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Auteur Susan F. TAPERT |
Documents disponibles écrits par cet auteur (5)
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Depressive symptoms in adolescents: associations with white matter volume and marijuana use / Krista LISDAHL MEDINA in Journal of Child Psychology and Psychiatry, 48-6 (June 2007)
[article]
Titre : Depressive symptoms in adolescents: associations with white matter volume and marijuana use Type de document : Texte imprimé et/ou numérique Auteurs : Krista LISDAHL MEDINA, Auteur ; Bonnie J. NAGEL, Auteur ; Ann PARK, Auteur ; Tim MCQUEENY, Auteur ; Susan F. TAPERT, Auteur Année de publication : 2007 Article en page(s) : p.592–600 Langues : Anglais (eng) Mots-clés : Adolescence depression cannabis marijuana-abuse neuroimaging MRI brain-imaging white-matter hippocampus Index. décimale : PER Périodiques Résumé : Depressed mood has been associated with decreased white matter and reduced hippocampal volumes. However, the relationship between brain structure and mood may be unique among adolescents who use marijuana heavily. The goal of this study was to examine the relationship between white matter and hippocampal volumes and depressive symptoms among adolescent marijuana users and controls.
Methods: Data were collected from marijuana users (n = 16) and demographically similar controls (n = 16) aged 16–18. Extensive exclusionary criteria included psychiatric and neurologic disorders, including major depression. Substance use, mood, and anatomical measures were collected after 28 days of monitored abstinence.
Results: Marijuana (MJ) users demonstrated more depressive symptoms than controls (p < .05). MJ use (β = .42, p < .005) and smaller white matter volume (β = −.34, p < .03) each predicted higher levels of depressive symptoms on the Hamilton Depression Rating Scale. MJ use interacted with white matter volume (β = −.55, p < .03) in predicting depression scores on the Beck Depression Inventory: among MJ users, but not controls, white matter volume was negatively associated with depressive symptoms.
Conclusions: Marijuana use and white matter volume were additive and interactive in predicting depressive symptoms among adolescents. Subtle neurodevelopmental white matter abnormalities may disrupt the connections between areas involved in mood regulation.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01728.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=103
in Journal of Child Psychology and Psychiatry > 48-6 (June 2007) . - p.592–600[article] Depressive symptoms in adolescents: associations with white matter volume and marijuana use [Texte imprimé et/ou numérique] / Krista LISDAHL MEDINA, Auteur ; Bonnie J. NAGEL, Auteur ; Ann PARK, Auteur ; Tim MCQUEENY, Auteur ; Susan F. TAPERT, Auteur . - 2007 . - p.592–600.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 48-6 (June 2007) . - p.592–600
Mots-clés : Adolescence depression cannabis marijuana-abuse neuroimaging MRI brain-imaging white-matter hippocampus Index. décimale : PER Périodiques Résumé : Depressed mood has been associated with decreased white matter and reduced hippocampal volumes. However, the relationship between brain structure and mood may be unique among adolescents who use marijuana heavily. The goal of this study was to examine the relationship between white matter and hippocampal volumes and depressive symptoms among adolescent marijuana users and controls.
Methods: Data were collected from marijuana users (n = 16) and demographically similar controls (n = 16) aged 16–18. Extensive exclusionary criteria included psychiatric and neurologic disorders, including major depression. Substance use, mood, and anatomical measures were collected after 28 days of monitored abstinence.
Results: Marijuana (MJ) users demonstrated more depressive symptoms than controls (p < .05). MJ use (β = .42, p < .005) and smaller white matter volume (β = −.34, p < .03) each predicted higher levels of depressive symptoms on the Hamilton Depression Rating Scale. MJ use interacted with white matter volume (β = −.55, p < .03) in predicting depression scores on the Beck Depression Inventory: among MJ users, but not controls, white matter volume was negatively associated with depressive symptoms.
Conclusions: Marijuana use and white matter volume were additive and interactive in predicting depressive symptoms among adolescents. Subtle neurodevelopmental white matter abnormalities may disrupt the connections between areas involved in mood regulation.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01728.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=103 Incipient alcohol use in childhood: Early alcohol sipping and its relations with psychopathology and personality / Ashley L. WATTS in Development and Psychopathology, 33-4 (October 2021)
[article]
Titre : Incipient alcohol use in childhood: Early alcohol sipping and its relations with psychopathology and personality Type de document : Texte imprimé et/ou numérique Auteurs : Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur Article en page(s) : p.1338-1350 Langues : Anglais (eng) Mots-clés : alcohol sipping novelty seeking personality precocious alcohol use psychopathology Index. décimale : PER Périodiques Résumé : Prior research has shown that sipping of alcohol begins to emerge during childhood and is potentially etiologically significant for later substance use problems. Using a large, community sample of 9- and 10-year-olds (N = 11,872; 53% female), we examined individual differences in precocious alcohol use in the form of alcohol sipping. We focused explicitly on features that are robust and well-demonstrated correlates of, and antecedents to, alcohol excess and related problems later in the lifespan, including youth- and parent-reported externalizing traits (i.e., impulsivity, behavioral inhibition and activation) and psychopathology. Seventeen percent of the sample reported sipping alcohol outside of a religiously sanctioned activity by age 9 or 10. Several aspects of psychopathology and personality emerged as small but reliable correlates of sipping. Nonreligious sipping was related to youth-reported impulsigenic traits, aspects of behavioral activation, prodromal psychotic-like symptoms, and mood disorder diagnoses, as well as parent-reported externalizing disorder diagnoses. Religious sipping was unexpectedly associated with certain aspects of impulsivity. Together, our findings point to the potential importance of impulsivity and other transdiagnostic indicators of psychopathology (e.g., emotion dysregulation, novelty seeking) in the earliest forms of drinking behavior. En ligne : http://dx.doi.org/10.1017/S0954579420000541 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457
in Development and Psychopathology > 33-4 (October 2021) . - p.1338-1350[article] Incipient alcohol use in childhood: Early alcohol sipping and its relations with psychopathology and personality [Texte imprimé et/ou numérique] / Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur . - p.1338-1350.
Langues : Anglais (eng)
in Development and Psychopathology > 33-4 (October 2021) . - p.1338-1350
Mots-clés : alcohol sipping novelty seeking personality precocious alcohol use psychopathology Index. décimale : PER Périodiques Résumé : Prior research has shown that sipping of alcohol begins to emerge during childhood and is potentially etiologically significant for later substance use problems. Using a large, community sample of 9- and 10-year-olds (N = 11,872; 53% female), we examined individual differences in precocious alcohol use in the form of alcohol sipping. We focused explicitly on features that are robust and well-demonstrated correlates of, and antecedents to, alcohol excess and related problems later in the lifespan, including youth- and parent-reported externalizing traits (i.e., impulsivity, behavioral inhibition and activation) and psychopathology. Seventeen percent of the sample reported sipping alcohol outside of a religiously sanctioned activity by age 9 or 10. Several aspects of psychopathology and personality emerged as small but reliable correlates of sipping. Nonreligious sipping was related to youth-reported impulsigenic traits, aspects of behavioral activation, prodromal psychotic-like symptoms, and mood disorder diagnoses, as well as parent-reported externalizing disorder diagnoses. Religious sipping was unexpectedly associated with certain aspects of impulsivity. Together, our findings point to the potential importance of impulsivity and other transdiagnostic indicators of psychopathology (e.g., emotion dysregulation, novelty seeking) in the earliest forms of drinking behavior. En ligne : http://dx.doi.org/10.1017/S0954579420000541 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum / Ashley L. WATTS in Development and Psychopathology, 33-3 (August 2021)
[article]
Titre : Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum Type de document : Texte imprimé et/ou numérique Auteurs : Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur Article en page(s) : p.1139-1139 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579420001170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457
in Development and Psychopathology > 33-3 (August 2021) . - p.1139-1139[article] Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum [Texte imprimé et/ou numérique] / Ashley L. WATTS, Auteur ; Phillip K. WOOD, Auteur ; Kristina M. JACKSON, Auteur ; Krista M. LISDAHL, Auteur ; Mary M. HEITZEG, Auteur ; Raul GONZALEZ, Auteur ; Susan F. TAPERT, Auteur ; Deanna M. BARCH, Auteur ; Kenneth J. SHER, Auteur . - p.1139-1139.
Langues : Anglais (eng)
in Development and Psychopathology > 33-3 (August 2021) . - p.1139-1139
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579420001170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study / Tiffany C. HO in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)
[article]
Titre : Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study Type de document : Texte imprimé et/ou numérique Auteurs : Tiffany C. HO, Auteur ; Rutvik SHAH, Auteur ; Jyoti MISHRA, Auteur ; April C. MAY, Auteur ; Susan F. TAPERT, Auteur Article en page(s) : p.1523-1533 Langues : Anglais (eng) Mots-clés : Child Adolescent Humans Depression/psychology Magnetic Resonance Imaging/methods Family Conflict Brain/diagnostic imaging Cognition ABCD Study Adolescence depression functional MRI (fMRI) sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: While identifying risk factors for adolescent depression is critical for early prevention and intervention, most studies have sought to understand the role of isolated factors rather than across a broad set of factors. Here, we sought to examine multi-level factors that maximize the prediction of depression symptoms in US children participating in the Adolescent Brain and Cognitive Development (ABCD) study. METHODS: A total of 7,995 participants from ABCD (version 3.0 release) provided complete data at baseline and 1-year follow-up data. Depression symptoms were measured with the Child Behavior Checklist. Predictive features included child demographic, environmental, and structural and resting-state fMRI variables, parental depression history and demographic characteristics. We used linear (elastic net regression, EN) and non-linear (gradient-boosted trees, GBT) predictive models to identify which set of features maximized prediction of depression symptoms at baseline and, separately, at 1-year follow-up. RESULTS: Both linear and non-linear models achieved comparable results for predicting baseline (EN: MAE=3.757; R(2) =0.156; GBT: MAE=3.761; R(2) =0.147) and 1-year follow-up (EN: MAE=4.255; R(2) =0.103; GBT: MAE=4.262; R(2) =0.089) depression. Parental history of depression, greater family conflict, and shorter child sleep duration were among the top predictors of concurrent and future child depression symptoms across both models. Although resting-state fMRI features were relatively weaker predictors, functional connectivity of the caudate was consistently the strongest neural feature associated with depression symptoms at both timepoints. CONCLUSIONS: Consistent with prior research, parental mental health, family environment, and child sleep quality are important risk factors for youth depression. Functional connectivity of the caudate is a relatively weaker predictor of depression symptoms but may represent a biomarker for depression risk. En ligne : http://dx.doi.org/10.1111/jcpp.13608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1523-1533[article] Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study [Texte imprimé et/ou numérique] / Tiffany C. HO, Auteur ; Rutvik SHAH, Auteur ; Jyoti MISHRA, Auteur ; April C. MAY, Auteur ; Susan F. TAPERT, Auteur . - p.1523-1533.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1523-1533
Mots-clés : Child Adolescent Humans Depression/psychology Magnetic Resonance Imaging/methods Family Conflict Brain/diagnostic imaging Cognition ABCD Study Adolescence depression functional MRI (fMRI) sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: While identifying risk factors for adolescent depression is critical for early prevention and intervention, most studies have sought to understand the role of isolated factors rather than across a broad set of factors. Here, we sought to examine multi-level factors that maximize the prediction of depression symptoms in US children participating in the Adolescent Brain and Cognitive Development (ABCD) study. METHODS: A total of 7,995 participants from ABCD (version 3.0 release) provided complete data at baseline and 1-year follow-up data. Depression symptoms were measured with the Child Behavior Checklist. Predictive features included child demographic, environmental, and structural and resting-state fMRI variables, parental depression history and demographic characteristics. We used linear (elastic net regression, EN) and non-linear (gradient-boosted trees, GBT) predictive models to identify which set of features maximized prediction of depression symptoms at baseline and, separately, at 1-year follow-up. RESULTS: Both linear and non-linear models achieved comparable results for predicting baseline (EN: MAE=3.757; R(2) =0.156; GBT: MAE=3.761; R(2) =0.147) and 1-year follow-up (EN: MAE=4.255; R(2) =0.103; GBT: MAE=4.262; R(2) =0.089) depression. Parental history of depression, greater family conflict, and shorter child sleep duration were among the top predictors of concurrent and future child depression symptoms across both models. Although resting-state fMRI features were relatively weaker predictors, functional connectivity of the caudate was consistently the strongest neural feature associated with depression symptoms at both timepoints. CONCLUSIONS: Consistent with prior research, parental mental health, family environment, and child sleep quality are important risk factors for youth depression. Functional connectivity of the caudate is a relatively weaker predictor of depression symptoms but may represent a biomarker for depression risk. En ligne : http://dx.doi.org/10.1111/jcpp.13608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 Neural predictors of alcohol use and psychopathology symptoms in adolescents / T. Y. BRUMBACK in Development and Psychopathology, 28-4 pt1 (November 2016)
[article]
Titre : Neural predictors of alcohol use and psychopathology symptoms in adolescents Type de document : Texte imprimé et/ou numérique Auteurs : T. Y. BRUMBACK, Auteur ; Matthew WORLEY, Auteur ; Tam T. NGUYEN-LOUIE, Auteur ; Lindsay M. SQUEGLIA, Auteur ; Joanna JACOBUS, Auteur ; Susan F. TAPERT, Auteur Article en page(s) : p.1209-1216 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Adolescence is a period marked by increases in risk taking, sensation seeking, and emotion dysregulation. Neurobiological models of adolescent development propose that lagging development in brain regions associated with affect and behavior control compared to regions associated with reward and emotion processing may underlie these behavioral manifestations. Cross-sectional studies have identified several functional brain networks that may contribute to risk for substance use and psychopathology in adolescents. Determining brain structure measures that prospectively predict substance use and psychopathology could refine our understanding of the mechanisms that contribute to these problems, and lead to improved prevention efforts. Participants (N = 265) were healthy substance-naïve adolescents (ages 12–14) who underwent magnetic resonance imaging and then were followed annually for up to 13 years. Cortical thickness and surface area measures for three prefrontal regions (dorsolateral prefrontal cortex, inferior frontal gyrus, and orbitofrontal cortex) and three cortical regions from identified functional networks (anterior cingulate cortex, insular cortex, and parietal cortex) were used to predict subsequent binge drinking, externalizing symptoms, and internalizing symptoms. Thinner dorsolateral prefrontal cortex and inferior frontal cortex in early adolescence predicted more binge drinking and externalizing symptoms, respectively, in late adolescence (ps < .05). Having a family history of alcohol use disorder predicted more subsequent binge drinking and externalizing symptoms. Thinner parietal cortex, but not family history, predicted more subsequent internalizing symptoms (p < .05). This study emphasizes the temporal association between maturation of the salience, inhibition, and executive control networks in early adolescence and late adolescent behavior outcomes. Our findings indicate that developmental variations in these brain regions predate behavioral outcomes of substance use and psychopathology, and may therefore serve as prospective biomarkers of vulnerability. En ligne : http://dx.doi.org/10.1017/s0954579416000766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294
in Development and Psychopathology > 28-4 pt1 (November 2016) . - p.1209-1216[article] Neural predictors of alcohol use and psychopathology symptoms in adolescents [Texte imprimé et/ou numérique] / T. Y. BRUMBACK, Auteur ; Matthew WORLEY, Auteur ; Tam T. NGUYEN-LOUIE, Auteur ; Lindsay M. SQUEGLIA, Auteur ; Joanna JACOBUS, Auteur ; Susan F. TAPERT, Auteur . - p.1209-1216.
Langues : Anglais (eng)
in Development and Psychopathology > 28-4 pt1 (November 2016) . - p.1209-1216
Index. décimale : PER Périodiques Résumé : Adolescence is a period marked by increases in risk taking, sensation seeking, and emotion dysregulation. Neurobiological models of adolescent development propose that lagging development in brain regions associated with affect and behavior control compared to regions associated with reward and emotion processing may underlie these behavioral manifestations. Cross-sectional studies have identified several functional brain networks that may contribute to risk for substance use and psychopathology in adolescents. Determining brain structure measures that prospectively predict substance use and psychopathology could refine our understanding of the mechanisms that contribute to these problems, and lead to improved prevention efforts. Participants (N = 265) were healthy substance-naïve adolescents (ages 12–14) who underwent magnetic resonance imaging and then were followed annually for up to 13 years. Cortical thickness and surface area measures for three prefrontal regions (dorsolateral prefrontal cortex, inferior frontal gyrus, and orbitofrontal cortex) and three cortical regions from identified functional networks (anterior cingulate cortex, insular cortex, and parietal cortex) were used to predict subsequent binge drinking, externalizing symptoms, and internalizing symptoms. Thinner dorsolateral prefrontal cortex and inferior frontal cortex in early adolescence predicted more binge drinking and externalizing symptoms, respectively, in late adolescence (ps < .05). Having a family history of alcohol use disorder predicted more subsequent binge drinking and externalizing symptoms. Thinner parietal cortex, but not family history, predicted more subsequent internalizing symptoms (p < .05). This study emphasizes the temporal association between maturation of the salience, inhibition, and executive control networks in early adolescence and late adolescent behavior outcomes. Our findings indicate that developmental variations in these brain regions predate behavioral outcomes of substance use and psychopathology, and may therefore serve as prospective biomarkers of vulnerability. En ligne : http://dx.doi.org/10.1017/s0954579416000766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294