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Auteur Susan F. TAPERT |
Documents disponibles écrits par cet auteur (6)



Depressive symptoms in adolescents: associations with white matter volume and marijuana use / Krista LISDAHL MEDINA in Journal of Child Psychology and Psychiatry, 48-6 (June 2007)
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[article]
Titre : Depressive symptoms in adolescents: associations with white matter volume and marijuana use Type de document : Texte imprimé et/ou numérique Auteurs : Krista LISDAHL MEDINA, Auteur ; Bonnie J. NAGEL, Auteur ; Ann PARK, Auteur ; Tim MCQUEENY, Auteur ; Susan F. TAPERT, Auteur Année de publication : 2007 Article en page(s) : p.592–600 Langues : Anglais (eng) Mots-clés : Adolescence depression cannabis marijuana-abuse neuroimaging MRI brain-imaging white-matter hippocampus Index. décimale : PER Périodiques Résumé : Depressed mood has been associated with decreased white matter and reduced hippocampal volumes. However, the relationship between brain structure and mood may be unique among adolescents who use marijuana heavily. The goal of this study was to examine the relationship between white matter and hippocampal volumes and depressive symptoms among adolescent marijuana users and controls.
Methods: Data were collected from marijuana users (n = 16) and demographically similar controls (n = 16) aged 16–18. Extensive exclusionary criteria included psychiatric and neurologic disorders, including major depression. Substance use, mood, and anatomical measures were collected after 28 days of monitored abstinence.
Results: Marijuana (MJ) users demonstrated more depressive symptoms than controls (p < .05). MJ use (β = .42, p < .005) and smaller white matter volume (β = −.34, p < .03) each predicted higher levels of depressive symptoms on the Hamilton Depression Rating Scale. MJ use interacted with white matter volume (β = −.55, p < .03) in predicting depression scores on the Beck Depression Inventory: among MJ users, but not controls, white matter volume was negatively associated with depressive symptoms.
Conclusions: Marijuana use and white matter volume were additive and interactive in predicting depressive symptoms among adolescents. Subtle neurodevelopmental white matter abnormalities may disrupt the connections between areas involved in mood regulation.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01728.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=103
in Journal of Child Psychology and Psychiatry > 48-6 (June 2007) . - p.592–600[article] Depressive symptoms in adolescents: associations with white matter volume and marijuana use [Texte imprimé et/ou numérique] / Krista LISDAHL MEDINA, Auteur ; Bonnie J. NAGEL, Auteur ; Ann PARK, Auteur ; Tim MCQUEENY, Auteur ; Susan F. TAPERT, Auteur . - 2007 . - p.592–600.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 48-6 (June 2007) . - p.592–600
Mots-clés : Adolescence depression cannabis marijuana-abuse neuroimaging MRI brain-imaging white-matter hippocampus Index. décimale : PER Périodiques Résumé : Depressed mood has been associated with decreased white matter and reduced hippocampal volumes. However, the relationship between brain structure and mood may be unique among adolescents who use marijuana heavily. The goal of this study was to examine the relationship between white matter and hippocampal volumes and depressive symptoms among adolescent marijuana users and controls.
Methods: Data were collected from marijuana users (n = 16) and demographically similar controls (n = 16) aged 16–18. Extensive exclusionary criteria included psychiatric and neurologic disorders, including major depression. Substance use, mood, and anatomical measures were collected after 28 days of monitored abstinence.
Results: Marijuana (MJ) users demonstrated more depressive symptoms than controls (p < .05). MJ use (β = .42, p < .005) and smaller white matter volume (β = −.34, p < .03) each predicted higher levels of depressive symptoms on the Hamilton Depression Rating Scale. MJ use interacted with white matter volume (β = −.55, p < .03) in predicting depression scores on the Beck Depression Inventory: among MJ users, but not controls, white matter volume was negatively associated with depressive symptoms.
Conclusions: Marijuana use and white matter volume were additive and interactive in predicting depressive symptoms among adolescents. Subtle neurodevelopmental white matter abnormalities may disrupt the connections between areas involved in mood regulation.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01728.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=103 Do traumatic events and substance use co-occur during adolescence? Testing three causal etiologic hypotheses / Susan F. TAPERT ; Sandra A. BROWN ; Sonya B. NORMAN ; William E. PELHAM III in Journal of Child Psychology and Psychiatry, 65-10 (October 2024)
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Titre : Do traumatic events and substance use co-occur during adolescence? Testing three causal etiologic hypotheses Type de document : Texte imprimé et/ou numérique Auteurs : Susan F. TAPERT, Auteur ; Sandra A. BROWN, Auteur ; Sonya B. NORMAN, Auteur ; William E. PELHAM III, Auteur Article en page(s) : p.1388-1397 Langues : Anglais (eng) Mots-clés : Trauma childhood adolescence alcohol cannabis nicotine etiology self-medication susceptibility shared liability Index. décimale : PER Périodiques Résumé : Background Why do potentially traumatic events (PTEs) and substance use (SU) so commonly co-occur during adolescence? Causal hypotheses developed from the study of posttraumatic stress disorder (PTSD) and substance use disorder (SUD) among adults have not yet been subject to rigorous theoretical analysis or empirical tests among adolescents with the precursors to these disorders: PTEs and SU. Establishing causality demands accounting for various factors (e.g. genetics, parent education, race/ethnicity) that distinguish youth endorsing PTEs and SU from those who do not, a step often overlooked in previous research. Methods We leveraged nationwide data from a sociodemographically diverse sample of youth (N?=?11,468) in the Adolescent Brain and Cognitive Development Study. PTEs and substance use prevalence were assessed annually. To account for the many pre-existing differences between youth with and without PTE/SU (i.e. confounding bias) and provide rigorous tests of causal hypotheses, we linked within-person changes in PTEs and SU (alcohol, cannabis, nicotine) across repeated measurements and adjusted for time-varying factors (e.g. age, internalizing symptoms, externalizing symptoms, and friends' use of substances). Results Before adjusting for confounding using within-person modeling, PTEs and SU exhibited significant concurrent associations (?s?=?.46?1.26, ps?.05) and PTEs prospectively predicted greater SU (?s?=?.55?1.43, ps?.05) but not vice versa. After adjustment for confounding, the PTEs exhibited significant concurrent associations for alcohol (?s?=?.14?.23, ps?.05) and nicotine (?s?=?.16, ps?.05) but not cannabis (?s?=?-.01, ps?>?.05) and PTEs prospectively predicted greater SU (?s?=?.28?.55, ps?>?.05) but not vice versa. Conclusions When tested rigorously in a nationwide sample of adolescents, we find support for a model in which PTEs are followed by SU but not for a model in which SU is followed by PTEs. Explanations for why PTSD and SUD co-occur in adults may need further theoretical analysis and adaptation before extension to adolescents. En ligne : https://doi.org/10.1111/jcpp.13985 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535
in Journal of Child Psychology and Psychiatry > 65-10 (October 2024) . - p.1388-1397[article] Do traumatic events and substance use co-occur during adolescence? Testing three causal etiologic hypotheses [Texte imprimé et/ou numérique] / Susan F. TAPERT, Auteur ; Sandra A. BROWN, Auteur ; Sonya B. NORMAN, Auteur ; William E. PELHAM III, Auteur . - p.1388-1397.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 65-10 (October 2024) . - p.1388-1397
Mots-clés : Trauma childhood adolescence alcohol cannabis nicotine etiology self-medication susceptibility shared liability Index. décimale : PER Périodiques Résumé : Background Why do potentially traumatic events (PTEs) and substance use (SU) so commonly co-occur during adolescence? Causal hypotheses developed from the study of posttraumatic stress disorder (PTSD) and substance use disorder (SUD) among adults have not yet been subject to rigorous theoretical analysis or empirical tests among adolescents with the precursors to these disorders: PTEs and SU. Establishing causality demands accounting for various factors (e.g. genetics, parent education, race/ethnicity) that distinguish youth endorsing PTEs and SU from those who do not, a step often overlooked in previous research. Methods We leveraged nationwide data from a sociodemographically diverse sample of youth (N?=?11,468) in the Adolescent Brain and Cognitive Development Study. PTEs and substance use prevalence were assessed annually. To account for the many pre-existing differences between youth with and without PTE/SU (i.e. confounding bias) and provide rigorous tests of causal hypotheses, we linked within-person changes in PTEs and SU (alcohol, cannabis, nicotine) across repeated measurements and adjusted for time-varying factors (e.g. age, internalizing symptoms, externalizing symptoms, and friends' use of substances). Results Before adjusting for confounding using within-person modeling, PTEs and SU exhibited significant concurrent associations (?s?=?.46?1.26, ps?.05) and PTEs prospectively predicted greater SU (?s?=?.55?1.43, ps?.05) but not vice versa. After adjustment for confounding, the PTEs exhibited significant concurrent associations for alcohol (?s?=?.14?.23, ps?.05) and nicotine (?s?=?.16, ps?.05) but not cannabis (?s?=?-.01, ps?>?.05) and PTEs prospectively predicted greater SU (?s?=?.28?.55, ps?>?.05) but not vice versa. Conclusions When tested rigorously in a nationwide sample of adolescents, we find support for a model in which PTEs are followed by SU but not for a model in which SU is followed by PTEs. Explanations for why PTSD and SUD co-occur in adults may need further theoretical analysis and adaptation before extension to adolescents. En ligne : https://doi.org/10.1111/jcpp.13985 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535 Incipient alcohol use in childhood: Early alcohol sipping and its relations with psychopathology and personality / Ashley L. WATTS in Development and Psychopathology, 33-4 (October 2021)
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Titre : Incipient alcohol use in childhood: Early alcohol sipping and its relations with psychopathology and personality Type de document : Texte imprimé et/ou numérique Auteurs : Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur Article en page(s) : p.1338-1350 Langues : Anglais (eng) Mots-clés : alcohol sipping novelty seeking personality precocious alcohol use psychopathology Index. décimale : PER Périodiques Résumé : Prior research has shown that sipping of alcohol begins to emerge during childhood and is potentially etiologically significant for later substance use problems. Using a large, community sample of 9- and 10-year-olds (N = 11,872; 53% female), we examined individual differences in precocious alcohol use in the form of alcohol sipping. We focused explicitly on features that are robust and well-demonstrated correlates of, and antecedents to, alcohol excess and related problems later in the lifespan, including youth- and parent-reported externalizing traits (i.e., impulsivity, behavioral inhibition and activation) and psychopathology. Seventeen percent of the sample reported sipping alcohol outside of a religiously sanctioned activity by age 9 or 10. Several aspects of psychopathology and personality emerged as small but reliable correlates of sipping. Nonreligious sipping was related to youth-reported impulsigenic traits, aspects of behavioral activation, prodromal psychotic-like symptoms, and mood disorder diagnoses, as well as parent-reported externalizing disorder diagnoses. Religious sipping was unexpectedly associated with certain aspects of impulsivity. Together, our findings point to the potential importance of impulsivity and other transdiagnostic indicators of psychopathology (e.g., emotion dysregulation, novelty seeking) in the earliest forms of drinking behavior. En ligne : http://dx.doi.org/10.1017/S0954579420000541 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457
in Development and Psychopathology > 33-4 (October 2021) . - p.1338-1350[article] Incipient alcohol use in childhood: Early alcohol sipping and its relations with psychopathology and personality [Texte imprimé et/ou numérique] / Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur . - p.1338-1350.
Langues : Anglais (eng)
in Development and Psychopathology > 33-4 (October 2021) . - p.1338-1350
Mots-clés : alcohol sipping novelty seeking personality precocious alcohol use psychopathology Index. décimale : PER Périodiques Résumé : Prior research has shown that sipping of alcohol begins to emerge during childhood and is potentially etiologically significant for later substance use problems. Using a large, community sample of 9- and 10-year-olds (N = 11,872; 53% female), we examined individual differences in precocious alcohol use in the form of alcohol sipping. We focused explicitly on features that are robust and well-demonstrated correlates of, and antecedents to, alcohol excess and related problems later in the lifespan, including youth- and parent-reported externalizing traits (i.e., impulsivity, behavioral inhibition and activation) and psychopathology. Seventeen percent of the sample reported sipping alcohol outside of a religiously sanctioned activity by age 9 or 10. Several aspects of psychopathology and personality emerged as small but reliable correlates of sipping. Nonreligious sipping was related to youth-reported impulsigenic traits, aspects of behavioral activation, prodromal psychotic-like symptoms, and mood disorder diagnoses, as well as parent-reported externalizing disorder diagnoses. Religious sipping was unexpectedly associated with certain aspects of impulsivity. Together, our findings point to the potential importance of impulsivity and other transdiagnostic indicators of psychopathology (e.g., emotion dysregulation, novelty seeking) in the earliest forms of drinking behavior. En ligne : http://dx.doi.org/10.1017/S0954579420000541 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum / Ashley L. WATTS in Development and Psychopathology, 33-3 (August 2021)
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Titre : Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum Type de document : Texte imprimé et/ou numérique Auteurs : Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur Article en page(s) : p.1139-1139 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579420001170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457
in Development and Psychopathology > 33-3 (August 2021) . - p.1139-1139[article] Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum [Texte imprimé et/ou numérique] / Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur . - p.1139-1139.
Langues : Anglais (eng)
in Development and Psychopathology > 33-3 (August 2021) . - p.1139-1139
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579420001170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study / Tiffany C. HO in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)
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Titre : Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study Type de document : Texte imprimé et/ou numérique Auteurs : Tiffany C. HO, Auteur ; Rutvik SHAH, Auteur ; Jyoti MISHRA, Auteur ; April C. MAY, Auteur ; Susan F. TAPERT, Auteur Article en page(s) : p.1523-1533 Langues : Anglais (eng) Mots-clés : Child Adolescent Humans Depression/psychology Magnetic Resonance Imaging/methods Family Conflict Brain/diagnostic imaging Cognition ABCD Study Adolescence depression functional MRI (fMRI) sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: While identifying risk factors for adolescent depression is critical for early prevention and intervention, most studies have sought to understand the role of isolated factors rather than across a broad set of factors. Here, we sought to examine multi-level factors that maximize the prediction of depression symptoms in US children participating in the Adolescent Brain and Cognitive Development (ABCD) study. METHODS: A total of 7,995 participants from ABCD (version 3.0 release) provided complete data at baseline and 1-year follow-up data. Depression symptoms were measured with the Child Behavior Checklist. Predictive features included child demographic, environmental, and structural and resting-state fMRI variables, parental depression history and demographic characteristics. We used linear (elastic net regression, EN) and non-linear (gradient-boosted trees, GBT) predictive models to identify which set of features maximized prediction of depression symptoms at baseline and, separately, at 1-year follow-up. RESULTS: Both linear and non-linear models achieved comparable results for predicting baseline (EN: MAE=3.757; R(2) =0.156; GBT: MAE=3.761; R(2) =0.147) and 1-year follow-up (EN: MAE=4.255; R(2) =0.103; GBT: MAE=4.262; R(2) =0.089) depression. Parental history of depression, greater family conflict, and shorter child sleep duration were among the top predictors of concurrent and future child depression symptoms across both models. Although resting-state fMRI features were relatively weaker predictors, functional connectivity of the caudate was consistently the strongest neural feature associated with depression symptoms at both timepoints. CONCLUSIONS: Consistent with prior research, parental mental health, family environment, and child sleep quality are important risk factors for youth depression. Functional connectivity of the caudate is a relatively weaker predictor of depression symptoms but may represent a biomarker for depression risk. En ligne : http://dx.doi.org/10.1111/jcpp.13608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1523-1533[article] Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study [Texte imprimé et/ou numérique] / Tiffany C. HO, Auteur ; Rutvik SHAH, Auteur ; Jyoti MISHRA, Auteur ; April C. MAY, Auteur ; Susan F. TAPERT, Auteur . - p.1523-1533.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1523-1533
Mots-clés : Child Adolescent Humans Depression/psychology Magnetic Resonance Imaging/methods Family Conflict Brain/diagnostic imaging Cognition ABCD Study Adolescence depression functional MRI (fMRI) sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: While identifying risk factors for adolescent depression is critical for early prevention and intervention, most studies have sought to understand the role of isolated factors rather than across a broad set of factors. Here, we sought to examine multi-level factors that maximize the prediction of depression symptoms in US children participating in the Adolescent Brain and Cognitive Development (ABCD) study. METHODS: A total of 7,995 participants from ABCD (version 3.0 release) provided complete data at baseline and 1-year follow-up data. Depression symptoms were measured with the Child Behavior Checklist. Predictive features included child demographic, environmental, and structural and resting-state fMRI variables, parental depression history and demographic characteristics. We used linear (elastic net regression, EN) and non-linear (gradient-boosted trees, GBT) predictive models to identify which set of features maximized prediction of depression symptoms at baseline and, separately, at 1-year follow-up. RESULTS: Both linear and non-linear models achieved comparable results for predicting baseline (EN: MAE=3.757; R(2) =0.156; GBT: MAE=3.761; R(2) =0.147) and 1-year follow-up (EN: MAE=4.255; R(2) =0.103; GBT: MAE=4.262; R(2) =0.089) depression. Parental history of depression, greater family conflict, and shorter child sleep duration were among the top predictors of concurrent and future child depression symptoms across both models. Although resting-state fMRI features were relatively weaker predictors, functional connectivity of the caudate was consistently the strongest neural feature associated with depression symptoms at both timepoints. CONCLUSIONS: Consistent with prior research, parental mental health, family environment, and child sleep quality are important risk factors for youth depression. Functional connectivity of the caudate is a relatively weaker predictor of depression symptoms but may represent a biomarker for depression risk. En ligne : http://dx.doi.org/10.1111/jcpp.13608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 Neural predictors of alcohol use and psychopathology symptoms in adolescents / T. Y. BRUMBACK in Development and Psychopathology, 28-4 pt1 (November 2016)
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