Associations among maternal lifetime trauma, psychological symptoms in pregnancy, and infant stress reactivity and regulation / Carter R. PETTY ; Caroline HOWELL ; Juliana MENDONCA ; Abigail BOSSE ; Deborah P. WABER ; Rosalind J. WRIGHT ; Michelle BOSQUET ENLOW in Development and Psychopathology, 35-4 (October 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-4 (October 2023) . - p.1714-1731 Titre : Associations among maternal lifetime trauma, psychological symptoms in pregnancy, and infant stress reactivity and regulation Type de document : Texte imprimé et/ou numérique Auteurs : Carter R. PETTY, Auteur ; Caroline HOWELL, Auteur ; Juliana MENDONCA, Auteur ; Abigail BOSSE, Auteur ; Deborah P. WABER, Auteur ; Rosalind J. WRIGHT, Auteur ; Michelle BOSQUET ENLOW, Auteur Article en page(s) : p.1714-1731 Langues : Anglais (eng) Mots-clés : anxiety  infant  intergenerational trauma  pregnancy  regulation Index. décimale : PER Périodiques Résumé : Maternal trauma has intergenerational implications, including worse birth outcomes, altered brain morphology, and poorer mental health. Research investigating intergenerational effects of maternal trauma on infant stress reactivity and regulation is limited. Maternal mental health during pregnancy may be a contributor: psychopathology is a sequela of trauma exposure and predictor of altered self-regulatory capacity in offspring of affected mothers. We assessed associations among maternal lifetime trauma and infant stress responsivity, mediated by psychological symptoms in pregnancy. Mothers reported lifetime trauma history and anxiety, depressive, and posttraumatic stress symptoms during pregnancy. At infant age 6 months, stress reactivity and regulation were assessed via maternal behavior ratings (Infant Behavior Questionnaire-Revised, IBQ-R) and behavioral (negative mood) and physiological (respiratory sinus arrhythmia, RSA) markers during a laboratory stressor (Still-Face Paradigm). Maternal trauma was directly associated with lower infant physiological regulation and indirectly associated with lower levels of both infant behavioral and physiological regulation via higher maternal anxiety during pregnancy. Maternal trauma was also indirectly associated with higher infant reactivity via higher maternal anxiety during pregnancy. Post hoc analyses indicated differential contributions of maternal prenatal versus postnatal anxiety to infant outcomes. Findings highlight potential contributory mechanisms toward maladaptive child stress response, which has been associated with poor behavioral, cognitive, and academic outcomes. En ligne : https://dx.doi.org/10.1017/S0954579422000402 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515 [article] Associations among maternal lifetime trauma, psychological symptoms in pregnancy, and infant stress reactivity and regulation [Texte imprimé et/ou numérique] / Carter R. PETTY, Auteur ; Caroline HOWELL, Auteur ; Juliana MENDONCA, Auteur ; Abigail BOSSE, Auteur ; Deborah P. WABER, Auteur ; Rosalind J. WRIGHT, Auteur ; Michelle BOSQUET ENLOW, Auteur . - p.1714-1731. Langues : Anglais (eng) in Development and Psychopathology > 35-4 (October 2023) . - p.1714-1731 Mots-clés : anxiety  infant  intergenerational trauma  pregnancy  regulation Index. décimale : PER Périodiques Résumé : Maternal trauma has intergenerational implications, including worse birth outcomes, altered brain morphology, and poorer mental health. Research investigating intergenerational effects of maternal trauma on infant stress reactivity and regulation is limited. Maternal mental health during pregnancy may be a contributor: psychopathology is a sequela of trauma exposure and predictor of altered self-regulatory capacity in offspring of affected mothers. We assessed associations among maternal lifetime trauma and infant stress responsivity, mediated by psychological symptoms in pregnancy. Mothers reported lifetime trauma history and anxiety, depressive, and posttraumatic stress symptoms during pregnancy. At infant age 6 months, stress reactivity and regulation were assessed via maternal behavior ratings (Infant Behavior Questionnaire-Revised, IBQ-R) and behavioral (negative mood) and physiological (respiratory sinus arrhythmia, RSA) markers during a laboratory stressor (Still-Face Paradigm). Maternal trauma was directly associated with lower infant physiological regulation and indirectly associated with lower levels of both infant behavioral and physiological regulation via higher maternal anxiety during pregnancy. Maternal trauma was also indirectly associated with higher infant reactivity via higher maternal anxiety during pregnancy. Post hoc analyses indicated differential contributions of maternal prenatal versus postnatal anxiety to infant outcomes. Findings highlight potential contributory mechanisms toward maladaptive child stress response, which has been associated with poor behavioral, cognitive, and academic outcomes. En ligne : https://dx.doi.org/10.1017/S0954579422000402 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=515

Familial risk analysis of the association between attention-deficit/hyperactivity disorder and psychoactive substance use disorder in female adolescents: a controlled study / Joseph BIEDERMAN in Journal of Child Psychology and Psychiatry, 50-3 (March 2009)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 50-3 (March 2009) . - p.352-358 Titre : Familial risk analysis of the association between attention-deficit/hyperactivity disorder and psychoactive substance use disorder in female adolescents: a controlled study Type de document : Texte imprimé et/ou numérique Auteurs : Joseph BIEDERMAN, Auteur ; Michael C. MONUTEAUX, Auteur ; Stephen V. FARAONE, Auteur ; Carter R. PETTY, Auteur ; Eric MICK, Auteur ; Allison CLARKE, Auteur ; Kristina TEN HAAGEN, Auteur Année de publication : 2009 Article en page(s) : p.352-358 Langues : Anglais (eng) Mots-clés : ADHD substance-use female family-risk Index. décimale : PER Périodiques Résumé : Background: A robust and bi-directional comorbidity between attention-deficit/hyperactivity disorder (ADHD) and psychoactive substance use disorder (PSUD, alcohol or drug abuse, or dependence) has been consistently reported in the literature. However, this literature has been based almost exclusively on male only samples and, therefore, the findings may not generalize to females. Methods: First-degree relatives from a large sample of pediatrically and psychiatrically referred girls with (123 probands, 403 relatives) and without ADHD (112 probands, 359 relatives) were comprehensively assessed by blind raters with structured diagnostic interviews. Familial risk analysis examined the risks in first-degree relatives for ADHD and PSUD (alcohol or drug abuse or dependence) after stratifying probands by the presence and absence of these disorders. Results: ADHD in the proband significantly increased the risk for ADHD in relatives independently of the comorbidity with PSUD. PSUD in the proband was associated with a significantly increased risk for PSUD in relatives regardless of ADHD status. There was no evidence of co-segregation or non-random mating in the families of probands with ADHD and PSUD. Conclusions: Patterns of familial risk analysis suggest that the association between ADHD and PSUD in adolescent females is most consistent with the hypothesis that these disorders are independently transmitted, although the hypothesis of variable expressivity could not be ruled out. These findings are consistent with previously reported patterns of familial associations between ADHD and PSUD found in adolescent males. Longer follow-up periods are needed to more fully clarify the relationship between ADHD and PSUD, as well as provide adequate power for separate analyses of alcohol and drug use. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02040.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=720 [article] Familial risk analysis of the association between attention-deficit/hyperactivity disorder and psychoactive substance use disorder in female adolescents: a controlled study [Texte imprimé et/ou numérique] / Joseph BIEDERMAN, Auteur ; Michael C. MONUTEAUX, Auteur ; Stephen V. FARAONE, Auteur ; Carter R. PETTY, Auteur ; Eric MICK, Auteur ; Allison CLARKE, Auteur ; Kristina TEN HAAGEN, Auteur . - 2009 . - p.352-358. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 50-3 (March 2009) . - p.352-358 Mots-clés : ADHD substance-use female family-risk Index. décimale : PER Périodiques Résumé : Background: A robust and bi-directional comorbidity between attention-deficit/hyperactivity disorder (ADHD) and psychoactive substance use disorder (PSUD, alcohol or drug abuse, or dependence) has been consistently reported in the literature. However, this literature has been based almost exclusively on male only samples and, therefore, the findings may not generalize to females. Methods: First-degree relatives from a large sample of pediatrically and psychiatrically referred girls with (123 probands, 403 relatives) and without ADHD (112 probands, 359 relatives) were comprehensively assessed by blind raters with structured diagnostic interviews. Familial risk analysis examined the risks in first-degree relatives for ADHD and PSUD (alcohol or drug abuse or dependence) after stratifying probands by the presence and absence of these disorders. Results: ADHD in the proband significantly increased the risk for ADHD in relatives independently of the comorbidity with PSUD. PSUD in the proband was associated with a significantly increased risk for PSUD in relatives regardless of ADHD status. There was no evidence of co-segregation or non-random mating in the families of probands with ADHD and PSUD. Conclusions: Patterns of familial risk analysis suggest that the association between ADHD and PSUD in adolescent females is most consistent with the hypothesis that these disorders are independently transmitted, although the hypothesis of variable expressivity could not be ruled out. These findings are consistent with previously reported patterns of familial associations between ADHD and PSUD found in adolescent males. Longer follow-up periods are needed to more fully clarify the relationship between ADHD and PSUD, as well as provide adequate power for separate analyses of alcohol and drug use. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.02040.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=720

Psychiatric Comorbidity and Functioning in a Clinically Referred Population of Adults with Autism Spectrum Disorders: A Comparative Study / Gagan JOSHI in Journal of Autism and Developmental Disorders, 43-6 (June 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1314-1325 Titre : Psychiatric Comorbidity and Functioning in a Clinically Referred Population of Adults with Autism Spectrum Disorders: A Comparative Study Type de document : Texte imprimé et/ou numérique Auteurs : Gagan JOSHI, Auteur ; Janet WOZNIAK, Auteur ; Carter R. PETTY, Auteur ; Mary Kate MARTELON, Auteur ; Ronna FRIED, Auteur ; Anela BOLFEK, Auteur ; Amelia KOTTE, Auteur ; Jonathan STEVENS, Auteur ; Stephannie L. FURTAK, Auteur ; Michelle BOURGEOIS, Auteur ; Janet CARUSO, Auteur ; Ashley CARON, Auteur ; Joseph BIEDERMAN, Auteur Article en page(s) : p.1314-1325 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Psychiatric comorbidity  Adults Index. décimale : PER Périodiques Résumé : To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1679-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201 [article] Psychiatric Comorbidity and Functioning in a Clinically Referred Population of Adults with Autism Spectrum Disorders: A Comparative Study [Texte imprimé et/ou numérique] / Gagan JOSHI, Auteur ; Janet WOZNIAK, Auteur ; Carter R. PETTY, Auteur ; Mary Kate MARTELON, Auteur ; Ronna FRIED, Auteur ; Anela BOLFEK, Auteur ; Amelia KOTTE, Auteur ; Jonathan STEVENS, Auteur ; Stephannie L. FURTAK, Auteur ; Michelle BOURGEOIS, Auteur ; Janet CARUSO, Auteur ; Ashley CARON, Auteur ; Joseph BIEDERMAN, Auteur . - p.1314-1325. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1314-1325 Mots-clés : Autism spectrum disorders  Psychiatric comorbidity  Adults Index. décimale : PER Périodiques Résumé : To systematically examine the patterns of psychiatric comorbidity and functioning in clinically referred adults with autism spectrum disorders (ASD). Psychiatrically referred adults with and without ASD were compared on measures assessing for psychiatric comorbidity and psychosocial functioning. Sixty-three adults with ASD participated in the study (mean age: 29 ± 11 years). Adults with ASD in their lifetime suffered from a higher burden of psychiatric disorders (6 ± 3.4 vs. 3.5 ± 2.7; p 0.001) including major depressive disorder and multiple anxiety disorders, and were functionally more impaired with a significant proportion having received both counseling and pharmacotherapy. Adults with ASD have high levels of psychiatric comorbidity and dysfunction comparable to a clinically referred population of adults without ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1679-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201

The Heavy Burden of Psychiatric Comorbidity in Youth with Autism Spectrum Disorders: A Large Comparative Study of a Psychiatrically Referred Population / Gagan JOSHI in Journal of Autism and Developmental Disorders, 40-11 (November 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1361-1370 Titre : The Heavy Burden of Psychiatric Comorbidity in Youth with Autism Spectrum Disorders: A Large Comparative Study of a Psychiatrically Referred Population Type de document : Texte imprimé et/ou numérique Auteurs : Gagan JOSHI, Auteur ; Carter R. PETTY, Auteur ; Janet WOZNIAK, Auteur ; Aude HENIN, Auteur ; Ronna FRIED, Auteur ; Maribel GALDO, Auteur ; Meghan KOTARSKI, Auteur ; Sarah WALLS, Auteur ; Joseph BIEDERMAN, Auteur Année de publication : 2010 Article en page(s) : p.1361-1370 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Psychiatric comorbidity  Children and adolescents Index. décimale : PER Périodiques Résumé : The objective of the study was to systematically examine patterns of psychiatric comorbidity in referred youth with autism spectrum disorders (ASD) including autistic disorder and pervasive developmental disorder not otherwise specified. Consecutively referred children and adolescents to a pediatric psychopharmacology program were assessed with structured diagnostic interview and measures of psychosocial functioning. Comparisons were made between those youth satisfying diagnostic criteria for ASD and age and sex matched youth without ASD referred to the same clinical program. 9.3% (217/2323) of the referred youth (age range: 3–17 years) met DSM-III-R criteria for ASD. ASD youth suffered from significantly higher number of comorbid disorders than comparisons (6.4 ± 2.7 vs. 5.2 ± 2.9; p < 0.001). Ninety-five percent of the youth with ASD had three or more comorbid psychiatric disorders and 74% had five or more comorbid disorders. ASD youth were also more functionally impaired and required extra-assistance in school and therapeutic interventions at higher rates than age and sex matched non-ASD referred youth. Youth with ASD have high levels of psychiatric comorbidity and dysfunction comparable to the referred population of youth without ASD. These findings emphasize the heavy burden of psychiatric comorbidity afflicting youth with ASD and may be important targets for intervention. En ligne : http://dx.doi.org/10.1007/s10803-010-0996-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113 [article] The Heavy Burden of Psychiatric Comorbidity in Youth with Autism Spectrum Disorders: A Large Comparative Study of a Psychiatrically Referred Population [Texte imprimé et/ou numérique] / Gagan JOSHI, Auteur ; Carter R. PETTY, Auteur ; Janet WOZNIAK, Auteur ; Aude HENIN, Auteur ; Ronna FRIED, Auteur ; Maribel GALDO, Auteur ; Meghan KOTARSKI, Auteur ; Sarah WALLS, Auteur ; Joseph BIEDERMAN, Auteur . - 2010 . - p.1361-1370. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1361-1370 Mots-clés : Autism spectrum disorders  Psychiatric comorbidity  Children and adolescents Index. décimale : PER Périodiques Résumé : The objective of the study was to systematically examine patterns of psychiatric comorbidity in referred youth with autism spectrum disorders (ASD) including autistic disorder and pervasive developmental disorder not otherwise specified. Consecutively referred children and adolescents to a pediatric psychopharmacology program were assessed with structured diagnostic interview and measures of psychosocial functioning. Comparisons were made between those youth satisfying diagnostic criteria for ASD and age and sex matched youth without ASD referred to the same clinical program. 9.3% (217/2323) of the referred youth (age range: 3–17 years) met DSM-III-R criteria for ASD. ASD youth suffered from significantly higher number of comorbid disorders than comparisons (6.4 ± 2.7 vs. 5.2 ± 2.9; p < 0.001). Ninety-five percent of the youth with ASD had three or more comorbid psychiatric disorders and 74% had five or more comorbid disorders. ASD youth were also more functionally impaired and required extra-assistance in school and therapeutic interventions at higher rates than age and sex matched non-ASD referred youth. Youth with ASD have high levels of psychiatric comorbidity and dysfunction comparable to the referred population of youth without ASD. These findings emphasize the heavy burden of psychiatric comorbidity afflicting youth with ASD and may be important targets for intervention. En ligne : http://dx.doi.org/10.1007/s10803-010-0996-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113

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