively with MASC behavioral performance in ASD but negatively in NTC. These PD components may be interpreted as indicators of sensory-perceptual processing and attention function. In ASD, aberrant sensory-perceptual processing and attention function could contribute to attenuated social cognition performance. This needs to be tested by additional studies combining the respective cognitive tests and the outlined PD progression analysis. Phasic activity of the locus coeruleus-norepinephrine system is discussed as putatively shared underlying mechanism. Autism Res2019. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: In adolescents with autism, we found an altered pupil dilation during watching scenes of human interactions. Early pupil dilation correlated positively with the number of correct answers to questions about the shown human interactions. Our findings suggest that aberrant sensory processing and attention function may contribute to altered social cognition in autism. En ligne : http://dx.doi.org/10.1002/aur.2178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412

Visual and Proprioceptive Influences on Tactile Spatial Processing in Adults with Autism Spectrum Disorders / M. HENSE in Autism Research, 12-12 (December)  

Public ISBD [article]  inAutism Research > 12-12 (December) . - p.1745-1757 Titre : Visual and Proprioceptive Influences on Tactile Spatial Processing in Adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : M. HENSE, Auteur ; S. BADDE, Auteur ; S. KOHNE, Auteur ; I. DZIOBEK, Auteur ; B. RODER, Auteur Année de publication : 2019 Article en page(s) : p.1745-1757 Langues : Anglais (eng) Mots-clés : adult  autism spectrum disorder  multisensory integration  posture  spatial processing  touch Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASDs) often exhibit altered representations of the external world. Consistently, when localizing touch, children with ASDs were less influenced than their peers by changes of the stimulated limb's location in external space [Wada et al., Scientific Reports 2015, 4(1), 5985]. However, given the protracted development of an external-spatial dominance in tactile processing in typically developing children, this difference might reflect a developmental delay rather than a set suppression of external space in ASDs. Here, adults with ASDs and matched control-participants completed (a) the tactile temporal order judgment (TOJ) task previously used to test external-spatial representation of touch in children with ASDs and (b) a tactile-visual cross-modal congruency (CC) task which assesses benefits of task-irrelevant visual stimuli on tactile localization in external space. In both experiments, participants localized tactile stimuli to the fingers of each hand, while holding their hands either crossed or uncrossed. Performance differences between hand postures reflect the influence of external-spatial codes. In both groups, tactile TOJ-performance markedly decreased when participants crossed their hands and CC-effects were especially large if the visual stimulus was presented at the same side of external space as the task-relevant touch. The absence of group differences was statistically confirmed using Bayesian statistical modeling: adults with ASDs weighted external-spatial codes comparable to typically developed adults during tactile and visual-tactile spatio-temporal tasks. Thus, atypicalities in the spatial coding of touch for children with ASDs appear to reflect a developmental delay rather than a stable characteristic of ASD. Autism Res 2019, 12: 1745-1757. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: A touched limb's location can be described twofold, with respect to the body (right hand) or the external world (right side). Children and adolescents with autism spectrum disorder (ASD) reportedly rely less than their peers on the external world. Here, adults with and without ASDs completed two tactile localization tasks. Both groups relied to the same degree on external world locations. This opens the possibility that the tendency to relate touch to the external world is typical in individuals with ASDs but emerges with a delay. En ligne : http://dx.doi.org/10.1002/aur.2202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 [article] Visual and Proprioceptive Influences on Tactile Spatial Processing in Adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / M. HENSE, Auteur ; S. BADDE, Auteur ; S. KOHNE, Auteur ; I. DZIOBEK, Auteur ; B. RODER, Auteur . - 2019 . - p.1745-1757. Langues : Anglais (eng) in Autism Research > 12-12 (December) . - p.1745-1757 Mots-clés : adult  autism spectrum disorder  multisensory integration  posture  spatial processing  touch Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASDs) often exhibit altered representations of the external world. Consistently, when localizing touch, children with ASDs were less influenced than their peers by changes of the stimulated limb's location in external space [Wada et al., Scientific Reports 2015, 4(1), 5985]. However, given the protracted development of an external-spatial dominance in tactile processing in typically developing children, this difference might reflect a developmental delay rather than a set suppression of external space in ASDs. Here, adults with ASDs and matched control-participants completed (a) the tactile temporal order judgment (TOJ) task previously used to test external-spatial representation of touch in children with ASDs and (b) a tactile-visual cross-modal congruency (CC) task which assesses benefits of task-irrelevant visual stimuli on tactile localization in external space. In both experiments, participants localized tactile stimuli to the fingers of each hand, while holding their hands either crossed or uncrossed. Performance differences between hand postures reflect the influence of external-spatial codes. In both groups, tactile TOJ-performance markedly decreased when participants crossed their hands and CC-effects were especially large if the visual stimulus was presented at the same side of external space as the task-relevant touch. The absence of group differences was statistically confirmed using Bayesian statistical modeling: adults with ASDs weighted external-spatial codes comparable to typically developed adults during tactile and visual-tactile spatio-temporal tasks. Thus, atypicalities in the spatial coding of touch for children with ASDs appear to reflect a developmental delay rather than a stable characteristic of ASD. Autism Res 2019, 12: 1745-1757. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: A touched limb's location can be described twofold, with respect to the body (right hand) or the external world (right side). Children and adolescents with autism spectrum disorder (ASD) reportedly rely less than their peers on the external world. Here, adults with and without ASDs completed two tactile localization tasks. Both groups relied to the same degree on external world locations. This opens the possibility that the tendency to relate touch to the external world is typical in individuals with ASDs but emerges with a delay. En ligne : http://dx.doi.org/10.1002/aur.2202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413

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