Head Growth Trajectories During the First Year of Life and Risk of Autism Spectrum Disorder / Rewaa BALAUM in Autism Research, 19-2 (February 2026)  

Public ISBD [article]  inAutism Research > 19-2 (February 2026) . - e70172 Titre : Head Growth Trajectories During the First Year of Life and Risk of Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Rewaa BALAUM, Auteur ; Leena ELBEDOUR, Auteur ; Einav ALHOZYEL, Auteur ; Gal MEIRI, Auteur ; Dikla ZIGDON, Auteur ; Analya MICHAELOVSKI, Auteur ; Orly KERUB, Auteur ; Idan MENASHE, Auteur Article en page(s) : e70172 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  growth trajectories  head circumference  height  macrocephaly  microcephaly Index. décimale : PER Périodiques Résumé : ABSTRACT Atypical infant head circumference (HC)?including increased rates of macrocephaly and microcephaly?has been linked to autism spectrum disorder (ASD). However, specific head growth trajectories associated with ASD remain poorly defined. This retrospective case?control study aimed to delineate these trajectories and examine their relationship to height. The study sample included 262 children diagnosed with ASD and 560 matched controls. Growth measures at 1, 2, 4, 6, 9, and 12?months of age were obtained from health clinics in southern Israel. The sample was classified into seven clusters based on HC patterns across these six time points, and associations with ASD were estimated using conditional logistic regression. Results demonstrated significant correlations between HC and height throughout the study period (Pearson correlation r?=?0.44?0.55, p? En ligne : https://doi.org/10.1002/aur.70172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 [article] Head Growth Trajectories During the First Year of Life and Risk of Autism Spectrum Disorder [texte imprimé] / Rewaa BALAUM, Auteur ; Leena ELBEDOUR, Auteur ; Einav ALHOZYEL, Auteur ; Gal MEIRI, Auteur ; Dikla ZIGDON, Auteur ; Analya MICHAELOVSKI, Auteur ; Orly KERUB, Auteur ; Idan MENASHE, Auteur . - e70172. Langues : Anglais (eng) in Autism Research > 19-2 (February 2026) . - e70172 Mots-clés : autism spectrum disorder  growth trajectories  head circumference  height  macrocephaly  microcephaly Index. décimale : PER Périodiques Résumé : ABSTRACT Atypical infant head circumference (HC)?including increased rates of macrocephaly and microcephaly?has been linked to autism spectrum disorder (ASD). However, specific head growth trajectories associated with ASD remain poorly defined. This retrospective case?control study aimed to delineate these trajectories and examine their relationship to height. The study sample included 262 children diagnosed with ASD and 560 matched controls. Growth measures at 1, 2, 4, 6, 9, and 12?months of age were obtained from health clinics in southern Israel. The sample was classified into seven clusters based on HC patterns across these six time points, and associations with ASD were estimated using conditional logistic regression. Results demonstrated significant correlations between HC and height throughout the study period (Pearson correlation r?=?0.44?0.55, p? En ligne : https://doi.org/10.1002/aur.70172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582

Sleep disturbances are associated with greater healthcare utilization in children with autism spectrum disorder / Shirley SOLOMON in Journal of Neurodevelopmental Disorders, 16 (2024)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 16 (2024) Titre : Sleep disturbances are associated with greater healthcare utilization in children with autism spectrum disorder Type de document : texte imprimé Auteurs : Shirley SOLOMON, Auteur ; Leena ELBEDOUR, Auteur ; Gal MEIRI, Auteur ; Analya MICHAELOVSKI, Auteur ; Yair SADAKA, Auteur ; Michal ILAN, Auteur ; Michal FAROY, Auteur ; Ilan DINSTEIN, Auteur ; Idan MENASHE, Auteur Langues : Anglais (eng) Mots-clés : Humans  Autism Spectrum Disorder/complications/epidemiology/therapy  Male  Female  Sleep Wake Disorders/epidemiology/etiology/therapy  Child  Cross-Sectional Studies  Retrospective Studies  Patient Acceptance of Health Care/statistics & numerical data  Child, Preschool  Comorbidity  Adolescent  Hospitalization/statistics & numerical data  Autism  Autism spectrum disorder (ASD)  Co-occurring conditions  Healthcare utilization  Medication use  Melatonin  Sleep  Sleep disturbances Index. décimale : PER Périodiques Résumé : BACKGROUND: Sleep disturbances are frequently reported in children with autism spectrum disorder (ASD) and are associated with the severity of co-occurring symptoms. This study's aim was to examine the extent of healthcare utilization and clinical outcomes associated with sleep disturbances in children with ASD. STUDY DESIGN: A retrospective, cross-sectional study of 541 children with ASD from the Azrieli National Center for Autism and Neurodevelopment Research (ANCAN) whose parents completed the Children's Sleep Habits Questionnaire (CSHQ). Children with a total CSHQ score ≥ 48 were defined as having sleep disturbances. Sociodemographic characteristics, ASD diagnostic measures, chronic co-occurring conditions, medication usage, hospitalizations, visits to the emergency room (ER), and visits to specialists were compared in ASD children with and without sleep disturbances. Multivariate logistic regression models were then used to assess the independent association of sleep disturbances with clinical characteristics and healthcare utilization. RESULTS: Of the 541 children with ASD, 257 (47.5%) had sleep disturbances. Children with sleep disturbances exhibited higher rates of multiple (≥ 3) co-occurring conditions (19.1% vs. 12.7%; p = 0.0414) and prescribed medications (45.5% vs. 32.7%; p = 0.0031) than other children. Finally, ASD children with sleep disturbances were 1.72 and 2.71 times more likely to visit the ER and be hospitalized than their counterparts (aOR = 1.72; 99%CI = 1.01-2.95; and aOR = 2.71; 99%CI = 1.10-6.67, respectively). CONCLUSIONS: Our findings suggest that sleep disturbances are associated with greater healthcare utilization among children with ASD. Further studies could examine whether treating sleep disturbances in children with ASD yields additional clinical benefits beyond improvements in sleep. En ligne : https://dx.doi.org/10.1186/s11689-024-09550-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575 [article] Sleep disturbances are associated with greater healthcare utilization in children with autism spectrum disorder [texte imprimé] / Shirley SOLOMON, Auteur ; Leena ELBEDOUR, Auteur ; Gal MEIRI, Auteur ; Analya MICHAELOVSKI, Auteur ; Yair SADAKA, Auteur ; Michal ILAN, Auteur ; Michal FAROY, Auteur ; Ilan DINSTEIN, Auteur ; Idan MENASHE, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 16 (2024) Mots-clés : Humans  Autism Spectrum Disorder/complications/epidemiology/therapy  Male  Female  Sleep Wake Disorders/epidemiology/etiology/therapy  Child  Cross-Sectional Studies  Retrospective Studies  Patient Acceptance of Health Care/statistics & numerical data  Child, Preschool  Comorbidity  Adolescent  Hospitalization/statistics & numerical data  Autism  Autism spectrum disorder (ASD)  Co-occurring conditions  Healthcare utilization  Medication use  Melatonin  Sleep  Sleep disturbances Index. décimale : PER Périodiques Résumé : BACKGROUND: Sleep disturbances are frequently reported in children with autism spectrum disorder (ASD) and are associated with the severity of co-occurring symptoms. This study's aim was to examine the extent of healthcare utilization and clinical outcomes associated with sleep disturbances in children with ASD. STUDY DESIGN: A retrospective, cross-sectional study of 541 children with ASD from the Azrieli National Center for Autism and Neurodevelopment Research (ANCAN) whose parents completed the Children's Sleep Habits Questionnaire (CSHQ). Children with a total CSHQ score ≥ 48 were defined as having sleep disturbances. Sociodemographic characteristics, ASD diagnostic measures, chronic co-occurring conditions, medication usage, hospitalizations, visits to the emergency room (ER), and visits to specialists were compared in ASD children with and without sleep disturbances. Multivariate logistic regression models were then used to assess the independent association of sleep disturbances with clinical characteristics and healthcare utilization. RESULTS: Of the 541 children with ASD, 257 (47.5%) had sleep disturbances. Children with sleep disturbances exhibited higher rates of multiple (≥ 3) co-occurring conditions (19.1% vs. 12.7%; p = 0.0414) and prescribed medications (45.5% vs. 32.7%; p = 0.0031) than other children. Finally, ASD children with sleep disturbances were 1.72 and 2.71 times more likely to visit the ER and be hospitalized than their counterparts (aOR = 1.72; 99%CI = 1.01-2.95; and aOR = 2.71; 99%CI = 1.10-6.67, respectively). CONCLUSIONS: Our findings suggest that sleep disturbances are associated with greater healthcare utilization among children with ASD. Further studies could examine whether treating sleep disturbances in children with ASD yields additional clinical benefits beyond improvements in sleep. En ligne : https://dx.doi.org/10.1186/s11689-024-09550-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575

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